Essentials Of Pharmaceutical Preformulation

Essentials of Pharmaceutical Preformulation: A study guide for students and researchers in pharmacy and pharmaceutical sciences describes basic principles of pharmaceutical preformulation for undergraduate level pharmacy students and newly employed workers in the pharmaceutical field who do not have a pharmaceutical background. Successful preformulation requires knowledge of a number of concepts (solubility, partition coefficient, acid dissociation), familiarity with a range of analytical techniques and their application to dosage form design. This text takes these concepts and explains them in the context of pharmaceutical development .Special focus is given to the principles and use of analytical apparatus, providing a core set of transferable knowledge skills. The material is presented in the order that would be followed when developing a medicine and maps onto the indicative syllabus of pharmacy from the Royal Pharmaceutical Society It is divided into three sections: Basic concepts, Solid-state properties and Macroscopic properties and includes easy to follow text highlighted with relevant pharmaceutical examples

Dr Simon Gaisford from the University of London. Dr. Gaisford is a senior lecturer in Pharmaceutics. His research interests include: Thermal analysis, isothermal calorimetry, differential scanning calorimetry (DSC), solution calorimetry, titration calorimetry (ITC), dynamic mechanical analysis (DMA), thermal ink-jetting, polymorphism, amorphous content quantification, inhalation, oral fast-dissolving films, personalised-dose medicines

Mark Saunders?was awarded his first degree in Biological and Medicinal Chemistry from the University of Exeter and his PhD from the London School of Pharmacy under the supervision of Professors Kevin Taylor and Duncan Craig. His PhD programme was sponsored by GlaxoSmithKline and involved the design and characterisation of novel injectable lipid-based carrier vehicles for the treatment of Cystic Fibrosis.
After finishing his PhD, Mark consulted for the London based legal firm SJ Berwin, providing independant laboratory services in support of a successful major patent litigation trial on Paxil (Paroxetine Hydrochloride). After this, Mark was appointed Physical Scientist at a London based Contract Research Organisation (CRO), where he oversaw the growth and development of the company through to a commercial sell in 2007.
After spending 5 years in the Research and Development support arm of the company and having set up both the Physical Properties and Screening laboratories, Mark moved into Strategic Development where he directly lead the successful set up of a Japanese Business Development office in Tokyo. After 2 years in this position and havng seen the company grow significantly, Mark moved from this role and was involved in the commercial set up of Kuecept Ltd, of which he is a co-founder. Mark is also a member of UK and US Controlled Release Societies, Royal Society of Chemistry, Association of Pharmaceutical Scientists (APS), Internation Society of Aerosol Medicines, sits on the committee of the APS Materials Science Focus Group and has co-authored over 20 peer reviewed papers and 2 book chapters on preformulation.