Evidence-Based Pediatric Infectious Diseases

Evidence-based Pediatric Infectious Diseases is a practical guide to the diagnosis and management of childhood infections in clinical practice. Renowned Clinical Professor of Pediatric Infectious Diseases, David Isaacs, and an expert consultant editor team, bring you the first book to critically look at the evidence for decision making in pediatric infections.

Based around illustrative case studies, each chapter presents and analyzes current evidence on the management of different pediatric infections and provides firm treatment recommendations based on evidence of:
• efficacy and safety
• antibiotic resistance
• cost
• adverse effects
• ethical considerations.

Clear summaries and specific guidance allow you to assess the evidence for yourself and make rapid but informed management decisions based on the strength of evidence available. Antibiotic doses are presented clearly and simply, enabling you to select appropriate treatment at a glance.

This book uses a case-based approach that focuses on the most common disease areas affecting children in industrialized countries, developing countries, travelers and refugees. It is an up-to-date, relevant and widely applicable text that carefully examines the evidence for antibiotics and other interventions whilst encouraging a conservative and responsible approach to antibiotic use.

Evidence-based Pediatric Infectious Diseases is an indispensable resource for any practitioner who strives to provide the best evidence-based care for childhood infections.

David Isaacs is a senior staff physician in paediatric infectious diseases and immunology at The Children’s Hospital at Westmead, Sydney and Clinical Professor of Paediatric Diseases at the University of Sydney. He has published 10 books and over 200 peer-reviewed publications. His research interests are neonatal infections, respiratory virus infections, immunisations and ethics. He also has published on medical ethics. Professor Isaacs is on multiple national and international committees on infectious diseases and immunisations and is a reviewer for the Cochrane Collaboration.

Consultant Editors:
Elizabeth Elliott
Ruth Gilbert
Virginia Moyer
Michael Pichichero

About the authors.

Preface.

Acknowledgements.

Abbreviations.

1 Evidence-based practice.

2 Rational antibiotic use.

3 Cardiac infections.

4 Cervical infections.

5 Eye infections.

6 Fever.

7 Gastrointestinal infections.

8 HIV infection.

9 Immune deficiency.

10 Meningitis and central nervous system.

infections.

11 Osteomyelitis and septic arthritis.

12 Respiratory infections.

13 Sexually transmitted and genital infections.

14 Skin and soft tissue infections.

15 Systemic sepsis.

16 Tropical infections and travel.

17 Urinary tract infections.

18 Viral infections.

Appendix 1 Renal impairment and.

antimicrobials.

Appendix 2 Aminoglycosides: dosing and.

monitoring blood levels.

Appendix 3 Antimicrobial drug dose.

recommendations.

Index