商品簡介
A technique that is useful in the study of pharmaceutical products and biological molecules, polarization IR spectroscopy has undergone continuous development since it first emerged almost 100 years ago. Capturing the state of the science as it exists today, Linearly Polarized IR Spectroscopy: Theory and Applications for Structural Analysis demonstrates how the technique can be properly utilized to obtain important information about the structure and spectral properties of oriented compounds.
The book starts with the theoretical basis of linear-dichroic infrared (IR-LD) spectroscopy and then moves on to examine the background of the orientation method of colloid suspensions in a nematic host. It explores the orientation procedure itself, experimental design, and mathematical tools for the interpretation of the IR spectroscopic patterns. Next, the authors describe the structural elucidation of inorganic and organic compounds and glasses. Finally, they discuss applications in pharmaceutical analysis and the chemistry of dyes. Filled with more than 140 illustrations along with a color insert, the book explains both the scope of the polarized IR spectroscopy method as well as its limitations.
A powerful source of information not only for specialists in IR spectroscopy, but also for those working in the field of structural analysis, this volume moves the field closer to developing an inherently classical method for the structural characterization of compounds.
作者簡介
Bojidarka Ivanova, Ph.D. received her M.Sc. degree in physical and theoretical chemistry in 1997 from Sofia University (St. Kl. Okhridski), Bulgaria. She earned her Ph.D. in analytical chemistry from Sofia University in 2001. Since 2003, Dr. Ivanova has been an associate professor in chemistry, holding the corresponding position at the Department of Analytical Chemistry at Sofia University.
Tsonko Kolev, D.Sc. obtained his M.Sc. degree in chemistry in 1973 at Sofia University (St. Kl. Okhridski), Bulgaria, and his Ph.D. in organic chemistry in 1982 from the Institute of Organic Chemistry, Bulgarian Academy of Sciences. His current position is head of the Department of Organic Chemistry at Plovdiv University (P. Hilendarski), Bulgaria.
目次
Linear-Dichroic Infrared (IR-LD) Spectroscopy: BackgroundTheoretical PrerequisitesSymmetry Analysis of Normal Vibrations and Dipole Moments of Transition Generated TherefromElements and Operations of SymmetrySymmetry Analysis of the Dipole Moments of TransitionOrientation of the SamplesOrientation in Liquid Crystal SolutionsOrientation as Suspension in Liquid CrystalsPhotometrization and Processing of IR-LD Spectra: Differential Reducing ProcedureEffects in the Infrared Spectra of CrystalsBackground of the Orientation Method of Colloid Suspensions in a Nematic HostOrientation ProcedureValidation of the Orientation ProcedureAccuracy and RepeatabilityThe Quantitative Ratio of Liquid Crystals and Solid SamplesPreliminary Rubbing Out of the KBr PlatesPeak Function Type for the Curve-Fitting ProcedureNumber of Scans in the MeasurementsExperimental DesignMathematical Tools for the Interpretation of the IR Spectroscopic PatternsIR Spectra SubtractionThe Smoothing ProcedureAccuracy and PrecisionDeconvolutionCurve-Fitting Procedure (CFP)Baseline Correction (BLC)Reducing-Difference Procedure (RDP) for IR-LD Spectra InterpretationStructural Elucidation of Inorganic Compounds and GlassesInorganic CompoundsR Spectroscopic Elucidation of GlassesStructural Elucidation of Organic CompoundsAnalysis of Heterocyclic CompoundsSmall Biologically Active MoleculesApplication in the Pharmaceutical AnalysisAnalysis of Morphine AlkaloidsApplication in the Chemistry of DyesStilbazolium SaltsDicyanoisophorone DerivativesAppendix: List of AcronymsReferences
