ENZYME REACTOR ENGINEERING - PRINCIPLES AND APPLICATIONS

Enzyme Reactor Engineering: Principles and Applications is organized as an introductory overview, followed by two major parts – analysis of enzyme reaction kinetics and analysis of enzyme reactor performance. It concludes with a brief coverage of important mathematical concepts. This allows the reader to first get an insight of the detailed kinetics of the reaction brought about by a general enzyme at a given point; and then to extend this concept so as to encompass the overall reactor behavior.

It covers sequentially the three classical levels of description: macroscopic, or ideal; microscopic, or real in terms of hydrodynamics (including homogeneous, nontrivial flow patterns, as well as heterogeneous systems); and submicroscopic, or real in terms of mixing. The quality of the approximation increases in this order, but so does the complexity of the mathematical models entertained and the thoroughness of the experimental data required. Detailed examples and worked problems are given at the end of each section that utilize experimental kinetic data from processes of practical and industrial relevance. The major emphasis is on general simulation rather than empirical correlation. This approach rationally handles equations to eliminate overparameterization and establish dimensionless, simpler relationships; chooses problems of practical relevance, but in a way so as to cover various types of enzyme-mediated reaction processes and systems in a mathematically balanced fashion; and builds on specific cases for illustration purposes.

F. Xavier Malcata, PhD, is Full Professor at Department of Chemical Engineering, of the University of Porto in Portugal, and Researcher at LEPABE – Laboratory for Process Engineering, Environment, Biotechnology and Energy. His major areas of research encompass: theoretical simulation and optimization of enzyme reactors; optimization of thermodynamically and kinetically-controlled processes; and design and optimization of bio- and photobioreactors. He is the author of more than 400 highly cited journal papers, eleven books, four edited books, and fifty chapters in edited books. In 2011, he was awarded the Elmer Marth Educator Award by the International Association of Food Protection (USA), and in 2014, the William V. Cruess Award for excellence in teaching by the Institute of Food Technologists (USA).

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