Translational Bioinformatics and Its Application

This book offers a detailed overview of translational bioinformatics together with real-case applications. Translational bioinformatics integrates the areas of basic bioinformatics, clinical informatics, statistical genetics and informatics in order to further our understanding of the molecular basis of diseases. By analyzing voluminous amounts of molecular and clinical data, it also provides clinical information, which can then be applied. Filling the gap between clinic research and informatics, the book is a valuable resource for human geneticists, clinicians, health educators and policy makers, as well as graduate students majoring in biology, biostatistics, and bioinformatics.

Dongqing Wei is a professor at the State Key Laboratory of Microbial Metabolism and acting head of Department of Bioinformatics and Biostatistics, College of Life Science and Biotechnology, Shanghai Jiao Tong University. He also serves as the editor-in-chief for the journal “Interdisciplinary Sciences – Computational Life Sciences” and on the editorial board of several journals, such as the Journal of Molecular Graphics and Modeling, the Journal of Biomedical Science and Engineering and the International Journal of Biomedical Engineering and Consumer Health Informatics. His research interests focus on structural bioinformatics and biophysics, and he has published more than 150 research articles in leading journals.

Yilong Ma is an associate investigator at the Feinstein Institute for Medical Research. He is also core leader (PET) of the Imaging Core at the Feinstein Institute’s Halth Morris K. Udall Center of Excellence for Parkinson's Disease Research. Dr. Ma specializes in the development and application of innovative brain imaging methodology for mechanistic studies of neurodegenerative diseases. He has published over 80 peer-reviewed articles and book chapters on patient-oriented translational research in neurodegenerative and neuropsychiatric disorders.

William CS Cho is a scientific officer at the Department of Clinical Oncology at Queen Elizabeth Hospital. He serves as the editor-in-chief, editor and associate editor of a number of international medical journals, such as Translational Genetics and Genomics and Clinical Medicine Insights: Oncology. His research focuses on molecular oncology, tumor marker discovery and bioinformatics, and he has published more than 200 articles in these fields.

Qin Xu is an associate investigator at the College of Life Sciences and Biotechnology, Shanghai Jiao Tong University. His research focuses on computational structural biology. Dr. Xu has published more than 20 research articles in this field.