Vaccine Efficacy Evaluation：The Gnotobiotic Pig Model
商品資訊
系列名：Pocket Guides to Biomedical Sciences
ISBN13：9780367486341
出版社：PBKTYFRL
作者：Lijuan (Department of Biomedical Sciences and Pathobiology Yuan Virginia Tech Blacksburg Virginia USA)
出版日：2022/04/13
裝訂／頁數：平裝／184頁
商品簡介
Testing the immunogenicity, protective efficacy and safety in animal models is a crucial step in vaccine development. Pigs raised in germ-free environments, called gnotobiotic (Gn) pigs, are one of the most useful animal models for testing vaccines. The Gn pig model is a widely accepted model for studying pathogenesis and immunity and an ideal model for pre-clinical testing for the safety and efficacy of enteric viral vaccines. Through these studies and others, the Gn pig model has been established as the most reliable animal model for pre-clinical evaluation of human rotavirus and norovirus vaccines. This book provides detailed information on establishing Gn pig models, determining a proper virus inoculum pool and challenge dose, measuring protection and calculating efficacy, and delineating intestinal and systemic immune responses associated with the protection.
Key Features
- Provides a natural history of human rotavirus and norovirus infection in Gn pigs
- Establishes the optimal virus challenge doses in Gn pigs for vaccine evaluation
- Evaluates various candidate rotavirus and norovirus vaccines
- Discusses human gut microbiota transplanted Gn pig models
- Documents the role of probiotics and rice bran as prophylactics and vaccine adjuvants
購物須知
外文書商品之書封，為出版社提供之樣本。實際出貨商品，以出版社所提供之現有版本為主。部份書籍，因出版社供應狀況特殊，匯率將依實際狀況做調整。
無庫存之商品，在您完成訂單程序之後，將以空運的方式為你下單調貨。為了縮短等待的時間，建議您將外文書與其他商品分開下單，以獲得最快的取貨速度，平均調貨時間為1~2個月。
為了保護您的權益，「三民網路書店」提供會員七日商品鑑賞期(收到商品為起始日)。
若要辦理退貨，請在商品鑑賞期內寄回，且商品必須是全新狀態與完整包裝(商品、附件、發票、隨貨贈品等)否則恕不接受退貨。