Drug Target Selection and Validation

Table of Contents

DRUG DISCOVERY AND DESIGN SERIES Volume 1: Drug Target selection and validation.

1. Drug discovery paradigms: target-based drug discovery

Chonny Herrera-Acevedo, Camilo Perdomo-Madrigal, Jos?Alixandre de Sousa Luis, Luciana Scotti, Marcus Tullius Scotti

2. Drug discovery paradigms: phenotypic-based drug discovery

Alan Talevi, Carolina L. Bellera

3. Target Identification Approaches in Drug Discovery

Azhar Rasul, Ammara Riaz, Iqra Sarfraz, Samreen Gul Khan, Ghulam Hussain, Rabia Zara, Ayesha Sadiqa, Gul Bushra, Saba Riaz, Muhammad Javid Iqbal, Mudassir Hassan, Khatereh Khorsandi

4. Introduction to target validation

Cecilia Ort瞵, Santiago Ruatta, Marcelo Comini

5. Structure-based binding pocket detection and druggability assessment Santiago Rodriguez, Juan I. Alice, Carolina L. Bellera, Alan Talevi

6. Network-Based Target Identification

Zengrui Wu, Yun Tang

7. The Current State of Precision Medicine and Targeted-Cancer Therapies - Where are We?

Attila Seyhan

8. Metabolic Control Analysis for drug target selection against human diseases

Javier Belmont-D燰z, Citlali V嫙quez, Rusely Encalada, Rafael Moreno-S嫕chez, Paul A. M. Michels, Emma Saavedra

9. Progress on open chemoinformatic tools for drug discovery

Jos?L. Medina-Franco, Rodrigo Guti廨rez-Nieto, Homero G鏔ez-Velasco