Unlock the therapeutic potential of N-, O-, and S-based heterocycles with this comprehensive guide to the synthesis, characterization, and biological interactions of the compounds currently redefining modern drug design.
Heterocyclic compounds have proven their potential as active pharmaceutical ingredients due to the presence of N, O, and S in their chemical makeup, making them ideal hydrogen bond acceptors. Recently, a large number of heterocyclic compounds have been documented as drugs after clearing all phases of preclinical and clinical trials and are commercially available worldwide. This book provides a comprehensive look at the active profile of heterocyclic compounds and their potential applications as antibacterial, antiviral, anti-inflammatory, and anti-cancer agents, as well as applications in pharmaceutical chemistry, pharmacy, cheminformatics, bioinformatics, and related fields. It covers synthesis and characterization, biological interaction mechanisms, proteomics and genotypic activity, and their role in treating diseases including cancer and AIDS. It also addresses challenges such as bioavailability and toxicity, making it a valuable resource for researchers, students, and professionals in drug design using heterocycles.
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