Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

A daring criminal is making waves in the Big Forest! It’s up to Agent Moose and Owlfred to save the day in this third hilarious graphic novel chapter book from the author of My Big Fat Zombie Goldfish. Agent Moose and not-quite-so-special Agent Owlfred are back and better than ever!9781250222213 Agent Moose (精裝本)(graphic novel)A moose secret agent and his owl sidekick solve woodland mysteries in this hilarious new graphic novel chapter book series from the author of My Big Fat Zombie Goldfish. Meet Anonymoose─the best (worst) secret agent in the Big Forest. Along with Owlfred, his slightly more intelligent sidekick, this giant master of disguise has dedicated himself to solving all of Woodland HQ's mysteries!But this mystery is even more important than normal. Anonymoose's rival, Camo Cameleon, is being given a trophy for being the first agent to solve 100 cases─an honor that Anonymoose just barely missed out on!─and Anonymoose is sure that something fishy is going on.The cl

Mary Anne should never have thrown away that chain letter she got in the mail. Ever since she did, bad things have been happening―to everybody in the Baby-sitters Club. With Halloween coming up, Mary

Ten years after Alex and Aaron Stowe brought peace to Quill and Artimé, their younger twin sisters journey beyond Artimé in the sixth novel in the New York Times bestselling sequel series to The Unwan

從政治起源到選舉制度，多角度解答政治的十萬個為什麼。A Quick History of Politics takes us from pharaohs to fair votes, packed with facts and jokes about the many faces of politics through time.How did ancient people make decisions? How do the people in power stay in power? Why did Karl Marx have to go without trousers? A Quick History of Politics answers these questions and more, taking a ride through time from plutocrats to people power. What do you think of when you hear "politics?" Is it grey-haired men in suits, shouting at each other in a weird room? Well, you’re partly right… but there’s also a whole lot of crazy stories and weird history in the political world. A Quick History of Politics takes a look at the silly side of government, big and small, throughout the ages, and also explains the important stuff, like suffrage, elections and getting your voice heard. You will discover:How the earliest tribes got by without a leader.How the first ever kings and queens ruled their people.When and how de

How did a wealthy woman with the desire to help others became the founder of the Girl Scouts of the United States of America?Born in 1860 in Savannah, Georgia, Juliette Gordon Low grew up having the f

With more than 29 million books sold, the My Weird School series really gets kids reading In this eighth book in the My Weirder-est School series, A.J. and his friends join the Maker movement Who's re

A brilliantly fun search-and-find puzzle book for children from 6+, developed in consultation with the British Museum!Tom's not only lost in time, he's lost his cat, too! Can you find Tom and his naug

The newest book in the beloved Hilda series continues the action-packed adventures with our beloved Hilda stuck in the body of a troll trying to save all of human and troll-kind! See what perils await

Find out how stories about his son’s stuffed bear, famously known as Winnie the Pooh, made A. A. Milne one of the world’s best-known children’s authors.Born in England in 1882, Alan Alexander Milne gr

The puzzles and activities in this book will take you to the furthest corners of the Earth. You'll spot wildlife in the Amazon Rainforest and find a wonderful array of corals in the Great Barrier Reef

Tiny Gardening! is a fun kit that caters to ANY age, for curious minds that are interested in botany, gardening, plants and flowers, all in a cute, approachable format.Enjoy gardening at your fingerti

In the third installment of the exciting Dragon Kingdom of Wrenly graphic novel series, Ruskin and his friends compete in the legendary Night Hunt.Ruskin is excited to visit Crestwood to witness a ver

Before Mr. Lemoncello became everyone’s favorite game maker, he was a kid who liked to roll the dice . . . Discover the origins of what James Patterson calls “the coolest library in the world” in this PREQUEL to the New York Times bestselling Escape from Mr. Lemoncello’s Library.Go back to the START and meet thirteen-year-old, PUZZLE-obsessed Luigi Lemoncello! Luigi has a knack for games and puzzles. But sometimes it feels like the cards are stacked against him. UNTIL a carnival arrives in town and Luigi gets the CHANCE OF A LIFETIME—the opportunity to work for the world famous Professor Marvelmous--a dazzling, banana-hat-wearing barker who puts the SHOW in SHOWMAN! When the carnival closes, Professor Marvelmous leaves behind a mysterious puzzle box along with a clue. A clue that will lead Luigi and his friends on a fantastical treasure hunt to a prize beyond anything they could imagine--if they can find it! Can Luigi cr

This new title in the Who HQ Now format for trending topics details superstar Dwayne “The Rock” Johnson’s legendary career from the ring to the big screen.This new title in the Who HQ Now format for t

Critically acclaimed author Emma Otheguy joins Newbery Honor-winning Adam Gidwitz as co-author as the kids travel to Cuba to help the legendary Madre de aguas, now in paperback. In Cuba, it is believe

Who HQ brings you the stories behind the most beloved characters of our time.Find out how Alice in Wonderland became a children's classic.Published in 1865 by British author Lewis Carroll, this fantas

In his penultimate adventure, now in paperback, a devastated but determined Apollo travels to Camp Jupiter, where he must learn what it is to be a hero, or die trying."A clash of mythic intrigues and

A Newbery Honor Book and Walter Honor Book for Younger ReadersOne of the most acclaimed middle grade books of last year is now coming out in paperback. This is a gorgeously written, hopeful novel in v

Get ready for action, adrenaline and adventure in the latest explosive Alex Rider mission by bestselling author Anthony Horowitz, now in paperback. In this adrenaline-fuelled adventure in the number o

A boy who accidentally bonds with a magical Beast must set off on an adventure in the mysterious Woods in this whimsical and cheeky middle grade fantasy debutperfect for fans of Nevermoor and How to T

Now in hardcover for the first time, featuring new illustrations Return to the world of the Wingfeather Saga with Andrew Peterson and his all-star author friends. Immerse yourself in a land of bomnubb

Longlisted for Blue Peter Book Awards 2022Dive into the weird and wonderful world of sleep, from the science behind dreams to a peek into animal sleeping habits, in this incredible book for children aged 7 to 9. We spend about 26 years of our lives sleeping, but how much do you really know about what happens when your head hits the pillow? Flick through the charming illustrated pages and discover:- What is sleep, and why do we need it?- Who's still awake across the globe when you are tucked up in bed?- The history of sleep, including the evolution of the bed and the significance of dreams in myths and legends- How does sleep differ in the animal kingdom? From polyphasic sleeping lions and nocturnal raccoons to birds high in the sky and whales in the ocean- What happens to plants when the sun sets?- Practical tips and tricks to help you improve your bedtime routineThe Magic of Sleep answers all your questions about what goes on in your head when you snooze, including the difference betw

It's Billy's school camping trip. His worst nightmare is having to go to the TOILET in the DARK. What ifhe gets lost in the SCARY WOODS? What if there are WEREWOLVES? Or BEARS? The Mini Monstersdecide

With questions such as How do you write a song? and Can you play music in space? this book is perfect for encouraging an interest in music. Lift the flaps to discover instruments from around the world, and hear them come to life by listening to the book's playlist on Usborne.

Four best friends, two boybands, and an evil uncle with a monstrous secret - what could possibly go wrong? KID NORMAL meets THE X FACTOR in this hilarious new series for 8+ readers. This story begins with a pig in a basket, a forgetful grandma, and the hero of this adventure in a really bad mood. There is also a goose on the loose.We just wanted to warn you. Jamie McFlair's favourite band got a slot performing on the country's biggest talent show, but it went wrong thanks to Barry Bigtime (in an 'incident' involving a chocolate milkshake and worn underpants - don't ask). Barry is a music big shot, all round nasty man...and Jamie's Uncle.The next day, he launches his own massive new band and Jamie smells a rat. With the help of three trusty best friends - popular Daisy, no-nonsense Jenners, and timid Mel - Jamie vows to uncover Barry's dastardly plan. But Jamie doesn't know about BARRY'S SECRET.A secret that is TERRIBLE and SHOCKING and VERY STRANGE. There's something hidden in Barry's

Get whisked away through time in the magic tree house with Jack and Annie in the #1 bestselling series--and meet famous Founding Father and inventor Ben Franklin!When Jack and Annie are whisked back i

This official Minecraft novel is a journey into the unknown Max and Alison are proof that differences don't stand in the way of friendship. Max is always on the lookout for a new adventure--even if it means getting into trouble--while Alison prefers to follow the rules. But both of them are fascinated by the beat-up old journal Max finds and the strange gate its secretive author, the Enchanter, describes: a portal to an otherworldly realm of danger called the Nether. After they use the journal's instructions to craft the portal, Max and Alison squabble over whether to remain safe in the Overworld or to journey into the Nether to find the Enchanter . . . until a fateful accident makes the decision for them. Trapped in a scary new world, Max and Alison find an ally in Freya, a fierce warrior who has been living in the Nether with her beloved wolf, Bunny Biter. With Freya's help, and with the clues that lie in the pages of the mysterious journal, Max and Alison embark on a quest to find t

Evil wizard Astrid has trapped Drake's friends in stone and she is preparing to cast an even more dangerous spell! To stop her, Drake and Ana travel in search of Ka, a mysterious and greatly feared La

With more than 27 million books sold, the My Weird School series really gets kids reading In this seventh book in the My Weirder-est School series, A.J. and his friends learn some very weird ways to p

Book six in the OFFICIAL Minecraft fiction series for readers age 7+ Morgan, Ash, Harper, Po and Jodi return for their final adventure in the world of Minecraft. But something isn't right, and the gan

Ten years after Alex and Aaron Stowe brought peace to Quill and Artime, their younger twin sisters journey beyond Artime in the fifth novel in the New York Times bestselling sequel series to The Unwan

In the second book in the Dragon Kingdom of Wrenly graphic novel series, Ruskin, Cinder, and Groth are back for another exciting quest, this time to save a group of cursed shadow dragons!A royal erran

Rebel Girls Lead: 25 Tales of Powerful Women celebrates the incredible and inspiring stories of 25 women leaders in politics, business, sports, activism, and more, all written in fairy tale form. It i

A Finalist for the 2022 Jane Addams Children's Book AwardAn NPR Best Book of 2021A New York Times Best Children's Book of 2021A Washington Post Best Book of 2021A Kirkus Reviews Best Children's Book of 2021A Horn Book Fanfare Best Book of 2021In 1938, twenty-nine-year-old Nicholas Winton saved the lives of almost 700 children trapped in Nazi-occupied Czechoslovakia--a story he never told and that remained unknown until an unforgettable TV appearance in the 1980s reunited him with some of the children he saved.Czech-American artist, MacArthur Fellow, and Andersen Award winner Peter S s dramatizes Winton's story in this distinctive and deeply personal picture book. He intertwines Nicky's efforts with the story of one of the children he saved--a young girl named Vera, whose family enlisted Nicky's aid when the Germans occupied their country. As the war passes and Vera grows up, she must find balance in her dual identities--one her birthright, the other her choice.Nicky & Vera is a mas

Rafe Khatchadorian is back in the latest adventure in the bestselling Middle School seriesThings have quietened down for lovable troublemaker Rafe Khatchadorian, and after all the mishaps and adventur

Hilarious, illustrated school-based antics where everything that happens leads to DRAMA and RUNNING AROUND and even some FAINTING!When a session of extreme dancing leaves Maisie in hospital with a broken leg, things take a turn for the weird! Strange noises in the ward at night, missing cuddly toys and a sandwich trolley that only ever has TUNA sandwiches. Could Maisie’s leg be CURSED? If it is, and it DEFINITELY IS, then everything is DOOMED!Laugh-out-loud fun from Blue Peter Award winners Pamela Butchart and Thomas Flintham.Read more of Izzy’s adventures!Baby Aliens Got My TeacherThe Spy Who Loved School DinnersMy Headteacher Is a Vampire RatAttack of the Demon Dinner LadiesTo Wee Or Not To Wee!There’s a Werewolf In My Tent!The Phantom Lollipop Man!There’s a Yeti in the Playground!Icarus Was Ridiculous

On an island nation in the Indian Ocean, the explorers venture through a vast underwater world and take part in a friendly robotics competition. But the tides of good fortune change quickly. Suddenly,

Travel back in time in the magic tree house with Jack and Annie in this #1 bestselling series and meet the greatest warriors of all—the Romans!We are warriors! Jack and Annie have met knights, pirates

Think metric! A fun illustrated primer on the internationally recognized metric system for kids.Used in almost every country in the world, the metric system is an easy-to-use way of calculating length

The fifth arc in the sensational My Weird School series, which in its first four arcs has sold more than 23 million copies worldwide! In this sixth installment, A.J. and the gang begin music lessons!A