Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

A Finalist for the 2022 Jane Addams Children's Book AwardAn NPR Best Book of 2021A New York Times Best Children's Book of 2021A Washington Post Best Book of 2021A Kirkus Reviews Best Children's Book of 2021A Horn Book Fanfare Best Book of 2021In 1938, twenty-nine-year-old Nicholas Winton saved the lives of almost 700 children trapped in Nazi-occupied Czechoslovakia--a story he never told and that remained unknown until an unforgettable TV appearance in the 1980s reunited him with some of the children he saved.Czech-American artist, MacArthur Fellow, and Andersen Award winner Peter S s dramatizes Winton's story in this distinctive and deeply personal picture book. He intertwines Nicky's efforts with the story of one of the children he saved--a young girl named Vera, whose family enlisted Nicky's aid when the Germans occupied their country. As the war passes and Vera grows up, she must find balance in her dual identities--one her birthright, the other her choice.Nicky & Vera is a mas

Rafe Khatchadorian is back in the latest adventure in the bestselling Middle School seriesThings have quietened down for lovable troublemaker Rafe Khatchadorian, and after all the mishaps and adventur

Hilarious, illustrated school-based antics where everything that happens leads to DRAMA and RUNNING AROUND and even some FAINTING!When a session of extreme dancing leaves Maisie in hospital with a broken leg, things take a turn for the weird! Strange noises in the ward at night, missing cuddly toys and a sandwich trolley that only ever has TUNA sandwiches. Could Maisie’s leg be CURSED? If it is, and it DEFINITELY IS, then everything is DOOMED!Laugh-out-loud fun from Blue Peter Award winners Pamela Butchart and Thomas Flintham.Read more of Izzy’s adventures!Baby Aliens Got My TeacherThe Spy Who Loved School DinnersMy Headteacher Is a Vampire RatAttack of the Demon Dinner LadiesTo Wee Or Not To Wee!There’s a Werewolf In My Tent!The Phantom Lollipop Man!There’s a Yeti in the Playground!Icarus Was Ridiculous

On an island nation in the Indian Ocean, the explorers venture through a vast underwater world and take part in a friendly robotics competition. But the tides of good fortune change quickly. Suddenly,

Help your first grader build strong math foundations with Smart Start: Math Stories and Activities. Developed by teachers, the colorful activities introduce math skills in creative ways. Each unit introduces important math vocabulary and helps children recognize math in the world around them.Smart Start: Math Stories and Activities workbooks provide structured weekly activities to help children practice and learn numbers, counting, measurement, addition and subtraction, shape recognition, and graphing. Audio story read-alouds with colorful illustrations help students learn math concepts and make connections to the real world. Illustrated activities provide meaningful practice in a variety of formats, giving children multiple opportunities to achieve understanding.Math activities:Provide strong math foundations that teach the most important math skills.Include creative and fun lessons thathelp children create positive math connections.Use reward stickers to motivate children to complete

Travel back in time in the magic tree house with Jack and Annie in this #1 bestselling series and meet the greatest warriors of all—the Romans!We are warriors! Jack and Annie have met knights, pirates

Think metric! A fun illustrated primer on the internationally recognized metric system for kids.Used in almost every country in the world, the metric system is an easy-to-use way of calculating length

The fifth arc in the sensational My Weird School series, which in its first four arcs has sold more than 23 million copies worldwide! In this sixth installment, A.J. and the gang begin music lessons!A

The second installment in the highly illustrated Stick Dog series is now available in paperback!In this hilarious sequel, the dogs embark on their quest for hot dogs and they learn they’re not the onl

In Small Worlds Earth, explore nature up close. Look at what happens under the leaf litter in a forest, find out what lives in a single desert oasis, examine the top of a Brazil nut tree in the Amazon and much more. What will you find when you explore these small worlds? Prepare to be surprised by the variety of life on each page of this gorgeous lift-the-flap book.A fascinating exploration of the life and cycles in nature's small worlds.

It's Halloween and Billy can't wait for the village Halloween Party. There's just one problem... his Mini Monsters are at the party too! Sparkle-Bogey's in the apple bobbing, Trumpet's in a pumpkin an

A young meerkat travels the world looking for Christmas in this witty and festive picture book full of cards that readers can flip open to read!Sunny Meerkat isn't quite sure if Christmas in the Kalahari Desert with his meerkat family is the right sort of Christmas. After all, there's no snow, no Christmas trees, and certainly no holiday treats! Sunny sets off on a journey around the world visiting robins, penguins, and reindeer in search of the picture-perfect Christmas...before realizing he might have left it at home after all.

Ten years after Alex and Aaron Stowe brought peace to Quill and Artimé, their younger twin sisters journey beyond Artimé in the fourth novel in the New York Times bestselling sequel series to The Unwa

Winner of the Blue Peter Book Award 2021Short listed for Sainsbury's Children's Book Awards 2021If you've ever wanted to know what a panda does all day long, how your heart manages to shift all that blood around your body or what makes a rainbow shine, you've come to the right book. A Day in the Life of a Poo, a Gnu and You features the answers to all of these questions and many more, all told in a super-fun comic book format in three awesome sections: Human Body, Animal Kingdom and Earth and Science. A Day in the Life... is packed with facts, laughs and amazing illustrations you can dive into all day long. Meet your grumpy liver that has to do practically EVERYTHING; your trusty hands that are very, well, handy; the spiky porcupines ready to charge; lonely Mars rovers abandoned on the Red Planet; raging tornadoes ready to rip through the pages of the book and bubbly volcanoes ready to blow. All entries are told in the fun, friendly and informative style of Mike Barfield, and are broug

In 1975, under a bed in an old house in Tarrytown, New York, an unearthly tome entitled Ghostology was discovered, wrapped in a substance, later found to be ectoplasm. It is the life's work and study of American ghostologist Lucinda Curtle, who mysteriously passed to the Other Side during a seance. After her death, Ghostology seemingly became haunted by the ghost of Lucinda herself, who now wants to keep the secrets of the dead A SECRET.Now published, ghostwritten by Dugald Steer, the world itself can decide if Ghostology - purporting to tell the truth about ghosts - was solid fact or insubstantial fiction. Delve into the wealth of information and learn about different types of ghosts, ghosts around the world and ghost through history; haunted houses, ships and other objects (including books); the ghostologist's field kit; psychics and mediums; fakes and frauds; test your ghostological knowledge on one of Lucinda's own case studies. Complete with a jewel in the cover, as well as letter

Mac B. is on a secret mission to retrieve a stolen, priceless piece of history in this totally true kid spy adventure from New York Times bestselling author, Mac Barnett!England is in trouble! A price

It's called a crush for a reason...For the first time in her life, Natalie feels confident in her own skin. Her talents are being recognized, she has supportive friends, and she's spending a ton of ti

Girl by day. Cat by night. Ready for adventure. In the fourth book of this chapter book series, Kitty, a little girl with catlike superpowers, teams up with another superhero to save a bakery from certain disaster. Kitty and the Treetop Chase is perfect for newly independent readers and for fans of Rebecca Elliotts Owl Diaries. When a new family moves into town, Kitty is excited to make another friend. But George, Kittys new neighbor, is quiet and seems to have nothing in common with Kitty. When night approaches, Katsumi, a member of Kittys cat crew, tells Kitty about a dog causing a commotion in the bakery. Kitty decides to use her catlike superpowers to investigate, and it turns out that George has his own superpowers, too! Together, they set off to track down the mischievous dog before he can cause even more damage. Kitty and the Treetop Chase is the fourth book in a series about Kitty and her superhero adventures. With a charming main character, loads of cats, and striking two-colo

George and Harold's time-traveling Purple Potty lands them in a crazy place in the eighth book in this #1 New York Times bestselling series by Dav Pilkey, the author and illustrator of Dog Man!The tea

Dress the girl and boy dolls in wonderful traditional costumes for festivals and ceremonies around the world, including beautiful silk saris at an Indian wedding, fabulous flamenco dresses in Spain, a

Meet RORY BRANAGAN – he eats bad guys for breakfast. Well, not ACTUALLY. But he IS the best detective in town. Sixth in a hilarious comedy-crime series for readers of 8+.(This ebook is optimised for K

Daisy's in trouble again! Cheeky, extremely readable and funny young fiction from the bestselling author behind the hilarious OI FROG series.Daisy is going on holiday! In an actual plane to actual Spa

Book four in the OFFICIAL Minecraft fiction series for readers age 7+Morgan, Ash, Harper, Po and Jodi return in another adventure in the world of Minecraft. Portals opening... Worlds colliding! It sounds impossible, but the Evoker King has found a way from Minecraft into the real world! As Jodi races to piece together the clues to his identity, she doesn't like where they point.Could one of her friends be the sinister mob?!For fans of the Minecraft game, Jumanji and Wreck it Ralph.

Discover what lives and grows in the Congo Basin in Central Africa, one of the planet’s most remarkable regions.Running through six countries in the middle of Africa, the Congo Basin contains some of

What are reptiles? What do they eat? Find out about different reptiles on land and in water in this BBC Earth reader. The Ladybird Do You Know? graded readers series comprises a range of non-fiction

All four classic Frog and Toad stories are together in this four-book box set with a green handle and Velcro closure.Read all four of the Frog and Toad adventures in this box set that includes:Frog an

Leap into the world of Zeus the hamster and his gang of gods as they solve the mystery of the labyrinth in the second book in this hilarious modern-day take on Greek mythology. Our story begins in the

It’s the biggest livestream event ever—Mr. Lemoncello is going live with his first-ever televised BREAKOUT game!Discover what James Patterson calls “the coolest library in the world” in the fourth fun

Heartbreak and hope exist together in this remarkable graphic novel about growing up in a refugee camp, as told by a Somali refugee to the Newbery Honor-winning creator of Roller Girl.Omar and his you

Autism did not stop her—in fact, it helped Temple Grandin become a brilliant scientist and inventor.Temple Grandin wasn’t officially diagnosed with autism until she was in her 40s, but she knew at an

Katherine Applegate continues her epic New York Times bestselling middle grade animal fantasy series in this second installment, which Kirkus said in a starred review “will have readers salivating for

Catwad, the snarky blue furball with a funny take on just about everything, is BACK in this third graphic novel in an all-new series from New York Times bestselling author Jim Benton!Catwad and Blurmp

The mystery deepens and the action intensifies for 12-year-old Cruz Coronado and friends in the exciting third book in the Explorer Academy series.The adventure continues for Cruz, Emmett, Sailor, and

The third magical murder mystery in the bestselling Seth Seppi series, which started with The Last Chance Hotel!Seth and his talking cat Nightshade arrive in the magical town of Gramichee to gain an a

OLD books get NEW doodles - it's the classics as you've never seen them before!A hilarious new series that brings the classics to life with illustrations by Jack Noel. Perfect for fans of Tom Gates, Wimpy Kid and Dav Pilkey. And Charles Dickens.WHAT THE DICKENS?Ten-year-old Pip gets the fright of his life when he meets an escaped convict in a spooky graveyard. And that's just the beginning of an adventure that will lead him to a house full of secrets, a strange old lady and a journey to the big city to seek his fortune. But Pip is in for a BIG surprise . . .Join Pip in a rip-roaring story of family secrets, scary grannies and a REALLY annoying big sister in COMIC CLASSICS: GREAT EXPECTATIONS by Charles Dickens and Jack Noel.Look out for more COMIC CLASSICS:TREASURE ISLAND will have you HOOKED!Climb aboard with Jim Hawkins, a chatty parrot and a bunch of crazy pirates for a hilarious adventure across the seven seas.Get on the trail of THE HOUND OF THE BASKERVILLESSolve the case with Hol

Bjorn lives in a cave. The walls are soft, the ground is comfortable, and just in front there is new grass and a rough tree, perfect for back-scratching.A Bear Named Bjorn takes us into the forest wit

In this blockbuster instalment of the bestselling Middle School series, Rafe and all the favourite characters from James Patterson's books for kids get caught up in a hilarious adventure – together fo

All is chaos in Year 2! An unexpected visitor, a bewitched violin and an invasion of bunnies! What can it all mean??? Look out for other Wigglesbottom titles! The Shark in the Pool The Toilet Ghost Th

Dink, Josh, and Ruth Rose tackle an out-of-this-world mystery—in the twelfth A to Z Mysteries Super Edition!Mystery takes off in 3…2…1! Dink, Josh, and Ruth Rose are in Florida, visiting a space museu

Two fun-packed stories about Winnie, the world's wackiest witch, and her cat Wilbur. In Winderella, Winnie takes the starring role in a pantomime. But will there be a part for Wilbur? In Winnie's Book