Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Learn all about the history of voting rights in the United States—from our nation’s founding to the present day—in this powerful picture book from the New York Times bestselling author of The Pout-Pou

Duckling is splashing in a pond, Chick is learning to sing and Little Lamb is hopping happily. Spring is here, little ones! Turn the pages and watch the faces change in this playful board book about parent and child relationships and new life in spring. Simply by turning the page, the Venetian movement causes the animal's expressions to change in front of your eyes! Reading the humorous story and watching the animated illustrations with your child will help them learn about different facial expressions and the emotions they convey. Supports your child's emotional intelligence Builds cognitive skills Expands a child's knowledge of the world around them.

“Fantastical, thoughtful, and un-put-downable, I flew throughStormsongand want the third in the series NOW.” ―Elizabeth HoytA Reader's Digest Top 25 Best Fantasy Series Ever WrittenAfter spinning an enthralling world inWitchmark, the winner of the World Fantasy Award for best novel that was praised as a“can't-miss debut”byBooklist, and as“thoroughly charming and deftly paced”by theNew York Times, C. L. Polk continues the Kingston Cycle inStormsong. Magical cabals, otherworldly avengers, and impossible love affairs conspire to create a book that refuses to be put down.Dame Grace Hensley helped her brother Miles undo the atrocity that stained her nation, but now she has to deal with the consequences. With the power out in the dead of winter and an uncontrollable sequence of winter storms on the horizon, Aeland faces disaster. Grace has the vision to guide her parents to safety, but a hostile queen and a ring of rogue mages stand in the way of her plans. There's revolution in the air, and

Two hilarious stories about Winnie, the world's wackiest witch, and her cat Wilbur, taking on two special jobs at school. In Shark in the Bath, Winnie gets more than she bargains for when she agrees t

This scribble-in activity book is packed full of inventions to design or discover, from real historical breakthroughs to crazy contraptions to get you out of bed in the morning. The process of inventi

Two fun-packed stories about Winnie, the world's wackiest witch, and her cat Wilbur. In Winderella, Winnie takes the starring role in a pantomime. But will there be a part for Wilbur? In Winnie's Book

Zoooooooom! We're off on an exciting space adventure in our rocket to meet all the planets of the solar system.Join in with the rhymes and spot all the smiley-faced, friendly planets, from shimmering

★ 皇家學會科學圖書獎入圍作，最有故事性的數學史鉅作★ 從阿基米德到人工智慧，一口氣看懂微積分如何改變世界★ 沒有微積分，就沒有電腦、GPS、太空旅行與現代科技文明★ 天才、競爭、爭議與革命交織，一本讀來像史詩冒險的科普傑作這是一本把微積分寫得像歷史小說般精采的科普經典。史蒂芬．史卓格茲不只解釋數學，更帶領讀者看見天才們如何用思想改寫世界。從古代幾何到AI時代，本書呈現微積分如何成為現代文明最深層、也最驚人的力量。Shortlisted for the Royal Society Science Book Prize 2019A magisterial history of calculus (and the people behind it) from one of the world's foremost mathematicians. This is the captivating story of mathematics' greatest ever idea: calculus. Without it, there would be no computers, no microwave ovens, no GPS, and no space travel.But before it gave modern man almost infinite powers, calculus was behind centuries of controversy, competition, and even death. Taking us on a thrilling journey through three millennia, professor Steven Strogatz charts the development of this seminal achievement from the days of Archimedes to today's breakthroughs in chaos theory and artificial intelligence. Filled with idiosyncratic characters from Pythagoras to Fourier, Infinite Powers is a compelling

Have fun in the sun with Winnie, the world's wackiest witch, and her cat Wilbur. In Hot Cross Winnie, Winnie and Wilbur are hot and cross with each other. But when Wilbur disappears, Winnie will do an

Fort Fitzgerald is determined to uncover the truth, but a new student at school and the secrets he has to keep complicate matters in this second novel in a thrilling new series from the author of the

Ten years after Alex and Aaron Stowe brought peace to Quill and Artimé, their younger twin sisters journey beyond Artimé in the third novel in the New York Times bestselling sequel series to The Unwan

About this BookQuirky charm infuses this tale of Old Rock's life story, which is much more exciting than you'd expect.Old Rock has been sitting in the same spot in the pine forest for as long as anyon

This paperback junior novelization retells and expands upon the exciting story of Disney/Pixar Onward—in theaters March 6, 2020!Set in a suburban fantasy world, Disney/Pixar’s Onward introduces two te

How did Jackie Chan become one of the most recognizable and beloved actors in the world? Find out in this exciting biography of this martial artist turned international film superstar.When Kong-sang w

This deluxe Step into Reading leveled reader with over 30 stickers is based on Disney Mulan—just in time for the release of the live-action in March 2020!Join Mulan and her friends Mushu, Cri-Kee, and

Batter up! Baseball action and exciting whodunits star in this chapter book series! Next up is Colorado!Mike and Kate arrive in Colorado to a ballpark covered in snow! Luckily, the stadium has a heate

Preschoolers will delight in exploring a fun-filled spring day in this sturdy board book with colorful tabs featuring everyone's favorite monkey, Curious George.It is spring and George is excited for

In January 1980, a young police officer named John MacLennan committed suicide in his Ho Man Tin flat. His death came mere hours before he was to be arrested for committing homosexual acts still, at t

"Fans of Beatrix Potter will delight in this tribute to her dedication and talent, encapsulating a legacy that reaches far beyond the pages of her beloved books."-Foreword Reviews in a STARRED REVIEW"

🍩 多元活潑的教學活動和影音輔助 🍫讓發音學習就像美味的甜點一樣 無法抗拒！ ▌本教材讓初學者從字母讀寫出發，逐漸學習混音、拼音及閱讀簡單的句子，搭配可愛又美味的甜點圖示，帶領孩子輕鬆奠定自然發音技巧。 ▌全套共五冊，每冊八個單元，每兩個單元搭配 一次複習，共四次複習，每半冊有一個桌遊複習活動。▌各冊教學重點：第一冊認識 26 個字母及發音； 第二冊認識五個短母音；第三冊介紹長母音； 第四冊認識子音群；第五冊介紹長母音、雙母 音、 母音 + r。▌每冊學生課本後附一本讀本（含兩個故事），結合簡單的句型和所學的發音單字，讓孩子可以很快地學會自己朗誦故事。▌互動 App 內容包含音檔、閃示卡、發音單字動 畫、口訣歌謠、韻文動畫及互動遊戲，鼓勵學生課後複習。（建議使用 Wi-Fi 下載大容量檔案）▌教學配件豐富：支援多元創意的教學活動，透過琅琅上口的歌謠及引人入勝的故事，搭配桌 遊海報，讓發音練習不再枯燥無趣！▌提供團訂用戶的教學資源包含教師手冊、教案範例、課本及作業本解答、單元 / 分級測驗、 課程 MP3 音檔、閃示卡電子檔。For students• Student Book+ Readers + Poster + MP3 Download QR Code + Board Games• Workbook

An ode to the girl with scrapes on her knees and flowers in her hair, and every girl in between, this exquisite treasury will appeal to readers of Dear Girl and I Am Enough and have kids poring over i

Why is there so much plastic in the world? How does it help us? What's the problem and how can we solve it? These are just some of the 60+ questions answered in this timely and topical book. The

Sainsbury's Children's Book Awards 2021Lift the flaps and join in the fun with this special anniversary edition of the bestselling preschool classic, Fox's Socks by Julia Donaldson and Axel Scheffler, creators of The Gruffalo.Poor old Fox has lost his socks – can you help him find them? Are they in the kitchen or under the stairs? Are they inside the clock or hidden in a chest? Lift the flaps and find out!With sturdy flaps on every spread and rhyming stories that are a joy to read aloud, the Tales from Acorn Wood series has been delighting both parents and toddlers for over twenty years. Celebrate their unending appeal with Fox's Socks: 20th Anniversary Edition.Discover more stories in the Tales from Acorn Wood series: Rabbit's Nap: 20th Anniversary Edition, Hide-and-Seek Pig: 20th Anniversary Edition and Postman Bear: 20th Anniversary Edition.

The brilliantly funny fifth book in the SAM WU series, starring the bravest scaredy-cat in the world! Perfect for reluctant readers and fans of Tom Fletcher, Pamela Butchart and Humza Arshad's Badman.

Cowie is a donkey who feels like a cow on the inside. Will his friends help him make his dream come true? Find out in this sweetly told story about discovering your true self.Cowie was born a donkey but he knows he’s meant to be a cow. He wants to be a cow. Cows can graze in the meadow all day long and no one asks them to carry heavy packages. So, he stands with the cows in the barn but nothing happens. Will his dream ever come true, he wonders. Can Mousie and Duckie help Cowie feel happy in his own skin?

Each of the twelve stories in this collection is the perfect length for reading aloud in about five minutes, making them perfect for jam-packed days. This treasury stars beloved characters from the Di

Colors are everywhere, and not only will children learn to spot and identify colors in familiar settings, but they will learn to name objects as well in this color-themed matching game book. They can

Learn how to analyse and manage evolutionary and sequential user behaviours in modern networks, and how to optimize network performance by using indirect reciprocity, evolutionary games, and sequential decision making. Understand the latest theory without the need to go through the details of traditional game theory. With practical management tools to regulate user behaviour, and simulations and experiments with real data sets, this is an ideal tool for graduate students and researchers working in networking, communications, and signal processing.

Both utilitarian objects and examples of textile design of wondrous beauty, Chinese rank badges were developed in the Ming and Qing dynasties to indicate the bearer’s station in the civil or military

This textbook provides future data analysts with the tools, methods, and skills needed to answer data-focused, real-life questions; to carry out data analysis; and to visualize and interpret results to support better decisions in business, economics, and public policy. Data wrangling and exploration, regression analysis, machine learning, and causal analysis are comprehensively covered, as well as when, why, and how the methods work, and how they relate to each other. As the most effective way to communicate data analysis, running case studies play a central role in this textbook. Each case starts with an industry-relevant question and answers it by using real-world data and applying the tools and methods covered in the textbook. Learning is then consolidated by 360 practice questions and 120 data exercises. Extensive online resources, including raw and cleaned data and codes for all analysis in Stata, R, and Python, can be found at www.gabors-data-analysis.com.

This textbook provides future data analysts with the tools, methods, and skills needed to answer data-focused, real-life questions; to carry out data analysis; and to visualize and interpret results to support better decisions in business, economics, and public policy. Data wrangling and exploration, regression analysis, machine learning, and causal analysis are comprehensively covered, as well as when, why, and how the methods work, and how they relate to each other. As the most effective way to communicate data analysis, running case studies play a central role in this textbook. Each case starts with an industry-relevant question and answers it by using real-world data and applying the tools and methods covered in the textbook. Learning is then consolidated by 360 practice questions and 120 data exercises. Extensive online resources, including raw and cleaned data and codes for all analysis in Stata, R, and Python, can be found at www.gabors-data-analysis.com.

Data Science for Business with R, written by Jeffrey S. Saltz and Jeffrey M. Stanton, focuses on the concepts foundational for students starting a business analytics or data science degree program. To

Data Structures using Python provides an introduction to design, analysis, and implementation of data structures using the powerful programming language, Python. This book is designed for a first cour

How organizations--including Google, StubHub, Airbnb, and Facebook--learn from experiments in a data-driven world.Have you logged into Facebook recently? Searched for something on Google? Chosen a mov

In the global race to reach the end of AIDS, why is the world slipping off track? The answer has to do with stigma, money, and data. Global funding for AIDS response is declining. Tough choices must be made: some people will win and some will lose. Global aid agencies and governments use health data to make these choices. While aid agencies prioritize a shrinking list of countries, many governments deny that sex workers, men who have sex with men, drug users, and transgender people exist. Since no data is gathered about their needs, life-saving services are not funded, and the lack of data reinforces the denial. The Uncounted cracks open this and other data paradoxes through interviews with global health leaders and activists, ethnographic research, analysis of gaps in mathematical models, and the author's experience as an activist and senior official. It shows what is counted, what is not, and why empowering communities to gather their own data could be key to ending AIDS.

Drug Development for Cancer and Diabetes: A Path to 2030 focuses on new developments in the discovery of drugs for the treatment of cancer and diabetes. This new book presents important recent advance

In the global race to reach the end of AIDS, why is the world slipping off track? The answer has to do with stigma, money, and data. Global funding for AIDS response is declining. Tough choices must be made: some people will win and some will lose. Global aid agencies and governments use health data to make these choices. While aid agencies prioritize a shrinking list of countries, many governments deny that sex workers, men who have sex with men, drug users, and transgender people exist. Since no data is gathered about their needs, life-saving services are not funded, and the lack of data reinforces the denial. The Uncounted cracks open this and other data paradoxes through interviews with global health leaders and activists, ethnographic research, analysis of gaps in mathematical models, and the author's experience as an activist and senior official. It shows what is counted, what is not, and why empowering communities to gather their own data could be key to ending AIDS.

This book introduces the field of data science in a practical and accessible manner, using a hands-on approach that assumes no prior knowledge of the subject. The foundational ideas and techniques of data science are provided independently from technology, allowing students to easily develop a firm understanding of the subject without a strong technical background, as well as being presented with material that will have continual relevance even after tools and technologies change. Using popular data science tools such as Python and R, the book offers many examples of real-life applications, with practice ranging from small to big data. A suite of online material for both instructors and students provides a strong supplement to the book, including datasets, chapter slides, solutions, sample exams and curriculum suggestions. This entry-level textbook is ideally suited to readers from a range of disciplines wishing to build a practical, working knowledge of data science.

WS Education 精心策畫World of Discovery (探索世界) 系列讀物，全套共51冊，根據不同的閱讀能力分為三個等級：A (Achieving 達成), B (Blooming 增進), C (Confident自信) ，讓孩子從有趣的閱讀體驗中認識亞洲以及探索STEM（科學、技術、工程和數學）。本系列由新加坡國立教育學院(NIE)英文系退休教授 Ruth YL Wong 博士指導，適合3至8歲及以上的孩子閱讀，書中提供說故事的指南與單詞解釋詞彙表，適合家庭、學校和公共圖書館，從有趣的閱讀中認識英文詞彙，並提升孩子對兒童對科學探索與認識全球多元文化。Level C (Confident 自信)Level C適用對閱讀有信心的小讀者，他們能夠獨立讀出書中至少90%的單詞，及閱讀較長的句子和文章。這三套的故事旨在向小讀者介紹科技，鼓勵他們想像、探索自然、科學發明。Level C 分為三套書共有12冊，本書預期可以讀者達成以下目標：• 可以指出朗讀的單詞• 讀出至少 90% 的單詞• 閱讀更長的句子和更長的文本• 享受閱讀• 獨立閱讀The World of Discovery Collection is a specially curated selection of children's books that focus on discovering Asia and discovering STEM (Science, Technology, Engineering and Maths). Under the guidance of Dr Ruth Y L Wong, these books aim to promote reading for pleasure, while exciting kids through discovery. With 51 books in this inaugural batch, and with more to come, the books are divided into three levels depending on the child's reading ability: A (Achieving), B (Blooming) and C (Confident). Level C Set 1

Discover the fascinating world of our furry companions withWoof! The Truth About DogsbyAnnette Whipple. This engaging and informative book is filled with fun facts, photographs, illustrations, and all the answers to your burning questions about man’s best friend.Amusing & Informative:Written in an engaging question-and-answer format, this book is both entertaining and educational. Readers will learn about various aspects of dogs' behavior, communication, and history.Vibrant Illustrations:Colorful photographs and illustrations bring the world of dogs to life on the pages, capturing the attention of young readers and enhancing their understanding of the topics discussed.Extra Insights:In addition to the author's informative text, readers will enjoy hearing from the dogs themselves, who provide additional insights and perspectives on their behavior and experiences.Perfect for Ages 8-12:Geared towards children aged 8-12 and grade levels 2-4,Woof! The Truth About Dogsis accessible and e