Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

"A bold and subversive retelling of the goddess's story," this #1 New York Times bestseller "manages to be both epic and intimate in its scope, recasting the most infamous female figure from the Odyss

The Hearth Witch's Kitchen Herbal is an herbal with a difference—it shows how to use the herbs and spices most of us already have in our kitchens for home remedies, personal care, spiritual practice,

This playful book takes little children on a hide-and-seek adventure in search of the elusive little tiger. Die-cut holes on each page seem to reveal the tiger, only for it to turn out to be a differe

In August 1994, Manic Street Preachers released The Holy Bible, a dark, fiercely intelligent album that explored such themes as mental illness, murder and war. Richey Edwards, the band's lyricist and

Ram the farmer is in trouble. Bali the tiger has threatened to eat him, his wife and their children, unless Ram gives up his pretty white cow. But Reeta, Ram's clever wife, has a plan to outwit the hu

An imaginative story, ideal for children practising their reading at home or in school.When Jack kicks his ball over the garden wall, he meets Abbie, his mysterious neighbour, who gives him a glimpse

Andie dreams of becoming an artist. Her best paintings are inspired by the moon, and she’s excited to watch the first moon landing. She loves staying in Chelsea, with its fashion, music and art galler

The brilliant and hilarious debut from a rising star of the picture book world. Isobel's grandma has lost her glasses and she can't see a thing without them. While Isobel and Gran are in the garden se

Ruby Palace is no place for pets! But Princess Bea won't let royal rules stop her from helping animals in need... When Bea rescues a lost kitten, she promises to keep it safe until she can find its ow

When Crab finds a new shell, he doesn’t want to share it with anyone – especially not a blobby purple anemone and a tickly bristleworm. But life in the rock pool proves tougher than Crab thinks and he

Peep through the beautifully laser-cut pages to see Jack in his cottage, climb the beanstalk, enter the giant's house, and escape with the golden-egg-laying hen! This classic tale is charmingly, chara

Meekoo may be a big bear now, but even big bears have accidents sometimes. Everyone will enjoy the soundtrack to Meekoo's potty-training day - and they'll love joining in with the big cheer at the end!

Celebrate like they do in The Big Easy with Chef Kevin Belton’s newest cookbook.The spotlight in this third book from the star of New Orleans Cooking with Kevin Belton is on the festivals and celebrations of the Big Easy and surrounding areas. New Orleans is known as the Festival Capital of the World, hosting dozens of annual festivals that showcase the unique food and multicultural heritage of the city.Kevin Belton’s New Orleans Celebrations will be a smorgasbord of delicious creations from vibrant festivals like the French Market Creole Tomato Festival, Bastille Day Fête, the Crescent City Blues and BBQ Festival, and more. Recipes include Ham Croquettes with Pear Pepper Jelly, Bacon and Barbecue Quiche, Crawfish Enchiladas and Creole Tomato, and Crawfish Macaroni and Cheese.

From demolishing a building to constructing a skyscraper, this fun activity book—with more than 250 stickers—shows children how things get built! Excavate. Lay the foundation. Create beautiful bridges and structures. This colorful sticker book takes children right onto a construction site to follow the entire building process from start to finish. They’ll even learn what dangers lurk in the scaffolding, machines, planks, and concrete! As they go along, kids can use the stickers to decorate the scenes in any way they like. Each spread features things to look for, find, and count, as well as fun facts and questions. A treasure hunt activity at the end encourages youngsters to go back and spot things they may not have noticed before.

Pudding Tat is born on the Willoughby Farm in 1901 — just another one of Mother Tat’s kittens. But it turns out that Pudding is anything but ordinary. He is pure white with pink eyes that, though beautiful, do not see well, and hearing that is unusually acute. He finds himself drawn to the sweet sounds of the world around him — the pattering heartbeat of a nearby mouse, the musical tinkling of a distant stream.Soon the sounds of adventure call to Pudding, too. But before he can strike out into the wide world on his own, he hears a voice — coming from right inside his own ear. A flea has claimed Pudding as his host. The bossy parasite demands that Pudding take him away from the lowly barn and the drunken singing of his fellow fleas. He doesn’t want adventure but a finer life — one where he can enjoy a warm bed and blood flavored not with mice, but with beef tenderloin and cream.Fortunately for this mismatched pair, the world is an extremely interesting place in 1901. Over the next decad

In this heartwarming follow-up to Laurel Snyder's awardwinning beginning chapter book Charlie & Mouse, the two brothers prepare to celebrate one very special birthday: their mom's! Follow along as the

Brush up your knowledge on popular American painter and illustrator Norman Rockwell with this exciting Who Was? title.Norman Rockwell often painted what he saw around him in nostalgic and humorous way

From popular author Ame Dyckman and rising star Charles Santoso comes the laugh-out-loud story of a father desperate to destroy the dandelion marring his perfectly manicured lawn, and his daughter's fierce attempts to save it. When Daddy spots a solitary weed in his lawn, he's appalled (along with all of his neighborhood friends). But his daughter Sweetie has fallen in love with the beautiful flower, even going so far as to name it Charlotte. Racing against time and the mockery of his friends, Daddy has to find a way to get rid of the errant dandelion without breaking his little girl's heart.

A beautifully-illustrated story about a girl who longs for magic in her life and learns that, on the inside, she already is what she wishes she could be. Reminiscent of Studio Ghibli, this lushly-draw

“An intense snapshot of the chain reaction caused by pulling a trigger.” —Booklist (starred review)“Astonishing.” —Kirkus Reviews (starred review)“A tour de force.” —Publishers Weekly (starred review)A Newbery Honor BookA Coretta Scott King Honor BookA Printz Honor BookA Los Angeles Times Book Prize Winner for Young Adult LiteratureLonglisted for the National Book Award for Young People’s LiteratureWinner of the Walter Dean Myers AwardAn Edgar Award Winner for Best Young Adult FictionParents’ Choice Gold Award WinnerAn Entertainment Weekly Best YA Book of 2017A Vulture Best YA Book of 2017A Buzzfeed Best YA Book of 2017An ode to Put the Damn Guns Down, this is New York Times bestselling author Jason Reynolds’s electrifying novel that takes place in sixty potent seconds—the time it takes a kid to decide whether or not he’s going to murder the guy who killed his brother.A cannon. A strap.A piece. A biscuit.A burner. A heater.A chopper. A gat.A hammerA toolfor RULEOr, you can call it a gu

NATIONAL BEST SELLERFrom the internationally acclaimed, best-selling author of The English Patient: a mesmerizing new novel that tells a dramatic story set in the decade after World War II through the

Introducing a delightful collection of nursery rhymes, ideal for reading with young children. With 24 nursery rhymes in the book, children will have fun revisiting old favourites and learning new ones

Observing that the division between theory and empiricism remains inextricably linked to imperial modernity, manifest at the most basic level in the binary between “the West” and “Asia,” the authors o

Now in its seventh edition—with more than one million copies sold worldwide—The Relaxation and Stress Reduction Workbook remains the go-to resource for stress reduction strategies that can be incorpor

STAEDTLER─Made in Germany 施德樓─對品質的堅持座落於Nuremberg 的企業總部，我們很驕傲的說，我們仍堅持在德國製造，那種對品質堅守承諾的傳統。相較於全世界各大品牌，紛紛以成本考量，寧願犧牲品質的現實考量，作為德國紐倫堡施德樓基金會的公司─"Made in Germany"是一種象徵著品質的使命與榮耀，我們有75％的產品，仍堅持著由這裡生產來發送全世界。品名：施德樓

The Assassin tells the story of a swordswoman who refrains from killing. Hou Hsiao-hsien astonishes his audience once again by upsetting almost every convention of the wuxia (martial arts) genre in th

The students are sick and tired of Spaghetti-and-Meatball Mondays in the cafeteria. The administration says they can help create a new menu, so students throughout the school make booths with their fa

There was an old lady who swallowed a cake. I don't know why she swallowed the cake. It was a mistake!Scholastic's Old Lady is more popular than ever, and in celebration she's swallowing a cake... and

When Cyril, Anthea, Robert and Jane accidentally destroy a carpet in their London home with fireworks, their parents replace it with a second-hand one. Upon unfurling it, the children find an egg insi

Be brave and keep the seas safe!Nixie can't wait to join the Royal Mermaid Rescue Crew. Along with a magical seapony partner, she'll save merpeople in danger and use her natural creativity to keep the

"If you want us to remain silent - if you want to retain your freedom, your job, and your reputation - you need to tell us everything, and I mean everything. . ."We last saw Eve and Villanelle in a sp

An adorable board book for the babies and toddlers of gay fathers, featuring a variety of diverse, loving families with two dads.Families with same-sex parents are celebrated in this board book that f

STAEDTLER─Made in Germany 施德樓─對品質的堅持座落於Nuremberg 的企業總部，我們很驕傲的說，我們仍堅持在德國製造，那種對品質堅守承諾的傳統。相較於全世界各大品牌，紛紛以成本考量，寧願犧牲品質的現實考量，作為德國紐倫堡施德樓基金會的公司─"Made in Germany"是一種象徵著品質的使命與榮耀，我們有75％的產品，仍堅持著由這裡生產來發送全世界。品名：施德樓

引領搭配詞運用潮流、各界爭相學習仿效的，「搭配詞的力量」系列，再次出擊！本次《搭配詞的力量Collocations：名詞篇 全新升級版》，特別加錄美式英語錄音，讓你眼耳鼻舌心，全面學習搭配詞，改變一生的學習觀念，不再年年學英文，年年從頭學！◆什麼是搭配詞？什麼時候會用到搭配詞？ 你知道嗎？中文說「恢復某人記憶」時，英文用「refresh one’s memory」來表示；而中文的「活化經濟」，英文母語人士常說「invigorate economy」；中文的「燙手山芋」，英文使用「a pain in the neck」。 上述這樣一個「單字」加上「慣用法」所形成的固定詞組，我們統稱為「搭配詞」，如果搭配詞太少，使用英文容易語塞或出現「台式英文」。◆搭配詞如何給你力量？為何搭配詞那麼重要呢？ 在學習英文的道路上，你曾遇過以下困擾嗎？ 想要講一句話，但是語塞講不出來，因為「不知道要用什麼字表達心中所想的東西」。 有時會覺得自己的英文看似「字字是英文」，但其實「句句不是英文」，不知如何道地、精準地使用英文。　知道的單字不少，但是真的用出來的總是那些。 如果以上問題你都感同身受，代表你非常需要這本書！ 有了搭配詞，你不會再害怕開口說英文，說英文就像是呼吸一樣自然；出國在外，跟外國人交談再也不用支支吾吾，很順利地就能講出流利的句子。這，就是搭配詞的力量。 有別於一般搭配詞辭典過度厚重、資訊繁多、不適合學習者研讀，本書系統性地整理出台灣人最需要的搭配詞用法，從此擺脫「字字是英文，句句非英文」！◆台式英文OUT！搭配詞改變你學英文的習慣！ 本書是搭配詞的名詞篇，以詞彙的開頭字母分類，分成A～U，每個名詞詞彙又囊括了以下架構：1. 搭配詞 當名詞前後加上了動詞、形容詞及慣用法，就形成了一個固定詞組，也就是搭配詞。學會了搭配詞，英文自然脫口而出，不再東拼西湊出錯誤的句子。 例： Belief 信念、看法 Adj. + belief firm belief 堅定的信念 unshakable / unwavering belief 不可動搖的信念 widely held belief 普遍看法 V. + belief hold belief 抱持信念 adhere to / cling to

A fairytale full of adventure! Once upon a time, Peppa, George, Mummy Pig and Daddy Pig were on a magical adventure in the fairy-tale woods . . . First they met a big (but not very bad) wolf, and then

本書獻給每個人身體裡都有的一種科學怪咖特質。每個事物的起點是某人的白日夢。幻想非常重要，但科幻小說合理性息息相關。科幻小說中的科學不需要可信度，但是它需要是可以探索主題的工具。大衛．西格．伯恩斯坦(David Siegel Bernstein)在《科幻小說不是亂掰的: 白日夢世界中的真實科學》(Blockbuster science: the real science in science fic

Based on the mightily uplifting little book, Ishi: Simple Tips from a Solid Friend and its adorable Instagram account, @ishitherock, Ishi Postcards is a set of 30 postcards to send to someone in need

Easy-peasy recipes for first-time bakersWhen it comes to baking, even the littlest hands are eager to start mixing up tasty treats. Super Simple Baking for Kids equips new bakers with the most fun and easiest-ever recipes to whip up. Cookies, muffins, and cakes galore are sure to leave even grown-ups asking for more.Beginning with the basics, kids ages six to eight will learn key baking skills like how to separate eggs or knead dough. When these techniques are mastered, they can cook up over 55 super yummy recipes with confidence. (If only they were old enough to do the dishes!)This kids baking cookbook includes:Kids Baking tutorials—Kids learn all about equipment, safety, and skills they need to be successful in the kitchen.Easy as 1,2,3—Recipes use 5-10 ingredients max, no fancy equipment, and are labeled in degree of easiness.Fun foods—Making eating just as fun as baking with sweet and savory recipes like Rainbow Sprinkle Whoopie Pies, Apple-Cider Doughnut Cake, Soft Pretzels and mo

A colorfully illustrated, pocket-size picture book biography of famed artist Vincent van Gogh.Vincent van Gogh, one of the most important figures in Western art, is renowned for his Post-Impressionist

What if you threw your teacup out your window...and what if it accidentally knocked the moon out of the sky?A girl named Harriet longs to play her cello alone in her room. But when a noisy owl disrupt