Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Learn all about the fascinating world of insects--from bees, to butterflies, beetles, and more. Grab your magnifying glass and head out to discover all about insects-- their different types, body structures, and behaviors. Filled with eye-catching images and bite-sized information, every young nature enthusiast will marvel at the mind-boggling facts about these adaptable creatures. The book covers the seven major insect groups and includes profiles for more than 40 amazing insects, such as the stag beetle, monarch butterfly, and honeybee. Dive into their brilliant world and learn how some insects blend in with their surroundings. Discover how some can survive in different environments, while others can defend themselves against predators using clever tactics. Explore the many ways in which insects help humans, and the crucial role they play in pollination and maintaining a balance in the ecosystem. My Book of Bugs is a wonderful introduction to insects and their many incredible feature

Get your paints and canvases ready for a fun-filled journey through art! Explore how artists get ideas and bring them to life, how art can affect the way we think and feel, and why people throughout history loved it so much. Why is art important? What's so great about it? In this illustrated book, you'll see the world through famous artists' eyes, and what inspired them to make art. And you'll use their techniques to produce your own masterpieces. Did you know that early humans spent a great deal of time on their cave paintings? Before cameras and smartphones were invented, people had paintings and drawings made of them to keep a record of what they looked like. Many artists, such as Vincent Van Gogh and Frida Kahlo, used art as a language to express their feelings, thoughts, and emotions in ways that words couldn't. Explore techniques you can use to create art, and you don't have to be good at drawing and painting to do it. If you want to learn why art has the power to be beautiful, s

About MigrationsDiscover how the migration of peoples has shaped the modern world.This beautifully-illustrated book details the movement of people and cultures around the world - from the early migrations of Homo erectus out of Africa 50,000 years ago to modern refugee movements and migrations.Through striking photographs, evocative illustrations, and intimate first hand accounts, Migrations explores famous (and infamous) movements in history, from the Middle Passage and Trail of Tears to the California Gold Rush and the Windrush generation.While many traditional world histories focus on (mainly European) "exploration" and "discovery", Migrations explores the story of each continent and focuses on cultures rather than conquest. Migrations highlights the human story and the positives: what has survived, not just what was destroyed.With a foreword by award-winning historian, broadcaster, and filmmaker, David Olusoga OBE, Migrations is a history book with a fresh perspective, focusing on

Imagine learning to leap, roar, swim, or fly for the first time.Born to Be Wild explores the vast complexities of growing up in the animal kingdom, where everything feels like new. This book goes where no other has to delve into the countless ways baby animals survive in the wild. Alongside gorgeous photographs of baby bears, lions and tigers, marsupials, birds, and marine mammals, it charts the stages from dependency to independence, and looks at why some animals cling to their mothers for many months, while others must learn to run almost as soon as they are born.Informative step-by-step features focus on particular stages of learning, such as how a lion cub learns to hunt. This book focuses on key themes in a young animal’s life: birth and the very first days of life, learning to hunt and feed, senses and communication, habitat and adaptation, and playtime. Full of beautiful pictures and fascinating science, Born to Be Wild reveals the mysteries of how young creatures survive in an

Much more than a history atlas, this ?book drops you right in the heart of the action, as 130 detailed maps tell the story of pivotal episodes in world history, from the first human migrations out of

Grab your Spidey-Suit and explore the Spider-Verse in this first-ever LEGO® Marvel Spider-Man™ book!Discover a vast multiverse of spidery Super Heroes and their unique worlds in this fun and engaging guide to the world of LEGO Marvel Spider-Man. Learn about the vehicles and locations and meet amazing superstars like Peter Parker, Miles Morales and Gwen Stacy – as well as lesser-known characters like Pork Grind and Scarlet Spider.Swing into action with LEGO Spider-Man as you explore the Spider-Verse:Features LEGO sets based on the Marvel Comics and films, showcasing a range of fan-favourite Spider-Man characters, vehicles, and locationsExplore LEGO Spider-Man’s world, gadgets and suits as you find out more about the web-slinging hero and his friendsAdd to your LEGO collection with an exclusive Spider-Man minifigure insideA wonderful gift for younger kids who love LEGO, Spider-Man, or both!This entry point to the Spider-Man multiverse is the perfect gift for young fans eager to know more

A charming children's encyclopedia bursting with facts about the world, animals, people, planets, and so much more! My Encyclopedia of Very Important Things is a vibrant encyclopedia for curious 5-9 year olds, with a fresh approach to the subject that features both places from around the globe as well as focusing on what the world is like from a child's perspective, covering everyday subjects about their own experiences. Full of fun facts, colorful illustrations, and games that will keep the kids entertained time again, this children's encyclopedia is filled with age-appropriate knowledge on a range of terrific topics, from fiery volcanoes and our place in space, to changing seasons, mighty mammals and more. This children's encyclopedia about the world offers: - Educational content written in a friendly and fun manner. - Beautifully padded cover with several high-quality finishes, including padding and foil.- Features a built-in ribbon bookmark so you never lose your place whilst readi

本書專為7歲以上兒童設計，以圖像方式引導學習，讓新詞彙更容易掌握。書中以清晰、簡單的插圖呈現單字與片語，並依主題分區，如城市生活、運動、建築工地或餐廳點餐等日常情境。透過這些生活化的場景，孩子能直觀地理解詞義並應用於實際對話中。本書不僅是一部字典，更是延伸學習的工具，幫助孩子建立更廣的英文詞彙基礎，提升語言運用能力。亮點：圖像搭配詞彙，理解更直觀主題式分區，貼近生活情境適合7歲以上孩子循序學習幫助拓展英文詞彙量Learning new words is now easier for children aged 7+ with the Children's Visual Dictionary.This stunning new dictionary uses clear and simple illustrations to depict words and phrases in an engaging manner. Words are grouped into themed sections that cover practical, everyday topics - such as city life, sports, construction, or ordering food in a restaurant - helping young readers grasp complicated topics and build their knowledge of the English language. Children's Visual Dictionary helps young learners push the boundaries of their English vocabulary.

Get inside the machinery of the modern world and understand the science that makes it all work. Have you ever been tempted to take the back off your TV? Have you wondered about what's going on beneath your feet on the street where you live? How Technology Works lifts the lid on the technology you use all the time but take for granted. It also takes you to places you'll never get the chance to see, such as the inside of a nuclear storage facility or the crew capsule on top of a moon rocket. The book takes you on a journey of discovery, starting with technology at work inside the human body before exploring cities and factories and then blasting off into space. Along the way, you'll lose yourself in super-detailed illustrations that reveal amazing hidden things and explain how they work. How Technology Works is an inspiring guide that makes technology fun, fascinating, and accessible for curious minds of all ages.

Go on an amazing journey of discovery with the Very Hungry Caterpillar and learn about ocean wonders, from sharks to seamounts.Take a tour of the blue planet and discover everything you need to know about ocean geography and the animals that live beneath the waves.Topics range from individual sea creatures and their habitats, to how tides work and the ways in which we can look after the oceans. Bite-size chunks of information are complemented by captivating illustrations in Eric Carle's unique style, eye-catching photography, and simple how-it-works diagrams, while pull-out images and facts provide extra nuggets of interest. Young learners can find out all about marine mammals, deep sea fish, ocean zones, currents, islands, exploration, pollution, and much more in this one-of-a-kind introduction to oceans.For lovers ofThe Very Hungry Caterpillarand all bright young minds, this is the ultimate must-have oceans encyclopedia.

From Bolivia's bustling markets to the massive and scorching Sahara Desert, see the world with this beautifully illustrated atlas. Children's Illustrated World Atlas is divided into six main sections, each devoted to a continent. Within each continent, a country or a region is explored in detail through stunning maps showcasing cities, towns, rivers, mountain ranges, and other geographical features. Apart from the geography of a region, Children's Illustrated World Atlas also provides interesting information about the people, their traditions, politics, and economics through spectacular images and snippets of facts. Take a trip around the world with Children's Illustrated World Atlas, from the majestic Himalayas to the Carnival of Venice. This colorful and comprehensive book is the perfect addition to every book shelf at home or school.

Go on an amazing journey of discovery with the Very Hungry Caterpillar and learn fascinating facts about animals. Take a tour of the animal kingdom and discover everything you need to know about creatures from elephants to ants in this colorful and charming first animal reference book. Different chapters focus on different animal types, with a new critter every time you turn the page. Bite-size chunks of information are complemented by captivating illustrations by the World of Eric Carle, eye-catching photography, and simple how-it-works diagrams, while pull-out images and facts provide extra nuggets of interest. Young learners can find out all about koalas, armadillos, eagles, penguins, turtles, frogs, sharks, and butterflies and many, many more in this one-of-a-kind introduction to nature. For lovers of The Very Hungry Caterpillar and all bright young minds, this is the ultimate must-have animal encyclopedia.

This book is full of stories highlighting how philosophy over the ages has impacted the way we think and behave today. Travel down the road of wisdom to discover how philosophers have puzzled over the meaning of life, the human experience, and existence itself. Why is philosophy important? What's so great about it? Take a leap into the world of philosophy and have all your questions answered while discovering the unexpectedly interesting history of philosophy and its many schools of thought. Philosophical ideas affect our day-to-day lives in ways that you might not expect. But understanding these ideas can be daunting--even for adults! If you want to learn how to improve your thinking, make Aristotelian friends, visit Plato in his famous cave, or discuss women's rights with Mary Wollstonecraft, What's the Point of Philosophy? is the place to start. By telling interesting stories to unpack complex theories, What's the Point of Philosophy? allows you to connect with philosophers of the p

A comprehensive and accessible visual history of music – from prehistory to the present.Why did jazz go Latin? And how did blues influence rock? Find out how music has shaped the world from prehistory to the present.Classical or rock, everyone has their favorite music style, but how did your top choice come about? Music is a compelling and richly illustrated history of the most unifying art form in the world. Explore the roots of all genres, from chants of the middle ages through the grandeur of the classical period to the modern rhythm of blues, jazz, hip-hop, and pop. Music includes illustrated histories of instruments and listening suggestions for each musical genre. Spectacular galleries display families of instruments from around the world, while special features showcase the evolution of key instruments, such as the piano and the guitar, and profile iconic innovators such as Mozart, Billie Holiday, and David Bowie. Charting every musical revolution, from bone flutes to electronic

About Queen ElizabethAn official Platinum Jubilee souvenir that explores the incredible life and legacy of Queen Elizabeth and how her historic reign has shaped the world.In honour of Queen Elizabeth's Platinum Jubilee 2022, this once in a lifetime history book for kids tells the story of a young princess who grew up to become our longest reigning monarch, and celebrates the achievements, people and places that have become part of her remarkable legacy.There is a treasure box hidden away in Great Granny Joyce's home, bursting with all kinds of things... A photo of a young woman wearing a crown, a map of the world, newspaper clippings, and so much more that reveal the great wonders of the last 70 years. There is so much to look at that little Isabella doesn't even know where to begin! Did you know that Princess Elizabeth was only 27 when she became Queen? Or that she made an appearance at the opening ceremony of the 2010 London Olympics alongside James Bond? And that the most astonishin

How scientists changed the world, one breakthrough at a time. From the discovery of fire and the invention of the wheel to lunar landings and atoms, this book tells the extraordinary story of science and how it changed our world--one breakthrough at a time. Find out how history's most ingenious and daring scientists solved mysteries that had puzzled the ancient world for millennia, triggering an age of discovery that gave us telescopes, flying machines, steam engines, antibiotics, electricity, radio, space travel, and computers. Discover the amazing men and women who challenged conventional thinking and put their lives at risk to learn about everything from planetary orbits and gold to germs, gunpowder and radioactivity. What's the Point of Science? explains in super-simple terms how science really works and why it brought the world out of the dark ages. It's packed with surprising facts, tales of ingenuity and endeavor, and beautiful hand-drawn illustrations that bring the human story

You may not realize it, but math controls just about everything in our world.From cracking codes to winning game shows, from predicting comets to solving crimes, this unique book reveals where our mos

Stir up some sticky slime, build a Solar System with rubber bands, power a speed boat using soap, and construct an erupting volcano, all with Home Lab, exciting experiments for budding scientists. Inc

Trace India’s journey through its space program, from its early skywatchers, the myths and legends, and the dreamers in a newly independent country, to the visionaries who continue to inspire generations to look towards the stars.In 1947, a newly independent India struggled to manage its new borders, limited resources, and a burgeoning population. Almost instinctively, its leaders turned towards the skies, looking up and beyond to see how they could use technology and space to help their people. This wasn’t a new endeavour, however. Skywatchers in ancient India had always looked towards the stars, mapping them, giving them names, and building myths. So, new India turned towards the stars once again - using satellites to help with agriculture, forecast weather, and build better communication. Today, India’s space program has morphed into something larger. The country looks towards the stars―not to sustain itself, but to explore, to reach the final frontier, and to take its own place amo

Dive into our planet's largest and least explored world in this stunning encyclopedia of whales, waves, wrecks, wind farms, and everything oceanic!Using 3D illustrations and a level of detail you can'

Explore the laws and theories of physics in this accessible introduction to the forces that shape our Universe, our planet, and our everyday lives. Using a bold, graphic-led approach The Physics Boo

An exciting project-packed book of crafts, activities, and experiments for curious children who love to make, play, and explore. With clear step-by-step instructions and photos, children will learn ab

Full of hands-on activities that will tap straight into your child's natural scientific curiosity. The experiments are easy to follow and use items that most people already have tucked away at home.Lo

Discover how to identify flowers, where to find them, and other details about more than 100 flowers from around the world. Compact in size yet brimming with information, An Anthology of Flowers explores a vast variety of blooms, from exotic blossoms to iconic favorites. Learn to easily identify different species using detailed annotations, vivid illustrations, and unique descriptions of each flower. Featuring colorful photographs and vibrant illustrations, this book is a treasure trove for budding botanists, nature enthusiasts, and curious readers seeking an informative flower identification book. Whether you're out exploring or flipping through its pages at home, An Anthology of Flowers is sure to bring the natural world to life.

DK’s best-selling illustrated encyclopedia series explores the fantastical world of myths and legends. Discover stories from myth and legend as you've never seen them before through incredibly detailed 3D illustrations in this encyclopedia for children aged 9+. Knowledge Encyclopedia’s clear explanations, illustrations, photographs and 3D images will engage children in complex subjects.Find yourself transported to a realm of myth and legend with this perfect gift for anyone who loves stories of gods, monsters and heroes. This all-encompassing myth encyclopedia for kids offers:An impressive collection of facts, charts, timelines and illustrations. A visual approach using illustrations, photographs and extremely detailed 3D CGI images.Clear explanations and retellings of different myths and legends from around the world. Children can explore mythology in a new and exciting way through spectacular computer-generated images of key heroes, gods, monsters and locations. This new book in the

DK’s best-selling richly illustrated encyclopedia series explores the wonderful world of science. Learn the ins and outs of science as you’ve never seen it before, through incredibly detailed 3D illustrations, in this encyclopedia for children aged 9+. Knowledge Encyclopedia’s clear explanations, illustrations, photographs, and 3D images will engage children in complex subjects.This impressively detailed encyclopedia uses awesome illustrations to show biology, chemistry, and physics in the world around us. This all-encompassing science encyclopedia for kids offers:An impressive collection of facts, charts, timelines and illustrations. A visual approach using illustrations, photographs and extremely detailed 3D CGI images.Clear explanations of physics, chemistry, and biology, as well as space exploration, the latest technology, wonderful wildlife, and our amazing bodies. Children can explore science in a new and exciting way. Learn about groundbreaking topics like looking inside a cell,

DK’s best-selling richly illustrated encyclopedia series explores the wonderful world of transport. Knowledge Encyclopedia: Transport! uses incredibly detailed 3D illustrations to show children aged 9+ everything they need to know about how vehicles work. Children will find themselves totally absorbed in complex subjects with the Knowledge Encyclopedia series, made clear through engaging explanations, intricate illustrations, vivid photographs, and striking 3D images.Meet hundreds of vehicles that float, fly, or speed across the land, including the record breakers - the fastest, largest, longest, and strangest modes of transportation ever to zoom, sail, or soar. This all-encompassing encyclopedia for kids offers:- A whole collection of facts, charts, timelines, and illustrations that cover a vast range of transportation. - Complex subjects that are explained using amazingly detailed CGIs that entice young readers to dive in and explore.- A visual approach using illustrations, photograp

Discover the wonders of our rocky planet!This amazing deck of cards welcomes you to Earth's extraordinary minerals and gems, from sparkling emeralds to igneous rocks formed deep inside the Earth’s molten core. Stunning pictures and fast facts enable you to grasp a wealth of knowledge in a fun way. Each card contains snappy and accessible information, displaying each rock or mineral in dazzling detail. The front of the card shows the rock with a clue of what it is. The back reveals the answer, plus a dataset of essential information, ensuring you can recognize sedimentary from sandstone, metamorphic from marble, and pyrite from pearl. You’ll discover the unique qualities of each material, together with how it is used in art, industry, architecture, and science. You can use the cards to test your own knowledge, or how about using them to play a guessing game, quiz, or competitive comparison game with a friend? Our World in Pictures: Rocks & Minerals Flash Cards are packed with informat

Ideal for home learning, this simple and inspirational book has everything you need to get to grips with grammar and punctuation, and master essential reading and writing skills.Need help telling your adjectives from your adverbs? Struggling to work out what that poem is really about, or where to begin with your essay? Using short, straightforward explanations and clear graphics to shed light on the trickiest of topics, this is the perfect guide to understanding and using the English language.Illustrated examples make daunting grammar accessible and fun, and help develop an understanding that can be applied to school studies. Annotated texts complement concise, practical guidance to support students in developing sound analytical and writing skills. The carefully selected reading recommendations will inspire reading for pleasure, while clear links between topics will ensure that students not only understand language techniques but know how to apply them effectively.How to be Good at En

Imagine if you could travel back in time and walk the streets of the past. Where would you go first? Incredible History turns back time to reveal realistic reconstructions of the most incredible locations and exciting moments in history. You’ll feel the roar of the crowd in the Roman Colosseum, walk the ramparts of the Great Wall of China, and ride the first railways. Each story begins with an archaeological site or artifact. You’ll learn when and how it was discovered, and what it teaches us about how the people who lived at the site might have spent their days. Then, you’ll see the location recreated in jaw-dropping 3D detail. Using archaeological evidence, the people and places of the past will be brought back to life before your very eyes. With each page packed with fantastic facts and extraordinary pictures, Incredible History brings together the best parts of history and archaeology to recreate the entire history of the world.

How did they make that using LEGO® bricks?Find out! Meet the professional builders behind some amazing LEGO® models and learn all about how these creative experts make masterpieces using LEGO bricks.

See how young animals grow and change in the first weeks and months of their lives with this series of animal books for young nature lovers. Everyone loves little animals and this book is a must for fans of cute pets. This elegant book follows baby animals in beautiful, crisp photography through their early lives--from helpless newborns to confident, curious creatures on the cusp of adulthood. Meet a playful puppy, a curious kitten, and a delightful baby rabbit and watch how they grow. A series of photographs shows each animal at different stages in its early life. See a bunny before it grows fur, kittens learn to hunt, and a puppy play with toys. These books are a delight to read aloud to preschool children or for young readers to pick up themselves. A must for all young fans of animals.

Discover the rich and complex history of the peoples of Africa, and the struggles and triumphs of Black cultures and communities around the world. With profiles of key people, movements, and events, The Black History Book brings together accounts of the most significant ideas and milestones in Black history and culture. This vital and thought-provoking book presents a bold and accessible overview of the history of the African continent and its peoples - from the earliest human migrations to modern Black communities and the African diaspora. Powerful images and innovative infographics bring to life the stories of the early kingdoms of Ancient Egypt, Nubia, and Carthage; the powerful empires of the Medieval and Early Modern eras; and the struggle against European colonizers. Black history and culture beyond the African continent is also explored in detail - including the Atlantic Slave Trade; the quilombos (slave resistance camps) of Brazil; the Harlem Renaissance and Jazz Age; the "Wind

The simplest guide to astronomy and stargazing!Grasping astronomy has never been easier. The awe of the night sky will soon turn into knowledge of the constellations, planets, and astrological phenomena!Bold graphics and easy-to-understand text make this visual guide the perfect introduction to astronomy and stargazing for those who have little time but a big thirst for knowledge. Inside you'll find:- Simple, easy-to-understand graphics that help to explain astronomy, space, and the night sky in a clear, visual way- The latest astronomical information on black holes, gravitational waves, the origin of the Universe, and the planets of the Solar System- User-friendly star-charts that guide you through the sky using brighter stars as "signposts" to locate harder-to-see objects- Essential advice on the practicalities of stargazing - from observing with the naked eye to using telescopesEach pared-back entry covers the essentials more clearly than ever before.

Explore the magic of holidays at Hogwarts Features Harry Potter minifigure in Yule Ball robes. Enter the festive world of LEGO(R) Harry Potter(TM) and visit Hogwarts for a spellbinding winter holiday. Celebrate the season with your favorite LEGO Harry Potter minifigures and join them for a feast in the Great Hall. Admire the castle's decorations and get ready to hit the dance floor at the Yule Ball. Head to the Gryffindor common room to play a game of wizard chess, warm up in front of a roaring log fire, and join Harry as he exchanges gifts with friends. Sprinkled with festive scenes and the latest LEGO Advent Calendars, sets, and minifigures, this is the perfect gift for young LEGO Harry Potter fans. LEGO Harry Potter: Holidays At Hogwarts comes with a Harry Potter minifigure in Yule Ball robes. (c) & (TM) Warner Bros. Entertainment Inc. Publishing Rights (c) JKR. (s20). (c)2020 The LEGO Group.

This picture word book of 1000 first science words is the perfect STEM book for helping children learn.This book introduces key scientific concepts while broadening children's vocabulary and strengthening their early reading and writing skills. Every picture-packed page is full of things such as sounds, light, senses, and machines, with words for each image. 1000 Words: Science clearly labels each picture, which encourages picture-and-word association and helps early reading. Each topic features questions that ask children to find things on the page or that stimulate thinking, talking, and early science skills. The words have been chosen with the help of a leading educational consultant, and include lots of useful nouns, plus some interesting adjectives, and common verbs. This fun and educational picture word book is a must-have first reference title for parents who are keen to develop their child's language, science, and literacy skills.

Journey back in time and find out where dinosaurs roamed. This unique children's atlas explores each continent, revealing fossil sites and stories on every map. This atlas is packed with maps of early

Get set for a journey across the globe, visiting every country - from Afghanistan to Zimbabwe - to find out what makes each one unique. Along the way, you'll explore mountains, deserts, forests, and r

This book empowers children by providing an affirmation for every single day of the year from January 1 to December 31.I am strong. I am brave. I can handle anything. Using the power of positive think

Take an exclusive backstage tour of the world's most exciting museums and discover their hidden treasures.This behind-the-scenes guide showcases a huge range of incredible artifacts from history and r