Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Power up with this full-color leveled reader based on The Super Mario Galaxy Movie—in theaters April 1, 2026!Mario takes off on an out-of-this-world adventure with Luigi, Princess Peach, and all their friends in an all-new movie. Children and Mario fans of all ages will love this full-color level reader based on The Super Mario Galaxy Movie—in theaters April 1, 2026!

Here we go! Keep the pedal to the metal with Mario, Luigi and all their friends in this Mario Kart™ Step into Reading level reader!Nintendo and Mario Kart™ fans ages 5-8 will love to meet Mario, Luigi, and all their friends and foes in this Step 3 Step into Reading level reader as they compete and race to win! Step 3 readers feature engaging characters in easy-to-follow plots about popular topics. For children who are ready to read on their own.

Cross lava caves, enchant armor, and travel into the Nether and beyond with the Official Minecraft Workbook for 2nd Grade! Includes 100+ colorful reward stickers.Pick up your pencils and get ready to learn with creepers, piglins, Endermen, and more—in the Official Minecraft Workbook series! With playful, game-based reading and math exercises, inventive end-of-lesson Minecraft Missions, reward stickers, and a fun completion certificate, second graders will practice and reinforce key classroom concepts including:sight wordsspelling and vocabularydecoding wordsexploring numbers and valuesmulti-digit addition and subtractionparts of speech and reading... and more!

Journey through Minecraft biomes, outsmart hostile mobs, and craft your way through this official Minecraft Activity Book! Includes over 200 stickers, puzzles, mazes, and so much more! Fans of all ages will love encountering mobs and exploring biomes while completing the codes, scrambles, mazes, sequences, sticker activities, and more in this Minecraft Official Activity Book. With full-color pages and over 200 stickers, it's hours of fun for Minecraft fans ages 6 to 9 and a whole new way to experience and expand on the best-selling video game of all time! (c) 2024 Mojang AB. All Rights Reserved. Minecraft, the Minecraft logo, the Mojang Studios logo and the Creeper logo are trademarks of the Microsoft group of companies.

本書內含64張著色圖、16種水彩顏色與專屬畫筆，打開就能開始創作。從熟悉的角色到經典場景，每一頁都是一個小關卡，讓孩子在塗色過程中培養專注力與美感。Super Mario™ fans will love this all-new Super Mario Deluxe Paint Box Book featuring 64 images to paint, a paintbrush, and 16 different watercolors!Children ages 3 to 7 will love to paint Mario, Peach, Bowser, and all their favorite friends and enemies from the Mushroom Kingdom in this Super Mario™ Deluxe Paint Box Book featuring 64 images to paint, a paintbrush, and 16 different watercolors. Yippee!Mario first appeared in 1981 with the arcade classic Donkey Kong, and has since gone on to star in many adventures. He is a video-game sensation, ready for new challenges with his friends by his side.

The action-packed world of LEGO(R) NINJAGO(R) Spinjitzu comes to life in this illustrated chapter book featuring Wu and Garmadon in their early adventures on the road to becoming Spinjitzu Masters! Wu and Garmadon both want to become Spinjitzu Masters--but there are many who stand in their way--especially each other. As the LEGO(R) ninja brothers travel the land, they face epic tests to see if they have what it takes to gain the skills they need to become true legends of Spinjitzu! This illustrated hardcover chapter book series features the LEGO(R) NINJAGO's Spinjitzu Brothers and exciting illustrations! LEGO, the LEGO logo, the Brick and Knob configurations, the Minifigure and NINJAGO are trademarks and/or copyrights of the LEGO Group. (c)2022 The LEGO Group. All rights reserved.

The action-packed world of LEGO(R) Ninjago(R) Spinjitzu comes to life in this illustrated chapter book series featuring Wu and Garmadon in their early adventures on the road to becoming Spinjitzu Masters! Wu and Garmadon both want to become Spinjitzu Masters--but there are many who stand in his way--especially each other. Will their adventures bring them closer together or prove to be their undoing? And more importantly, do they have what it takes to gain all the skills they need to become true legends Spinjitzu? Find out in Book 3 of this all-new illustrated chapter book series featuring the LEGO Ninjago's Spinjitzu Brothers!

This hardcover collection contains 9 action-packed LEGO City(R) stories that can each be read aloud in about five minutes. With a sturdy padded cover, LEGO City(R) fans ages 3 to 7 will read all about their favorite characters in this LEGO City(R) 5-Minute Stories hardcover collection of nine action packed tales--all of which can be read in five minutes or less. LEGO, the LEGO logo, the Brick and Knob configurations, the Minifigure and NINJAGO are trademarks of the LEGO Group. (c)2023 The LEGO Group. Manufactured by AMEET Sp. z o.o. under license from the LEGO Group.

This hardcover collection contains 9 action-packed tales of the LEGO(R) NINJAGO(R) warriors that can be read aloud in about five minutes. With a sturdy padded cover, LEGO(R) NINJAGO(R) fans ages 3 to 7 will read all about their favorite characters as they master their skills in this LEGO NINJAGO 5-Minute Stories hardcover collection of ten action packed tales--all of which can be read in five minutes or less. Perfect for bedtime--or anytime

Join in a super-silly Christmas celebration based on an all-new LEGO(R) holiday song!The holiday season can get a little kooky--especially when LEGO(R) friends come to visit. Get ready for Christmas w

Enter the creative worlds of LEGO(R) and Minecraft(R) with this Seek & Find activity book featuring stickers and a LEGO minifigure with accessory! Find out what happens when a LEGO(R) Minecraft(R) TBD goes on an action and activity packed adventure! This LEGO Minecraft Search and Find activity book features photos of real LEGO sets in busy scenes filled with fun details and objects to find--plus mazes, seek and find activities and more! Some activities are solved with the included stickers which add to the fun and adventure. And most awesome of all, this book features a LEGO Minecraft Skeleton minifigure wearing a helmet and carrying a bow and arrow!LEGO, the LEGO logo and the Minifigure are trademarks and/or copyrights of the LEGO Group. (c)2025 The LEGO Group. All rights reserved.(c) 2025 Mojang AB. All Rights Reserved. Minecraft, the Minecraft logo, the Mojang Studios logo and the Creeper logo are trademarks of the Microsoft group of companies.

An all-new storybook about the LEGO(R) City firefighters--plus 30 brick-tastic stickers!Children 3 to 7 will love to read about their favorite LEGO(R) City firefighters as they learn what it means to be everyday heroes as they practice new skills and try out new equipment in this full-color storybook--plus 30 brick-tastic stickers!LEGO City delivers reality-based role-play and building fun. LEGO City is all about REAL action, REAL fun, and REAL heroes. It can be seen on Nickelodeon, Netflix, and Amazon.

Phonics readers are in demand! Research shows that early phonics instruction is a key to reading success. With Set 2, kids will take the next step, practice decoding, and build on the skills they developed in Set 1.Developed by a phonics expert,Phonics First Stepsare an innovative program designed to help kids learn to read, step by step. New and improved—our bright boxed sets include eight little easy-to-decode books (24 page each), now illustrated in full-color, with an easier to read font for emergent readers—plus a handy parent guide. Children will gainconfidence each time they say, "I read this book!"Set 2 covers short vowels, blends, digraphs, and more!

A collection of nine PAW Patrol stories that focus on kindness and teamwork. Each story can be read in five minutes or less, so it's perfect for bedtime--or anytime! Chase, Skye, Marshall, and the rest of Nickelodeon's PAW Patrol are always already to lend a helping paw to a friend in need. Join them as they help an itchy monkey, calm a worried friend, and help someone to the doctor's office. These are just a few of the nine tales that celebrate helping, kindness, and serving your community in this hardcover collection of stories that can each be read aloud in five minutes or less. Nickelodeon fans ages 3 to 7 will love these stories that are perfect for bedtime or anytime. Get on the case with Nickelodeon's PAW Patrol! Chase, Marshall, Rubble, Skye, and the rest of the puppy heroes are always read to save their friends and protect the community of Adventure Bay using their PAWsome vehicles, tools, and teamwork.

This all-new hardcover collection features nine LEGO(R) Jurassic World stories that can each be read aloud in about five minutes. With a sturdy padded cover, this LEGO Jurassic World Lego 5-Minute Stories collection makes wrangling dinosaurs with Owen Grady fun! Boys and girls ages 3 to 7 will love this collection of nine stories that are packed with action and humor--and feature T. rex, Blue the velociraptor, and all their other favorite Lego Jurassic World dinosaurs. Each story can be read in about five minutes or less, so it's perfect for bedtime--or anytime!

Dinosaurs, action-packed adventure and laugh-out-loud fun fill this all-new LEGO(R) Jurassic World(TM) chapter book series! From small, quick dinosaurs on the loose to the big T. rex causing trouble to a boss who loves surprises, Owen, Claire, and the bumbling Asset Containment Unit have their hands full keeping all the dinosaurs and guests at Jurassic World safe. With action-packed illustrations throughout, this engaging chapter book features three fun-filled stories that are perfect for LEGO(R) Jurassic World(TM) fans and kids ages 6 to 9 who love dinosaurs. Look out for these other great books: - LEGO(R) Jurassic World(TM) Daring Dinosaur Adventures!- Untold Dinosaur Tales #1: Dangerous Eggs-pedition! (LEGO Jurassic World) (c) 2022 The LEGO Group and Universal City Studios LLC and Amblin Entertainment, Inc. Series (c) 2022 DreamWorks Animation LLC. All Rights Reserved. LEGO, the LEGO logo, the Brick and Knob configurations and the Minifigure are trademarks of the LEGO Group.

Danger, dinosaurs, and laugh-out-loud fun fill this all-new LEGO(R) Jurassic World(TM) chapter book series! From baby dinosaurs on the loose to the big T. rex causing trouble, Owen, Claire, and the bumbling Asset Containment Unit have their hands full keeping all the dinosaurs and guests at Jurassic World safe. With action-packed illustrations throughout, this engaging chapter book features three fun-filled stories that are perfect for LEGO(R) Jurassic World(TM) fans and kids ages 6 to 9 who love dinosaurs. Look out for these other great books: - LEGO(R) Jurassic World(TM) Daring Dinosaur Adventures! (c)2022 The LEGO Group and Universal City Studios LLC and Amblin Entertainment, Inc. All rights reserved. LEGO, the LEGO logo, the Brick and Knob configurations and the Minifigure are trademarks and/or copyrights of the LEGO Group.

Step into the action-packed world of LEGO(R) NINJAGO(R) Spinjitzu and learn everything there is to know about mastering the art of Spinjitzu in the ancient full-color tome known as The Book of Elementals Do you have what it takes to become a Spinjitzu Master? If you think so, The Book of Elementals is packed with all the knowledge you will need to master all the elements and become a ninja hero . . . or perhaps villain This full-color book features big glossy pages with art and exciting information about the world of LEGO NINJAGO LEGO, the LEGO logo, the Brick and Knob configurations, the Minifigure and NINJAGO are trademarks of the LEGO Group. (c)2021 The LEGO Group.Manufactured by AMEET Sp. z o.o. under license from the LEGO Group.

An awesome Batman (TM) activity book packed with over 500 stickers!Swing into the crime-fighting world of Batman with this awesome full-color activity book that features over 500 stickers of Batman, R

Inspired by the work of Dr. Seuss, the 5 books in this collection feature simple reading and math activities that make early learning FUN--and FUNNY! With over 100 stickers, it's the perfect way for c

A brand-new train-shaped Thomas board book!This sturdy train-shaped board book lets train-loving boys and girls ages 0 to 3 learn all about their favorite blue engine, Thomas!In the early 1940s, a lov

An official graphic novel retelling of Netflix's KPop Demon Hunters with full-color scenes and dialogue from the movie! When K-pop superstars Rumi, Mira, and Zoey aren't selling out stadiums, they protect the world from demons with their musical abilities. Follow their band HUNTR/X, as they make music and face their greatest challenge yet--Saja Boys, the hottest new boy band with a dark secret. This official paperback graphic novel retells Netflix's KPop Demon Hunters using full-color images and dialogue from the hit movie. Based on the screenplay by Danya Jimenez & Hannah McMechan and Maggie Kang and Chris AppelhansBased on KPop Demon Hunters, the film Directed by Maggie Kang and Chris Appelhans

Your child has cracked the code of letters and sounds and is ready for more! Research shows that early phonics instruction is a key to reading success. With Phonics First Steps boxed sets, kids will practice decoding and build on skills they develop with each book in the 8-book set!Children will gainconfidence each time they say, "I read this book!"Developed by a phonics expert,Phonics First Stepsare an innovative program designed to help kids learn to read, step by step. New and improved—our bright boxed sets include eight little easy-to-decode books (24 pages each), now illustrated infull-color, with an easier to read font for emergent readers—plus a handy parent guide to walk you through how to use these books with your reader.Set 3 covers short vowels, blends, digraphs, and more!

Build a house, tame a wolf, and help save the village and more with the Official Minecraft Workbook for Kindergarten! Includes 100+ colorful reward stickers.Pick up your pencils and get ready to learn with villagers, creepers, and more—in the Official Minecraft Workbook series!With playful, game-based reading and math exercises, inventive end-of-lesson Minecraft Missions, reward stickers, and a fun completion certificate, kindergarteners will practice and reinforce key classroom concepts such as:*exploring the alphabet*counting and identifying numbers*short vowels*early addition and subtraction*shapes, colors, and patterns*beginning phonics... and more!Friendly and fun, this workbook is a perfect fit for Minecraft fans and reluctant learners ages 5-6.Also available: Official Minecraft Workbooks for Grade 1, Grade 2, and Grade 3© 2024 Mojang AB. All Rights Reserved. Minecraft, the Minecraft logo, the Mojang Studios logo and the Creeper logo are trademarks of the Microsoft group of compa

The Batman(TM) The Deluxe Junior Novel--Special Edition combines fast-paced prequel story with exciting events from the all-new motion picture The Batman, which swings into theaters in theaters on March 4, 2022! Warner Bros.'s The Batman releases in theaters March 4, 2022, bringing with it all the adventure and action of one of the most popular Super Heroes in the world. We all know that billionaire Bruce Wayne is secretly Gotham City's vigilante detective and protector, The Batman--but what road led him there? Find out in The Batman: The Deluxe Junior Novel--Special Edition, which includes the exciting prequel story of Bruce Wayne's early adventures on his way to becoming The Batman, as well how those events come to an exciting conclusion in the new action-packed feature film, starring Robert Pattinson as Batman and Zo?Kravitz as Catwoman. This novel features an eight-page full-color insert and a pull-out poster!

Get Ready Books teach valuable life lessons with your favorite Nickelodeon characters--and they include over 30 stickers!Marshall learns that even heroic pups get scared. Luckily, Nickelodeon's PAW Patrol is there to support him and help him deal with his fears. Boys and girls ages 3 to 7 will enjoy this storybook that shows children how they can cope with nervousness and worries. Featuring popular Nickelodeon characters and fun-filled stories, Get Ready Books teach important social-emotional lessons. Look for the second book in the series, SpongeBob Goes to the Doctor. Follow Nickelodeon's PAW Patrol! Chase, Marshall, Rubble, Skye, and the rest of the puppy heroes are on missions to save their friends and protect the community of Adventure Bay using paw-some vehicles, tools, and teamwork.

Four amazing adventures in one action-packed book featuring Spider-Man and his friends from the Avengers as well as his friend Ghost-Spider! Perfect for fans of Marvel Super Heroes. Marvel fans will love this full-color storybook featuring four stories in one. First, Nick Fury gets more than he bargained for when a new device turns Spider-Man and the Hulk into one incrediblely hungry Super Hero. Then swing into fun with Spider-Man as the web-spinning Super Hero saves the day again and again in three other adventures featuring Ghost-Spider, the small-but-mighty Ant-Man, and the Avengers. This exciting storybook is perfect for young fans of these iconic characters.

跟電影有關的著色、迷宮、字謎等活動。Power up with this full-color, action-packed activity book based on Nintendo and Illumination present The Super Mario Bros. Movie—in theaters April 7, 2023!From Nintendo and Illumination comes a new animated film based on the world of Super Mario Bros. Featuring Mario, Luigi, and Princess Peach, boys and girls ages 3 to 7 will love this coloring-and-activity book with full-color mazes, word searches, and other engaging activities inspired by the film—including removable cardstock characters and a background for a fun-filled playset!Series Overview: We will publish a small movie tie-in program including a POB hardcover storybook, a Step into Reading, and full-color activity book in Spring 2023, and a Pictureback 8x8 in Summer 2023.We also have a full line of best-selling non-movie Mario and Nintendo C&A and storybooks. 開箱影片 https://www.youtube.com/watch?v=usxFabrgHSE適讀年齡 3-7歲

A board book based on The Cat in the Hat--perfect for introducing Dr. Seuss's most beloved characters to babies and toddlers! The Cat in the Hat introduces himself, Thing One and Thing Two, and Little Cats A-Z in this simple, sturdy board book about the joy of having fun. Written in rhymed verse, it's an ideal introduction to the characters for children too young for the Beginner Books The Cat in the Hat and The Cat in the Hat Comes Back. Now everyone in the family--even pre-readers--can get to know (and love) the Cat in the Hat!

Meet all your L.O.L. Surprise! fierce friends in this all-new Step 3 Step into Reading reader--with more than 30 sweet and sassy stickers! This Step 3 Step into Reading leveled reader has over 30 outrageous L.O.L. Surprise! stickers--perfect for boys and girls ages 5 to 8! Step 3 readers feature engaging characters in easy-to-follow plots about popular topics. For children who are ready to read on their own. In a world where babies run everything, little Rockers rebel against nap time and Teacher's Pets become class presidents with Free Pizza Fridays! In the L.O.L. Surprise! world, all work is play and nothing is dull cuz it's all a lil' surprising and outrageous!

An action-packed retelling of Avatar: The Last Airbender with full-color scenes and dialogue from the series. . . Screen Comix style The mysterious origins of Aang, the Avatar and last Airbender, are retold in the new Screen Comix format Based on the epic Nickelodeon series, this first book reveals how Aang emerges from a hundred years frozen in an iceberg to find the world is very different from the one he once knew. With the help of a waterbender named Katara and her brother Sokka, Aang searches for teachers to help him master his skills and escape Prince Zuko in order to end the Fire Nation's war and bring balance to the world. The stakes couldn't be higher in this 320-page full-color retelling of the first six episodes of the show, featuring final frames and dialogue from the series. This book will delight Avatar fans of all ages.

A fun-filled collection of stories starring Dr. Seuss’s Cat in the Hat that can each be read aloud in five minutes!Nick and Sally have questions about everything from trees to outer space. Luckily, th

Each of the nine stories in this collection feature favorite Nickelodeon girl characters and can be read aloud in five minutes!Join your favorite Nickelodeon girls in nine exciting stories! Readers ag

Celebrate the holiday season with Blue in this adorable board book based on Nickelodeon’s Blue’s Clues and You!Join Josh in a special winter game of Blue’s Clues in this festive story featuring favori

Two exciting Disney Princess stories in one book!Mulan from Disney Mulan competes in a Dragon Boat Race, and Princess Cinderella from Disney Cinderella helps a new friend find her voice in this deluxe

Discover all the joys of Halloween with Baby Cat in the Hat, Baby Grinch, Baby Lorax, and more of the Dr. Seuss Babies! This adorable book features chunky easy-to-lift flaps, perfect for little hands! Nurture a love of reading and of Dr. Seuss! Babies and toddlers will love to learn about Halloween traditions with their favorite Dr. Seuss Babies characters! Lift the flaps to reveal funny Halloween costumes, a pumpkin turning into a jack-o'-lantern, and other delightful tricks and treats in this interactive board book featuring simple rhyme. Look for more Dr. Seuss Babies titles: Happy First Birthday with Dr. Seuss BabiesMerry Grinchmas, Baby! with Dr. Seuss BabiesMr. Brown on the Farm with Dr. Seuss BabiesGood Night, Baby! with Dr. Seuss Babies

★ 電影改編繪本，碧姬公主生日派對大事件！★ 全彩精裝，最適合親子共讀的瑪利歐故事★ 溫馨派對×神祕訪客，冒險即將展開蘑菇王國最重要的一天來了——碧姬公主的生日！瑪利歐、路易吉與所有朋友都準備好盛大慶祝，派對氣氛熱鬧又歡樂。然而，就在大家沉浸於歡笑時，一位神祕訪客突然現身，讓這場生日派對出現意想不到的變化……這場原本溫馨的慶生會，會變成一場新的冒險嗎？Join Mario and his friends for Princess Peach’s birthday in this hardcover picture book based onThe Super Mario Galaxy Movie—in theaters April 1, 2026!Mario and everyone in the Mushroom Kingdom are ready to celebrate Princess Peach’s birthday, but events take an unexpected turn with the arrival of a mysterious visitor. Children and Mario fans of all ages will love this full-color hardcover picture book based onThe Super Mario Galaxy Movie—in theaters April 1, 2026!

★ 電影同步登場！《瑪利歐銀河冒險》活動書★ 100張貼紙＋多元任務，挑戰全面升級★ 一起進入宇宙關卡，Power Up！準備好飛向宇宙了嗎？跟著瑪利歐、路易吉與夥伴們，進入全新銀河世界！這次的冒險不只在大銀幕，更延伸到你的手中——迷宮、找找看、解謎任務，搭配100張貼紙，讓每一頁都像在闖關。讓孩子在遊戲中培養觀察力與專注力，是瑪利歐粉絲不可錯過的精彩讀物。Power up with this full-color, action-packed activity book based onThe Super Mario Galaxy Movie—in theaters April 1, 2026!A full-color activity book with 100 stickers based onThe Super Mario Galaxy Movie—in theaters April 1, 2026!

Fans of Netflix's Stranger Things will love this full-color activity book that's filled with puzzles, codes, and trivia. How well do you know Hawkins, its residents, and all its unusual history? Packed with full-color pictures from Netflix's iconic show Stranger Things, this activity book includes trivia, puzzles, and codes that are sure to challenge and entertain kids 7 to 10--and fans of all ages. Welcome to the thrilling world of Netflix's hit series Stranger Things. Follow Eleven, Dustin, Max, Lucas, and their friends for mystery, suspense, and supernatural adventures in 1980s Hawkins.