Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Artificial intelligence (AI) stands out as a transformational technology of the digital age. Its practical applications are growing very rapidly. One of the chief reasons AI applications are attaining prominence, is in its design to learn continuously, from real-world use and experience, and its capability to improve its performance.It is no wonder that the applications of AI span from complex high-technology equipment manufacturing to personalized exclusive recommendations to end-users. Many deployments of AI software, given its continuous learning need, require computation platforms that are resource intense, and have sustained connectivity and perpetual power through central electrical grid. In order to harvest the benefits of AI revolution to all of humanity, traditional AI software development paradigms must be upgraded to function effectively in environments that have resource constraints, small form factor computational devices with limited power, devices with intermittent or no

Solution-Focused Play Therapy is an essential text that blends the process of play therapy with solution-focused therapy. With a focus on child strengths and resources, this book identifies key concepts and principles in solution-focused play therapy (SFPT). The author provides neurobiological and developmental support for SFPT and guidance on how practitioners can transition from using a non-directive approach to a more directive and activity-based approach based on the developmental needs of the child.Chapters describe the 12 basic skills needed for employing this approach with children of all ages and their families. Harnessing a strengths-oriented approach, the author presents expressive ways to use key SFPT techniques, including the miracle question, scaling, finding exceptions, and end-of-session feedback. Clinicians will come away from the book with a suite of interventions, strategies, handouts, and forms that can be employed with children of all ages and their families, from s

The key focus of the book is on engineering aspects of the subject fieldUpdated, comprehensive text covering offshore drilling, production and field development and offers complete coverage of offshore oil and gas operations. Also, key maintenance issues like pigging, corrosion, subsidence are discussed.

The seventh edition of the highly successful The City Reader juxtaposes the very best classic and contemporary writings on the city. Sixty-three selections are included: forty-five from the sixth edition and eighteen new selections, including three newly written exclusively for The City Reader. The anthology features a Prologue essay on "How to Study Cities", eight part introductions as well as individual introductions to each of the selected articles. The new edition has been extensively updated and expanded to reflect the latest thinking in each of the disciplinary and topical areas included, such as sustainable urban development, globalization, the impact of technology on cities, resilient cities, and urban theory. The seventh edition places greater emphasis on cities in the developing world, the global city system, and the future of cities in the digital transformation age. While retaining classic writings from authors such as Lewis Mumford, Jane Jacobs, and Louis Wirth, this editi