Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

This successor volume to The Hidden Origins of Islam (edited by Karl-Heinz Ohlig and Gerd-R. Puin) continues the pioneering research begun in the first volume into the earliest development of Islam. U

This graphic novel adaptation contains more than fifty pages of exclusive content not available in the original comic books, including‧ a new Preface by George R. R. Martin‧ early renderings of key sc

In a handful of years between the development of electrical recording in 1925 and the outset of the Great Depression in the early 1930s, the soundscape of modern music unfolded in a series of relative

A hands-on science book packed with fun experiments from rockstar science educator Carmelo the Science Fellow! Designed to encourage kids' natural love of science from an early age, this book promotes

A unique approach to the history of science using do-it-yourself experiments along with brief historical profiles to demonstrate how the ancient alchemists stumbled upon the science of chemistry.Be th

A stand-alone entry in the Shannara series finds Paxon Leah attempting to rescue his kidnapped sister using a seemingly insignificant family sword only to uncover a plot to overthrow the Druids, who r

Developed in Japan in the early 1990s, metal clay represents a dramatic development in the handling of precious metals for jewelrymaking. Metal clay consists of microscopic particles of silver or gold

This is a no-holds-barred response to the liberal and conservative retreat from an assertive, activist, and socially transformative civil rights agenda of recent years--using a black feminist lens and

A New York Times BestsellerAn audacious, irreverent investigation of human behavior—and a first look at a revolution in the makingOur personal data has been used to spy on us, hire and fire us, and sell us stuff we don’t need. InDataclysm, Christian Rudder uses it to show us who we truly are. For centuries, we’ve relied on polling or small-scale lab experiments to study human behavior. Today, a new approach is possible. As we live more of our lives online, researchers can finally observe us directly, in vast numbers, and without filters. Data scientists have become the new demographers.In this daring and original book, Rudder explains how Facebook "likes" can predict, with surprising accuracy, a person’s sexual orientation and even intelligence; how attractive women receive exponentially more interview requests; and why you must have haters to be hot. He charts the rise and fall of America’s most reviled word through Google Search and examines the new dynamics of coll

The Mindful Mother offers you unparalleled support and nurturing throughout pregnancy, labour and early motherhood. Author Naomi Chunilal shows you how clear and simple meditation and self-development

Drawing from five years' worth of investigative reporting, presents the history of Latin American drug cartels, revealing how Mexico became their base and the extent of corruption within the country's

Break through writer's block using your five senses!The sensory details that infuse our everyday experience—the smell of a favorite dish cooking, the texture of a well-worn coat, hearing a song that r

Entheogens and the Development of Culture makes the radical proposition that mind-altering substances have played a major part not only in cultural development but also in human brain development. Res

In this joyous and whimsical holiday novel, Debbie Macomber rings in the season with the return of Shirley, Goodness, and Mercy, delivering laughs, love, and a charming dose of angelic intervention.

What happens when two cartoonists for The New Yorker fall in love and marry? Lots of witty wordplay, skewering drawings, and a healthy dose of illustrative competition. For twenty years, veteran carto

The Cassel sisters have little in common besides a pair of wacky parents and a maddening knack for eluding happily-ever-after endings. But when their lives require damage control, only a dose of siste

Using both canonical and noncanonical primary texts, Ludemann (history and literature of early Christianity, U. of Gottingen) presents evidence that the resurrection was not a historical event and arg

Millions of people already live their lives in accordance with Rob Brezsny's "Real Astrology" prophecies. But the time has come for a deeper dose of Brezsny's brain. The Televisionary Oracle is an arc

SOON TO BE A NETFLIX LIMITED SERIES. The origin of the opioid epidemic from the Pulitzer Prize-winning journalist who first broke the story: A searing account of this country's greatest health crisis that implicates OxyContin's maker and the U.S. governmentBetween 1999 and 2017, an estimated 250,000 Americans died from overdoses involving prescription painkillers, a plague ignited by the aggressive marketing of OxyContin by its maker, Purdue Pharma. Purdue, owned by a wealthy and secretive family--the Sacklers--knew early on that teenagers and others were abusing its billion dollar "wonder" drug. But Justice Department officials balked a decade ago when it came to meting out justice, allowing an opioid crisis to evolve into a catastrophe. Meier reveals new and shocking information about how long the drug maker knew about OxyContin's abuse, even as it marketed it aggressively, and the way government officials passed up opportunities to protect tens of thousands of lives. Equal

Yoga has never been more popular. Throughout the United States, people are turning to this ancient practice as a response to the pressures of today’s hectic world. In Meditations on Intention

The early fiction of one of the nation’s most celebrated writers, Truman Capote, as he takes his first bold steps into the canon of American literatureRecently discovered as manuscript pages in the ar

From the twisted imagination of creator Michael Dougherty (director of the upcomingKrampus and Trick ‘r Treat, screenwriter of X-Men 2 and Superman Returns) and a top-notch team of artists includingFi

New York Times bestselling author Joe Abercrombie’s thrilling new series continues in the follow-up toHalf a King, which George R. R. Martin hailed as “a fast-paced tale of betrayal and revenge that g

In the grand tradition of George R. R. Martin, Terry Brooks, David Eddings, and Robert Jordan, New York Times bestselling author Peter V. Brett continues his critically acclaimed Demon Cycle, which la

Joe Abercrombie’s Best Served Cold meets George R. R. Martin’s A Game of Thrones in the final novel in Richard K. Morgan’s epic A Land Fit for Heroes trilogy, which burst onto the fantasy scene with T

"Richard McGuire's Here is the story of a corner of a room and the events that happened in that space while moving forward and backward in time. The book experiments with formal properties of comics,

Drawing on both their own fieldwork from 1991 to 1999 and older written sources, Stewart and Strathern explore how the Duna have remade their rituals and associated myths in response to the outside in

March, 1944: US Army Lieutenant Billy Boyle, back in England after a dangerous mission in Italy, is due for a little R&R, and also a promotion. But the now-Captain Boyle doesn't get to kick back a

Blind psychiatrist Mark Angelotti has just enrolled in a drug trial that holds out hope of restoring his eyesight when he is enlisted to act as an expert witness in a case that is rocking the Chicago

An eye-opening account of how Congress today really works—and doesn’t—that follows the dramatic journey of the sweeping financial reform bill enacted in response to the Great Crash of 2008.The foundin

A penultimate entry in the series that includes the best-selling Hitler's War builds on the events of the previous four novels to reimagine a desperate Nazi response to a war on two fronts from the pe

Examines the poem, written in 1819, in response to a group of peaceful demonstrators being killed and injured by British troops that has inspired artists and leaders around the world and became a batt

Invite your jittery mind into quiet slips of timed or untimed writing experiments that are designed to encourage your timid heart to forge forgotten feelings and entice your shy-self to make friends w

Long before A Game of Thrones became an international phenomenon, #1 New York Times bestselling author George R. R. Martin had taken his loyal readers across the cosmos. Now back in print after almost

From one of Sweden's most successful criminal defense laywers comes an unflinching look at Stockholm's underworld. Jorge Barrio is a drug dealer who's in jail again after his accomplices flipped on hi

Even before A Game of Thrones, George R. R. Martin had already established himself as a giant in the field of fantasy literature. The first of two stunning collections, Dreamsongs: Volume I is a rare

Drug dealers, hustlers, brothels, dirty politics, corrupt cops . . . and sorcery. Welcome to Low Town. In the forgotten back alleys and flophouses that lie in the shadows of Rigus, the finest city of

IDENTIFYING THE ENIGMATIC HERO In this volume of Ghost in the Shell, Marcelo Jarty, the hero of a democratic revolution, and South American drug dealer, has been coming to Japan periodically and no

In this prequel to the highly praised The Blue Cotton Gown, Patricia Harman reaches back to her youthful experiments in living a fully sustainable and natural life in the 1960s and ’70s in rural Minne

THE BOOK BEHIND THE SECOND SEASON OF GAME OF THRONES, AN ORIGINAL SERIES NOW ON HBO. A SONG OF ICE AND FIRE: BOOK TWO In this thrilling sequel to A Game of Thrones, George R. R. Martin has created a