Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

In a letter to her daughter back East, Martha Jane is not shy about her own importance: "Martha Jane -- better known as Calamity -- is just one of the handful of aging legends who travel to London as

Together in one volume -- Hanif Kureishi's highly acclaimed and controversial novel, Intimacy, and, available for the first time, his latest collection of provocative short stories, Midnight All Day.

Breast cancer made Jennie Nash a wise old woman at the age of thirty-six. She learned, among other things, that her instincts are good, her kids are really resilient, and that, in the fight against b

Change Me into Zeus's Daughter is a haunting and ultimately triumphant memoir about growing up poor and undaunted in the South. With an unflinching voice, Barbara Robinette Moss chronicles her family'

With elegance, sympathy, and nuance, Her Infinite Variety celebrates the women in William Shakespeare's world. These lyrical stories move from Elizabethan London, where Shakespeare is drawn to the pli

Sixty years since Irma Rombauer advised new cooks to "Stand facing the stove," America's love affair with Joy of Cooking continues unabated. And why not? Joy in hand, tens of millions of people -- fr

Empirically proving that -- no matter where you are -- kids wanna rock, this is Chuck Klosterman's hilrious memoir of growing up as a shameless metalhead in Wyndmere, North Dakotoa (population: 498).

Pickett is a rich man by many of the standards that count most. A widower and retired Toronto cop, he owns his city home free and clear, he has a good pension and enough savings in the bank, and he's

"I'm as peaceful a man as you're likely to meet in America now, but this is about a death I may have caused. Not slowly over time by abuse or meanness but on a certain day and by ignorance, by plain l

Set in the 1930s at the Cold Mountain Penitentiary's death-row facility, The Green Mile is the riveting and tragic story of John Coffey, a giant, preternaturally gentle inmate condemned to death for t

Today considered a landmark of twentieth-century intellectual history, I and Thou is also one of the most important books of Western theology. In it, Martin Buber, heavily influenced by the writings

A book that belongs in every seeker's home, Spiritual Literacy answers the universal question, "How can I live a spiritual life every day?" Frederic and Mary Ann Brussat reveal a way to read the text

Finalist for the Pulitzer PrizeFinalist for the National Book AwardFinalist for the National Book Critics Circle AwardWinner of the Howell’s Medal of the American Academy of Arts and LettersOne of The New York Times Book Review’s 10 Best Books“A great American novel, a masterpiece, a thrilling page-turner.” —San Francisco Chronicle*With a new preface by Don DeLillo on the 25th anniversary of publication*Don DeLillo's mesmerizing novel was a major bestseller when it was published in 1997 and was the most widely reviewed novel of the year. It opens with a legendary baseball game played between the Brooklyn Dodgers and the New York Giants in 1951. The home run that won the game was called the Shot Heard Round the World, and was shadowed by the terrifying news that on the same day, Russia tested its first hydrogen bomb. Underworld then tells the story of Klara Sax and Nick Shay, and of a half century of American life during the Cold War and beyond.“A dazzling, phosphorescent work of art.”

A Backward Glance is Edith Wharton's vivid account of both her public and her private life. With richness and delicacy, it describes the sophisticated New York society in which Wharton spent her yout

Today, F. Scott Fitzgerald is known for his novels, but in his lifetime, his fame stemmed from his prolific achievement as one of America's most gifted (and best-paid) writers of stories and novellas.

The author of the best-selling Goddesses in Every Woman examines the experiences of the seriously ill from both a spiritual and pragmatic viewpoint and discusses how facing mortality can be a life-tra

Twenty years of experience treating men and their families has convincedpsychotherapist Terrence Real that depression is a silent epidemic in men -- thatmen hide their condition from family, friends,

Winner of the 1921 Pulitzer Prize, The Age of Innocence is an elegant, masterful portrait of desire and betrayal in old New York. With vivid power, Wharton evokes a time of gaslit streets, formal dan

A bestseller when it was first published in 1928, Edith Wharton's The Children is a comic, bittersweet novel about the misadventures of a bachelor and a band of precocious children. The seven Wheater

Out of print for several decades, here is Edith Wharton's superb satirical novel of the Jazz Age, a critically praised best-seller when it was first published in 1927. Sex, drugs, work, money, infatu

The Flynn girls, just two of a seemingly endless number of Flynn children, are naturally curious about where their little siblings come from. Well versed in the bizarre lives and gruesome deaths of

Since its original publication, Joy of Cooking has been the most authoritative cookbook in America? the one upon which millions of cooks have confidently relied for more than sixty-five years. It's t

One might not expect a woman of Edith Wharton's literary stature to be a believer of ghost stories, much less be frightened by them, but as she admits in her postscript to this spine-tingling collect

This is the first-ever English-language edition of the book Leo Tolstoy considered to be his most important contribution to humanity, the work of his life's last years. Widely read in prerevolutionar

The late Richard J. Finneran was general editor, with George Mills Harper, of The Collected Works of W. B. Yeats for many years; series editor of The Poems in the Cornell Yeats; and editor of Yeats:

An exponent of contemporary Latino literature and the founder of the Nuyorican Poets' Cafe+a7, a poetry salon in New York City, presents a cycle of poems redolent of the sights, sounds, and culture of

In a sweeping and vivid survey, renowned historian Bernard Lewis charts the history of the Middle East over the last 2,000 years, from the birth of Christianity through the modern era, focusing on th

First published in 1913 and regarded by many critics as her most substantial novel, The Custom of the Country is Edith Wharton's powerful saga about the beautiful, ruthless Undine Spragg. A woman of

Douglas Southall Freeman’s Pulitzer Prize–winning biography of Robert E. Lee was greeted with critical acclaim when it was first published in 1935. Stephen Vincent Benet said “There is a monument—and

E. Annie Proulx's Accordion Crimes is a masterpiece of storytelling that spans a century and a continent. Proulx brings the immigrant experience in America to life through the eyes of the descendants

A side from her Pulitzer Prize-winning talent as a novel writer, Edith Wharton also distinguished herself as a short story writer, publishing more than seventy-two stories in ten volumes during her li

On Death and Dying is one of the most important books ever written on the subject and is still considered the bench-mark in the care of the dying. It became an immediate bestseller, and Life magazine

How four of Europe’s most mysterious and fascinating writers shaped the modern mind.Dostoevsky, Kierkegaard, Nietzsche, and Kafka were all outsiders in their societies, unable to fit into the accepted

As told by her granddaughter, the biography of a Korean woman born in 1912 into a socially repressive, male-dominated society, describes her struggles to overcome the pains of war, loss, and discrimin

Before he gained wide fame as a novelist, Ernest Hemingway established his literary reputation with his short stories. This collection, The Short Stories, originally published in 1938, is definitive.

In this compassionate and moving guide to communicating with the terminally ill, Dr. Elisabeth Küebler-Ross, the world's foremost expert on death and dying, shares her tools for understanding ho

The magnificent, unrivaled history of codes and ciphers -- how they're made, how they're broken, and the many and fascinating roles they've played since the dawn of civilization in war, business, dip

A phenomenal worldwide bestseller for over thirty years, Richard Adams's Watership Down is a timeless classic and one of the most beloved novels of all time. Set in England's Downs, a once idyllic ru

In this book of more than 150 recipes, award-winning chef, author and teacher Rick Bayless provides the inspiration and guidance that home cooks have needed. With a blend of passion, patience, clarit

Ivan Doig grew up in northern Montana along the Rocky Mountain Front, where Dancing at the Rascal Fair takes place. He has worked as a ranch hand, newspaperman, and magazine editor and writer. His 19