Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

In the 1960s, a new addiction-treatment industry arose in America in response to an epidemic of drug use. Over the next five decades, its leaders made a relentless push to rehabilitate the casualties

The untold story of how hereditary data in mental hospitals gave rise to the science of human heredityIn the early 1800s, a century before there was any concept of the gene, physicians in insane asylu

Based on proven, rock-solid computer incident response plans The Computer Incident Response Planning Handbook is derived from real-world incident response plans that work and have survived audits a

This volume highlights the interaction between public policy and innovation. The first chapter documents the dramatic globalization of R&D and how this development has affected the efforts of 

With Oliver Wendell Holmes, Jr. and Legal Logic, Frederic R. Kellogg examines the early diaries, reading, and writings of Justice Oliver Wendell Holmes, Jr. (1841–1935) to assess his contributio

This book is intended as a guide to the analysis and presentation of experimental results. It develops various techniques for the numerical processing of experimental data, using basic statistical met

The development of Malik’s strategic framework was a result of his early realization that both business and society are experiencing one of the greatest transformations in history—a process he calls “

The contemporary opioid crisis is widely seen as new and unprecedented. Not so. It is merely the latest in a long series of drug crises stretching back over a century. In White Market Drugs, David Her

Nobel Prize winner Elfriede Jelinek is known as a writer who works in response to contemporary crises and cultural phenomena. Perhaps none of her works display that quality as clearly as On the Royal

A book that finally demystifies Newton’s experiments in alchemyWhen Isaac Newton’s alchemical papers surfaced at a Sotheby’s auction in 1936, the quantity and seeming incoherence of the manuscripts wa

In her authoritative new book, Maite Conde introduces readers to the crucial early years of Brazilian cinema. Focusing on silent films released during the First Republic (1889-1930), Foundational

Beyond the Pink Tide considers a wave of artistic and curatorial efforts and social movements that refuse national borders to think hemispherically. In modeling a transnational American Studies, the b

The idea of corporate culture is a much-discussed concept in today’s business world, but often it only comes into focus as a response to problems in the workplace. Business Culture Design change

This stunningly illustrated book in Sterling's 'Milestones' series chronicles the history of psychology through 250 landmark events, theories, publications, experiments and discoveries.

Extending back to the first demonstrations of 2011, No Turning Back dissects the tangle of ideologies and allegiances that make up the Syrian conflict. As protests ignited in Daraa, some citizens were brimming with a sense of possibility. A privileged young man named Suleiman posted videos of the protests online, full of hope for justice and democracy. A father of two named Mohammad, secretly radicalized and newly released from prison, saw a darker opportunity in the unrest. When violence broke out in Homs, a poet named Abu Azzam became an unlikely commander in a Free Syrian Army militia. The regime's brutal response disrupted a family in Idlib province, where a nine-year-old girl opened the door to a military raid that caused her father to flee. As the bombings increased and roads grew more dangerous, these people's lives intertwined in unexpected ways.Rania Abouzeid brings readers deep inside Assad's prisons, to covert meetings where foreign states and organizations manipulated the r

This book identifies the key rhetorical moves in academic writing. It shows students how to frame their arguments as a response to what others have said and provides templates to help them start makin

A groundbreaking history that puts early and medieval West Africa in a global contextPick up almost any book on early and medieval world history and empire, and where do you find West Africa? On the p

In response to unprecedented environmental degradation, activists and popular movements have risen up to fight the crisis of climate change and the ongoing devastation of the earth. The environmental

Economic and social development is a major topic of discussion in courses across the social sciences, particularly those focused on Latin America. Many scholars and instructors have tried to pinpoint,

In the years since Hurricane Katrina, the modern-day bohemians of New Orleans have found themselves forced to the edges of poverty by the new tourist economy. Modeling his work after George Orwell’s D

Sovereign wealth funds (SWFs) can be exceptionally effective tools for national resources revenue management in the current global economy. As a response to the challenges posed by financial shocks, S

The description for this book, The Art of Philosophy: Visual Thinking in Europe from the Late Renaissance to the Early Enlightenment, will be forthcoming.

This book describes the most common types of malocclusion in children and presents illustrated step-by-step guidance on the procedures employed in their management, with the focus on early interventio

Known for its accuracy and easy-to-use format, Mosby's(R) Diagnostic & Laboratory Test Reference, 17th Edition, is your one-stop resource for all the latest testing information. Tests are organized alphabetically and include vital information such as test explanations, alternate or abbreviated test names, normal and abnormal findings, possible critical values, and guidelines to patient care before, during, and after the test. This edition also includes the latest research surrounding each test. Every test entry begins on a new page and all tests are cross-referenced throughout the book to simplify lookup. The compact size, durable cover, and practical A-to-Z thumb tabs make this market-leading reference the ideal choice for anyone wanting quick and easy access to the very latest diagnostic and lab tests used in practice today.NEW! Information on Ebola and Monkey pox (mpox) is included in virus testing content.NEW! Tests are reorganized and combined with similar tests to streamline

The volume `The Early Ottoman Peloponnese: A study in the Light of an Annotated editio princeps of the TT10-1/14662 Ottoman Taxation Cadastre (ca. 1460-1463)' is a revised version of the author's PhD

How could something as insubstantial as a ghost be made visible through the material grit of stone and paint? In this original and wide-ranging study, Patrick R. Crowley uses the figure of the ghost t

Painting with Fire shows how experiments with chemicals known to change visibly over the course of time transformed British pictorial arts of the long eighteenth century--and how they can alter our co

The Board of Rites and the Making of Qing China presents a major new approach in research on the formation of the Qing empire (1636-1912) in early modern China. Focusing on the symbolic practices that

Although Czech scenographer and painter Jaroslav Malina (1937-2016) lived in turbulent times, he won international respect for his work. Spanning Malina's entire life--from his early years in the Nazi

We are now acutely aware, as if all of the sudden, that data matters enormously to how we live. How did information come to be so integral to what we can do? How did we become people who effortlessly

In the decades following World War II, municipal leaders and ordinary citizens embraced San Francisco’s identity as the “Gateway to the Pacific,” using it to reimagine and rebuild th

Across early modern Europe, men and women from all ranks gathered medical, culinary, and food preservation recipes from family and friends, experts and practitioners, and a wide array of printed mater

A widespread conviction in the need to rescue China’s children took hold in the early twentieth century. Amid political upheaval and natural disasters, neglected or abandoned children became a humanit

In the early years of the twenty-first century, China and India have emerged as world powers. In many respects, this is a return to the historical norm for both countries. For much of the early modern

In contemporary political discourse, it is common to denounce violent acts as “terroristic.” But this reflexive denunciation is a surprisingly recent development. In A Genealogy of Terror

In a publishing career that spanned less than a decade, Jane Austen revolutionized the literary romance, using it as a stage from which to address issues of gender politics and class-consciousness rar

We have grown accustomed to the idea that scientific theories are embedded in their place and time. But in the case of the development of mathematical physics in eighteenth-century France, the relatio

Sixty percent of humanity—some 4.3 billion people—live in debilitating poverty. The standard development narrative suggests that alleviating poverty in poor countries is a matter of getting the intern

An international bestseller, To Fight Against This Age consists of two beautifully written, cogent, and urgent essays about the rise of fascism and the ways in which we can combat it.In “The Eternal R

How moving beyond GDP will improve well-being and sustainabilityNever before in human history have we produced so much data, and this empirical revolution has shaped economic research and policy profo