Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

A family argument over a Buick on the first night of Chanukah results in a food fight, and when Uncle Izzy throws a latke out the window, the FBI mistakes it for a UFO. Reprint.

Ezra Jack Keats is widely acknowledged as one of the first people to feature realistic, friendly, multi-ethnic urban settings in his picture books-forever changing the landscape of children's literatu

Trapped in a tower with no door, Rapunzel is allowed to see no one but the sorceress who has imprisoned her-until the day a young prince hears her singing to the forest birds. . . . The timeless tale of Rapunzel is vividly and magnificently brought to life through Paul O. Zelinsky's powerful sense of narrative and his stunning oil paintings."Simply put, this is a gorgeous book; it demonstrates respect for the traditions of painting and the fairy tale while at the same time adhering to a singular, wholly original, artistic vision." (The Horn Book, starred review)

假如你的鄰居是那位孤僻又神祕的詩人──艾蜜莉・狄金生，故事會怎麼展開？住在對街的小女孩，因為母親受邀彈琴，意外走進詩人的世界。她悄悄送上一份小禮物，沒想到收到回贈的，竟是詩句與創作的勇氣。本書以細膩的文字，編織出一場安靜卻深刻的相遇。畫面出自兩屆凱迪克大獎得主芭芭拉・庫尼之手，濃郁的油畫筆觸重現十九世紀美國的時光氛圍。正如《出版人週刊》評價：「這是一本如狄金生詩歌般的靜謐寶石」，細讀之下，餘韻無窮。推薦給喜愛詩意故事與經典繪本的讀者。From Michael Bedard and two-time Caldecott Medal-winning illustrator Barbara Cooney comes a story about American poet Emily Dickinson and the young girl who befriends her.What if your neighbor were the reclusive poet Emily Dickinson? And what if one day she sent a letter inviting your mother to pay her a visit? A little girl who lives across the street from the mysterious Emily gets a chance to meet the poet when her mother goes to play the piano for her. There, the girl sneaks a gift up to Emily, who listens from the landing, and in return, Emily gives the girl a precious gift of her own—the gift of poetry.“This fictionalized encounter . . . is, like a Dickinson sonnet, a quiet gem: unassuming upon first glance, it is in fact deeply lustrous, with new facets becoming ap

The sequel to the "Conversations with God" trilogy explores the various ways in which the wisdom and insights of "Conversations with God" can be applied to everyday life and explains what we have to do to develop a working friendship with God.

Jack and Annie are ready for their next fantasy adventure in the bestselling middle-grade series—the Magic Tree House! It's a time for giving thanks . . . when the Magic Tree House whisks Jack and Ann

The 12 essays collected provide an in-depth study of the emergence of the new Chinese literatures by looking at the origins, themes, major authors and their works, and how creativity is closely connec

Bigger, Better, Best! (LEVEL 2: Area) In their family's new house, Jenny and Jeff are driving their little sister, Jill, crazy. Who has the bigger window? Who has the bigger bedroom? Jenny and Jeff mu

When Ike Larue is "imprisoned" at the Igor Brotweiler Canine Academy, he tries everything to get sent home--weepy letters to his owner, even illness. In reality, Brotweiler is more like camp than pris

Harry Potter is a wizard. He is in his second year at Hogwarts School of Witchcraft and Wizardry. Little does he know that this year will be just as eventful as the last.

On October 16, 1998, the world awoke to amazing news: General Augusto Pinochet, Chile's former dictator, had been arrested by Scotland Yard in England and was awaiting extradition to Spain on charges

Esperanza Ortega possesses all the treasures a young girl could want: fancy dresses; a beautiful home filled with servants in Aguascalientes, Mexico; and the promise of one day rising to Mama's positi

Mr Gumpy has decided to go for a ride in his motor car. It's a nice day and the sun is shining, so off he goes. But he only gets as far as the lane before the children, the rabbit, the cat, the dog, t

繼全球暢銷書《戀愛守則》風靡傳統約會世界後，《網路戀愛守則》為現代女性在數位時代的愛情尋覓指引新方向。當千萬女性透過網路認識異性或以電郵往來時，新的戀愛挑戰也隨之而來。本書延續原作的經典魅力，提供一套針對網路戀愛的完整法則與策略，無論妳是20歲還是50歲、科技高手或新手，都能學會如何保持自尊、提升吸引力，並建立健康長久的關係。透過一條條實用的「Do & Don’t」，幫妳避開錯誤對象，節省時間與心力，找到真正合適的那一位。What the international phenomenon of The Rules did for conventional dating, The Rules for Online Dating does for the search for love on the Internet. You'll never hit the "reply" button the same way again.Millions of women around the world are meeting men on the Internet, or they've met in person and are corresponding by e-mail. But though e-mail and Net-based dating services have revolutionized the dating landscape, they've created their own pitfalls and challenges. Women need new strategies that will improve their chances of capturing Mr. Right. Boasting the same time-tested formula and romantic spirit that made The Rules an international bestseller and launched thousands of women down the path to committed relationships, The Rules for Online Dating shows all women -- re

STAEDTLER─Made in Germany 施德樓─對品質的堅持座落於Nuremberg 的企業總部，我們很驕傲的說，我們仍堅持在德國製造，那種對品質堅守承諾的傳統。相較於全世界各大品牌，紛紛以成本考量，寧願犧牲品質的現實考量，作為德國紐倫堡施德樓基金會的公司─"Made in Germany"是一種象徵著品質的使命與榮耀，我們有75％的產品，仍堅持著由這裡生產來發送全世界。施德樓 防乾油

STAEDTLER─Made in Germany 施德樓─對品質的堅持座落於Nuremberg 的企業總部，我們很驕傲的說，我們仍堅持在德國製造，那種對品質堅守承諾的傳統。相較於全世界各大品牌，紛紛以成本考量，寧願犧牲品質的現實考量，作為德國紐倫堡施德樓基金會的公司─"Made in Germany"是一種象徵著品質的使命與榮耀，我們有75％的產品，仍堅持著由這裡生產來發送全世界。施德樓 防乾油

Jack and Annie are ready for their next fantasy adventure in the bestselling middle-grade series—the Magic Tree House! Gentle giants or giant monsters? That's the question Jack and Annie have about go

(Reference). The Techno Primer is a complete guide to the world of loop-based music styles. This book/CD pack contains an enhanced CD with techno music tracks in a variety of styles as well as vid

凱迪克得獎插畫家Ed Young用拼貼畫賦予傳統故事「瞎子摸象」新風貌，給予不同的視覺感受。六隻瞎老鼠單憑一角之感受，而妄下結論，只有最後一隻耐著性子、細心觀察的小老鼠，找到正確的答案。本故事灌輸小朋友「大膽假設、小心求證」的觀念，並且讓孩子學會閉上眼睛，用觸覺、用心去細細感受這個世界。The Caldecott Honor book and modern classic now in board

Washington Childrenu2019s Choice Picture Book AwardAn oversized paperback edition of the classic cumulative tale, perfect for sharing at bedtime, naptime…anytime!More than a foot in length and height, this big book version of The Napping House makes story time easy. Humorous and inviting, this story encourages young kids to read along—and make predictions.In the napping house is a cozy bed piled high with a snoring granny, a dreaming child, a dozing dog, a snoozing cat, and a slumbering mouse. What could be more comfy?All is at peace until the appearance of an unexpected visitor and before you know it, no one is sleeping! This classic story by Audrey Wood and illustrated by Caldecott-honoree Don Wood is a must-have for the family library.

A French Song Companion is an indispensable guide to the modern repertoire and the most comprehensive book of French melodie in any language. Noted accompanist Graham Johnson provides repertoire guid

"A bird gets its name from the simplest things - what it does, how it looks, or the song that it sings." And so Dr Seuss' famous Cat in the Hat introduces young readers to the amazing world of birds.

Some dinosaurs were big. How big? As long as four school buses in a row, as heavy as sixteen elephants.Some dinosaurs were small. How small? Read and find out!

Even the most angelic babies sometimes hit or bite, and no one-not Mommy, or playmates, or even the family pet!-is exempt when the adorable, but frustrated, toddlers in No Biting! decide to act out. B

Georgia Nicolson has started dating the Sex God (aka Robbie). So life should be perfect . . . except in Georgia's life, nothing is ever perfect. Her cat, Angus (the size of a small Labrador), is terro

When Mr. Rogers goes for a drive with Amelia Bedelia, he's in for the ride of his life. She does exactly what he tells her –– and that gets them into trouble, but only Amelia Bedel

This book is an accessible introduction to lexicography – the study of dictionaries.Dictionaries are used at home and at school, cited in law courts, sermons and parliament, and referred to by crosswo

This three-volume set is unquestionably the best reference on German SS military uniforms ever produced. This spectacular work is a heavily documented record of all major clothing articles of the Waffen-SS. Hundreds of unpublished bw photos were used in production.Original and extremely rare SS uniforms of various types are carefully photographed and presented here.

Both teachers and parents appreciate how effectively this series helps students master skills in reading, mathematics, penmanship, writing, and grammar. Each book provides activities that are great fo

Both teachers and parents appreciate how effectively this series helps students master skills in reading, mathematics, penmanship, writing, and grammar. Each book provides activities that are great fo

Both teachers and parents appreciate how effectively this series helps students master reading skills. Each book provides activities that are great for independent work in class, homework assignments,

Both teachers and parents appreciate how effectively this series helps students master reading skills. Each book provides activities that are great for independent work in class, homework assignments,

Introductory Notes 1. The Monthly Statistics is designed to give a comprehensive feature of the present social and economic conditions in Taiwan Area, Republic of China, and to provide the latest fig

‘If you are after a no-nonsense book to help you get started trading the markets, then this is the book for you.’LOUISE BEDFORD author of Trading Secrets This is a handbook in the true sense of the w

Both teachers and parents appreciate how effectively this series helps students master skills in mathematics, penmanship, reading, writing, and grammar. Each book provides activities that are great fo

Both teachers and parents appreciate how effectively this series helps students master skills in reading, mathematics, penmanship, writing, and grammar. Each book provides activities that are great fo

How did the universe begin? How hot is the sun? How long does it take to get to the moon? Find out the answers to these questions and more in Magic Tree House Research Guide: Space, Jack and Annie's v

The Tools of Government is the first professional guide to the principles and practices of public administration in an age when governments no longer provide many services--but arrange for others to d

You want girl power? Meet Annie Oakley! Born in 1860, she became one of the best-loved and most famous women of her generation. She amazed audiences all over the world with her sharpshooting, horse-ri

Introduction and Notes by Janet Beer, Manchester Metropolitan University. The House of Mirth tells the story of Lily Bart, aged 29, beautiful, impoverished and in need of a rich husband to safeguard h