Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

自由派來到川粉票倉，理解異溫層為何深信他們的美國夢被插隊？ 跨越政治分歧的暖心鉅作 同理卻不流於濫情，厚實敘事搭以深刻分析 ★本書榮登紐約時報暢銷書榜 2016年，川普以政治素人之姿當選美國總統，媒體界譽之為黑天鵝效應，而自由派則視之為平權運動的反挫。社會學家霍希爾德（Arlie R. Hochschild）造訪路易斯安那州，該地是茶黨（Tea Part

Coding for kids without a computer--an offline skill-building book for ages 5 to 7 Coding helps kids develop analytical thinking, problem-solving abilities, and beyond In this exciting guide to coding for kids, your child will discover the core concepts of coding through colorful games and activities--without using a computer. These fun challenges can be done right inside the book or with everyday objects to help kids practice the same skills coders use, like writing clear instructions, recognizing patterns, and working efficiently. There's even a place for your beginner to invent their own codes This coding for kids book features: Coding fundamentals--Practice algorithms, loops, conditionals, optimization, debugging, and variables with games that help kids think like a computer programmer. Meet the coder crew--Explore coding for kids with a whole cast of characters, including Al the helper, Pixel the creative expert, Lo the problem-solver, Bug the pattern-spotter, and their robot dog

Crack the case with Sherlock Holmes in three familiar tales, now written with young readers in mind: “The Red-Headed League,” “The Speckled Band,” and “The Hound of the Baskervilles.”It’s always an adventure with the world’s smartest detective and his trusty partner, Dr. John Watson! With mysteries galore, the daring duo can solve anything when they put their minds to it.Follow Sherlock and Watson as they track down clues and uncover the answers to strange events: a tricky business scheme; a crime in a locked room; and the appearance of an eerie, supernatural legend. Wherever the two go, the truth is sure to follow.With foil on the cover and evocative full-color art from Carlo Molinari, this adaptation of Sir Arthur Conan Doyle’s iconicSherlock Holmespromises to be an exciting first chapter book.From Starry Forest Books,Classic Adventuresbrings action-packed adaptations of favorite classics to early readers.

臺灣刑事程序法則及證據法則，邁向世界刑事訴訟思潮的主流趨勢，人權保障及程序正當衡平，經歷2003年9月大幅度修法施行，為世人所關注。立法者是作者，執法者是讀者，法律的生命在於實踐。觀察最高法院近年來新興的刑事裁判，是察覺臺灣刑事訴訟成長軌跡的最佳渠道。本書將2018年最高法院裁判大數據（Big Data），透過檢選、篩選、擷取、歸納、整理，梳理出各刑事庭、各法官所著裁判要旨，完備成書。善學者，假人

City Hall is the first book to feature striking contemporary images of the most architecturally significant city halls in the United States. This diverse collection includes New York, the oldest; Philadelphia, once the tallest building in the world; and Boston, the first major brutalist building in the United States. Organized chronologically, the book traces the evolution of American civic architecture from the early 19th century to the present day and represents diverse styles such as Federalist, art deco, and modern.Architects, current and former mayors, historians, and preservationists tell the story of how each city hall came to be, what it says about its city, and why it's important architecturally. With a foreword by noted historian Douglas Brinkley and an essay by architectural writer Thomas Mellins, City Hall spotlights these often underappreciated civic buildings and affirms architecture's unique power to express democratic ideals and inspire civic engagement.

動輒十萬字、甚至數十萬字的小說，其中人物錯綜複雜的關係、心境轉折與環境的變遷；廣大的網路訊息與文件，其中有多少潛藏的訊息等待我們發掘。文本探勘，就是要在大量文字中萃取出我們所需要的資訊。本書之撰寫，是針對完全不具備R語言能力之初學者為主要對象，以手把手的方式進行教學，讀者只要跟隨書本的章節和範例，一步一步地練習，相信必能在最短的時間內學會文本探勘的基本技術，並應用在自身所屬的領域上。包括語料庫的建

From New York Times bestselling author Mac Barnett and Geisel Award-winning illustrator Greg Pizzoli, an uproarious early reader series about a mischievous rabbit, a cranky old lady, and a lovable dog

Magical friends Unicorn and Yeti love to help each other!Pick a Book. Grow a Reader!This series is part of Scholastic's early reader line, Acorn, aimed at children who are learning to read. With easy-

From Dav Pilkey, creator of the New York Times bestselling Dog Man and Captain Underpants series, comes Dragon, the heartwarming hero adored by Dav's youngest readers!Pick a book. Grow a Reader!This series is part of Scholastic's early reader line, Acorn, aimed at children who are learning to read. With easy-to-read text, a short-story format, plenty of humor, and full-color artwork on every page, these books will boost reading confidence and fluency. Acorn books plant a love of reading and help readers grow!

當過去與現在交錯，Skeleton Keys 的鑰匙與身份也被顛覆。Wordy Gerdy 的幽靈筆將他的鑰匙從世界中刪除，為挽回一切，他與 Daisy 回到過去，卻發現關鍵道具落入神祕怪盜 Gap-tooth Jack 手中。故事圍繞想像力的威力與個人記憶的迷霧展開，節奏巧妙而充滿轉折。The third tall-but-true tale in the darkly comic new series SKELETON KEYS from the award-winning duo behind STITCH HEAD. Greetings! My name is Skeleton Keys and these fantabulant fingers of mine can open doors to hidden worlds... Join me for the curious tale of Gap-tooth Jack - thief, adventurer and champion of imagining! When Skeleton Keys banishes Wordy Gerdy from the present using his Key to Time, he thinks he's seen the last of the troublesome unimaginary.But Gerdy uses her ghostly pen to wreak her revenge, and before Skeleton Keys knows it she's written his precious keys out of existence. Skeleton Keys and his partner Daisy must follow Gerdy into the past to retrieve her pen and make her restore his keys. But Skeleton Keys has unknowingly sent Gerdy back to his own past and her pen is now in the hands of notorious thief Gap-tooth Jack.As

葛瑞絲出生於守護傳送地圖的獅鷲家族，夢想和哥哥一樣打擊罪惡。某日她誤觸任務訊號，獨自被傳送到一座神祕村莊！村裡似乎有怪物出沒，而真相比她想的還複雜。蒸氣龐克奇幻冒險，友情與勇氣交織，一場改變命運的成長旅程即將展開！"Warden Griffin at your service. Can I ask if you've seen a monster in the area ...?"Grace's family are wardens of the Griffin Map, using its teleport technology to fight crime across Moreland. Although Grace is still too young, she longs to go on missions herself. After all, if her brother, Bren, can do it, why can't she?So when Grace finds herself alone with the map when a distress call comes in, she jumps at the chance to prove she's up to the task. But the map transports Grace to a remote village where nothing is quite as it seems ... Has she taken on more than she can handle?Be transported to a world like no other in this steampunk, fantasy adventure with family at its heart from Blue Peter Book Award-winner Vashti Hardy.

A charming series filled with clever paper engineering techniques. These bright pictures move and change with the turn of every page, engaging young readers and bringing early learning concepts to lif

A charming series filled with clever paper engineering techniques. These bright pictures move and change with the turn of every page, engaging young readers and bringing early learning concepts to lif

A charming series filled with clever paper engineering techniques. These bright pictures move and change with the turn of every page, engaging young readers and bringing early learning concepts to lif

兒童聽力障礙臨床治療教育資源的權威「兒童聽力學：診斷、技術和處遇」第三版已全面更新，涵蓋此領域最新進展的前瞻主題。新的章節包括兒童的聽力和前庭問題，測試新生兒的最新方法以及人工電子耳技術的長期性研究。著名的專家Jane R. Madell、Carol Flexer和後起之秀Jace Wolfe和Erin C. Schafer對兒童聽力學的各個面向提供了細部的討論-從基礎病理學和測試到醫學、治療和手

Bumble and Bee are THANKFUL for their pal, Froggy. Froggy is thankful for a long winter's sleep.Pick a book. Grow a Reader!This series is part of Scholastic's early reader line, Acorn, aimed at children who are learning to read. With easy-to-read text, a short-story format, plenty of humor, and full-color artwork on every page, these books will boost reading confidence and fluency. Acorn books plant a love of reading and help readers grow!Autumn leaves are falling, and that means it's time for Bumble and Bee to paint pumpkins and help Froggy make a special apple pie. But when the air turns frosty, Froggy decides it's time to find a quiet place to settle in for the winter. Can Bumble and Bee and their zany antics tempt Froggy into one more cozy adventure?

Bumble and Bee are THANKFUL for their pal, Froggy. Froggy is thankful for a long winter's sleep.Pick a book. Grow a Reader!This series is part of Scholastic's early reader line, Acorn, aimed at children who are learning to read. With easy-to-read text, a short-story format, plenty of humor, and full-color artwork on every page, these books will boost reading confidence and fluency. Acorn books plant a love of reading and help readers grow!Autumn leaves are falling, and that means it's time for Bumble and Bee to paint pumpkins and help Froggy make a special apple pie. But when the air turns frosty, Froggy decides it's time to find a quiet place to settle in for the winter. Can Bumble and Bee and their zany antics tempt Froggy into one more cozy adventure?

Bumble and Bee are THANKFUL for their pal, Froggy. Froggy is thankful for a long winter's sleep.Pick a book. Grow a Reader!This series is part of Scholastic's early reader line, Acorn, aimed at childr

In The Last Last-Day-of-Summer by Edgar Award nominee Lamar Giles—now in paperback—two adventurous cousins accidentally freeze time on the last day of summer, and the secrets hidden between the seconds, minutes, and hours aren't quite the endless fun they expected!Otto and Sheed are the local sleuths in their zany Virginia town, masters of unraveling mischief using their unmatched powers of deduction. And as the summer winds down and the first day of school looms, the boys are craving just a little bit more time for fun, even as they bicker over what kind of fun they want to have.That is, until a mysterious man appears with a camera that literally freezes time. Now, with the help of some very strange people and even stranger creatures, Otto and Sheed will have to put aside their differences to save their town—and each other—before time stops for good.

This Level 1 early reader with stickers introduces young fans and reluctant readers to Luke Skywalker, one of the most iconic characters from the Star Wars Saga and features a fun new illustration sty

《金錢心理學》並非教你如何用數學公式致富，而是帶你深入理解「為何人們會這樣用錢」。作者摩根・豪澤以19篇精煉短文，揭示我們對金錢的直覺、恐懼、慾望與決策背後的心理機制。真正的財務智慧，不在於知識有多深，而是能否控制情緒與行為。在這本廣受好評的暢銷書中，你會發現投資與理財不是數學題，而是人性課。這本書適合所有想更好理解金錢與自己關係的讀者，幫你在混亂與不確定中，做出更聰明、更穩健的財務選擇。Doing well with money isn’t necessarily about what you know. It’s about how you behave. And behavior is hard to teach, even to really smart people.Money—investing, personal finance, and business decisions—is typically taught as a math-based field, where data and formulas tell us exactly what to do. But in the real world people don’t make financial decisions on a spreadsheet. They make them at the dinner table, or in a meeting room, where personal history, your own unique view of the world, ego, pride, marketing, and odd incentives are scrambled together.In The Psychology of Money, award-winning author Morgan Housel shares 19 short stories exploring the strange ways people think about money and teaches you how to make better sense of one of life’s most important topics.

The B on Your Thumb is a book of rhymes and delightful ditties to boost early reading. Each rhyme teaches a particular sound, spelling, or rule, and will delight young children with the silliness of t

Uni the Unicorn for early readers! This Step 2 Step into Reading book features Uni’s best girl friend and a cake baking contest!Uni slides down the rainbow to see the little girl—the best friend a uni

Ready, set, go! Layla and the Bots are heading to the races!Pick a book. Grow a Reader!This series is part of Scholastic's early chapter book line Branches, aimed at newly independent readers. With ea

It''s Eva Wingdale''s time to shine!Pick a book. Grow a Reader!This series is part of Scholastic''s early chapter book line Branches, aimed at newly independent readers. With easy-to-read text, high-i

Debates about the origins and effects of European rule in the non-European world have animated the field of economic history since the 1850s. This pioneering text provides a concise and accessible resource that introduces key readings, builds connections between ideas and helps students to develop informed views of colonialism as a force in shaping the modern world. With special reference to European colonialism of the nineteenth and twentieth centuries in both Asia and Africa, this book:• critically reviews the literature on colonialism and economic growth;• covers a range of different methods of analysis;• offers a comparative approach, as opposed to a collection of regional histories, deftly weaving together different themes.With debates around globalization, migration, global finance and environmental change intensifying, this authoritative account of the relationship between colonialism and economic development makes an invaluable contribution to several distinct literatures in ec

Dive into these spooky stories from New York Times bestselling author Max Brallier, perfect for beginning readers!Pick a book. Grow a Reader!This series is part of Scholastic's early reader line, Acor

The al-Sabah Collection, Kuwait, holds a spectacular array of ancient textiles that were made in Islamic lands and traded along the Silk Road, the network of ancient trade routes that linked China, Ce

本書介紹 Marie Tharp──第一位描繪出地球海底中央海嶺全貌的女性科學家。自小喜歡觀察世界、熱愛解謎的她，不願受限於時代對女性的期待。二十世紀中期，女性在科學領域並不受歡迎，海上研究更被視為「不適合女性」。Marie 因此無法登船，只能留在實驗室處理同事帶回的資料。然而，她並未因此退縮，而是逐點分析、逐張描繪，慢慢看見海底深處一條巨大裂谷的形狀。儘管科學界一開始對她的發現存疑，但她的資料與推論無懈可擊，最終證實自己觀察正確。這條海底山脈——世界上最大的地理構造——就從她狹小的辦公桌上被完整繪出。溫和呈現女性科學家的堅持與勇氣以易懂方式介紹海底地形與研究歷程適合作為科學啟蒙與女性人物傳記Meet Marie Tharp (1920-2006), the first person to map the Earth’s underwater mountain ridge, in this inspiring picture book biography from the author of Shark Lady.From a young age, Marie Tharp loved watching the world. She loved solving problems. And she loved pushing the limits of what girls and women were expected to do and be. In the mid-twentieth century, women were not welcome in the sciences, but Marie was tenacious. She got a job in a laboratory at Cambridge University, New York. But then she faced another barrior: women were not allowed on the research ships (they were considered bad luck on boats). So instead, Marie stayed back and dove deep into the data her colleagues recorded. S

1.介紹Python基礎技術與通過ICTP計算機程式能力國際認證的實用教材。 2.本書介紹的內容包含ICTP計算機程式能力國際認證-核心能力(Information and Communication Technology Programs-using Programming(Python) -Essentials Level)考試重點的

Drake needs to stop a dangerous wizard battle in this action-packed, bestselling series!Pick a book. Grow a Reader!This series is part of Scholastic's early chapter book line, Branches, aimed at newly independent readers. With easy-to-read text, high-interest content, fast-paced plots, and illustrations on every page, these books will boost reading confidence and stamina. Branches books help readers grow!Magic from a wizards' battle is destroying the city of Remus! To stop this dangerous duel, Drake and Petra team up with a Dragon Master named Tessa. Tessa, who is blind, has a very special connection with her Sound Dragon, Sono. Together, the Dragon Masters will need to find a Power Crystal! Can they save the city?

Drake needs to stop a dangerous wizard battle in this action-packed, bestselling series!Pick a book. Grow a Reader!This series is part of Scholastic's early chapter book line, Branches, aimed at newly independent readers. With easy-to-read text, high-interest content, fast-paced plots, and illustrations on every page, these books will boost reading confidence and stamina. Branches books help readers grow!Magic from a wizards' battle is destroying the city of Remus! To stop this dangerous duel, Drake and Petra team up with a Dragon Master named Tessa. Tessa, who is blind, has a very special connection with her Sound Dragon, Sono. Together, the Dragon Masters will need to find a Power Crystal! Can they save the city?

身為設計師，要怎麼做才能與工程師配合，打造出精緻的網站？身為設計師，如何善用你絕佳的美感，配置出和諧易讀的版面？身為設計師，該怎麼活用 CSS 樣式，才能點綴 HTML 內文的呈現效果？身為設計師，各行動裝置排版樣式該怎麼套用 RWD 響應式網頁的樣式？這是一本顛覆傳統寫法、創新編排的網頁設計書。本書獻給沒有程式基礎的設計師、及所有想學習網頁的初學者從文件結構、文字格式與設計，到定位方式、轉場、R

Scholastic Early Learners: Learn your ABCs with this interactive book, which guides readers through the alphabet with interactive sliders. Includes a QR link to the alphabet song!Learn to sing your AB

Discover Frog and Dog, a laugh-out-loud series for beginning readers!Pick a book. Grow a Reader!This series is part of Scholastic's early reader line, Acorn, aimed at children who are learning to read

Meet rock star Layla and her team of Bots!Pick a book. Grow a Reader!This series is part of Scholastic's early chapter book line Branches, aimed at newly independent readers. With easy-to-read text, h

From New York Times bestselling author Mac Barnett and Geisel Award-winning illustrator Greg Pizzoli, an uproarious early reader series about a mischievous rabbit, a cranky old lady, and a lovable dog

From New York Times bestselling author Mac Barnett and Geisel Award-winning illustrator Greg Pizzoli, an uproarious early reader series about a mischievous rabbit, a cranky old lady, and a lovable dog

Over almost a century, the NFL has provided fans with hundreds of unique personalities, countless unforgettable moments and some of the greatest feats of sporting brilliance ever seen. From its humble beginnings in the Midwest to the global phenomenon it has become today, the league has evolved and changed almost beyond recognition. But the exploits of the footballing heroes of years past continue to stand the test of time. Here we've collected stories on dozens of the league's most celebrated players. With Future Publishing's extraordinary content, expert commentary and lavish photography, you'll explore and rediscover the attributes that made these players, coaches and teams iconic, as well as the moments that propelled them to greatness. From early innovators like Don Hutson and Jim Brown, to modern giants such as Tom Brady, there's something for every NFL fan here.

榮獲 2020 年英國 Sainsbury’s 兒童圖書獎，《Don't Tickle the Dinosaur!》是《Don't Tickle》系列中最受喜愛的互動音效書之一。別搔癢恐龍，牠可能會咕嚕大叫喔！只要輕觸書頁就能聽見多種恐龍的叫聲，書末更有一段熱鬧的大合奏音樂，鼓勵寶寶跟著節奏舞動身體。厚頁設計安全耐用，押韻文字朗朗上口，是刺激寶寶感官、培養節奏感與語言力的絕佳工具書。Sainsbury's Children's Book Awards 2020You'd better not tickle the dinosaur... because you might just make it grunt if you do!Babies and toddlers just won't be able to resist tickling the touchy-feely patches to hear each dinosaur make a sound in this hilarious novelty book. At the end, readers will find all the dinosaurs being noisy at once in a musical finale guaranteed to get little ones dancing along. An exciting new series for babies and toddlers, from the creators of That's not my...With over 20 books to discover in this award-winning series, there is a book to excite every baby and toddler; including dinosaurs, bears, tigers, unicorns and lots more - giggles are guaranteed!Every DON'T TICKLE book supports sensory development with:- Engaging characters to encourage playfulness- Furry patche