Design Structure Matrix Methods and Applications

This volume provides a comprehensive collection of protocols that can be used to study plant chromatin structure and composition. Chapters divided into three sections detail the profiling of chromatin

This volume explores the various methods used to study tertiary lymphoid structures (TLS) in pathological situations. Pre-clinical models are also discussed in detail to show how TLS structure, develo

Following the succesful publication of "Proteome and Protein Analysis" in 2000, which was based on a former MPSA (Methods in Protein Structure Analysis) conference, Methods in Proteome and Protein Ana

This volume brings together a wide range of methods to explore the structure and function of bacterial chromatin from molecular to the cellular scale. Chapters detail experimental protocols of in

This book is about cultural models. Cultural models are defined as molar organizations of knowledge. Their internal structure consists of a 'core' component and 'peripheral' nodes that are filled by d

The study of the electronic structure of materials is at a momentous stage, with the emergence of new computational methods and theoretical approaches. Many properties of materials can now be determin

The study of the electronic structure of materials is at a momentous stage, with the emergence of computational methods and theoretical approaches. Many properties of materials can now be determined d

This volume provides readers with the latest techniques and approaches used to study K+ channels. There are a wide range of topics covered in the book, such as channel structure; K+ channels and their

Engineering Multicellular Systems: Methods and Protocols, focuses on laboratory procedures used in recent efforts for constructing synthetic multicellular systems and their applications. In particular

The "new media" -- interactive videodiscs, telecommunications, computers, VCRs, teletext systems, and more -- present researchers with new challenges when it comes to studying practical applications o

This volume focuses on explorative activity-based proteomics, biomedical applications of activity-based proteomics, and chemical strategies in activity-based proteomics providing a concise overview of

Boasting numerous industrial applications, inorganic chemistry forms the basis for research into new materials and bioinorganic compounds such as calcium that act as biological catalysts. Now complete

This book aims to provide examples of applications of atomic force microscopy (AFM) using biological samples, showing different methods for AFM sample preparation, data acquisition and processing, and

This volume provides methods to study bone morphogenetic proteins (BMPs) and BMP modulators in cell culture, in both invertebrate and vertebrate animal models, and for therapeutic applications. Chapte

This volume provides readers with a comprehensive review of various gene silencing methodologies and its applications. It provides a historical overview of gene silencing mechanisms in plants, vectors

Classic biostatistics, a branch of statistical science, has as its main focus the applications of statistics in public health, the life sciences, and the pharmaceutical industry. Modern biostatistics,

Classic biostatistics, a branch of statistical science, has as its main focus the applications of statistics in public health, the life sciences, and the pharmaceutical industry. Modern biostatistics,

The approach of SMEP-III is conceptual rather than mathematical. The authors stress the understanding, applications, and interpretation of concepts rather than derivation and proof or hand-computation

This detailed volume explores the notable progress in the field of zinc finger proteins (ZFP) study through widely used methods and protocols involving their biological functions and applications. Beg

A practical "how to" guide for multiple methods in metabolism, with a critical and objective discussion of strengths, limitations, and appropriate applications of the described methods.Edited by the w

Environmental Economics explores the ways in which economic theory and its applications, as practised and taught today, can be modified to explicitly accommodate the goal of sustainability and the vit

Environmental Economics explores the ways in which economic theory and its applications, as practised and taught today, can be modified to explicitly accommodate the goal of sustainability and the vit

This volume explores the applications of reporter gene technology and the methodologies needed for their effective implementation. The chapters in this book cover practical topics such as how to integ

Graph Searching Games and Probabilistic Methods is the first book that focuses on the intersection of graph searching games and probabilistic methods. The book explores various applications of these p

This detailed book provides state-of-the-art protocols to facilitate the construction of synthetic protein switches for a variety of applications in biotechnology and basic research. Beginning with ge

This detailed book explores the numerous applications of the yeast two-hybrid (Y2H) system, one of the most commonly used methods to detect protein-protein interactions. Beginning with an overview, th

This volume addresses the various techniques and novel applications of mass spectrometry imaging (MSI) and its role as a discovery tool in the field of proteomics, lipidomics, and metabolomics. The ch

This ninth volume in the series concentrates on in situ spectroscopic methods and combines a balanced mixture of theory and applications, making it highly readable for chemists and physicists, as well

This volume details up-to-date information and attempts to take the reader into the exciting realm of TGF-s from the basic principles to the practical applications. Chapters provide basic introduction

In spite of the widespread use of the concept of potential output in economic theory and empirical applications as well as in economic policy debates, the historical background and the assumptions inh

Richly illustrated throughout with actual tissue images, this innovative book shows that the soft-hard tissue junction is best understood in a biomechanical context. The authors describe their pioneering experimental methods, providing an essential structure-function framework for computational modelling, and thereby encouraging the development of more realistic, predictive models of this important tissue junction. Covering the three main musculoskeletal junctions of cartilage-bone, disc-vertebra, and ligament/tendon-bone, the relevant soft tissues are examined with respect to both their own inherent structure and their mode of integration with the hard tissue. The soft-hard tissue interface is explored with a focus on structural damage resulting from overloading, and its associated pathologies. Adopting a multiscale approach, ranging in structural resolution from the macro to fibril levels, this is a must-have guide to the field and an ideal resource for researchers seeking new and cr

Using multiple data sources and methods, this book involves a micro-historical analysis of the nature of change and stability in homicide situations over time. It focuses on the homicide situation as the unit of analysis, and explores similarities and differences in the context of homicide for different social groups. For example, using Qualitative Comparative Analysis, we investigate whether various social groups (e.g., men vs women, teenagers vs adults, strangers vs intimates, Blacks vs Whites) kill under qualitatively different circumstances and, if so, what are the characteristics of these unique profiles. The analysis of over 400,000 US homicides is supplemented with qualitative analysis of narrative accounts of homicide events to more fully investigate the structure and process underlying these lethal situations. Our findings of unique and common homicide situations across different time periods and social groups are then discussed in terms of their implications for criminologica

The book describes various unit operations in batch and bioprocessing and design methods for these units. Numerical methods are necessary to solve these design problems. The time-dependent nature of b

This is the first book to describe the scientific basis for the action of plant polyphenols in a wide range of technologically important phenomena. The book opens with a general summary of polyphenolic structure and a discussion of the physical and chemical basis of non-covalent molecular interactions (the process of molecular recognition) and the means by which polyphenols initiate the many and varied properties they display. There has been a big increase in interest in our ability to understand the importance of polyphenols in areas as diverse as agriculture, ecology and food selection, foodstuffs and nutrition, beverages (astringency and bitterness), natural medicines (the so-called 'French paradox'), floral pigmentation, natural glues and varnishes and the age-old methods for the manufacture of leather. The role of polyphenols in all of these areas is discussed. This book will be of value to a wide range of researchers with an interest in polyphenolics.

"This classic text presents the most recent advances in social research design and methodology. Users applaud the book's comprehensiveness. It reviews experimental, correlational, quasi experimental,

"This classic text presents the most recent advances in social research design and methodology. Users applaud the book's comprehensiveness. It reviews experimental, correlational, quasi experimental,

A strictly scientific approach to research design in architecture is no longer adequate. With contemporary considerations like behavior, health, and environmental protection, architects and students a

A strictly scientific approach to research design in architecture is no longer adequate. With contemporary considerations like behavior, health, and environmental protection, architects and students a

This book assembles experimental and bioinformatics protocols for the design and experimental testing of synthetic promoters. The identification of cis-regulatory elements potentially achieving the de

A guide to the process of conducting psychological research from the ground up — covering multiple methodologies, experimental and survey design, data analysis, ethics, and report writing.