Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

When Winnie and Wilbur discover life in miniature, the bugs in their garden suddenly seem very big indeed. It's the start of an exciting safari. But when excitement turns to survival, mini Winnie and tiny Wilbur would rather be their rightful size again.There's one small problem: teeny Winnie can't wave her whopping wand . . .Bugs, minibeasts, and creepy-crawlies are endlessly fascinating to children and they come under the spotlight in Winnie and Wilbur's latest adventure. This edition comes with a wonderful soundtrack of the narrated story with alll kinds of music and effects.

All is chaos in Year 2! An unexpected visitor, a bewitched violin and an invasion of bunnies! What can it all mean??? Look out for other Wigglesbottom titles! The Shark in the Pool The Toilet Ghost Th

In this blockbuster instalment of the bestselling Middle School series, Rafe and all the favourite characters from James Patterson's books for kids get caught up in a hilarious adventure – together fo

Join two teenage elf brothers on an extraordinary quest in this adaptation of the movie retold as comics!Set in a suburban fantasy world, two teenage elf brothers embark on an extraordinary quest to d

'Oiled with a brooding tension that never dissipates or resolves, Winter in Sokcho is a noirish cold sweat of a book.' -- Guardian'Narrated in an elegant, enigmatic voice that skilfully summons the te

Duckling is splashing in a pond, Chick is learning to sing and Little Lamb is hopping happily. Spring is here, little ones! Turn the pages and watch the faces change in this playful board book about parent and child relationships and new life in spring. Simply by turning the page, the Venetian movement causes the animal's expressions to change in front of your eyes! Reading the humorous story and watching the animated illustrations with your child will help them learn about different facial expressions and the emotions they convey. Supports your child's emotional intelligence Builds cognitive skills Expands a child's knowledge of the world around them.

This scribble-in activity book is packed full of inventions to design or discover, from real historical breakthroughs to crazy contraptions to get you out of bed in the morning. The process of inventi

Zoooooooom! We're off on an exciting space adventure in our rocket to meet all the planets of the solar system.Join in with the rhymes and spot all the smiley-faced, friendly planets, from shimmering

This paperback junior novelization retells and expands upon the exciting story of Disney/Pixar Onward—in theaters March 6, 2020!Set in a suburban fantasy world, Disney/Pixar’s Onward introduces two te

Little David grew up in Leicester on the campus of a university, where his father was a professor. As a child, he spent hours in the science library, collating his own specimens and creating a mini an

Why is there so much plastic in the world? How does it help us? What's the problem and how can we solve it? These are just some of the 60+ questions answered in this timely and topical book. The

Each of the twelve stories in this collection is the perfect length for reading aloud in about five minutes, making them perfect for jam-packed days. This treasury stars beloved characters from the Di

Look out for the Netflix original movie starring Lana Condor and Noah Centineo in 2020!In this highly anticipated sequel to the “lovely, lighthearted” (School Library Journal) New York Times bestselli

大數據與人工智慧是驅動各行各業智慧應用的核心技術，然而，大數據與人工智慧不僅包含IT技術，亦融合統計學，更可說是數據科學。本書主要目的在於讓讀者能理解大數據在IT技術上的基礎概念以及預測分析、人工智慧上的基礎演算方法與實作範例。更重要的是，協助讀者從應用情境、商業分析的角度，往下思考可能的數據分析問題與發展預測分析、人工智慧問題解決方法，諸如：聚類、分類、相似、異常、關聯、關係、鏈結、認知等以及合

A dreamlike evocation of a generation that grew up in the shadow of a dictatorship in 1980s ChileSpace Invaders is the story of a group of childhood friends who, in adulthood, are preoccupied by uneas

Through the keen eyes and curious mind of a young girl, Ying-tzu, we are given a glimpse into the adult world of Peking in the 1920s. The five sequential stories in this collection can be read as

A murdered crime writer. An idyllic Yorkshire town. Can DCI Oldroyd separate fact from fiction?A famous writer is found murdered at the Victorian baths in the Yorkshire town of Harrogate. In a crime w

Join Anna, Elsa, Sven, Kristoff, Olaf, and some all new friends for adventures in Arendelle! With 12 fantastically-frozen stories that can each be read in five minutes, this padded storybook is the pe

Who's that singing on the savannah? It's the top-five ugly animals in Africa! The wildebeest, warthog, vulture, hyena and marabou stork swagger proudly across the savannah, rejoicing in their ugliness

Duck just wants to play with his best friend Bear... the final story in the hilarious Duck and Bear series from an award-winning team!Duck wants to play in the snow.But Bear thinks it's waaaaay too co

The Thea Sisters are on a magical adventure!The Thea Sisters were are needed in Starlight Kingdomthe Kingdom of Starlight. All of the stars in the sky of the kingdom's sky have been losing their shine

A celebration of love and connection for young readersSusan Verde and Peter H. Reynolds continue their collaboration with the fourth book in their bestselling wellness series. A celebration of love in

Mark Janssen is a master in creating worlds where everything is possible. Previously we joined two brothers on a dinosaur hunt in a magical forest in Dinos Don’t Exist and travelled the oceans on the

Spend the holidays with your favorite blue cat in this in paper-over-board edition of Pete the Cat Saves Christmas!Now available in paper-over-board, Pete the Cat Saves Christmas is a perfect gift for all Pete fans at this great value price.Twas the day before Christmas and Santa was ill.In the cold winter wind he had caught a bad chill.Will Christmas be cancelled? Will it come to that?“Never!” cried Santa. “Let’s call Pete the Cat!”In this rockin’ new spin on the traditional fable The Night Before Christmas, Pete the Cat proves that giving your all in the spirit of Christmas is the totally groovy thing to do.Harperchildrens · Pete the Cat Saves Christmas

There are three simple nine-piece jigsaws and a beautifully illustrated board book in this box. Little children can enjoy a selection of detailed jungle scenes in the book, and then use the jigsaws to recreate three scenes from the book.3款9大片拼圖+1本小書拼圖完成後尺寸為17*17公分

Set in rural Nebraska, Willa Cather’s My Ántonia is both the story of an enduring friendship and a brilliant portrayal of the lives of rural pioneers in the late-nineteenth century. Part of the Macmil

Meet RORY BRANAGAN – he eats bad guys for breakfast. Well, not ACTUALLY. But he IS the best detective in town. Fifth in a hilarious comedy-crime series for readers of 8+.Hello. I am Rory Branagan. I a

The Upside-Down Magic kids are back in another topsy-turvy adventure in the next installment of this New York Times bestselling series!When Marigold's magic makes her shrink, it turns into a BIG probl

Mr Gum is back in this second hilarious book and he's as nasty as ever! In fact, he's absolutely grimsters. But this book's not just about him. Meet a gingerbread man named Alan Taylor who

Best Friends is the vividly honest follow-up to the runaway bestselling graphic memoir Real Friends.Sixth grade is supposed to be perfect. Shannon's got a sure spot in the in-crowd called The Group, a

Sitting cat, spitting cat, tangled-in-your-knitting cat, paw cat, claw cat ruining your chair!New cat, shoo cat! Living in the zoo cat, swing cat, cling cat . . . HANG IN THERE!This laugh-out-loud pic

The story of Greta Thunberg, the schoolgirl who inspired a worldwide climate change movement.It’s 20 August 2018, late summer in Stockholm, and it feels incredibly hot in the city. The TV news reports

WINNER OF THE NOBEL PRIZE IN LITERATUREWINNER OF THE MAN BOOKER INTERNATIONAL PRIZENATIONAL BOOK AWARD FINALIST FOR TRANSLATED LITERATUREA visionary work of fiction by "A writer on the level of W. G. Sebald" (Annie Proulx)"A magnificent writer." — Svetlana Alexievich, Nobel Prize-winning author of Secondhand Time"A beautifully fragmented look at man's longing for permanence.... Ambitious and complex." — Washington PostFrom the incomparably original Polish writer Olga Tokarczuk, Flights interweaves reflections on travel with an in-depth exploration of the human body, broaching life, death, motion, and migration. Chopin's heart is carried back to Warsaw in secret by his adoring sister. A woman must return to her native Poland in order to poison her terminally ill high school sweetheart, and a young man slowly descends into madness when his wife and child mysteriously vanish during a vacation and just as suddenly reappear. Through these brilliantly imagined characters and stories, interwo

his gorgeous Benji Davies title is now available in board book format!At the bottom of Syd’s garden, through the gate and past the tree, is Grandad’s house. Syd can let himself in any time he likes. B

From finding awe in the world, to understanding and embracing big feelings, the awesome activities in this book have been expertly designed to help children discover the wonder of themselves. Build co

SOON TO BE A MAJOR MOTION PICTURE. A charming memoir about the impact of Bruce Springsteen's music on a Pakistani boy growing up in 1970s Britain.Sarfraz Manzoor was two years old when, in 1974, he em

Get whisked away through time in the magic tree house with Jack and Annie in the #1 bestselling series—and meet famous Founding Father and inventor Ben Franklin!Jack and Annie know all about Ben Frank

In 1969 history was made when the first humans stepped on the moon. Back on earth, one woman was running the numbers that ensured they got there and back in one piece. As a child, Katherine Johnson lo

Book Five in the Magnificent Dune Chronicles—the Bestselling Science Fiction Adventure of All TimeLeto Atreides, the God Emperor of Dune, is dead. In the fifteen hundred years since his passing, the E

New in the critically acclaimed Little People, BIG DREAMS series, discover the life of Mohandas Gandhi, the father of India. As a young teenager in India, Gandhi led a rebellious life and went agains