Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

★ 前華爾街量化分析師揭露：演算法如何操控你的未來★ 大數據黑暗面全面曝光：看不見的歧視與不公平我們以為世界正變得更公平——由機器取代人類做決策，似乎能消除偏見。但真相，可能正好相反。在這個「演算法主宰」的時代，你能否錄取學校、拿到工作、申請貸款，甚至保險費率高低，都悄悄被一套看不見的數學模型決定。這些系統看似客觀，卻無法被檢驗，也無從質疑，一旦出錯，影響卻會層層放大。數學家暨資料科學家凱西．歐尼爾，以親身經驗揭開大數據的陰暗面：這些模型不只沒有消除不平等，反而強化既有的階級與歧視，讓弱勢更難翻身。本書如同一場警醒之旅，帶你看見科技背後不為人知的權力運作。NEW YORK TIMES BESTSELLER • A former Wall Street quant sounds the alarm on Big Data and the mathematical models that threaten to rip apart our social fabric—with a new afterword“A manual for the twenty-first-century citizen . . . relevant and urgent.”—Financial TimesNATIONAL BOOK AWARD LONGLIST • NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The New York Times Book Review • The Boston Globe • Wired • Fortune • Kirkus Reviews • The Guardian • Nature • On PointWe live in the age of the algorithm. Increasingly, the decisions that affect our lives—where we go to school, whether we can get a job or a loan, how much we pay for health insurance—are being made not by humans, but by machines. In theory, this should lead t

Chosen as one of The New York Times Best Illustrated Children's Books 2016 Little Red Riding Hood meets a wolf on her way through the woods to visit her sick grandmother. The wolf is hungry, and Red R

From TV Star to the dorkiest princess around, life is anything but dull for Nikki Maxwell! This dork-tastic bind-up features TV STAR and ONCE UPON A DORK as Nikki goes from being the star of her own r

This stylish, highly illustrated, interactive book is perfect for sharing with little children, and introduces the science of the senses using a friendly lift-the-flap format. Text is kept to a minimu

本書提供學生在研究實物上珍貴的紙引，包含分析資料與操作電腦套裝軟體。內容務實且希望能聚焦在研究分析者真正的需求上，故部分章節除了彙整實用基礎統計學外，也指導如何有效呈現數據。此書著重於協助您針對資料選擇適合的統計檢定方法，還要利用統計軟體進行分析，並將研究結果做最佳的解讀詮釋；軟體包括SPSS、Minitab、Excel和R，其中R軟體僅於此最新版中介紹。我們盡量以清楚易懂的文字介紹統計，而特殊專

ABC Animal is an entertaining early learning book with creative and captivating illustrations. Whimsical phrases and bright illustrations will help your preschooler learn the alphabet, names of animal

Claudia and her sister, Janine, may as well be from two different planets. Claudia, who pays more attention to her artwork and The Baby-sitters Club than her homework, feels like she can't compete with her perfect sister. Janine studies nonstop, gets straight As, and even takes college-level courses! But when something unexpected happens to the most beloved person in their family, will the sisters be able to put aside their differences?Raina Telgemeier, using the signature style featured in her acclaimed graphic novelsSmile and Sisters, perfectly captures all the drama and charm of the original novel!

This heartwarming book encourages positive behavior by using the concept of an invisible bucket to show children how easy and rewarding it is to express kindness, appreciation, and love by "filling bu

Summer Bridge Activities: Bridging Grades 1?2 gives students a head start for their second-grade year. Review first-grade skills such as two-digit place value and using verb tenses while preparing for

Spectrum(R) Writing for grade 5 guides students through each step of the writing process as they write aragraphs, personal narratives, fiction stories, descriptive comparisons, visual aids, how-to ins

Spectrum(R) Writing for grade 7 guides students through each step of the writing process as they write paragraphs, personal narratives, fiction stories, descriptive comparisons, outlines, research rep

Spectrum(R) Writing for grade 8 guides students through each step of the writing process as they write paragraphs, personal narratives, fiction stories, descriptive comparisons, outlines, research rep

Spectrum(R) Writing for kindergarten guides students through each step of the writing process as they write sentences, personal stories, descriptions, how-to instructions, book reports, and more. Spec

Spectrum(R) Writing for grade 1 guides students through each step of the writing process as they write sentences, personal stories, descriptions, how-to instructions, reports, opinions, and more. Spec

Spectrum(R) Writing for grade 2 guides students through each step of the writing process as they write sentences, personal stories, fiction stories, descriptions, comparisons, how-to instructions, reports, opinions, and more. Spectrum(R) Writing workbooks guide students as they write for a variety of purposes, including writing to tell a story, writing to provide information, and writing to state an opinion. Lessons support current state standards. Step-by-step instructions help with planning, drafting, revising, proofreading, and sharing writing. A Writer’s Handbook reinforces grammar and language skills, and a complete Answer Key is included. Engaging, open-ended writing projects combined with standards-based learning make these workbooks an essential resource for school success. Spectrum, the best-selling workbook series, is proud to provide quality educational materials that support your students’ learning achievement and success.

Spectrum(R) Writing for grade 6 guides students through each step of the writing process as they write paragraphs, personal narratives, fiction stories, descriptive comparisons, outlines, research reports, persuasive arguments, and more. Spectrum(R) Writing workbooks guide students as they write for a variety of purposes, including writing to tell a story, writing to provide information, and writing to state an opinion. Lessons support current state standards. Step-by-step instructions help with planning, drafting, revising, proofreading, and sharing writing. A Writer’s Handbook reinforces grammar and language skills, and a complete Answer Key is included. Engaging, open-ended writing projects combined with standards-based learning make these workbooks an essential resource for school success. Spectrum, the best-selling workbook series, is proud to provide quality educational materials that support your students’ learning achievement and success.

Your baby will love the bright photographs and 5 fun, pop-out farm surprises in Pop- up Peekaboo! Tractor. Scarecrow is waiting for the big combine harvester and it's hiding somewhere on the farm, behind a a pop-up flap. Where could it be? Is it behind the plants? Open Pop-up Peekaboo! Tractor to find out.Perfect for reading aloud and encouraging early word recognition, your baby will love the new machine and animal pop-outs in this highly popular series. Pop-up Peekaboo! Tractor is also great for developing imagination, early-thinking and memory skills.商品除瑕疵品外，恕不接受退換貨因拍攝略有色差，圖片僅供參考，顏色請以實際收到商品為準

Support students' phonetic development as they practice key first grade phonics skills. Focus on phonics with fun and engaging activity pages that are research based and support current standards. Thi

Support students' phonetic development as they practice key second grade phonics skills. Focus on phonics with fun and engaging activity pages that are research based and support current standards. Th

Using modern technology and traditional search techniques to solve mysteries including the missing female pharaoh Hatshepsut, the lost city of Ubar, and the location of explorer Sir John Franklin.

Hello, elephants and lions. Hello, penguins and monkeys. Hello, ... fun! The new Seedlings books offer irresistible introductions to six exotic but familiar animals, using a friendly voice and text cr

Cuando Libertad y tirania, del conductor radial con distribucion nacional Mark R. Levin, aparecio en los primeros meses de la presidencia de Obama, los estadounidenses respondieron haciendo de su clar

The thrilling conclusion to the brilliant dystopian trilogy that began with The Declaration. For fans of The Hunger GamesThe unimaginable has happened - Longevity, the drug that is supposed to guarantee eternal youth, isn't working.A virus is sweeping the country, killing many in its wake, and Longevity is powerless to fight it. The Outside is frightened, death is suddenly a possibility and Pincent Pharma need someone to blame.The Underground are accused of deliberately contaminating a batch of the drugs and Peter and Anna are hunted down. But someone knows the truth . . . Will they speak up or watch as everything is torn to pieces?The thrilling conclusion to the brilliant dystopian trilogy that began with The Declaration. For fans of The Hunger Games.

A paranormal action-adventure about sword-wielding guardians of the afterlife.Reads R to L (Japanese Style) for audiences T.Ichigo Kurosaki never asked for the ability to see ghosts--he was born with

A paranormal action-adventure about sword-wielding guardians of the afterlifeReads R to L (Japanese Style) for audiences T.Ichigo Kurosaki never asked for the ability to see ghosts--he was born with t

A shojo series that features handsome, manly men who have cute, girly hobbies!Reads R to L (Japanese Style), for audiences T. Asuka Masamune is a guy who loves girly things--sewing, knitting, making

Reads R to L (Japanese Style), for audiences T. Meet Maria Kawai—she’s gorgeous and whip-smart, a girl who seems to have it all. But when she unleashes her sharp tongue, it’s no wonder some consider

Having Girly Hobbies Doesn't Make You Less Manly!Reads R to L (Japanese Style), for audiences T Asuka Masamune is a guy who loves girly things--sewing, knitting, making cute stuffed animals and readin

Fight Hellfire with Hellfire!Reads R to L (Japanese Style). Raised by Father Fujimoto, a famous exorcist, Rin Okumura never knew his real father. One day a fateful argument with Father Fujimoto forces

Early one morning a little spider begins to spin her web on a fencepost and she doesn''t stop until it is finished...

Based on Ubisoft(r)'s bestselling game Tom Clancy's Ghost Recon(tm): Retribution The first Ghost Recon book charged on to the New York Times bestseller list-and now Captain Scott Mitchell and his Ghost Recon team are poised to strike again...

Reads R to L (Japanese Style), for T audiences. Ryo's grandfather becomes ill, so she decides to move to Fukuoka to take care of him. With Ryo transferring schools, does this mean that Asuka will hav

Reads R to L (Japanese Style). Having Girly Hobbies Doesn't Make You Less Manly! Asuka's friend Juta needs to keep his identity as renowned shojo author Jewel Sachihana a secret, so why is he agreein

R to L (Japanese Style). A touching, character-rich vision of an intriguing new world.

It is Ireland in the early 1950s and for Eilis Lacey, as for so many young Irish girls, opportunities are scarce. So when her sister arranges for her to emigrate to New York, Eilis knows she must go,

R to L (Japanese Style). Having Girly Hobbies Doesn't Make You Less Manly! Asuka Masamune is a guy who loves girly things--sewing, knitting, making cute stuffedanimals and reading shojo comics.

Having Girly Hobbies Doesn't Make You Less Manly! R to L (Japanese Style). With Ryo's birthday around the corner, Asuka's all aflutter making preparations for the festivities. Best-laid plans tend to

He tried to slam her with love, but she dunked his heart. R to L (Japanese Style). With just a minute remaining on the game clock, Shohoku still trails Ryonan by four points. Hoping to put this matc

R to L (Japanese Style). Asuka takes Ryo to an amusement park where he plans to confess his feelings to her. Too bad all the rides Ryo wants to go on frighten Asuka! Can he overcome his fear for the

When his hopes for trying out his new roller skates are thwarted by an untimely rainstorm, Splat the Cat finds a way to have a fun-filled indoor adventure, in an early reader that includes a focus on