Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

In this delightful book, a small boy imagines a world where dinosaurs perform public services. “Bold lines accentuate imaginative, humorous ideas. A natural for student response: students formulate their own outcomes about what would happen if the dinosaurs returned. An overwhelming favorite in the early grades.”--The Reading Teacher

Early Readers are stepping stones from picture books to reading books. A blue Early Reader is perfect for sharing and reading together. A red Early Reader is the next step on your reading journey.Horr

Beep! Beep! Sheep in a jeep on a hill that’s steep. Sheep in a Jeep is well loved by the preschool and early-reader sets for its slapstick story of five sheep (in a jeep) and silly sound effects—espec

Early one morning a little spider begins to spin her web on a fencepost and she doesn''t stop until it is finished...

When his hopes for trying out his new roller skates are thwarted by an untimely rainstorm, Splat the Cat finds a way to have a fun-filled indoor adventure, in an early reader that includes a focus on

A sweet and funny picture book about friendship - perfect for Pancake Day. Pancake recipe included! It's finally the day of Rabbit's pancake picnic! She's going to make the pancakes all by herself . .. but she can't find her recipe book. Bother! Rabbit decides to try to remember the recipe and adds syrup, strawberries, apples, and lots of other ingredients to the mixture.Her friends try to help, but Rabbit is desperate to make the pancakes on her own. Even when the mixture turns lumpy, sticky and looks, well . .. strange. Is Rabbit's pancake picnic ruined? Perhaps she just needs to accept some help from her kind friends! This beautifully illustrated picture book with its cast of adorable woodland animals combines all the fun of Pancake Day with important messages about knowing when to ask for help and the fun of working together.Children will love the fun counting element, joining in with the repeated phrases, and then making their very own pancakes using the recipe at the end of the b

From patriotic songs that stir the soul to cowboy songs of early settlers, this is a terrific collection of songs about America. Children can learn as they hear “The Star Spangled Banner,” the names

This is the story of when Winnie met Wilbur. When Winnie moves in to her big house, it's much too quiet. Winnie invites her sisters to stay, then some unusual companions - and chaos ensues! Winnie wonders if she'll be alone forever - until she spots a scruffy black cat...A heart-warming and hilarious tale revealing the origins of a truly magical friendship. Korky Paul's intricate and spellbinding artwork is full of fun, mischief and mayhem! Scan the QR code in the book to hear the story with music and sound effects!The best-selling Winnie and Wilbur series has been bewitching readers both young and old since 1987 and Winnie and Wilbur have become favourite characters in homes and schools all over the world.

Winnie and Wilbur are visiting the wild animals from their library book in real life. It's exciting to journey by magic all around the world, but there is trouble for our travellers when the animals get hungry! A whistle-stop tour full of hilarious slapstick fun, with plenty of details to pore over in Korky Paul's intricate and spellbinding artwork. The best-selling Winnie and Wilbur series has been delighting readers both young and old since 1987 and Winnie and Wilbur have become favourite characters in homes and schools all over the world.

When Winnie and Wilbur discover life in miniature, the bugs in their garden suddenly seem very big indeed. It's the start of an exciting safari. But when excitement turns to survival, mini Winnie and tiny Wilbur would rather be their rightful size again.There's one small problem: teeny Winnie can't wave her whopping wand . . .Bugs, minibeasts, and creepy-crawlies are endlessly fascinating to children and they come under the spotlight in Winnie and Wilbur's latest adventure. This edition comes with a wonderful soundtrack of the narrated story with alll kinds of music and effects.

A murdered crime writer. An idyllic Yorkshire town. Can DCI Oldroyd separate fact from fiction?A famous writer is found murdered at the Victorian baths in the Yorkshire town of Harrogate. In a crime w

Get whisked away through time in the magic tree house with Jack and Annie in the #1 bestselling series—and meet famous Founding Father and inventor Ben Franklin!Jack and Annie know all about Ben Frank

Imagine Ellen's surprise when Princess Mirror-Belle climbs out of the bathroom mirror! She comes from a world where bubble fish swim in the bath, elves sleep in slippers, and brave knights fight fire-

Nikki Maxwell’s adventures continue in the twelfth installment in the blockbuster #1 New York Times bestselling Dork Diaries series!

Even though my brother and I had decided to stay away from the magic mirror, our puppy had other plans -- he bounded right in. What choice did we have but to go in after him?When we land in a winter w

A special book and CD edition of the bestselling The Smartest Giant in Town. George wished he wasn't the scruffiest giant in town. So when he sees a new shop selling giant-sized clothes, he decides

In this heartwarming Irish fairy tale, a woodcutter is given a wish as a reward for saving the life of a small faery. The woodcutter faces a dilemma: how can he use the wish in a way that will help al

The text consists of 14 units, each illustrating the language used in a particular situation. The topic-based units cover the language learners need in everyday situations, but also language for more formal situations, such as a seminar or business meeting.Each section contains a list of the most useful phrases, with information on where and when they should be used, and a short sample of a conversation, showing the learner how a typical conversation flows in English.An audio CD contains all the conversations from the book, and allows the user to practice what they have learnt. In addition, the supplement contains all the everyday expressions and language structures that learners need to speak in natural English, organized by function.Each section also contains a glossary of useful vocabulary, making Collins Easy Learning English Conversation: Book 2 an indispensible resource for students who want to build on their conversation skills so that they can speak English fluently and with co

Take your professional game to the next level—in 100 seconds or less!People with inborn talent may be good at what they do—but only the mentally tough reach the highest plateaus in their field. And he

Extensive reading is essential for improving fluency and there is a real need in the ELT classroom for contemporary, low-level reading material for younger learners. In SpongeBob's New Toy, SpongeBob

Extensive reading is essential for improving fluency and there is a real need in the ELT classroom for contemporary, low-level reading material for younger learners. In Underwater Friends, SpongeBob S

A busy family and their friends spend a day working and playing on the farm. From milking the cows in the morning to closing the gate at night, learn about a day in the life of a farming family. Enhan

Can you understand me now? Good!Talking on the phone in a second language introduces unique challenges. What is the proper way to greet a person in Japanese? Should one be formal or informal when addr

Since it first appeared in the 1930s, the concise, clear content of the best-selling A Tune a Day series has revolutionized music-making in the classroom and the home. Now, for the first time, C. Paul

First published in 1984, a picture book in which the Little Mouse will do all he can to save his strawberry from the Big, Hungry Bear, even if it means sharing it with the reader. The Little Mous

A flock of hapless sheep drive through the country in this rhyming picture book.This Read-Along Book and CD Favorite includes a paperback edition of the book and a compact disc in a newly designed re

Colorful illustrations help demonstrate the sound of each letter in the alphabet.

Twenty-four robbers display their cooking talents in this retelling of the traditional skipping rhyme. In Audrey Wood's joyful celebration of this traditional skipping rhyme, twenty-four robbers

(Essential Elements). New keys and rhythms are introduced in this book, which can be used in a sequential or flexible format. The CD includes play-along tracks for the student that feature real player

Helen Bannerman, who was born in Edinburgh in 1863, lived in India for thirty years. As a gift for her two little girls, she wrote and illustrated The Story of Little Black Sambo (1899), a story that

Water is beautiful and useful and, in its many forms, vital to life. In this lyrical companion to The Earth and I, Frank Asch encourages young readers to appreciate anew one of our most precious resources.

Caps for Sale is a timeless classic, in print for over fifty years, and beloved by generations of readers. This easy-to-read story about a peddler and a band of mischievous monkeys is filled with warmth, humor, and simplicity. Children will delight in following the peddlers efforts to outwit the monkeys in this new, enlarged, and redesigned edition, and will ask to read it again and again.

She's in trouble again!Fun-loving Amelia Bedelia is in charge of a surprise wedding shower. And when she arrives with a garden hose, the entire party is turned into an uproarious mess!Fun-loving Ameli

Jesse Bear, what will you wear?What will you wear in the morning!My shirt of redPulled over my headOver my head in the morning.And so Jesse Bear starts his day. It isn't really an unusual day for a li

A game of hide-and-seek in the forest might lead to unexpected discoveries. Could there be something hidden in the trees?When their dog goes missing, siblings Poppy and Cy decide to play hide-and-seek

When Splat's teacher announces that the whole class is going to sing for their parents on Parents' Night, Splat is worried: he's afraid to speak in public, much less sing in public!In fact, he's so ne

I can see a nose and two eyes in the bushes!" cries Hattie. But nobody is listening."I can see a nose, two eyes, two ears, two legs, and a body in the bushes!" cries Hattie.But no one is paying a bit

"The irrepressible crew from Five Little Monkeys Jumping on the Bed returns in this version of a traditional hand rhyme . . . the familiar chant tells of five foolish monkeys who are eaten when they tease a hungry crocodile . . . the intended audience (will) delight in the mischief-making--a humorous exaggeration of their own antics".--School Library Journal. Full-color illustrations.

I can see a nose and two eyes in the bushes!" cries Hattie. But nobody is listening."I can see a nose, two eyes, two ears, two legs, and a body in the bushes!" cries Hattie.But no one is paying a bit

Peer through the die-cut windows in each page of this interactive book to find out who is playing what. Anyone can be the Music Man in this joyful adaptation of the classic nursery song, and everyon