Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Focusing on Albert Sanguinetti from his early life to his retirement from the legal sector, including his tenures in Gibraltar, Kenya, and Hong Kong, this biography provides an in-depth view of the life of a prominent figure in the legal field in the late twentieth century. It is written from an objective, external viewpoint and paints a colourful and lively picture of Sanguinetti in a voice that could almost be his own. Using Sanguinetti’s life experiences, the biographer touches on various historical events, including the Mau Mau revolution in Kenya and the 1957 riots in Hong Kong, and details the social and political problems of the times, such as lingering colonialism, class structure issues, and human rights violations, among others. These glimpses of history through Sanguinetti’s eyes are accessible, thought-provoking, and truly representative of the man himself.Offering a well-rounded image of the eccentric subject, this book fulfils Sanguinetti’s common response to questions ab

The Hong Kong Cemetery in Happy Valley is home to over 470 graves connected to the city’s Japanese population. Most of these graves belong to individuals who died during the Meiji era (1868–1912), a remarkable period of modernisation and opening up of Japan that saw thousands of its inhabitants travel to other parts of the world to study, work, and settle. Who were these people? What were they doing in Hong Kong? And why were unbaptised Japanese buried in what was called at one time the ‘Protestant Cemetery’?Hong Kong’s Meiji-era Japanese community was one of two halves. Company executives sat atop the social ladder and karayuki-san, or prostitutes, occupied the lower echelons, with tradespeople and professionals somewhere in between. By revealing the personal journeys of these mostly forgotten Japanese, the authors aim to add to transnational perspectives on Hong Kong and Japan during the late nineteenth and early twentieth centuries, as well as increase recognition of this fragmented

Prof. William S-Y. Wang, an eminent linguist, has made significant contributions to the field regarding lexical diffusion, experimental phonetic studies, language simulation and modeling, and aging and language. To celebrate his 90th birthday, colleagues and friends worldwide have contributed over 30 articles to a two-volume Festschrift. The English volume includes topics such as Chinese language evolution, the relationship between language and music, and the brain processes involved in language production. This Festschrift is written by and for experienced language researchers and is also suitable for students of Chinese linguistics and those interested in Chinese culture, history, and neurology.

In Paths of Justice, Johannes Chan illuminates fundamental themes and basic values in Hong Kong’s legal system by using his own experience and drawing on interesting and important cases. The book expl

This edited volume seeks to highlight the development of play therapy in various countries and cities in Asia. The editors discuss how mostly Western play therapy approaches are adapted for use in Asi

INTRODUCTIONThe book provides guidelines and practical creative exercises which equip creative-major students in early semesters as well as creative practitioners with fundamental knowledge on creatio

Revitalization in Asia: Adaptive Reuse in Macao, Mumbai, and Penang offers a clear understanding of the value of sustainable adaptive reuse within an Asian context. Three highly urbanized places (Macao, Mumbai, and Penang) are considered in detail from conservation and planning perspectives (with essays and timelines for each). For each place, five case studies offer a comparative framework for understanding similarities and differences in adaptive reuse projects. Six essays examine adaptive reuse in terms of its connection to the three dimensions of sustainability, with reference to the United Nations’ Sustainable Development Goals. This book is envisioned as a continuation of Asian Revitalization: Adaptive Reuse in Hong Kong, Shanghai, and Singapore.

Benny Chia’s memoir of life on the fringe is a vivacious slice of Hong Kong’s life and cultural development at a time of minimal institutional support. His colourful and anecdotal story will interest culture practitioners as well as the general reader curious about the Fringe Club and its role as a seedbed for local artists and as a venue for international ones, both functions championed by Benny at the helm of this small but important institution housed in a distinctive former ice house in Central. general reader curious about the Fringe Club and its role as a seedbed for local artists and as a venue for international ones, both functions championed by Benny at the helm of this small but important institution housed in a distinctive former ice house in Central.

Following the ending of the First Opium War and the signing of the Treaty of Nanjing in 1842, Britain opened five treaty ports on the Chinese mainland in the cities now known as Fuzhou, Guangzhou, Ningbo, Shanghai, and Xiamen. Foreigners were allowed for the first time to live and work normally in these cities under the eyes of their state’s consul. In establishing this presence, consular staff and their families faced numerous challenges, including unsuitable accommodation, illness, hostile local authorities, attacks from militias and pirates, while at the same time adjusting to an unfamiliar language and culture.Henrietta Alcock (1812–1853), the first wife of the British Consul, Rutherford Alcock, was little-known until an album of sketches and watercolours depicting her life in China came to light. Acquired by the Martyn Gregory Gallery, London in the early 1990s, the works in the Alcock Album feature picturesque natural landscapes, traditional Chinese architecture, and scenes of co

Psychopathology: An Empathic Representational Approach retraces the foundations of classical phenomenological psychopathology and integrates them with modern ideas drawn from anthropology, cognitive neuroscience, computational science, and evolutionary biology to synthesize a comprehensive framework and provide fresh insights.This book explores how the scientific concepts of ‘information and representation’ can be used to understand subjective mental phenomena and integrate them in empathic clinical dialogues during interactions with patients. It explores key issues in clinical psychopathology coherently and systematically, illustrates advanced topics in an accessible manner using clinical case examples, metaphors and clarifying diagrams, and directly links advanced conceptual frameworks with pragmatic skills in the clinical dialogue process.This volume is aimed at a broad audience of mental health professionals, researchers, and students in psychiatry, psychology, and social work. Its

The introduction of elections to district advisory bodies during the early 1980s was expected to improve the public delivery of services. However, as time passed, electoral politics led to party politics, elite fragmentation and political struggles. Politicization and hyper-politicization in the Hong Kong Special Administrative Region has brought about a fluctuating pattern between administrative recentralization, the Tsang administration’s attempts at decentralization, and the post-2019 administrative recentralization.The purpose of this book is to study the intertwining relationship between district administration and electoral politics. It also examines the political transformation of District Councils after the promulgation of the National Security Law in late June 2020. Written by experts in the field, this book is a good reference source for readers interested in district elections, politics, and administration in Hong Kong.

This book examines Hong Kong foodways in different periods of social development and hopes to advance anthropological inquiries by addressing issues concerning identity, migration, consumerism, globalization, and the invention of local cuisines in the context of Hong Kong as a fast-changing society in East Asia.

Using the insurrection by the Malayan Communist Party (1948–1960) as an example, this book argues that resorting to violence sped up the decolonisation of British Malaya, begging the question: if a la

Bugis Street was famous (or notorious) for being a haunt of transgender prostitution in the early decades of postcolonial Singapore. Since then the site has been a source of touristic obsession and lo

For readers interested in China depicted by western travellers in the late 19th and early 20th centuries, this set focuses on the theme "The Silk Road" and features five books written by explorers from various walks of life, including:Through Hidden Shensiby Francis H. Nichols, 1902In Forbidden China: The D'Ollone Mission 1906–1909;China—Tibet—Mongoliaby Vicomte d'Ollone, 1911Across China on Foot: Life in the Interior andthe Reform Movementby Edwin J. Dingle, 1911Among the Celestials: A Narrative of Travelsin Manchuria, Across the Gobi Desert,Through the Himalayas to Indiaby Francis Younghusband, 1898In the Footsteps of Marco Polo: Being the Accountof a Journey Overland from Simla to Pekinby Clarence Dalrymple Bruce, 1907Each volume of the collection aims to reignite interest and also to allow readers to explore how these books relate to the region today.

This book offers a glimpse into the wide-ranging 50-year career of the internationally renowned Hong Kong photographer/designer through his work in collages and photomontages. From his early album covers when he was an art director/designer for the music industry in New York, Los Angeles and London in the 1970’s, through his diverse international assignments and personal works, to his most recent exhibition in Hong Kong. The story encompasses the long journey from cut-and-paste collages to the computer-composited photomontages of dreamscapes in this Carnival of Dreams.In his introduction titled ‘The Man from Everywhere’, Pico Iyer writes: “For decades now, Basil Pao has been the global eye through which I’ve taken in almost every country, as clearly as the world within… I never know where to place Basil; I can’t get my head around him. Album-designer, loving father, covert Chan master—21st century Renaissance man—Basil is always bringing the many worlds inside him together to create so

The COVID-19 pandemic was a global crisis that affected millions of lives and brought mental health challenges to the forefront. In Hong Kong, the situation was worsened by uniquely strict COVID-19 regulations, quarantine measures, and travel restrictions. The mental health issues associated with the pandemic did not end with the lifting of the mask mandate. On the contrary, the repercussions are only just beginning to surface and their impact will be felt for years to come.This eye-opening book tells the stories of ordinary Hongkongers who faced extraordinary challenges during the pandemic. Through a blend of first-person accounts, psychological insights, and hard data, it offers a compelling and accessible exploration of the toll that the COVID-19 pandemic has taken on mental health in Hong Kong.However, this book is not only a chronicle of suffering; it is also a guide to healing and hope. It offers practical advice on how to overcome the mental health issues caused by the pandemic,

Fills a gap in Korean Wave studies by studying it through the lens of gender. Women We Love is an edited collection exploring femininities in and around the Korean Wave since 2000. While studies on the Korean Wave are abundant, there is a dearth of analysis about the female-identifying stars, characters, and fans who shape and lead this crucial cultural movement. Using "women" as an inclusive term extending to all those who self-define as women, this collection of essays examines the role of women in K-pop and K-drama industries and fandom spaces, encompassing crucial intersectional topics such as queering of gender, dissemination of media, and fan culture. The audience for Women We Love will reflect the contributors to this text; they are K-pop and K-drama fans, queer, international; they are also academics of Asian histories, sociology, gender and sexuality, art history, and visual culture. The chapters are playful, intersectional, and will be adapted well into syllabi for media stud

We have carefully selected a collection of 20 exquisite paintings and calligraphy by Prof. Jao Tsung-i, accompanied by 50 cherished photographs captured during his worldwide travels. These features Prof Jao’s interpretations of landscapes from different corners of the world, including his large-scale paintings depiction well-know sites in Hong Kong, China, and overseas. We can observe how he exceptionally reflected the distinct character of each place and represented it using the traditional Chinese medium of ink and brush as well as Western painting style. As the old saying goes, “It is better to travel ten thousand miles than to read ten thousand books”. While achieving one of these is already incredibly challenging, Prof. Jao not only traversed thousands of miles, surpassing the accomplishments of both ancient masters and numerous contemporary painters.

English novelist E.M. Forster wrote his last and best-loved work, A Passage to India, both as a paean to his love for India and as a tribute to the relationships he formed with Indians. Forster became entranced by the India of the Raj at a young age, and his love affair with the sub-continent, its princes, and peoples, was to last all his life. At his most socially transgressive, it was with Indians that Forster chose to connect and with whom he put into effect his belief in man’s duty to value friendship over state or ideology. His time in India was undoubtedly when he was at his most human and most vulnerable.At once a contemporary reflection on India’s rich history and a biographical retelling of Forster’s travels through the country in the early 1900s, Developing the Heart delves into the past to better understand the profound impact certain events and people had on his writing. In doing so, it allows readers to look on as Forster matures and softens over time in his behaviour with

First published in 1968, this volume of essays, posthumously edited by the author’s brother Professor C. T. Hsia (a prominent Columbia University professor of Chinese literature), focuses on Chinese literary criticism relating to the work of leftist Chinese writers, including Lu Hsün, Chiang Kuang-tz’u, the “Five Martyrs,” and Chü Ch’iu-po, who were sympathetic to the ideals of the pre-1949 Chinese communist party. As one of the few foundational texts to provide a critical overview of the aesthetics and politics of China’s leftist literary movement, The Gate of Darkness examines the conflicting dilemmas between leftist authors’ own ideals and the strict ideological frameworks imposed by the propaganda policies of the Chinese communist party in the early twentieth century.Hsia’s essays are exciting reading precisely because Mr. Hsia approached his subject not merely with the index-cards of a historian but also with the sensitive eyes of a novelist. Tsi-an Hsia is a creative and compassi

For students of Chinese art and culture this anthology has proven invaluable since its initial publication in 1985. It collects important Chinese writings about painting, from the earliest examples th

The third edition has undergone significant revisions from the second edition, which was published in 2011. Significant enhancements include coverage of　advancements in electronic commerce and financialtechnology (fintech), particularly the adoption of blockchain-based letters of credit and internet of things. Readers will gain valuable knowledge about trade developments in fintech, blockchain, and important trade promotion institutions in the Greater Bay Area.This book offers comprehensive and well-structured content, making it an excellent resource for training professionals such as bankers, import/export managers, and lawyers.It is particularly beneficial for students enrolled in the Finance of International Trade module of the Professional Diploma for Certified Banker offered by the Hong Kong Institute of Bankers, helping them prepare effectively for their examinations.

Revelations of China’s global influence and intentions, from one of its most respected foreign policy analysts.For Washington, China is a strategic competitor: the only country with both the will to reshape the world order and, increasingly, the means to do so. For Europe, the People’s Republic is a ‘partner for cooperation, an economic competitor and a systemic rival’. For NATO, it is a ‘decisive enabler’ of Russia’s war against Ukraine. Yet Beijing’s image is far more positive in the Global South, of which the PRC considers itself a part.Zhou Bo’s essays unpack China’s own view of its role today. The PRC is operating not only in a world becoming less Western, but—more importantly—a West becoming less Western; and the key to its outlook lies in Africa, the Middle East and the Indo-Pacific as much as in Europe and the White House.Are Moscow and Beijing really so closely aligned? Where are Sino-Indian relations headed? Is China a new Cold War foe for the West? Or will economic ties inev

My Mum Called Alzheimer’s is a heartfelt memoir chronicling the author’s journey through her mother’s battle with dementia in the final 4 years of her life. In a diary of intimate dialogues between mother and daughter, we glimpse into the challenges of caring for someone you love, coming to terms with losing them, and finding strength in cherishing the moments that remain. The touching account of the interaction between the author and her mother sends a strong message about keeping a balance, maintaining dignity whilst coping with the effects of the symptoms of dementia and the need to make the best of what we still have. It is a story of love, resilience, perseverance, and hope.

In A New Documentary History of Hong Kong, 1945–1997, Florence Mok, Fung Chi Keung Charles, and other contributors analyse newly released archival records from the National Archives in London, the Government Records Service in Hong Kong, and other sources across the world. This documentary collection provides an updated and improved understanding of basic aspects of the city such as governance, economy, society, and culture. It also aims at investigating topics that are under-exploited in previous sourcebooks, such as race and diasporas, gender and familial relations, medicine and healthcare, and environment and natural disasters. Overall, this book offers an innovative and comprehensive long-term perspective of Hong Kong’s colonial history.

In an epic historical story that talks directly to our times, Cross and Dragon dramatizes the life of one of the most famous Western figures in China: Italian Jesuit Matteo Ricci. Sent by the Pope in the late 16th century to convert the Chinese Emperor, Ricci was faced with a “mission impossible” as China in the Ming Dynasty did not allow foreigners to enter the country.

From humble beginnings in Hong Kong, Yuen Kwok-Yung rose to international prominence as an academic, physician, and microbiologist. As an advisor to governments, he and colleagues made discoveries that helped the world cope in often controversial ways with unprecedented threats to public health, including the COVID-19 pandemic. In this compelling memoir, Dr. Yuen weaves personal stories with those from his extraordinary medical careers to take readers on an inspiring journey about perseverance, courage, faith, and the ongoing peril of infectious diseases. threats to public health, including the COVID-19 pandemic. In this compelling memoir, Dr. Yuen weaves personal stories with those from his extraordinary medical careers to take readers on an inspiring journey about perseverance, courage, faith, and the ongoing peril of infectious diseases.

The inspiring, haunting story of Chinese migrant workers rejected by the USA who built a new community in Mexico.From the 1850s, as the United States pushed west, Chinese migrants met ordinary Americans for the first time. Alienation and xenophobia lost the US this chance for cultural and economic enrichment—but America gave the Chinese new perspectives, connections, and dreams of their own. As teenagers, Hugo Wong’s great-grandfathers fled poverty in Guangdong for California. A decade later, excluded from the US, they helped establish a Chinese settlement across the border in Mexico, led by a world-famous dissident-in-exile with visions of a New China overseas. They would be among the Americas’ first Chinese magnates, meeting with presidents, generals, and missionaries, living through astonishing victories and humiliating defeats. The bitterest of all would be the colony’s tragic demise amid a violent Mexican revolution, leading to the largest massacre and deportation of Chinese in Am

In ancient times, scholars such as Confucius and Aristotle expounded on the virtue of the “middle way” or “intermediate,” an ideal point of moderation or balance between the extremes of human behavior. Adam Smith, widely considered the father of modern economics as we know it, also encouraged propriety in his first work, The Theory of Moral Sentiments. Since then, different schools of economics have continued to incorporate the idea of propriety into their theories, for example in such concepts as equilibrium and bounded rationality, though few economists have defined it explicitly. In light of growing uncertainty and polarization around the world, propriety economics offers alternative solutions for markets, governments, and everyday citizens.This book embarks on a thorough review of Eastern and Western philosophies of propriety over the past 2,500 years, followed by an investigation of the ideas of propriety found in five key schools of economics: classical, neoclassical, institution

Population ageing is a challenge to societies worldwide in terms of healthcare, social support, community infrastructure, and more. With one of the longest life expectancies in the world, Hong Kong will soon see a dramatic increase in the number of older residents together with a decrease in the old age dependency ratio. This book provides a timely examination of the current status and services available for Hong Kong’s ageing population in four key areas: general healthcare needs, such as health promotion and lifestyle modifications; specific healthcare needs, including care of chronic conditions and hip fractures; psychosocial needs for older people with intellectual disabilities and impairments, as well as the needs of their caregivers; and environmental and technological needs in relation to universal design, information and communication technology, and telehealth.Drawing from a wide range of experience in local professional settings combined with international best practices, the

This book, the first of its kind in Hong Kong, offers insights from experts in healthcare and higher education both locally and further afield. Key learnings and recommendations are presented in three sections: disaster management and reconstruction, including what we can learn from past earthquakes; the importance of healthcare and emergency medicine in disasters and community events; and the way forward, in particular how technology and systems thinking can be used for disaster mitigation.

Shao Xunmei, poet, essayist, publisher, and printer, played a signifcant role in the publication and dissemination of journals and pictorial magazines in Shanghai during the 1920s and 1930s, but this is the first collection of his prose writings to be published in English. The essays in this book, some of which were selected by the writer's daughter, Shao Xiaohong, include long essays such as “One Man Talking” and “A Year in Shanghai” as well as several shorter essays on subjects as diverse as the caricatures of Miguel Covarrubias, woodblockprinting, and pictorial magazines—all of which were published in Shao’s own magazines.

An examination of the 1970s art and culture scene in Hong Kong through the lens of an independent youth magazine. Taking The 70's Biweekly--an independent youth publication in 1970s Hong Kong--as the main thread, this edited collection investigates an unexplored trajectory of Hong Kong's cultural and artistic production in the 1970s. The 70's Biweekly stands out from many other independent magazines with its unique blending of radical political theories, social activism, avant-garde art, and local literature. By taking the magazine as a node of social and cultural activism from and around which actions, debates, community, and artistic practices are formed, this book fills gaps in the study of how young Hong Kong cultural producers carved out an alternative space to speak out against established authorities. Split into three parts, The 70's Biweekly provides readers with a panoramic view of the political and cultural activism in Hong Kong during the 1970s, featuring writings on art and

The rapid developments of electronic communication in the past decades have resulted in a huge amount of clinical knowledge becoming readily available to patients and the general public. At the same time, with the increasing number of complaints and court cases relating to healthcare disputes, knowledge in healthcare ethics and law is increasingly important in the education, training and practices of lawyers as well. This book aims at helping healthcare practitioners (HCPs) to gain some basic and practical knowledge in the two important areas of clinical ethics and laws, so that they will become better practitioners upholding the standard of care, concentrate on taking care of their patients and stay away from unnecessary legal battles.

Includes practical advice, up-to-date legal insight, and easy-to-use checklists.Suitable for people working behind and inside construction sites.Real examples and application in Hong Kong.This book is aimed at students taking occupational safety and health courses at the universities, Construction Industry Council and Occupational Safety and Health Council. It will also serve as a reference book for registered safetyofficers, safety managers, insurance surveyors, project managers, site agents,safety engineers and occupational safety officers as well as those involved in promoting occupational safety in the construction industry and preventingaccidents on construction worksites.

Reverse paintings on glass occupy a special place in Chinese art, spanning the genres of glass working, export art, folk art, erotica, and meiren hua (paintings of beauties). Their unique appearance is the result of a challenging production process in which artists layer pigments in the reverse order of the normal painting procedure–highlights first, then mid-layers, and finally base colours. The final product is viewed in reverse from the opposite side of the glass, which must also be considered when creating the paintings. A product of the encounter between East and West, the manufacture of glass paintings in China was stimulated by European glass paintings brought to the imperial court by traders and diplomats in the seventeenth century. Initially made in Canton for Western consumers, by the eighteenth century their production had spread throughout China, with subjects and styles adapted to suit local tastes. The glass paintings in the Mei Lin Collection represent this later floweri

High Gothic: Christian Art & Iconography of the 13th–14th Century showcases classic examples of statuary, stained glass, diptychs, textiles and caskets that were used in the expression of Christian devotion in Western Europe.‘Gothic’ was originally a derogatory term coined by scholars during the Renaissance to describe the ‘barbaric’ medieval architecture that arose with the decline of the classical forms of the Roman Empire. The word is now understood to describe a style of buildings and objects created between the twelfth and fifteenth centuries which incorporate elements such as novel advances in masonry work and the characteristic ogival arch.The Gothic period saw an increased emphasis on the power of images, where vision became an active force for activating emotion and inspiring contemplation. The great cathedrals constructed in this period―with their thin walls and high vaults filled with statuary and stained-glass windows―were designed to evoke awe among visitors. The exqui

An individual’s health depends on their personal lifestyle and living conditions, which are influenced by a host of complex physical, social, and economic determinants. The same is true of organisatio

This is a story which begins in California and ends in China. It is a detective tale with a subtle love interest. Victor Lin, a Chinese-American died in mysterious circumstances on a trip to the Thous