Solid-Phase Extraction: Principles And Practice

Divided into three main parts, the book begins with a clear explanation of basic SPE conceptsincluding theory, chemistry, and mechanisms of interaction as well as methods development, troubleshooting, and optimization. The next section presents an in-depth look at SPE applications, with separate chapters devoted to clinical, environmental, and natural product chemistry. Numerous examples drawn from each of these three areas illustrate SPE in action in the real world, successfully bridging the gap between principles and practice.

The final section of this book discusses the latest SPE technology, with detailed coverage of the automation process, solid-phase extraction disks, and innovations such as solid-phase microextraction and small-volume solid-phase extraction. Suggested reading and references are included throughout, providing a useful springboard for further research and study.

Whether you are new to SPE or are looking to keep abreast of the newest developments in SPE methods and uses, Solid-Phase Extraction gives you instant access to the information you needan essential companion for chemists of all types who use SPE in their work.

Complete coverage of SPE concepts and applicationsat your fingertips Solid-Phase Extraction (SPE) equips chemists in any field with an incomparable one-stop source of up-to-date information on SPE. With sections devoted to fundamental principles, applications, and new technology, it is both comprehensive and easy to use the ideal working reference on this important subject.

Presents a straightforward examination of SPE theory, methods development, chemistry, and mechanisms of interaction

Provides detailed coverage of SPE applications in clinical, environmental, and natural product chemistry

Features practical examples illustrating a range of real-world SPE uses

Prepares chemists to make informed decisions on sorbent selection

Covers the latest SPE technology, with valuable insights on automation and new sample preparation methods

Offers suggestions for further reading, Internet resources, and product guides

E. M. THURMAN is an organic geochemist at the U.S. Geological Survey with twenty years of research experience in the environmental chemistry of water and soil, as well as extensive experience in sorption chromatography and XAD and SPE resin technology. Dr. Thurman has published research papers on the theory of XAD resins, applications of SPE in environmental chemistry, drug applications of SPE, and isolation of natural products by SPE and ion exchange. He is the coauthor of Immunochemical Technology for Environmental Applications, the coeditor of Herbicide Metabolites in Surface Water and Groundwater, and has written over 80 journal articles on environmental analytical chemistry.

M. S. MILLS is a research envi-ronmental chemist with Zeneca Agrochemicals at the Jealott's Hill Research Station, Bracknell, U.K. Dr. Mills was formerly employed by the U.S. Geological Survey in Lawrence, Kansas, where her research interests included exploring the mechanisms and applications of solid-phase extraction in environmental chemistry, investigating the organic geochemistry of naturally occurring aquatic foams, and the degradation and transport of xenobiotics in the vadose zone. She has contributed numerous publications and oral presentations on these topics over the past five years, and was cofounder and co-lecturer of the American Chemical Society short course, "Solid-Phase Extraction in Environmental and Clinical Chemistry." Current research project foci include the degradation and transport of xenobiotics in the vadose zone using radiolabeled techniques and the degradation of xenobiotics in the saturated zone.