Capillary Electrophoresis - Mass Spectrometry (Ce-Ms) - Principles And Applications

This monograph offers the reader a complete overview on both principles and applications of CE-MS. Starting with general considerations on detection and hyphenation in CE, also related and more specialized techniques such as chromatographic preconcentration and CIEF-MS are discussed. A special emphasis is put on CE-MS interfaces, which are described in detail. Applications to all relevant substance classes are discussed in distinct chapters, each written by experts in the respective fields. Besides classical applications in proteomics and pharmaceutical chemistry, recent implementations in food science, metabolomics, and forensic analysis are highlighted. An unique source of knowledge for everyone dealing with CE-MS.

Gerhardus (Ad) de Jong studied chemistry in Utrecht, the Netherlands, and received his Ph.D. at the Free University of Amsterdam. He worked for Duphar, a pharmaceutical company in Weesp, the Netherlands, in the department Analytical Research. Subsequently, he returned to the Free University as associate professor in the Department of Analytical Chemistry. In 1990, he again moved to the pharmaceutical industry and was appointed to section head Chromatography of Solvay Duphar. In 1995, he was appointed professor in Analytical Chemistry and Pharmaceutical Analysis at the University Centre for Pharmacy, Groningen, the Netherlands, and since 2001, he is professor in Pharmaceutical Analysis at the Department of Pharmaceutical Sciences, Utrecht University.
Prof. de Jong is (co-)author of more than 250 papers in various scientific journals and some book chapters. He is co-author of a book on chromatography and was editor of the Journal of Chromatography B from 1998 to 2003. His research interests encompass separation techniques and their applications in pharmaceutical analysis, bioanalysis and analysis of biomacromolecules.