Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

“An apple got Adam and Eve thrown out of paradise. In Linda Joan Smith’s glowing debut novel, a peach shows a thirteen-year-old girl the way in.” —The New York Times Book ReviewThe night that workhouse orphan Scilla Brown dares to climb the Earl of Havermore’s garden wall, she wants only to steal a peach—the best thing she’s ever tasted in her hard, hungry life. But when she’s caught by the earl’s head gardener and mistaken for a boy, she grabs on to something more: a temporary job scrubbing flowerpots. If she can just keep up her deception, she’ll have a soft bed and food beyond her wildest dreams . . . maybe even peaches. She soon falls in with Phin, a garden apprentice who sneaks her into the steamy, fruit-filled greenhouses, calls her “Brownie,” and makes her skin prickle. At the same time, the gruff head gardener himself is teaching lowly Scilla to make things grow, and she’s cultivating hope with every seed she plants. But as the seasons unfurl, her loyalties become divided, and

A gorgeous collector's edition of the pulse-poundingthird novel in Alex Aster's #1 bestsellingLightlark SagaThis gorgeous collector’s edition of the thrilling third novel in Alex Aster’s #1New York TimesbestsellingLightlark Sagaincludes a suite of sensational features:Premium metallic slipcaseSatin cover with foil stampingMap-illustrated endpapersStenciled edgesEight pages of full-color character art and scene illustrationsAn eight-page bonus romance scene written in the POV of Isla’s love interestLove kills kingdoms . . .Back in Grim’s castle on Nightshade, Isla is reeling in the wake of a brutal battle and the devastating truths it exposed. Her future—and the fate of the world—now hinge on a heart split in two.Past Isla, who fell in love with the ruler of Nightshade, fights to resist feelings she considers treasonous. The Isla of the present, who has seen the ruin her powers can cause, will do anything to save Lightlark and its king.As the line between enemy and friend is tested, Isl

Meet the Funjeepups, three curious and adorable woodland critters, in this "first comic" picture book series from the creator of Kitties on Dinosaurs!In this story, Button, Dot and Dollop get a music lesson from a feathery friend!Button, Dot and Dollop love exploring the magical forest they live in. They love vine swinging. They love guppie bumping. They love making nature art. But what they love most is returning home after an exciting day of adventuring.When out on a morning walk, the Funjeepups spot a friendly bird who sings them a beautiful song — which inspires the Funjeepups to create their own song. But unfortunately, they can't play any instruments! Thankfully, their feathery friend is there to lend a helping wing.Young readers will be inspired to create their own song alongside the Funjeepups in this light and funny picture book series by Michael Slack!Series Overview: Join Button, Dot and Dollop on their exciting woodland adventures in this sweet and easy-to-read "first comic

Meet the Funjeepups, three curious and adorable woodland critters, in this "first comic" picture book series from the creator of Kitties on Dinosaurs!In this story, Button, Dot and Dollop go on an overnight camping adventure!Button, Dot and Dollop love exploring the magical forest they live in. They love vine swinging. They love guppie bumping. They love making nature art. But what they love most is returning home after an exciting day of adventuring.The Funjeepups want to make a wish on a star, so they decide to go on an overnight camping trip. But with clouds in the sky, there are no stars . . . and no wishes! Button, Dot and Dollop make the most of the night, though — with treats, games and a brand-new friend who happens to glow. Maybe their wish can come true after all?Young readers will be inspired to go on their own nighttime adventure alongside the Funjeepups in this light and funny picture book series by Michael Slack!Series Overview: Join Button, Dot and Dollop on their exciti

My First Paint by Sticker delivers the same screen-free, mess-free fun that makes the original series so irresistible. The fifth book in the series features the cutest mystical mash-ups for the littlest stickerers! You’ve heard of a “unicorn” but how about a “puppicorn”? Or, a “kittycorn?” Kids will adore “painting” scenes featuring these magical creatures and imagining what other types of unicorn friends are out there.The Paint by Sticker Kids® series (for ages 5 and up) has sold more than 10 million copies to date. In My First Paint by Sticker, readers ages 3 and up can confidently paint by sticker, too! At a smaller trim size (8 x 8 inches, versus the original kids brand at 9 x 9), this brand extension features larger stickers for smaller hands—perfect for kids practicing their fine motor skills and learning to recognize their numbers. In the older kids series, the number of stickers per image ranges from 60-100; in My First, the number of stickers ranges from 17-25—an age-appropria

The World’s Greatest Superheroes unite in a dazzling, high-octane adventure that redefines the meaning of “team-up.”Legendary writer Mark Waid and superstar artist Dan Mora bring new energy and heart to the iconic partnership of Batman and Superman in this explosive, critically acclaimed series. Set in a vibrant past of the DC Universe, the Dark Knight and the Man of Steel join forces to face the ancient and dangerous Devil Nezha, a threat powerful enough to require help from unlikely allies such as the Doom Patrol. As the stakes escalate, the World’s Finest must navigate supercharged powers, deadly enemies, and the arrival of a mysterious young hero known as Boy Thunder. Collected in deluxe hardcover for the first time, this edition launches a bold new chapter in superhero storytelling packed with action, emotion, and timeless charm.Collects Detective Comics #1050 and Batman/Superman: World’s Finest #1-11.

Which twin is taller? Sibling rivalry rises to new heights in this funny picture book about two willful and imaginative giraffes. Rafi and Rita are twins. They do everything together. They like the same things, they finish each other's sentences, and they look exactly the same . . . except for their height. But who is the tallest twin, really? Is it Rafi, who's so tall that a painter trying to paint him ran out of paint? Or Rita, so towering in stature that when her hat falls off it takes three hours to hit the ground? In a hilarious progression of hyperbole, Jarvis's narrative, at once humorous and endearing, is matched by Chris Judge's bold and whimsical illustrations in a charming, playful, and oh-so-familiar tale of competitiveness.