Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

From the award-winning author of The Every and the illustrator behind the beloved picture book Her Right Foot comes an endearing and beautifully illustrated story of a dog who unwittingly becomes a hero to a park full of animals.Johannes, a free dog, lives in an urban park by the sea. His job is to be the Eyes—to see everything that happens within the park and report back to the park’s elders, three ancient Bison. His friends—a seagull, a raccoon, a squirrel, and a pelican—work with him as the Assistant Eyes, observing the humans and other animals who share the park and making sure the Equilibrium is in balance. But changes are afoot. More humans, including Trouble Travelers, arrive in the park. A new building, containing mysterious and hypnotic rectangles, goes up. And then there are the goats—an actual boatload of goats—who appear, along with a shocking revelation that changes Johannes’s view of the world.A story about friendship, beauty, liberation, and running very, very fast, The

The second full-color graphic novel adaptation of the blockbuster Warriors series, which has sold more than 66 million copies, covers the third and fourth novels of The Prophecies Begin (Forest of Secrets and Rising Storm). Perfect for attracting new readers and satisfying the legions of Warriors fans!Allegiances are shifting among the Clans of warrior cats that roam the forest. With tensions so delicately balanced, friends can become enemies overnight, and some cats are willing to kill to get what they want. Fireheart is determined to find out the truth about the mysterious death of the former ThunderClan deputy Redtail. But as he searches for answers, he uncovers secrets that might be better left hidden. In the heat of a blazing summer, Fireheart struggles to handle sinister omens, an apprentice with a shocking secret, and a devastated Clan leader who is a shell of her former self. And as the forest gets hotter and hotter, every cat braces for the coming storm....Ever since the first

Carl and Princess Donut refuse to be prey on this level in the USA Today bestselling Dungeon Crawler Carl series by Matt Dinniman--now with bonus material exclusive to this print edition! Attention. Attention. The gates are down. The hunters are loose.Run, Run, Run.A lush jungle teeming with danger. Savage dinosaurs seeking blood. A fallen princess intent on vengeance. A mysterious, end-of-floor celebration for the top crawlers, dubbed "The Butcher's Masquerade." But that's not all. Just when Coast Guard vet Carl and his ex-girlfriend's cat, Princess Donut, think they've seen it all as they compete to survive in the galaxy's most popular game show, the latest dungeon level introduces a terrible new threat. The sixth floor. The Hunting Grounds. As the remaining crawlers battle for their lives, outside tourists are finally allowed to enter the game, and they are ready to hunt. Among them is Vrah, a famed and veteran hunter, intent on collecting the biggest trophy of her career. But her p

●愛爾蘭劇作家 Neil Sharpson 精心打造的搞笑冷知識型繪本，讓大小讀者都會愛不釋手。●《紐約時報》暢銷插畫家、凱迪克獎得主 Dan Santat 生動繪製，每一頁都令人驚嘆！你有沒有發現，魚整天都待在水底下？搞不好牠們在那邊偷偷計畫著什麼也說不定。甚至有「一群魚」的地方竟然被叫作「學校」？牠們到底在學什麼？趕快打開這本繪本查個水落石！不過在調查的過程中請記得，無論發生什麼事，都不要相信魚！這本書由一位超級可疑的敘述者帶你一路吐槽到底，講一堆聽起來好像是真的、卻又讓人狂笑不止的「魚事實」，讀完你可能會懷疑，你家的金魚...真的只是金魚嗎？An absurdly laugh-out-loud funny picture book about the villainy of fish, illustrated by National Book Award-winning creator Dan Santat"A ribald and uproarious warning to those unschooled in fishy goings-on." —Kirkus, starred reviewONE OF SLATE'S 25 GREATEST PICTURE BOOKS OF THE PAST 25 YEARSONE OF BOOKPAGE'S TEN BEST BOOKS OF THE YEARA BEST BOOK OF THE YEAR: New York Magazine, NPR, Chicago Public Library, Smithsonian Magazine, Libby, Kirkus, Publishers Weekly, Publishers Lunch, BookPage, Booklist, School Library Journal, Book Riot, BCCB, Imagination Soup, Parent Map, The Children's Book Review, EBSCO NoveListWhy, dear reader, must you NEVER EVER trust fish?1) They spend all their time in the water where we can’t

故事從一份悄悄留下的手繪地圖集開始：一位即將搬家的孩子，為下一位住進這個家的孩子，細細標記出學校、街道、房間配置與日常風景。這些地圖不只是方向指引，也保存了生活的痕跡——萬聖節裝飾最熱鬧的街角、買麵包與畫畫材料的店、床該放在天窗下的理由。當搬家卡車交錯而過，這本地圖書自然地完成了傳遞。圖像充滿細節，為「離開」與「抵達」同時留下空間，提醒孩子：舊家的記憶與新家的想像，值得同樣被珍惜。A Junior Library Guild Gold Standard SelectionOne of Evanston Public Library's 101 Great Books for KidsOne of Chicago Public Library's Best of the Best BooksA BookPage Best Book of the YearAn NPR "Books We Love" SelectionBefore moving away, a young cartographer leaves some guidance behind about his old home for the child about to make it their new one. What if you moved to a new place and found a hand-drawn local guidebook, left there just for you? In A Book of Maps for You, an artistic young person gives just such a gift. He's crafted and annotated maps of his neighborhood, school, and house; no slide, orange tree, or chicken coop left uncharted. He points out the best Halloween decorations, school lunches, and local stops for baked goods, books, or art supplies. He shows the best place to put yo

本書由 Duncan Beedie 繪製，以誇張又充滿節奏感的圖文，描繪鵝 Hank 的日常小麻煩。Hank 無時無刻都在「HONK！」——看見氣球就想戳破、談話中插嘴、連在圖書館或電影院也忍不住打斷。雖然他覺得好玩，但身邊的人卻愈來愈受不了。於是 Hank 必須面對一個問題：他能學會體貼別人，成為一隻「im-PECK-able」的鵝嗎？本書透過荒誕的幽默與極具戲劇效果的插圖，讓孩子在笑聲中思考「考慮他人感受」的重要性。讀來既搞笑又帶點暖意，很適合與孩子共讀。A honkingly-hilarious tale about the importance of being considerate to others, with stylish illustrations from the super-talented Duncan Beedie (I Really Really Need a Wee, Agent Llama, Heavy Metal Badger). Meet Hank the Goose. He's never met a balloon he didn't pop, or a conversation he didn't - HONK! - interrupt.Hank even honks in the library and during movies! But being this way isn't always fun - and it's upsetting everyone else . . .Maybe it's time for a change? Time for Hank to learn how to be an im-PECK-able goose! Only it's not quite as easy as it looks . . .This hilarious picture book teaches children the importance of being mindful and kind to others. With a loveable anti-hero and told with deadpan humour, fans of Don't Let the Pigeon Drive the Bu

T. Rex is on the building siteand has to smash this wall!He needs someone to SWING their tail . .. just like a WRECKING BALL!There's SO much work to be done on the building site, and the dinos need to find a way to SMASH, SHIFT, MIX and LIFT things quickly before the day is over. By pulling the sliding tabs on each page, little ones can help these busy builders use their special dino skills to transform into construction machines and build something roar-some together .. . Featuring fun dino facts on each slider, a rhyming text perfect for little ones to join in with, and friendly illustrations from Damien Barlow, Busy Builders: Dinos at Work is perfect for children who love dinosaurs and diggers! Ideal for fans of Peekaboo Dinosaur, How Toothy is a T.Rex? and Goodnight, Goodnight, Construction Site.

本書背景設定在 1951 年的倫敦。Clem Fatale 是城裡最年輕的竊賊，她唯一的目標，是找回失蹤的父親——臭名昭彰的珠寶大盜 Jimmy Fatale，同時也是 Spider Gang 的首領。隨著他的消失，倫敦最令人垂涎的寶物「Fool’s Canary」也下落不明。帶著半個人質、半個夥伴的 Gilbert，Clem 展開一場橫跨地下世界的追逐。他們穿梭於破舊酒吧、華麗夜總會、油膩小餐館與隱密巷弄，在朋友與敵人交錯的追捕中，一步步逼近真相。London, 1951: Clem Fatale, the youngest crook in the city, is on a mission to find her dad. Jimmy Fatale, notorious jewel thief and leader of the Spider Gang, has gone missing and with him the greatest prize in London: the Fool's Canary.Along with her prisoner and/or sidekick Gilbert (depends who you're asking), Clem sets off on a rip-roaring chase through the London underworld. Racing through dodgy dives, glamorous nightclubs, greasy spoons and secret alleyways, Clem and Gilbert are soon pursued by a host of friends and foes.Will Clem find her father in time? Or will the most sinister villain this side of the river put a stop to all her plans?A rollicking middle grade series full of madcap escapades, fast-talking dames and unlikely heroes, perfect for fans of MU

Canva 是一款以「簡單易用」為核心的設計工具，從新手到專業人士都能快速上手。它不僅提供豐富的範本與資源，還內建多種AI輔助功能，讓設計變得更加輕鬆。本書正是為了幫助讀者充分發揮Canva的潛力而編寫，無論您是第一次接觸設計，還是希望將設計技能應用到職場或生活中，筆者相信本書都能為您帶來實用的指引與靈感。本書以清晰的架構與循序漸進的方式，從基礎功能的介紹到應用層面的主題實作，力求讓讀者能夠一步步掌握Canva的技巧。

Moving and uplifting, The Restaurant of Lost Recipes features more heartwarming tales from Kyoto’s Kamogawa Food Detectives as they recreate favourite dishes from their customers’ pasts.'Author Hisashi Kashiwai shows a tremendous amount of empathy for his characters as well as a gentle humor. You’ll laugh, you’ll cry, you’ll open a delivery app' - Apple BooksThe Restaurant of Lost Recipes, translated from Japanese by Jesse Kirkwood, is the second book in the bestselling, mouth-watering Japanese sleuthing series for fans of Before the Coffee Gets Cold, and follows on from The Kamogawa Food Detectives. This edition includes an exclusive Author letter.Tucked away down a Kyoto backstreet lies the extraordinary Kamogawa Diner. Running this unique establishment are a father-daughter duo who serve more than just mouth-watering feasts.The pair have reinvented themselves as 'food detectives', offering a service that goes beyond traditional dining. Through their culinary sleuthing, they reconstr

●愛爾蘭劇作家 Neil Sharpson 精心打造的搞笑冷知識型繪本，讓大小讀者都會愛不釋手。●《紐約時報》暢銷插畫家、凱迪克獎得主 Dan Santat 生動繪製，每一頁都令人驚嘆！你有沒有發現，魚整天都待在水底下？搞不好牠們在那邊偷偷計畫著什麼也說不定。甚至有「一群魚」的地方竟然被叫作「學校」？牠們到底在學什麼？趕快打開這本繪本查個水落石！不過在調查的過程中請記得，無論發生什麼事，都不要相信魚！這本書由一位超級可疑的敘述者帶你一路吐槽到底，講一堆聽起來好像是真的、卻又讓人狂笑不止的「魚事實」，讀完你可能會懷疑，你家的金魚...真的只是金魚嗎？A laugh-out-loud picture book all about fish and how we absolutely must not trust them, illustrated by New York Times bestseller and Caldecott Medal-winning Dan Santat.Have you ever noticed that fish spend all of their time under water? What are they plotting down there? And did you know that a group of fish is called a ‘school’? Exactly what are they learning in these ‘schools’? We must find answers. But one thing’s for sure. Whatever you do: Don’t. Trust. Fish.Laugh along as you learn lots of fishy facts from a very suspicious narrator, who believes that there’s something more than a bit fishy about fish… Prepare to laugh, learn, and maybe even look at your pet goldfish a little differently.With deadpan humour f

本書是以 BAFTA 得獎節目 Numberblocks 為基礎設計的官方活動年鑑，內容多達 70 頁，包含遊戲、解謎與故事。孩子可在角色引導下練習數數順序、加減運算、數列規律及形狀辨識，並逐步探索乘除法概念。五大學習層級的設計，讓活動能循序漸進，適合不同程度的孩子操作。書中還加入漫畫式故事，靈感來自節目人氣片段，增添熟悉感與共讀樂趣。插圖鮮明，活動簡單易懂，既能作為課外補充，也能成為日常遊戲的一部分，是一本寓教於樂的數學學習書。Official Numberblocks activity annual, based on the BAFTA-winning CBeebies show!Packed with games, puzzles and stories, this activity book offers over 70 pages of number fun! Plus, enjoy story time together with comic-style stories, inspired by the show's most popular episodes.Focussing on Numberblocks' 5 learning levels and featuring numbers up to 100, the simple activities will help young children learn how to recognise numbers, count in order, add and subtract, recognise and match shapes, understand and complete number patterns, begin to divide and multiply, and develop key maths skills ? all with the help of their Numberblock friends!?5, 4, 3, 2, 1? It's time for some number fun!

各位有寵物的小主人，你們是不是也快滿十歲了？小心！「十歲的生日詛咒」。在迪格比（Digby）的世界裡，每個孩子都知道一個可怕的魔咒：只要主人一滿十歲，心愛的寵物就會神秘消失！眼看生日就要到了，迪格比和他最愛的寵物鼠「巧達」該怎麼辦？別怕！一場讓你心跳加速、腦洞大開的冒險正等著你！迪格比將和他超酷的姊姊莫格（Mog）、還有最好的朋友泰（Tai），一起揭開一個驚天大秘密：所有消失的寵物，其實都去了—Beastopia！什麼是 Beastopia？這是一個充滿魔法奇獸的奇幻世界，你只能用「酷、炫、天馬行空想」來形容！就像暢銷書作家漢娜・高德（Hannah Gold）說的，這根本是「為小小冒險家和動物愛好者量身打造的完美讀物！」為了拯救寵物巧達，三個小英雄必須通過重重考驗，成為「Beastopia」的見習守護者。這本書絕對可以讓所有 7 歲以上的小書蟲都看得目不轉睛！準備好進入一個充滿魔法生物的全新宇宙了嗎？快跟著迪格比一起，踏上這場結合了友誼、勇氣與超萌奇獸的奇幻旅程吧！"Fun, fabulous and full of imagination. The perfect book for young adventure seekers and animal lovers!" Hannah Gold“Beastopia is utterly brilliant, a wonderful magical adventure that’s sure to be a huge hit with kids everywhere!” Andy Shepherd"A rip-roaring adventure." Rachel Chivers KhooStep into a world of magical creatures! Digby, Mog and Tai must pass three challenges to become Apprentice Guardians of Beastopia in this brand-new adventure for 7+ readers.Magical creatures exist. You just need to know where to look...Everybody knows one thing about Dig

A magnificent look at the science of plants from the internationally bestselling and multi award-winning team behind Tiny, Lots and Grow.This tree doesn’t look like it’s doing very much: it just stands there in the sunlight, big and GREEN. But this tree is busy... Starting with the secret workings of a tree, this book transports readers billions of years into the past; back to the moment when plant life first appeared on our planet. Covering its evolution, the steady emergence of fossil fuels and the extraordinary communities of plants around the world today, Nicola Davies and Emily Sutton combine essential biology with a powerful message, calling on readers to celebrate and cherish the most precious colour on Earth: GREEN."Gorgeously illustrated." The Times“A remarkable and very special work of non-fiction.” Independent on Grow

One of Britain's most popular artist presents a brilliantly original format that young children will delight in time and again.It's Mr Wizard's birthday and all of his magical friends have come to visit. Each one has brought him a special present, but what's inside? Open the flap on each spread to unwrap his gifts in one of two different ways that will transform his presents and surprise him with either a lovely treat or a mischievous trick! Will it be a mug that turns into a slug? Or snapping crocs that turn into snazzy socks? With hilarious rhymes to discover inside this innovative new novelty book from Nick Sharratt, this ingenious interactive picture book will have young readers calling out, "Again! Again! Again!"

From the Double Kate Greenaway Medal-winning creator of Small in the City and illustrator of Town Is by the Sea, Footpath Flowers, I Talk Like a River and My Baba's Garden comes a moving look at how memories are made. Tucked up in bed at their new flat, a boy and his mum share memories. Some are idyllic, like a picnic with Dad, but others are more surprising: a fall from a bike into soft piled hay, the smell of an old oil lamp when a rainstorm blew the power out.Now it’s just the two of them, and the house where all of those memories happened is far away. But maybe someday, this will be a favourite memory, too: happy and sad, an end and a beginning intertwined. Do You Remember? is another unforgettable book from award-winning author and illustrator Sydney Smith.

這本 Numberblocks 官方活動年鑑 以孩子熟悉的角色為主角，讓數學學習變得更有趣。書中包含遊戲、謎題和漫畫故事，透過超過 70 頁的活動，引導孩子認識數字、數數順序、加減法、形狀配對與數列規律，並逐步觸及乘除概念。內容依五大學習階段設計，循序漸進，幫助孩子培養專注力與邏輯思考。漫畫風格的故事則增添親切與趣味，適合家庭共讀。這是一本能讓孩子在遊戲與故事中自然累積數學基礎的讀物，兼具啟發性與娛樂性。Official Numberblocks activity annual, based on the BAFTA-winning CBeebies show!Packed with games, puzzles and stories, this activity book offers over 70 pages of number fun! Plus, enjoy story time together with comic-style stories, inspired by the show's most popular episodes.Focussing on Numberblocks' 5 learning levels and featuring numbers up to 100, the simple activities will help young children learn how to recognise numbers, count in order, add and subtract, recognise and match shapes, understand and complete number patterns, begin to divide and multiply, and develop key maths skills ? all with the help of their Numberblock friends!?5, 4, 3, 2, 1? It's time for some number fun!

Tired of chopping fruit, cubing cheese, fishing rice cakes out of a backpack and generally fielding incessant snack requests? Then Snack, Please! is the book for you – all about the joy of making and sharing food, together!"A satisfyingly conveyed and empowering message about choosing what to eat." Kirkus Reviews"Charming." BooklistGertie LOVES snacks: sofa snacks, bath snacks, bedtime snacks … it’s a snack life! She abandons almost every mealtime in favour of snacking. Her daddy can’t help but feel frustrated – how can he convince her to try new food? Or to even talk about something other than snacks? A day in Granny's allotment might just provide all the inspiration that's needed. In this funny, warm companion title to Carry Me!, Georgie Birkett explores small children’s exasperating eating habits and, once more, through a very endearing father-daughter mouse duo, she perfectly captures the ups and downs of parenting life.Look out for more Cheery Street titles that parents and kids l

十二歲的 Ciara 住在一個禁止魔法的小村莊，卻意外念出一段古老咒語，召喚出一隻真正的龍──還是脾氣不太好的那種。這隻名叫 Scorch 的龍，似乎知道許多失傳的魔法知識，甚至願意幫她拯救被帝國關押的母親。Spellbinders: The Not-So-Chosen One 用跳脫常規的旁白、滿滿笑點與冒險場景，帶出一段關於勇氣、友情與顛覆命運的旅程，是喜歡幽默奇幻的讀者不可錯過的新選擇。In this hilarious fantasy adventure from the New York Times bestselling author of the Story Thieves series, a girl strikes a deal with the ancient, cranky dragon she accidentally summoned to teach her the forbidden magic she needs to save her mother. STOP. Don't read any further. There are magic spells in this book, and the Emperor has forbidden anyone from learning magic, because it's way too dangerous! If you try one of the spells, any number of terrible things might happen (or so the Emperor says). Don't be like Ciara, a twelve-year-old girl living in the tiny village of Skael. When she used a spell from within this book, she ended up summoning a dragon. A DRAGON! Those things breathe fire! From their mouths! She's obviously doomed. And don't listen if Ciara tells you that dragons won't h

Join Liko and Roy, the new protagonists of Pok幦on animation, in an action-packed illustrated chapter book!The new Pok幦on Trainers are here! Join Liko, Roy, and their friends and Pok幦on pals as they sail toward adventure on an airship steered by Captain Pikachu! They work to discover the mysteries of Pok幦on--as well as the mysteries of a special pendant Liko was given by her grandmother, which seems to hold great power. Get ready for the start of something big!This is the first chapter book debuting the new Trainers and First Partner Pok幦on! Adapted from episodes of the new Pok幦on Horizons animated series that launches in March 2024, with black-and-white illustrations throughout.

What happened last night? Ella can't seem to remember a single thing from the party the night before at a stranger's mansion, and she sure as heck doesn't know why she's woken up in her bed surrounded by a magpie's nest of objects that aren't her own. And she can't stop thinking about her huge crush on Madeline, who she definitely can't tell about her sudden penchant for kleptomania . . . But does Maddy have secrets of her own? Can they piece together that night between them and fix the mess of their chaotic personal lives in time to form a normal, teenage relationship? That would be nice.

★ 一個混亂的夏天，一段關於愛的練習★ 幽默與孤單交織，寫出成長最真實的樣子★ Kate DiCamillo最溫柔也最深刻的作品之一那個夏天，事情一件接著一件發生。妹妹突然決定成為壞人，叔叔搬進地下室畫一幅永遠畫不完的畫，而奶奶開始在門口看見一個幽靈——不是帶走她的那種，而是似乎還有話要說的幽靈。費里絲站在這一切之中，看著世界變得有點荒謬，也有點不可思議。她慢慢明白，所謂的成長，不只是離開童年，而是學會在混亂中看見彼此，在不完美裡理解愛。"DiCamillo's gift for conveying an entire person and world in a few brushstrokes of storytelling provides depth and quiet magic to this account of an eventful summer. . . . Tenderly resonant and memorable." --Kirkus Reviews (starred review) It's the summer before fifth grade, and for Ferris Wilkey, it is a summer of sheer pandemonium: Her little sister, Pinky, has vowed to become an outlaw. Uncle Ted has left Aunt Shirley and, to Ferris's mother's chagrin, is holed up in the Wilkey basement to paint a history of the world. And Charisse, Ferris's grandmother, has started seeing a ghost at the threshold of her room, which seems like an alarming omen given that she is also feeling unwell. But the ghost is not there to usher Charisse to the Great Beyond. Rather, she has ot

在母親過世後，11歲的 Adara 跟著爸爸搬到遙遠寒冷的密西根。她不知如何與父親談話，心裡空蕩蕩的，就像那些不再被澆水的植物。某天，她意外發現自己能與一株名叫 Perle 的多肉植物溝通，開啟了一段既魔幻又療癒的對話旅程。《How to Talk to Your Succulent》以鮮明飽滿的色彩與充滿情感的圖像，描繪出面對失落時的孤單、成長與重建。故事細膩動人，讓讀者感受到傾聽與表達的力量，也提醒我們：即使難以說出口，情感仍能找到自己的出口。A School Library Journal Exceptional Graphic Novel & Manga Title for All AgesAfter the loss of her mother, Adara struggles to communicate with her family about her grief. When a sympathetic ear arises in an unlikely place, Adara can finally find her words — but can she find the time to listen? A stunning graphic novel for middle-grade readers about family, friendship and magic in unlikely places, for fans of The Witches of Brooklyn and Raina Telgemeier.Eleven-year-old Adara and her dad are moving from California to the cold and flat lands of Michigan . . . and it sucks. After Mom's recent passing, it seems way too soon. Talking to Dad has always been harder than with Mom, but now it's like walking on eggshells. And why did Dad bring so many of Mom's houseplant

“This story was everything I wanted it to be. Heartfelt, thoughtful, and most of all . . . full of hope. I loved it!”—Lindsay Currie,New York Timesbestselling author ofThe Mystery of Locked RoomsConnor, beloved best friend of Aven Green fromInsignificant Events in the Life of a Cactus, tells his own story in this poignant and heartwarming tale about overcoming the challenges of life with Tourette’s.Connor Bradley is dreading the first day of high school. Not just because he is new, or because he misses his best friends, but because he knows the other kids won’t understand his barking and tics. Connor has Tourette Syndrome, and every day has been a challenge—from the mimicking to the laughing, the questions, and the stares. It turns out school isn’t quite as bad as he expected. Connor forms a fast friendship with a girl who also has Tourette’s and is welcomed into her accepting circle of friends. He also meets a special music teacher who encourages him to take up the drums to manage his

Avery stumbles into a magical circle transporting her to a wonderous fairy world. Avery's family has just moved to the Pacific Northwest countryside. She explores the forests outside her home and in the woods she stumbles into a magic fairy circle which shrinks her. A young fairy named Birch agrees to help her reverse the magic on the condition she helps with plant gathering duties for the imminent full moon festival. She must befriend Birch and find the fairy village quickly if she wants to return home before her parents discover she is missing.

What happens when a new baby moves in--and the doted-on "older sibling" is a pampered pooch? People stop to say, "Oh, what a cutie patootie baby!" What? Is it not clear? I am the patootie. Follow the adorable puppy Hazel through a typical day at home, where she rules the roost. Check out the dozens of toys, the nifty stroller, the comfy places to take her (many) naps, the various tasty snacks, and most of all, lots of quality time with her girl, Bea. Together, Hazel and Bea are sensational. Until the baby arrives, that is, and everything changes. Now Hazel isn't always the center of attention--even Nana barely has time for a cuddle. Things have gone too far! But when Hazel runs off to hide, the family is desperate to find her, and Hazel is reminded just how much she is loved. In this endearing comedy for dog lovers and expanding families from a stellar creative team, there's room for everyone in the hug circle--and messy new arrivals who drop enticing crumbs turn out to be not so bad a

在「傳統」與「變新」之中取得平衡佛法的實踐方法如何與時俱進？聖嚴法師為使佛法能適應現代需求和變化，推動心靈環保、心五四、心六倫等運動為當代幸福生活指南，指引全人類可長可久的共榮願景方向。第九屆漢傳佛教與聖嚴思想國際學術研討會，廣邀各界學者進行對話，探討佛法的生活實踐，透過跨領域的多樣研究，討論佛法如何為當代社會注入活水。共有四大主題：▍聖嚴法師的思想與實踐▍心靈環保與社會實踐▍漢傳佛教四百年▍佛教論典的形成、注疏與傳播● 本書精選研討會九篇論文：一、聖嚴法師默照禪法禪修次第建構歷程初探／釋果幸 二、消費與可持續性發展——探討聖嚴法師「心靈環保」對當代可持續性發展與經濟生活之意義／許永河 三、當佛法遇到經濟學——用「心」對話與了解／江靜儀四、企業領導人應用佛法之企業文化與社會影響力／陳定銘、蔡康正、鄭逢緯五、兒童宗教參與對父母宗教親職的影響——以法鼓山悟寶兒童營為例／釋演本六、法鼓山僧團瑜伽焰口施食儀之傳承發展研究／陳省身七、從自我到他者——聖嚴法師宗教交流與對話之典範／劉韋廷八、A Transnational Comparative Study of Fasting and Monetary Precepts in Contemporary Chinese Buddhism:Taiwan, Mainland China, Myanmar, and Thailand／Tzu-Lung Chiu 九、清虛休靜儒佛會通論的特點及意義——以〈儒家龜鑑〉為主／任洧廷

序言 《圖解醫學統計學》是專為醫學系學生、醫學研究人員、生物醫學領域的研究生以及醫藥從業人員而設計。這些人在其職業生涯中有時會碰到量化的數據結果（自己或他人的），需要嚴謹的評估與解釋，其中有些還需要通過可怕的統計考試！針對這些需求，重要的是要理解正確的統計概念和方法。我們很務實的，希望燃起讀者對統計的熱情。如同前一個版本，本版的目標，是提供處理醫學文獻統計概念的學生、研究人員和臨床工作者，一本內容嚴謹、易於閱讀、具全面性、切合主題且實用的應用書籍。我們相信《圖解醫學統計學》會是一本特別有用的統計課程參考指南。第 四 版 的 架構， 與 前 三 版 相 同。 如 同「at a Glance」系列的其他書一樣，藉由兩到三頁，或是四頁的章節引導讀者，每個章節分別說明醫學統計學的不同面向。文中有大量的交叉應用，方便讀者在不同的過程做連結。我們從自己的教學經驗中汲取了寶貴的見解，並考慮學生學習醫學統計時遇過的困難。基於此，我們選擇將書中的理論內容控制在足以理解相關統計方法的範圍內，以確保理論不會掩蓋其實際應用的可行性。醫學統計學是一門包含許多主題，內容廣泛的學科。本書提供基本概念的入門介紹，以及常用的統計方法。流行病學，是門研究特定人口疾病的分布和起因的學科，與醫學統計學有緊密的關聯。因此，會討論到流行病學中關於實驗設計和解釋的主要議題。有些章節，偶爾才會使用，但卻是許多醫學研究領域中的基礎，像是實證醫學、系統回顧、統合分析、存活分析、貝氏方法，以及建立預後評分。我們講解了這些章節的原理，讓讀者看到相關文獻時，能夠看懂且能判讀其結果。附錄 A 中，有許多基本的統計表。例如，Neave, H R (1995) 統 計 表 格，Routledg: 倫 敦 和 Diem, K , Lenter, C , 及 Seldrup (1981) 的 Geigy 科學表格第 8 版的文獻及書目檔案，Basle: Ciba-Geigy 及其他人的更完整版本，可提供讀者需要更精確的手算結果時使用。第四版中，新增了附錄 D。這個附錄包含隨機對照試驗（CONSORT 檢核清單和流程圖）和觀察型研究 （STROBE 檢核清單）的指引。CONSORT 和 STROBE檢核清單是由 EQUATOR Network 製成，初始目標在於提供健康研究的資源和訓練。研究結果的呈現指引已經用於許多其他類型的研究，我

**《小巫師 Gumluck》——最搞笑的魔法冒險來了！** 🔮 **魔法 × 鬼魂 × 英雄夢，一場顛覆想像的奇幻旅程！** Gumluck 是個住在大山裡的迷糊小巫師，他夢想成為英雄，卻總是陰錯陽差！這次，他將與 **失憶鬼魂、不受歡迎的仙子、毒舌烏鴉** 一起對抗一座忘恩負義的小鎮，迎接最荒誕又感人的挑戰！ ✨ **簡單幽默 × 插畫豐富 × 適合新手閱讀的魔法冒險** 🔥 **「可愛又爆笑！」——Kirkus Reviews 五星好評**The acclaimed chapter book is now in paperback! Meet Gumluck, everyone’s favorite wizard, in this delightfully silly series by New York Times bestselling author Adam Rex. A Kirkus Reviews Best Picture Book of 2023 A 2023 Chicago Public Library Best of the Best Book FIVE STARRED REVIEWS! "Adorable."—Shelf Awareness, starred review"Readers will fall in love with [Gumluck]."—School Library Journal, starred review "Silly and heartfelt."—Publishers Weekly, starred review"[A] spellbinding read."—Booklist, starred review"Here's a tale to treasure."—Kirkus Reviews, starred reviewThis is a story about magic, if you like that kind of thing. It is also a story about a ghost with amnesia, an unpopular fairy, an ungrateful little town, and

載著自信獨自飛行的小飛機，卻磕磕碰碰弄得灰頭土臉！繪本大師五味太郎帶領孩子體驗跌跌撞撞的成長，在挫折中持續的茁壯，並感受親子間珍貴的信任，與探索廣闊世界的自由！★ 精選大師經典繪本，與孩子一起面對挑戰，在閱讀中促進語言與認知發展，增進親子情感。★ 精心錄製中、英文繪本故事音檔，掃描書中的 QR Code 即可隨時聆聽，營造雙語學習與對話的氛圍。 小飛機精神飽滿的出門了，小心喔！ A little plane is heading out in high spirits. Be careful! 嗨！小飛機飛起來了，小心喔！ Hey! The little plane is flying! Be careful! 天氣真好呢！小心喔！ It's a beautiful day. Be careful! 前方有煙囱，小心喔！ There are chimneys up ahead. Be careful! 啊！小飛機被燻得髒兮兮的。 Ah! The little plane got a little smoky. 小飛機要挑戰獨自飛行，他辦得到嗎？ 一開始狀況很不錯喔！天氣很好，飛行途中遇到的每個朋友，都親切的叮嚀小飛機「小心喔！」。 直到前方出現兩支煙囪，來不及飛更高的小飛機穿過了灰煙，變得髒兮兮；接著遇到一大片樹林，來不及飛更高更高的小飛機，撞到了樹頂；後來出現一座山，來不及飛更高更高更高的小飛機，撞到了山頂，這下子不只灰頭土臉，還鼻青臉腫了呢！ 小飛機最後飛進一棟建築物裡，雖然大家還是提醒他「小心喔！」，但仍然忍不住為小飛機擔心，沒想到小飛機從那棟建築物飛出來之後，變得乾乾淨淨，好像沒發生過任何事一樣。 那棟神奇的建築物裡，到底有什麼呢？當小飛機再次出發飛行時，你會信任他所做的一切嗎？ 親子共讀時，家長可以先講幾遍故事，或掃描QR Code播放音檔讓孩子聆聽，不管中文版或英文版的故事，都會出現這本書的關鍵句「小心喔！」(Be careful!)，當孩子剛開始學說話時，家長可以把說關鍵句的重要任務交給孩子，讓孩子展現對小飛機的溫柔守護；等到孩子語言能力發展更好時，就可以讓孩子嘗試說出故事中的語句，如「前面有……」(There’s a … up ahead.)，然後把「小心喔！」(Be careful!) 的關鍵語句交給家長，這次就換家

小心翼翼的行駛在茫茫大海，小輪船努力繃緊神經直到最後！繪本大師五味太郎陪伴孩子在一次次冒險中堆疊勇氣，慢慢的學會如何保護自己，並傳遞家人無聲的愛與支持，始終是可以依靠的安穩港灣！★ 精選大師經典繪本，與孩子一起面對挑戰，在閱讀中促進語言與認知發展，增進親子情感。★ 精心錄製中、英文繪本故事音檔，掃描書中的 QR Code 即可隨時聆聽，營造雙語學習與對話的氛圍。 小心不要擋到別人喔！ Be careful not to get in the way. 小心不要撞到別人喔！ Be careful not to bump into anyone. 小心不要嚇到別人喔！ Be careful not to startle anyone. 小心不要搖晃得太厲害喔！ Be careful not to wobble too much. 小心不要翻覆喔！ Be careful not to tip over. 在來來去去的碼頭，小輪船要出發去航行了！ 一路上，小輪船不停的嘗試避開周遭的船，小心不要擋到別人，也不要撞到別人，即使遇到了嚇人的大郵輪，只要想辦法繞過他就好，也希望大郵輪不要嚇到獨自努力前進的小輪船，可是航行在大海上才沒有這麼簡單呢！遠離了大大小小的船後，波濤起伏的海浪，才是讓人煩惱的問題，該怎麼樣保持平衡，不要搖晃得太厲害，更不能翻覆了，浪潮不斷襲來的難關一再考驗著初出茅廬的小輪船。 接著，又遇到刺眼的太陽、烏雲和下雨天，小輪船都鼓起勇氣一一克服了，但他的旅程還沒結束，凡事都要小心喔！可是，周遭的海洋已經沒有任何船，也沒有驚濤駭浪，連太陽、烏雲都被他拋在身後了，他還要小心什麼呢？ 原來要小心不要感到孤單，也要小心別讓愛你的人等太久，不要太晚回家喔！ 這次，一直被叮嚀要小心的小輪船，也想撒嬌的說，小心不要只會說「小心」喔！爸爸媽媽你們也要小心，小心不要忘了接我回家。整趟航行都在提心吊膽，現在有大輪船在身邊，終於可以安心的瞇起眼睛了！ 親子共讀時，家長可以先講幾遍故事，或掃描QR Code播放音檔讓孩子聆聽，不管中文版或英文版的故事，都會出現這本書的關鍵句「小心不要……」(Be careful not to…)，當孩子剛開始學說話時，家長可以把說關鍵句的重要任務交給孩子，讓孩子給小輪船滿滿的勇氣；等到孩子語言能力發展更好時，就可以讓孩子嘗

本書以幽默漫畫結合知識圖解，帶領8歲以上讀者探索生物、化學、物理、地球與太空，以及元素週期表等科學主題。每個跨頁皆有一則輕鬆有趣的漫畫情節，搭配簡潔明瞭的解說與插圖，將抽象概念轉化為貼近生活的情境，提升學習興趣。插畫家 Jess Bradey 曾獲 2021 年 Blue Peter 最佳非虛構作品獎，圖像生動、節奏俐落，讓科學變得親近可笑又可學。此系列適合作為課外延伸閱讀，也能啟發科學探究的好奇心。📖 亮點特色★ 漫畫＋知識圖解，學習更生動★ 主題涵蓋自然科學五大領域★ Blue Peter 獎得主繪者創作★ 適合8歲以上自主或共讀Comic Strip Biology makes learning about the science behind animals, plants and the human body fun!Each spread in this series features a short, funny comic strip that explains a process or aspect of science. Around the strip, diagrams and panels give further information on the topic. They are a fantastic way to engage children aged 8 plus with science.The illustrator, Jess Bradey, is winner of the 2021 Blue Peter Award for Best Non-Fiction for A Day in the Life of a Poo, Gnu and You and also writes and draws for The Phoneix comic.Titles in the series: Biology, Chemistry, Earth and Space, Physics.此套書包含以下商品9781526319999/Comic Strip Science: BiologyFind out about the science of living things through hilarious cartoon strip

「英國人很常這樣說，外國人卻不知道！」從打招呼、約見面、表達關心、抱怨、談工作，到聊天氣最貼近生活、適用不同情境的800句對話讓你用英式風格接住日常話題，自然地融入當地生活！ 用英文聊天的時候，是不是表達總是差那麼一點？？ 明明語意沒有錯，話題卻一下子就結束？ 關鍵在於，你不知道英文母語者都怎麼聊！ 聊天就像拋接球，如果不能自然接住話題，對話就會像失手的球一樣尷尬落地。要在英文對話中接住話題，就得了解母語者都怎麼說！ 舉例來說： 有人分享自己做了厲害的事，你可以立刻誇獎Nice one!（幹得好！）；要表達理解，除了說I get it.，還可以說Fair enough.（聽起來很合理。）；朋友講了很扯的經驗，你可以說That’s mad!（太誇張了！）；聽到有人分享衰事，可以說That’s the pits.（太糟了吧。） 在聊天中給予適當的回饋，就能讓氣氛更加熱絡；掌握英國人慣用的說法、口吻，就能聽懂言下之意，讓對話流暢進行，即使身為外國人也不會格格不入！ 本書作者在倫敦生活6年，深入觀察英國人在日常和職場中的對話，精選出800句連英國人都認可、實用度最高的說法。例如： A：What are your plans for tomorrow?（你明天有什麼計畫？） B：Just chilling out.（在家耍廢。） 此外，各種說法的使用範例中，時不時會出現神來一筆的英式幽默，除了學英文用法，也體會整個文化中的機智詼諧，例如： A：Last night I was so upset we lost the match. I indulged in a big box of chocolates.（昨晚我因為比賽輸了心情好差，所以嗑掉一大盒巧克力。） B：How are you feeling today?（那你今天覺得如何？） A：Fat.（覺得胖。） 全書輕鬆有趣，書中解說不同說法的起源、適用的情境，還不時補充英國文化小知識，讓讀者豐富學習，深刻感受英式英語獨特的魅力！ 適用讀者 如果你…… ■ 即將前往英國求學、工作 ■ 喜歡英國影視作品 ■ 熱愛英國文化 那麼一定不能錯過這本書！ MP3免費聆聽 讀者請參閱書內APP操作說明，或加入眾文LINE官方帳號好友（ID：@jwbooks）申請兌換序號，享有免費聆聽音檔的

在冰封的世界裡，唯一能感受溫暖的地方，是被巨大圓頂覆蓋的「雪球城」。城內居民享有名聲、財富與安全，代價是他們的生活被24小時直播，供外面的貧困者觀看。來自外界的少女初凡，夢想進入雪球城，卻意外被選為城內明星的替身，才發現一切與螢幕上截然不同……韓國話題小說《Snowglobe》，首次推出英文版，揭開虛假之下的真相。“The Hunger Games meets Squid Game.” – Entertainment WeeklyIn a world of constant winter, only the citizens of the climate-controlled city of Snowglobe can escape the bitter cold—but this perfect society is hiding dark and dangerous secrets within its frozen heart. The groundbreaking Korean novel translated into English for the first time, now in paperback!Raised in a climate-ravaged, frozen world, every day is a struggle for survival for Chobahm. Her only solace comes in the form of twenty-four-hour reality television, streamed directly from Snowglobe--the climate-controlled domed city at the heart of her world, and the only warm place left on the planet.But her life changes in an instant when she's visitied by two strangers from Snowglobe, who deliver earth-shattering news: Snowglobe's bigest star has died--and because of Chobah

Jack 和 Annie 的首次魔法之旅帶他們回到恐龍時代，滿腦子都是問題：恐龍住在哪？吃什麼？為什麼會消失？一起以圖像小說的形式揭開恐龍世界的神祕面紗！結合生動畫面與真實科學的知識冒險之書。When Jack and Annie got back from their adventure in Magic Tree House #1: Dinosaurs Before Dark, they had lots of questions about dinosaurs. Learn more along with them as they track the facts about these amazing prehistoric creatures--available for the first time ever in a nonfiction graphic novel format!Filled with up-to-date information and fun tidbits from Jack and Annie, the Magic Tree House Fact Tracker Graphic Novels are the perfect way for kids to find out more about the topics they discovered in their favorite Magic Tree House adventures!Find out the answers to things like: What did dinosaurs looked like? Where did they live? How did they survive? What’s the difference between flesh-eaters and plant-eaters? And, of course, how did the dinosaurs die? There’s so much to learn, so come along on this prehistoric adventure with Jack and Annie as they investigate and discover the dinosaur

日本棒球好手大谷翔平，以投打「二刀流」技術聞名世界。他曾帶領日本火腿隊奪下2016年日本大賽冠軍，之後加盟美國大聯盟天使隊，並於2018年獲選美聯最佳新人。2021年，他創下全壘打、盜壘與三振三項數據超越歷史紀錄，更榮獲美聯MVP。本書帶領讀者認識這位傳奇球星的成長與精彩表現。Learn about Japanese baseball player Shohei Ohtani and what makes him one of the greatest players of all time!Shohei Ohtani, also known as "Shotime," is widely known for his skills in both pitching and hitting. At the 2016 Japan Series, Ohtani led his team, the Fighters, to victory. He later signed to the Los Angeles Angels in 2017 and earned the title of American League Rookie of the Year in 2018. In 2021, Ohtani made Major League Baseball history with over ten homeruns, over twenty stolen bases, and over one hundred strikeouts. That same year, at only age twenty-seven, he was given the American League Most Valuable Player Award. Young readers will learn about the life and athletic achievements of one of baseball's most iconic players.Series Overview: Who HQ Now retains all the best and beloved features of the Who Was? series at a lower page count

Tanjiro and the rest of the Demon Slayer Corps are back and facing their greatest challenge yet: school life! Welcome to Kimetsu Academy, a school attended by the most exceptional students you've ever seen! This comedic spin-off of international smash hit Demon Slayer: Kimetsu no Yaiba pits Tanjiro, Nezuko, and all the rest of the Demon Slayer Corps against the trials and tribulations of student life. Spring is here, and life is in full bloom at Kimetsu Academy! A poorly placed cut (on a pizza) gets Muichiro into a world of trouble with his brother, while Rengoku's dad stumbles into a real bear of a battle. Meanwhile, Uzui finds himself wrapped into an artistic showdown with the (literal) demons of Kimetsu Academy. And that's not even mentioning the fashion, the fireworks, or the fishing!

Meet Mirabelle Starspell. Her mum is a witch, her dad is a fairy and she is a bit of both. She likes casting spells with her fairy wand and flying around on her witchy broomstick, but most of all the thing she really, really likes to do is cause mischief.When Mirabelle and her family are invited to spend some time at a dragon sanctuary, Mirabelle cannot wait to get stuck in and show off everything she knows. But she's about to find out that she's not quite the dragon expert she believes herself to be . .

Meet the friendly faces and mobs of A Minecraft Movie in this adventure for young, struggling or reluctant readers and kids who love video games!If you enjoyed A Minecraft Movie, you’ll love this book! Welcome to the world of Minecraft, where creativity doesn’t just help you craft, it’s essential to survival!Four misfits – Garrett ‘The Garbage Man’ Garrison, Henry, Natalie and Dawn – find themselves pulled through a mysterious portal into the Overworld: a bizarre, cubic wonderland that thrives on imagination.To get back home, they’ll have to master this world (and protect it from evil things like Piglins and Zombies, too) while embarking on a magical quest with an unexpected, expert crafter, Steve. Together, their adventure will challenge all five to be bold and to reconnect with the qualities that make each of them uniquely creative … the very skills they need to thrive back in the real world!

Even the things that go bump in the night must go to sleep in this bedtime tale perfect for fans of Adam Rubin and Aaron Reynolds!All creatures grim and evil,under the tired sun,are settling down—and so must you,my horrible little one...It's time to go to bed, and whether you are a werewolf, vampire, dark lord, or yeti, you still must brush your teeth, put on your pajamas, and settle downwith a cozy story. Full of warmth and humor (and slime), this rhyming bedtime bookwill disgust and delight sleepy little monsters everywhere.