Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

New York Times bestselling authors Becky Albertalli and Adam Silvera join forces in this critically-acclaimed stand-alone rom-com about two very different boys who can’t decide if the universe is push

A charming introduction to simple money concepts in which a little bunny learns about the power and satisfaction that come with saving money.Honey earns two carrots a week for taking care of her sibli

Newbery Honor author Renée Watson explores a family’s relationships and Harlem—its history, culture, arts, and people.All Amara wants is to visit her father's family in Harlem. Her wish comes true whe

When witches kidnap her dad, Mup is swept up in a wild tide of magic that carries her to another world. Can she reunite her family and find her way back?On the night that Aunty dies, the raggedy witch

A reissue of Wattpad's most loved story with over 26 million views!Jackie’s goal is perfection—perfect grades, the perfect look, getting into the perfect school. If she can achieve that, then maybe her too-busy mom and dad will take notice. But when her parents die in a tragic accident, Jackie is shipped off across the country to live with the Walters, her new guardians…who just happen to have twelve sons (well, eleven, but their daughter, Parker, is basically one of the boys).The Walter boys are loud, dirty, annoying—and, okay, some of the older boys might be Greek god level hot, but they don’t think a city girl belongs on their horse ranch. How is Jackie supposed to fit into their chaotic world when she needs to keep her parents’ memory alive by living up to the promise of perfect?But as Jackie spends more time the Walter boys, she begins to wonder if the perfection she’s always worked for isn’t the only way to find love after all.

The Ultimate Spotlight books have all the fun, facts, and hands-on action of the fabulously successful Ultimate series, but in a focused, more-compact, and affordable format. Flaps, pull tabs, and man

Read along in these three new readers as Alice searches for a Christmas gift for the Queen of Hearts, Figaro creates a little Christmas chaos, and Scrooge McDuck learns the meaning of the holiday. Acc

Heidi’s school is having a school spirit week in the twenty-seventh Heidi Heckelbeck adventure!It’s Spirit Week at Brewster Elementary and everyone is excited! From Crazy Hair Monday to Wacky Tacky We

Every day in Mr. Wolf's class is an adventure... even when you have to stay home from school!Mr. Wolf's students are having a "writer's workshop" and are learning about personal narratives. Sampson do

On the night Brian Bishop murdered his wife he was 60 miles away, asleep. At least that's the way it looks to Detective Superintendent Roy Grace, who is called in to investigate the kinky slaying

Scout and Daisy are on expedition in the desert and Scout has uncovered something incredible -- a rock has told him a story! But how can a rock tell a story? Join Scout as he helps Daisy find clues to solve the Case of the Story Rock.Titles in The Gumboot Kids series:The Case of the Buzzing Honey Makers (9780228102816, paperback, 6.99)The Case of the Buzzing Honey Makers (9780228102823, hardcover, 19.95)The Case of the Singing Ocean (9780228102847, paperback, 6.99)The Case of the Singing Ocean (9780228102854, hardcover, 19.95)The Case of the Growing Bird Feeder (9780228101901, paperback, 6.99)The Case of the Growing Bird Feeder (9780228101895, hardcover, 19.95)The Case of the Story Rock (9780228101925, paperback, 6.99)The Case of the Story Rock (9780228101918, hardcover, 19.95)The Case of the Vanishing Caterpillar (9780228101949, paperback, 6.99)The Case of the Vanishing Caterpillar (9780228101932, hardcover, 19.95)The Case of the Wooden Timekeeper (9780228101963, paperback, 6.99)The C

Tania "Thumbelina" Pulgar may be small, but she's fierce in the wrestling ring. When her friend Jorge “The Mouse” Mendoza introduces her to a manager named Mr. Mole, she’s promised a pro career full o

Anna is a shy, booking-loving girl whose only friends are the characters in her books, but when Grandpa suggests she go outside to play, Anna has trouble talking to the other children. That is until she meets a boy who wants to find a cat named Mr. Robinson. A sweet story about a friendship between two shy, reserved children.

勞倫斯畢生以四海為家。青年時代剛踏入文壇，他就曾與情人私奔歐洲大陸，徜徉山水之際，尋找優游自在之鄉。其間，與意大利結下不解之緣。本書從他撰於青年時期的第一部、也是最知名的遊記《意大利的黃昏》（Twilight in Italy）中精選了三篇：〈加爾達湖的檸檬園〉、〈漂泊的異鄉人〉、〈歸途〉，內裏記錄了他1912-1916年間從奧地利、德國、瑞士等地徒步往意大利旅行時的見聞與反省。勞倫斯對當地風土人

全球熱銷超過百萬冊，超過25種語言翻譯出版壞蛋也想當好人！一隻狼、鯊魚、食人魚和一條蛇，全世界公認的壞蛋們，下定決心要做好事、當好人。雖然兇惡的外表老是害他們被誤會，他們還是一次次聯手出擊，搞笑出任務，力求改變形象！此套書包含以下集數：Episode #1: The Bad Guys (9789810986988)Episode #2: The Bad Guys in Mission Unpluc

The Bad Guys are back for the 9th installment of the New York Times bestselling series! When Mr. Wolf is blown up to Godzilla proportions, the Bad Guys find themselves in monster-sized trouble. They m

Medical Negligence in Hong Kong and How to Avoid It provides essential information concerning the potential legal liabilities that medical professionals face when they treat patients. An easy-to-read

In 648 CE, Tang imperial authorities collected every copy of the Writ of the Three Sovereigns (Sanhuang wen) from the four corners of the empire and burned them. The formidable talismans at its core w

It's springtime in this charming, busy town and there is a lot going on! A house gets a top-to-bottom spring cleaning and farm fields are being prepared for planting. People are shopping, commuting to work, constructing buildings, and meeting friends. If you look closer, you'll recognize the same characters appear on every page, each with their own story. There's Wilfred the jogger slipping on a banana peel and his friend Erica who comes to help him. Three cheerful nuns shop, chat, and share a snack at the cafe. A stork surveys all the activity from the sky while a mischievous fox scampers through the streets. In the tradition of Richard Scarry and Where's Waldo, this book encourages kids to return again and again to each spread, following along with the characters and inventing their own stories. They'll recognize parts of their own world, while also learning about the endless ways we live, work, and play in the spring.

The 117-Storey Treehouse is the ninth book in Andy Griffiths and Terry Denton's wacky treehouse adventure series, with the laugh-out-loud story told through a combination of text and fantastic cartoon

A breathtaking picture book about the water cycle from Kate Greenaway Medal winner Grahame Baker-SmithIssac plays in his favorite pool on the mountainside. As rain starts to fall, he empties his littl

In this illustrated chapter book retelling of a folk tale from Cambodia, cunning Dara uses her expertise as an engineer to foil a wicked plot and save her husband. Available individually and as part o

故事結合古老瑪雅神話，描寫一名行動不便的男孩，如何在命運逼近時找到屬於自己的位置。拄著拐杖的贊恩原本只想避開校園裡的嘲笑，卻在火山深處發現通往神界的門。新同學布魯克斯的出現，讓他逐步理解預言的真意，也迫使他面對父親身世與諸神之戰。對喜愛 Percy Jackson and the Olympians 的讀者而言，本書提供了熟悉卻嶄新的閱讀體驗。Best-selling author Rick Riordan presents J.C. Cervantes' take on Maya mythology featuring a boy who has to stop the god of death. "A perfect storm of inspiring heroes, surprising twists, and some seriously scary monsters. This hilarious, expertly-plotted adventure keeps you racing through the pages and leaves you desperate for the next book (and craving a steaming mug of hot chocolate)!" --Shannon Messenger, New York Times best-selling author of the Keeper of the Lost Cities series and the Sky Fall seriesA contemporary adventure based on Maya mythology from Rick Riordan Presents!Zane has always enjoyed exploring the dormant volcano near his home in New Mexico, even though hiking it is challenging. He'd much rather hang out there with his dog, Rosie, than go to middle school, where kids call him Sir Limps a Lot, McG

Sing around the world, from mountains to valleys, in towns and cities, with all the fish, birds, trees and flowers of the Earth! Adapted from the popular spirituals song, and with helpful endnotes, th

The author of The Big F is back with another snappy, utterly relatable contemporary young adult novel about loving yourself and forging your own path, perfect for fans of Julie Murphy and Jennifer Niven.Savannah is dreading being home alone with her overbearing mother after her big sister—and best friend—goes off to college. But if she can just get through senior year, she'll be able to escape to college, too. What she doesn't count on is that her mother's obsession with weight has only grown deeper since her appearance on an extreme weight-loss show, and now Savvy's mom is pressuring her even harder to be constantly mindful of what she eats. Between her mom's diet-helicoptering, missing her sister, and worrying about her collegiate future, Savvy has enough to worry about. And then she meets George, the cute new kid at school who has insecurities of his own. As Savvy and George grow closer, they help each other discover how to live in the moment and enjoy the here and now before it dis

Much has been written about Martin Luther King, Jr. and the 1963 March on Washington. But there's little on his legendary speech and how he came to write it. Find out more in this gripping book with i

A frog jumps. Boing! A kitten jumps. Boi-ing! A dog jumps. Boiyyyyyyoiingg! . . . "And I jump too—BOING!"This joyful book gets children joining in the fun of each animal's jump—sharing the sounds and

從嬌小的南美山貓到威風的老虎，貓科家族真是百變又迷人！你將透過漫畫的形式認識這些行動靈巧、牙爪俱全的獵人們如何征服森林、高山、沙漠，甚至人類的客廳！這本書不只揭開家貓的祖先與演化，也告訴你牠們如何從野性十足變成撒嬌賣萌的日常夥伴。科學、歷史、生態與可愛並存，喜歡貓、也喜歡探究「為什麼」的大小讀者絕不能錯過！Every volume of Science Comics offers a complete introduction to a particular topic—dinosaurs, the solar system, robots, and more. Whether you're a fourth grader doing a natural science unit at school or a thirty year old with a secret passion for airplanes, these books are for you!In Science Comics: Cats, we meet feline friends from the tiniest kodkod to the biggest tiger, and find out what makes your neighborhood domestic cats so special. Equipped with teeth, claws, and camouflage to survive everywhere from deserts to mountaintops, how did these ferocious felines make the leap from predators to playmates... and are they even done leaping?

The New York Times bestselling, official Minecraft novel: In the tradition of iconic adventures like Robinson Crusoe and Treasure Island, the author of World War Z tells the story of a hero—stranded i

A bright and friendly first colouring book for little ones, with simple objects to colour on every page. The backgrounds are already coloured in, so little children can focus on the exciting parts.

I love you more with each new day, with all my heart, in every way. Remind your little one just how much you love them with this adorable pop-up book.

Learn to count from ten to one and back again with this rhythmic, rhyming space adventure!Don't miss the latest book in the bestselling Ten Little series. Join the Ten Little Aliens as they jet off th

Welcome to the wonderful world of animal homes, incredible habitats where creatures rest high above our heads, and where burrowing beasts dig deep into the earth below our feet. Lift the flaps in this beautifully illustrated book to uncover some astonishing homes and the animals that live within.

Anna Llenas's popular Colour Monster is back, and this time he's heading off to school! But what exactly is school? A spooky castle filled with terrifying animals? A place in the sky, amongst the rain

《The Last Kids on Earth》首集描繪一個「殭屍與怪物佔領小鎮」的瘋狂世界。十三歲的 Jack Sullivan 原本平凡無奇，如今卻成了末日冒險者。他住進加固的樹屋，把生活過成一場遊戲般的挑戰：與好友 Quint 一起發明裝備、想辦法營救勇敢的 June、並嘗試擊敗最可怕的怪物 Blarg。作者 Max Brallier 的敘事幽默風趣，Douglas Holgate 的插圖動態十足，讓每一頁都充滿張力。故事節奏快速，笑料與動作兼備，尤其能吸引喜歡《Diary of a Wimpy Kid》或《Dog Man》的讀者。Terrifyingly fun! Max Brallier’s The Last Kids on Earth delivers big thrills and even bigger laughs.’ Jeff Kinney, author of Diary of a Wimpy Kid.SOON TO BE A MAJOR NETFLIX SERIES!‘Forty-two days ago I was an ordinary kid, living an uneventful life. But now it’s TOTAL MONSTER ZOMBIE CHAOS and I’m battling beasts on a daily basis. Crazy, right? But I know exactly how to make it through the zombie apocalypse.’Meet Jack Sullivan, self-described as a late-blooming, slow-developing 13-year-old who has so far survived the zombie apocalypse by hiding out in his treehouse. Overnight Jack’s life has become like the plot of a video game and he has come up with his own ULTIMATE FEATS OF APOCALYPTIC SUCCESS:· Locate Quint Baker, b

Jack Sullivan 的冒險繼續展開。末日小鎮依舊充斥著殭屍與怪物，但這次 Jack 已不再孤單，他和好友 Quint、Dirk 以及 June 共同作戰，還有忠誠的寵物怪獸 Rover 相伴。樹屋經過強化，配備各種防禦裝置，彷彿一座堡壘。然而，新的威脅逐步逼近，比過去任何敵人都更龐大、更危險。作者 Max Brallier 的文字節奏明快，加上 Douglas Holgate 的插圖幽默生動，使得緊張與笑料交織，閱讀體驗輕鬆愉快Soon to be a major NETFLIX series!‘Terrifyingly fun! Max Brallier’s The Last Kids on Earth delivers big thrills and even bigger laughs.’ Jeff Kinney, author of Diary of a Wimpy KidWimpy Kid meets The Walking Dead in this hilarious post-apocalyptic graphic novel series.Jack Sullivan is back.It’s still TOTAL MONSTER ZOMBIE CHAOS on the streets, but now Jack has a gang of friends to help him through – science genius and best friend Quint, super-strong Dirk and all-round coolest girl ever, June. Not to mention Rover, Jack’s awesome monster pet! Plus the treehouse is more souped up than ever, chockablock with defensive gizmos and ready to withstand anything that the monster apocalypse can throw at it.Which is just as well, because there’s something extra-big and extra-monstr

Jack Sullivan 與好友 June、Quint、Dirk 以為自己是世界上僅存的孩子，卻意外發現或許還有其他倖存者。這個消息令大家振奮，但 Jack 卻不安——他其實很享受與朋友們住在樹屋、對抗怪物的生活，不希望改變現狀。就在此時，一個比以往更強大的怪物「Nightmare King」出現，甚至能入侵 Jack 的思緒，使他陷入矛盾與恐懼。故事延續了快節奏與幽默風格，同時加入心理層面的描寫，讓角色更立體。Soon to be a major NETFLIX series!‘Terrifyingly fun! Max Brallier’s The Last Kids on Earth delivers big thrills and even bigger laughs.’ Jeff Kinney, author of Diary of a Wimpy KidWimpy Kid meets The Walking Dead in this hilarious series packed with monsters and zombies.In their third zombie-tastic adventure, Jack Sullivan and his friends June, Quint and Dirk discover that they might not be the last kids on Earth after all . . . And everyone is thrilled – except Jack. Living in a tree house with his best friends, battling monsters and escaping certain death – he's been having the most awesome time of his life. Somehow he's got to persuade his friends that life is perfect just the way it is . . . then they won't leave him.But that's not so easy when there's a new monster hunting th

故事場景進入冬季。Jack 與好友們在怪物末日後享受滑雪彈弓與雪球大戰，甚至籌辦屬於自己的聖誕慶典。然而歡樂不久，新的威脅登場──這次的敵人竟是人類反派。她奪走 Jack 最重要的武器 Louisville Slicer，而這把武器更牽連一個足以危及世界的黑暗陰謀。為了奪回武器並阻止災難，Jack 與伙伴們展開新一輪驚險旅程。故事融合動作、笑料與友情，插圖活潑生動，讓讀者在輕鬆氛圍中體驗冬季冒險的緊張刺激。Soon to be a major NETFLIX series!‘Terrifyingly fun! Max Brallier’s The Last Kids on Earth delivers big thrills and even bigger laughs.’ Jeff Kinney, author of Diary of a Wimpy Kid.The newest installment in this New York Times bestselling series introduces new monsters, new bad guys, and tons of new laughs – Diary of a Wimpy Kid meets The Waking Dead!It's the first winter after the Monster Apocalypse. For Jack and his buddies, that means sled catapults, epic snowball battles, and one monstrous Christmas celebration. But their winter wonderland turns dark when a villainess begins hunting them. And this villainess is different - she's a human.When the villainess steals Jack's prized monster-slaying tool, the Louisville Slicer, he vows to get it back. But it won't be easy. Jack and his f

What are phantom islands? How did the Black Death cause an ice age? How could graffiti save endangered tortoises? Find the answers to these questions and 97 more in this bold, graphic and exciting boo

What the Ladybird Heard 經典繪本套書內含：1. 9781509863167 The Singing Mermaid (1平裝+1CD) Tempted by the promise of fame and fortune, the Singing Mermaid joins a circus. The crowds love her, but the poor mermaid is kept in a tank by the wicked circus owner Sam Sly, and she soon longs to return to the freedom of her ocean home. The Singing Mermaid is a delightful tale from the stellar picture book partnership of Julia Donaldson and Lydia Monks, creators of What the Ladybird Heard.With brilliant rhyming verse, bright and distinctive illustrations and glitter on every page, this story is loved by children and parents alike. This paperback and CD edition features a fantastic reading of the story by Lauren Laverne. Enjoy all the stories from Julia Donaldson and Lydia Monks: Sharing a Shell, The Princess and the Wizard, The Rhyming Rabbit, The Singing Mermaid, Sugarlump and the Unicorn, Princess Mirror-Belle and the Dragon Pox, What the Ladybird Heard, What the Ladybird Heard Next and What the L