Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

“Mirage is a key work from the critical period of the early nineteenth century. It resembles a modern-day R-rated movie, touching on serious issues but containing scenes of explicit sexual pleasure and violent conflict.”—Keith McMahon First published anonymously in 1804—its author remains unknown—Mirage is set in Guangzhou (Canton), some decades before the city was overwhelmed by the opium trade and the Opium War. Su Jishi, the adolescent son of the head of the Chinese traders’ association, the men licensed to deal with foreign merchants in the port, is suddenly burdened with responsibility for his powerful family after his father’s unexpected death. More interested in sex than money, Su Jishi learns to navigate between pleasure and commerce, as rebellions erupt just outside the city. At the crossroads of two of the greatest Chinese books—the aristocratic coming-of-age novel, The Story of the Stone (The Dream of the Red Chamber) and the military epic Outlaws of the Marsh—Mirage i

This groundbreaking new book reveals never before known information about the time traveler from 2036 using the name John Titor.In 2000, a man calling himself John Titor began posting online claiming

In the tradition of Go Ask Alice and Lucy in the Sky, this heart-wrenching story chronicles a girl’s fatal experience with testing her moral limits and the dangers of addiction.Bailey welcomes a

Hurt people hurt people. Say there was a novel in which Holden Caulfield was an alcoholic and Lolita was a photographer’s assistant and, somehow, they met in Bright Lights, Big City. He’s blinded by l

Combining biting satire with a rare lightness of touch, cult webcomic Crocodile in Water Tiger on Land holds up a mirror to our times - and to all those who live in India, complicit in the muddle, whe

A dark and edgy first-person cautionary tale about how one girl’s seemingly minor choices quickly spiraled into a life as a sex worker in the tradition ofGo Ask Alice and Lucy in the Sky.She had a nor

His secret is his downfall. A riveting, first-person tale in the tradition of Go Ask Alice and Lucy in the Sky.The author of this fictional diary began writing for a class assignment, but soon it beca

A harrowing account of anorexia and addiction in the tradition of Go Ask Alice follows the experiences of a girl who in the face of low self-esteem and impossible expectations begins to feel a false s

A riveting first-person tale of addiction, in the tradition of Go Ask Alice and Jay’s Journal.The author of this diary began journaling on her sixteenth birthday. She lived in an upper middle class ne

Compiled by the Poor Clares of Rockford, Illinois. Beatified in 2007, this 19-year-old girl Germaine Castang suffered much in a desperately poor family, with illness, deaths and other sorrows---but he