Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

An action-packed activity book based on the newest LEGO(R) theme. Book comes with a buildable LEGO(R) minifigure.

Relive all of the humor and action of LEGO(R) Star Wars(TM) in this fun-filled activity book! Includes mazes, matching, code-breaking, puzzles, and more! Plus, buildable minifigure!

Following the hit format ofPapertoy Monsters, which has 159,000 copies in print, Papertoy Glowbots includes easy instructions, die-cut design templates, and imaginative back stories for 46 ingenious r

Sticker, Shape, Create is the first title in a stylish new art activity series for creative children, combining stickers and drawing. Using just a few basic sticker shapes and following simple step-by

In this captivating novel from the author of Wife 22, a woman who feels lost in her own time stumbles across a California community that has, impossibly, been marooned in the early twentieth century—p

Photography’s remarkable ability to represent the past in the present is frequently invoked as one of the medium’s essential characteristics. Yet, as many contemporary photographers acknowledge, its r

Detail in Contemporary Residential Architecture provides analysis of both the technical and the aesthetic importance of details in the development of contemporary residential architecture. Featuring m

Join Cole, Jay, Kai, Zane and Nya in their latest adventure across the exciting land of Ninjago. New enemies are rising! Do the team have what it takes to defeat them? LEGO(R) NINJAGO(TM): Team Ninja

TOUCHDOWN! James Patterson will have kids busting out laughingas they follow lovable bad-boy Rafe's struggles to score big on thefield--and in the social scene!In this seventh Middle School episode, R

Color plays a vital role in visual experiences. Professionals in design, fashion, architecture, and art are constantly exploring to find good solutions regarding color. In a globalizing world, color r

Mr Elf does not like holidays. But King Thistle thinks he deserves a break, so sends him for a well-earned rest in the sunshine with Mrs Elf, plus best friends Ben and Holly! Can Mr Elf learn how to r

Filled with pulse-pounding action and cryptic codes, The Golden Vendetta is the third engrossing book in bestselling author Tony Abbott's cloak-and-dagger series for young readers. Fans of R

Lucky Santangelo rules her family with an iron fist. But will she come out on top this time?"Get ready for a wild ride." --PopSugarA vicious hit. A vengeful enemy. A drug-addled Colombian cl

St Augustine's 'Confessions' was written between AD 397-400. An autobiographical work, it was written in thirteen parts, each a complete text intended to be read aloud. Written in his early 40s, it do

A theoretical physicist and jazz musician combines his two interests to present a new theory of the universe, using jazz to clarify confounding issues in physics and answer questions about the past an

In a YA trilogy like no other, Trent Reedy has raised the most primal questions of our national existence: Do we owe our greatest loyalty to our friends? Our state? Our country? Our party? How do we r

A reader featuring the newest LEGO(R) toy theme!

Even during the artist’s lifetime, contemporary art lovers considered Rembrandt van Rijn to be an exceptional artist. In this revelatory sequel to the acclaimed Rembrandt: The Painter at Work, renowned Rembrandt authority Ernst van de Wetering investigates precisely why the artist, from a very early age, was praised by prominent connoisseurs. He argues that Rembrandt, from his very first endeavors in painting, embarked on a journey past all the foundations of the art of painting that, according to (up until now misinterpretated) contemporary written sources, were considered essential in the seventeenth century. Rembrandt never stopped searching for solutions to the pictorial problems that confronted him; this led over time to radical changes in course that can’t simply be attributed to stylistic evolution or natural development. In a quest as rigorous and novel as the artist’s, Van de Wetering reveals how Rembrandt became the best painter the world had ever seen. Gorgeously illustrated

Adel Abdessemed (born 1971) has been a major figure in contemporary art since he entered the international creative world in the early 2000s. In 2012, after recent exhibitions in Nagoya, Venice, Londo

In recent years the sneaker scene has exploded with artist and designer collaborations. These specialist shoes are produced as short runs, using innovative or luxury materials, and often have bespoke

Laurie R. King’s Sherlock Holmes and Mary Russell novels—the New York Timesbestselling series that Lee Child calls “the most sustained feat of imagination in mystery fiction today”—will never be the s

In the early years of their love affair, Romilly was happy. She had worked hard for her stunning, modern house in one of Bristol's most fashionable suburbs. She adored her gorgeous, gap-toothed daught

In a publishing career that spanned less than a decade, Jane Austen revolutionized the literary romance, using it as a stage from which to address issues of gender politics and class-consciousness rar

Desire is more than skin deep When an international modeling opportunity called, Janna Morgan answered. The past nine years have brought her fame, fortune and supermodel status, but they haven't

Book #2 in The Case Files of Justis Fearsson, a new contemporary fantasy series from fantasy all-star David B. Coe. A hardboiled, magic-using private detective battles dark sorcerers in Phoenix, Arizo

Thirty-five years into the future, Batman's gotten himself caught in a P.O.W. camp where the enemy refuses to give up trying to crack the only "data source" he can't access—the human

You’re a farmer’s son living in England in the early 7th century. Your people are descendants of invaders from Northern Europe: the Angles, the Saxons and the Jutes, who arrived about 200 years earlie

The all-in-one guide to using English, including all the words, phrases and definitions you need and a unique full grammar of English to answer all those tricky questions. Language notes help you choo

Industrial manufacturing facilities have always been an own category in architecture. Ever since the development of factories in the 17th century this type of buildings have first of all served to imp

A true compendium of numerical brainteasers that is sure to test even the most ardent puzzle aficionado. So get ready to grab those pencils and prepare to indulge in this sanity testing compilation. R

This illustrated and highly readable book distills the key concepts of sustainable development, defines the issues at stake – by profiling the key environmental, economic, social and cultural challeng

Spanning forty years and bringing together works by artists such as Ai Weiwei, Cao Fei, and Fang Lijun, this volume follows the development of contemporary art in China in the new millennium. Focusing

Bestselling crime writers Peter Edwards and Antonio Nicaso reveal the final years of Canada's top mafia boss, Vito Rizzuto, and his bloody war to avenge his family and control the North American drug

A collection of delicious, no-fuss recipes that can be whipped up in minutes using shortcut ingredients.Perfect for today's busy home cooks, Cooking Light Dinner A.S.A.P. proves that a healthy meal ca

The time has come for the Battle Bugs to drive General Komodo's reptilian forces off Bug Island for good. Using all the knowledge Max has gained in his time with the Battle Bugs, he must lead the bug

The Chinese invented gunpowder and began exploring its military uses as early as the 900s, four centuries before the technology passed to the West. But by the early 1800s, China had fallen so far behind the West in gunpowder warfare that it was easily defeated by Britain in the Opium War of 1839-42. What happened? In The Gunpowder Age, Tonio Andrade offers a compelling new answer, opening a fresh perspective on a key question of world history: why did the countries of western Europe surge to global importance starting in the 1500s while China slipped behind?Historians have long argued that gunpowder weapons helped Europeans establish global hegemony. Yet the inhabitants of what is today China not only invented guns and bombs but also, Andrade shows, continued to innovate in gunpowder technology through the early 1700s--much longer than previously thought. Why, then, did China become so vulnerable? Andrade argues that one significant reason is that it was out of practice fighting wars,

New York Times bestselling author Simon R. Green returns to the Nightside with this landmark collection of short fiction.Welcome to the Nightside. It’s the secret heart of London, beating to its own r

隨著LTE及光纖興起，網路流量與用戶使用資訊越來越多，搭配雲端運算能力的提升，近幾年已經可以對這些大數據進行直接使用與分析，也產生與以往利用傳統統計模型所衍伸出之商業模式截然不同的作法，例如2014年11月IBM在台灣推出Big Data應用的雲端分析系統，輸入大量原始市場數據，並利用IBM雲端運算即時顯示企業客戶最佳的策略建議。其中電信業者在Big Data有所進展，全球電信運營商中，已有48％

In this new LEGO(R) CITY 8x8, a team of deep sea divers are on the search for sunken treasure. But could the old ship they find underwater be haunted? Find out in this funny, action-packed adventure f

Based on a proven six-step model and including examples and questions to guide application of those timeless principles,Curriculum Development for Medical Education is a practical guidebook for all fa