Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

STAEDTLER─Made in Germany 施德樓─對品質的堅持座落於Nuremberg 的企業總部，我們很驕傲的說，我們仍堅持在德國製造，那種對品質堅守承諾的傳統。相較於全世界各大品牌，紛紛以成本考量，寧願犧牲品質的現實考量，作為德國紐倫堡施德樓基金會的公司─"Made in Germany"是一種象徵著品質的使命與榮耀，我們有75％的產品，仍堅持著由這裡生產來發送全世界。品名：施德樓

STAEDTLER─Made in Germany 施德樓─對品質的堅持座落於Nuremberg 的企業總部，我們很驕傲的說，我們仍堅持在德國製造，那種對品質堅守承諾的傳統。相較於全世界各大品牌，紛紛以成本考量，寧願犧牲品質的現實考量，作為德國紐倫堡施德樓基金會的公司─"Made in Germany"是一種象徵著品質的使命與榮耀，我們有75％的產品，仍堅持著由這裡生產來發送全世界。品名：施德樓

STAEDTLER─Made in Germany 施德樓─對品質的堅持座落於Nuremberg 的企業總部，我們很驕傲的說，我們仍堅持在德國製造，那種對品質堅守承諾的傳統。相較於全世界各大品牌，紛紛以成本考量，寧願犧牲品質的現實考量，作為德國紐倫堡施德樓基金會的公司─"Made in Germany"是一種象徵著品質的使命與榮耀，我們有75％的產品，仍堅持著由這裡生產來發送全世界。品名：施德樓 Triplus ball F三角舒寫原子筆材質：塑膠商品規格：H16xW1.3xD1.3cm(測量有±2mm誤差值)數量：1入款式：黑產地：德國保存期限：妥善保存無期限適用年齡：九歲以上特色：˙符合人體工程學的三角形筆桿，書寫時既輕鬆又不易疲倦˙PP筆桿，筆蓋、筆頭和筆芯顏色一樣˙機艙適用-自動壓力平衡，不會因飛機上氣壓轉變引致漏墨˙F尖-線條寬度約0.5mm用途：一般書寫用使用方法：拆封即可使用注意事項：●請勿放置於潮濕處或高溫日照下●請勿放置於幼兒易取處●請勿接近火源以及腐蝕性溶劑●內有細小配件，請勿放入口中，以免誤食●九歲以下兒童請在成人監護下使用●六歲以下兒童不宜●須由成人拆開包裝，避免幼兒纏繞產生窒息●使用剪刀等相關工具時，應有家長陪同以免小朋友受傷●塑膠袋拆卸後，應立即丟棄。商品除瑕疵品外，恕不接受退換貨因拍攝略有色差，圖片僅供參考，顏色請以實際收到商品為準

收錄宮崎駿《風之谷》動畫電影幕後創作全記錄，從手繪草圖、水彩原稿到動畫分鏡與設定稿，完整呈現這部1984年經典之作的誕生歷程。見證一位動畫大師如何用畫筆建構出壯闊奇幻又深具環境意識的末日世界。An epic fantasy written and illustrated by the legendary director Hayao Miyazaki!An addition to the perennially popular line of Studio Ghibli art books—which include interviews, concept sketches, and finished animation cels—of classic animated films such as Spirited Away and My Neighbor Totoro.Hayao Miyazaki’sNausicaä of the Valley of the Wind, based on his own manga, was released in 1984 and has been a cult classic ever since. In a long-ago war, humankind set off a devastating ecological disaster. The earth is slowly submerging beneath the expanding Sea of Decay, an enormous toxic forest that creates mutant insects and poisonous spores. Beyond the sea lies the Valley of the Wind, a kingdom of barely 500 citizens and home to Nausicaä, who risks everything to save her people and bring peace and health to the valley. Includes sketches, developmental water colors, cel animation, and more.

In their fourth collection of poetry, Lambda Literary Award-winning poet and writer Leah Lakshmi Piepzna-Samarasinha continues her excavation of working-class queer brown femme survivorhood and desire

We’re keeping tabs on Maisy! Explore the many things in her world — indoors and out — with two tabbed board books that babies and toddlers will love.What kinds of things does Maisy see when she goes o

The newest title in the Welcome to the Museum series turns its focus to the heavens and explores the wonders of space.Welcome to the museum that is always open to explore. Step inside the pages of thi

Join favorite Disney Princesses Cinderella, Ariel, Belle, Rapunzel, Snow White, and Jasmine, featuring six bedtime stories in one very special storybook. Graced with gorgeous classic illustrations on

The Hearth Witch's Kitchen Herbal is an herbal with a difference—it shows how to use the herbs and spices most of us already have in our kitchens for home remedies, personal care, spiritual practice,

This playful book takes little children on a hide-and-seek adventure in search of the elusive little tiger. Die-cut holes on each page seem to reveal the tiger, only for it to turn out to be a differe

In August 1994, Manic Street Preachers released The Holy Bible, a dark, fiercely intelligent album that explored such themes as mental illness, murder and war. Richey Edwards, the band's lyricist and

Ram the farmer is in trouble. Bali the tiger has threatened to eat him, his wife and their children, unless Ram gives up his pretty white cow. But Reeta, Ram's clever wife, has a plan to outwit the hu

An imaginative story, ideal for children practising their reading at home or in school.When Jack kicks his ball over the garden wall, he meets Abbie, his mysterious neighbour, who gives him a glimpse

Andie dreams of becoming an artist. Her best paintings are inspired by the moon, and she’s excited to watch the first moon landing. She loves staying in Chelsea, with its fashion, music and art galler

The brilliant and hilarious debut from a rising star of the picture book world. Isobel's grandma has lost her glasses and she can't see a thing without them. While Isobel and Gran are in the garden se

Ruby Palace is no place for pets! But Princess Bea won't let royal rules stop her from helping animals in need... When Bea rescues a lost kitten, she promises to keep it safe until she can find its ow

Peep through the beautifully laser-cut pages to see Jack in his cottage, climb the beanstalk, enter the giant's house, and escape with the golden-egg-laying hen! This classic tale is charmingly, chara

Meekoo may be a big bear now, but even big bears have accidents sometimes. Everyone will enjoy the soundtrack to Meekoo's potty-training day - and they'll love joining in with the big cheer at the end!

When Crab finds a new shell, he doesn’t want to share it with anyone – especially not a blobby purple anemone and a tickly bristleworm. But life in the rock pool proves tougher than Crab thinks and he

NATIONAL BEST SELLERFrom the internationally acclaimed, best-selling author of The English Patient: a mesmerizing new novel that tells a dramatic story set in the decade after World War II through the

Celebrate like they do in The Big Easy with Chef Kevin Belton’s newest cookbook.The spotlight in this third book from the star of New Orleans Cooking with Kevin Belton is on the festivals and celebrations of the Big Easy and surrounding areas. New Orleans is known as the Festival Capital of the World, hosting dozens of annual festivals that showcase the unique food and multicultural heritage of the city.Kevin Belton’s New Orleans Celebrations will be a smorgasbord of delicious creations from vibrant festivals like the French Market Creole Tomato Festival, Bastille Day Fête, the Crescent City Blues and BBQ Festival, and more. Recipes include Ham Croquettes with Pear Pepper Jelly, Bacon and Barbecue Quiche, Crawfish Enchiladas and Creole Tomato, and Crawfish Macaroni and Cheese.

From demolishing a building to constructing a skyscraper, this fun activity book—with more than 250 stickers—shows children how things get built! Excavate. Lay the foundation. Create beautiful bridges and structures. This colorful sticker book takes children right onto a construction site to follow the entire building process from start to finish. They’ll even learn what dangers lurk in the scaffolding, machines, planks, and concrete! As they go along, kids can use the stickers to decorate the scenes in any way they like. Each spread features things to look for, find, and count, as well as fun facts and questions. A treasure hunt activity at the end encourages youngsters to go back and spot things they may not have noticed before.

Pudding Tat is born on the Willoughby Farm in 1901 — just another one of Mother Tat’s kittens. But it turns out that Pudding is anything but ordinary. He is pure white with pink eyes that, though beautiful, do not see well, and hearing that is unusually acute. He finds himself drawn to the sweet sounds of the world around him — the pattering heartbeat of a nearby mouse, the musical tinkling of a distant stream.Soon the sounds of adventure call to Pudding, too. But before he can strike out into the wide world on his own, he hears a voice — coming from right inside his own ear. A flea has claimed Pudding as his host. The bossy parasite demands that Pudding take him away from the lowly barn and the drunken singing of his fellow fleas. He doesn’t want adventure but a finer life — one where he can enjoy a warm bed and blood flavored not with mice, but with beef tenderloin and cream.Fortunately for this mismatched pair, the world is an extremely interesting place in 1901. Over the next decad

In this heartwarming follow-up to Laurel Snyder's awardwinning beginning chapter book Charlie & Mouse, the two brothers prepare to celebrate one very special birthday: their mom's! Follow along as the

Brush up your knowledge on popular American painter and illustrator Norman Rockwell with this exciting Who Was? title.Norman Rockwell often painted what he saw around him in nostalgic and humorous way

From popular author Ame Dyckman and rising star Charles Santoso comes the laugh-out-loud story of a father desperate to destroy the dandelion marring his perfectly manicured lawn, and his daughter's fierce attempts to save it. When Daddy spots a solitary weed in his lawn, he's appalled (along with all of his neighborhood friends). But his daughter Sweetie has fallen in love with the beautiful flower, even going so far as to name it Charlotte. Racing against time and the mockery of his friends, Daddy has to find a way to get rid of the errant dandelion without breaking his little girl's heart.

A beautifully-illustrated story about a girl who longs for magic in her life and learns that, on the inside, she already is what she wishes she could be. Reminiscent of Studio Ghibli, this lushly-draw

“An intense snapshot of the chain reaction caused by pulling a trigger.” —Booklist (starred review)“Astonishing.” —Kirkus Reviews (starred review)“A tour de force.” —Publishers Weekly (starred review)A Newbery Honor BookA Coretta Scott King Honor BookA Printz Honor BookA Los Angeles Times Book Prize Winner for Young Adult LiteratureLonglisted for the National Book Award for Young People’s LiteratureWinner of the Walter Dean Myers AwardAn Edgar Award Winner for Best Young Adult FictionParents’ Choice Gold Award WinnerAn Entertainment Weekly Best YA Book of 2017A Vulture Best YA Book of 2017A Buzzfeed Best YA Book of 2017An ode to Put the Damn Guns Down, this is New York Times bestselling author Jason Reynolds’s electrifying novel that takes place in sixty potent seconds—the time it takes a kid to decide whether or not he’s going to murder the guy who killed his brother.A cannon. A strap.A piece. A biscuit.A burner. A heater.A chopper. A gat.A hammerA toolfor RULEOr, you can call it a gu

This out-of-this-world kit for sci-fi lovers is loaded with special effects! It includes:-3-inch diameter spaceship, equipped with a hinged cockpit dome from which a curious alien peers, and featuring multiple light and sound effects:By opening the cockpit dome and pressing the alien's head, sound of spaceship engine plays, followed by eerie pre-abduction music. Six blue lights around the spaceship flash in rotation. Additionally, two bright LED lights beneath the ship glow, casting a beam of light in search of a specimen to abduct. When the spaceship is hovered in close proximity to the cow, a magnetically powered "abduction" occurs which simultaneously prompts new light and sound effects. Lights beneath the ship flash and music changes to a pulsating sound with intermittent cow mooing. When cow is abducted and alien head is pressed again, sound of the spaceship flying away plays, concluding your invasion and shutting off the spaceship.-Miniature cow and faux grass mound-Transparent d

Introducing a delightful collection of nursery rhymes, ideal for reading with young children. With 24 nursery rhymes in the book, children will have fun revisiting old favourites and learning new ones

Observing that the division between theory and empiricism remains inextricably linked to imperial modernity, manifest at the most basic level in the binary between “the West” and “Asia,” the authors o

Now in its seventh edition—with more than one million copies sold worldwide—The Relaxation and Stress Reduction Workbook remains the go-to resource for stress reduction strategies that can be incorpor

STAEDTLER─Made in Germany 施德樓─對品質的堅持座落於Nuremberg 的企業總部，我們很驕傲的說，我們仍堅持在德國製造，那種對品質堅守承諾的傳統。相較於全世界各大品牌，紛紛以成本考量，寧願犧牲品質的現實考量，作為德國紐倫堡施德樓基金會的公司─"Made in Germany"是一種象徵著品質的使命與榮耀，我們有75％的產品，仍堅持著由這裡生產來發送全世界。品名：施德樓

The Assassin tells the story of a swordswoman who refrains from killing. Hou Hsiao-hsien astonishes his audience once again by upsetting almost every convention of the wuxia (martial arts) genre in th

The students are sick and tired of Spaghetti-and-Meatball Mondays in the cafeteria. The administration says they can help create a new menu, so students throughout the school make booths with their fa

There was an old lady who swallowed a cake. I don't know why she swallowed the cake. It was a mistake!Scholastic's Old Lady is more popular than ever, and in celebration she's swallowing a cake... and

When Cyril, Anthea, Robert and Jane accidentally destroy a carpet in their London home with fireworks, their parents replace it with a second-hand one. Upon unfurling it, the children find an egg insi

Be brave and keep the seas safe!Nixie can't wait to join the Royal Mermaid Rescue Crew. Along with a magical seapony partner, she'll save merpeople in danger and use her natural creativity to keep the

"If you want us to remain silent - if you want to retain your freedom, your job, and your reputation - you need to tell us everything, and I mean everything. . ."We last saw Eve and Villanelle in a sp

An adorable board book for the babies and toddlers of gay fathers, featuring a variety of diverse, loving families with two dads.Families with same-sex parents are celebrated in this board book that f