Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

2019 marks the 50th birthday of Eric Carle's beloved classic story The Very Hungry Caterpillar. In this brand new board book, The Very Hungry Caterpillar is going to a birthday party and excitement is

From the classic tale by the Brothers Grimm. “Rapunzel, Rapunzel, let down your long hair!” A witch keeps Rapunzel in a tall tower without a door or stairs – but she isn’t the only one visiting the lo

From the well-loved French fairy tale, as retold by the Brothers Grimm. "Grandmother, what big eyes you have!" Little Red Riding Hood meets a wolf in the forest. He seems friendly, and he's interested

A brilliantly witty introduction to comparisons and opposites, illustrated by the winner of the Sainsbury’s Children’s Book Award.These children and animals are all very different to each other. Some are big, some are small. Some are gentle, some are rough. Everyone is playful, but who’s the best at hiding? One thing’s certain: they all love a good bedtime story!Shortlisted for the Sainsbury’s Children’s Picture Book Award, this is the perfect book for little ones who are just beginning to make sense of their place in the world. Karl Newson has created a simple, funny and heart-warming text, which is perfectly matched by Kate Hindley’s charming, brilliantly witty artwork, filled with detail.Every Nosy Crow paperback picture book comes with a free “Stories Aloud” audio recording. Just scan the QR code and listen along!

I've known you since you started.I've seen a thing or two . . .. . . or three or four or five or six!In fact, I've seen a few . . . Sometimes we are loud, sometimes we are quiet, sometimes bold and cl

This beautifully illustrated mini field guide is packed with information on more than 190 species of animal and plant that inhabit still-water bodies such as ponds, pools and small lakes in northern E

In 1834, Anne Lister made history by celebrating and recording the first ever known marriage to another woman. Now the basis for the HBO series Gentleman Jack, this is her remarkable, true story. Anne

履歷寫得好，但英文面試聽不懂？就靠《零基礎也不怕：七天搞定英文聽力！》關鍵單句╳生活對話╳單字發音全收錄搭配精闢聽力試題解析，幫助你從零基礎扎根！面試聽得懂，但表達能力不及格？交給《英文面試即戰力》精選例句╳回答範例╳資深面試官評論完整掌握這次讓你不只聽得懂，還回答得讓面試官都心服口服！有了絕對被錄取的面試「聽&說」戰略2 in 1，想進外商工作，能有多難？

The Art and Making of Aladdin offers the ultimate behind-the-scenes look into the 2019 live-action adaptation of the Disney classic, Aladdin.The streets of Agrabah come to vibrant life in Disney's 'Al

A.J. is gearing up for the summer of a lifetime in this holiday special from bestselling author Dan Gutman, whose My Weird School series has sold more than 23 million copies. Featuring 32 bonus pages

The most famouse goldsmith in Hawaii created a necklace for a famous actress, but someone wants to steal it! Can Geronimo figure out who the thief is before they run away with the jewels?

The fourth installment in the Avengers saga will be the culmination of 22 interconnected films and will let audiences witness the turning point of this epic journey. This collectible volume features a

Take another look at your favorite myths and legends in this hillarious new graphic novel by Mike Cavallaro!Got a problem? At Vulcan’s Celestial Supply Shop, you can find the magical merchandise to s

Raina Telgemeier and Frazzled fans, rejoice! Author-illustrator Kayla Miller is back with Olive in this emotional and honest story about navigating new experiences, learning to step outside one’s

NEWBERY HONOR BOOK • A poignant, personal, and hopeful tale of India's partition—and of one girl's journey to find a new home in a divided country.“[The Night Diary is] a sensitive portrayal of the universal search for identity and the need for a place to call home. Beautifully written, it weaves terror, family and faith into a timeless account of courage and strength.”—Laurie Halse Anderson, The New York Times"A gripping, nuanced story of the human cost of conflict appropriate for both children and adults."—Kirkus Reviews (One of the Best Middle Grade Books of the Century)It's 1947, and India, newly independent of British rule, has been separated into two countries: Pakistan and India. The divide has created much tension between Hindus and Muslims, and hundreds of thousands are killed crossing borders.Half-Muslim, half-Hindu twelve-year-old Nisha doesn't know where she belongs, or what her country is anymore. When Papa decides it's too dangerous to stay in what is now Pakistan, Nisha

本書是《Planet Omar》系列的第一集，主角Omar以第一人稱幽默敘述自己的新生活：搬新家、轉新校，還遇上班上愛找碴的惡霸。他一邊想交朋友、一邊努力不惹爸媽生氣，還要準備迎接開齋節的美食與禮物。Omar的世界充滿無限想像，從殭屍到龍，全都活靈活現地穿梭在日常煩惱之間。文字節奏輕快，插圖風格漫畫感十足，是一部能讓孩子從笑聲中找到共鳴的作品。推薦給喜歡 Tom Gates 或 Diary of a Wimpy Kid 的讀者。Welcome, readers, to the imaginative brain of Omar! You might not know me yet, but once you open the pages of this book you'll laugh so hard that snot will come out of your nose (plus you might meet a dragon and a zombie - what more could you want?).My parents decided it would be a good idea to move house AND move me to a new school at the same time. As if I didn't have a hard enough time staying out of trouble at home, now I've also got to try and make new friends. What's worse, the class bully seems to think I'm the perfect target.At least Eid's around the corner which means a feast (YAY) and presents (DOUBLE YAY). Well, as long as I can stay in Mum and Dad's good books long enough...The combination of Zanib Mian's hilarious text and Nasaya Mafaridik's fantastic cartoon-s

Have you ever wanted to find fairies in the garden, meet a unicorn, ride a dragon or share a picnic with a mermaid? Just because you’ve never seen these magical creatures doesn’t mean they don’t exist!The Wild Things of stories and the imagination are everywhere, but they’re shy, secretive, sometimes camouflaged and only reveal themselves to true believers.This fantastical guidebook will help you track dragons, create fashions fit for a fairy, brew magic potions, build snow unicorns, discover trolls and go on night hunts to capture Moon magic. Search forests, meadows, fields, ponds, rivers and the seaside, as well as everyday places like school playgrounds, local parks or among the pots on the patio.You can discover the mysteries of nature all year round and at any time of day or night. So switch your imagination on, use your senses, brush up on your magic skills and take a giant leap into the world of the Wild Things.Activities include:Tracking dragonsCreating fairy fashionsBrewing ma

颱風、龍捲風、洪水、森林大火……這些天災怎麼來的？是天氣發脾氣，還是我們對自然的誤解太多？古怪的氣象主播 Stormin' Norman 將用漫畫告訴你天氣與氣候的差別、氣象衛星怎麼預測未來、地球自轉如何影響風向，甚至解釋「氣象」跟「流星」有沒有關係。節奏明快、圖像生動，是孩子深入自然科學的最佳入門書，也是大人忍不住翻頁的氣候知識寶庫！Furious floods, looming landslides, terrifying tornadoes, ferocious forest fires! Is Mother Nature trying to tell us something? As “snowpocalypse” descends once again, one temperamental weatherman is determined to set the record straight on the myths and misconceptions surrounding the elements. What is the difference between weather and climate? How do weather satellites predict the future? Can someone outrun a tornado? Does the rotation of the Earth affect wind currents? And does meteorology have anything to do with meteors? Stormin’ Norman Weatherby is gearing up to answer all your wildest questions! Get ready to explore the depths of the ocean, the farthest reaches of space, and everything in between! These gorgeously illustrated graphic novels offer wildly entertaining views of their subjects. Whether you're a fourt

When President Obama visited Cairo to address Muslims worldwide, he followed in the footsteps of countless politicians who have taken the existence of a unified global Muslim community for granted. Bu

英文會話速成66公式，10倍速流利快可說，分分秒秒，直覺英語，聽力好！會話好！ 超強英語學習書，迫不及待成為英語高手。本書不是一本普通的英語會話教本。而是一本很好的英語學習教材，讓您學習省下20年。Talk a lot in English.我們的任務是使每位學英語的人，都能「學最純正、最常用的英語！」所以，本書的對話，都是生活中自然純正的美式英語會話，跟著學習，自然可以隨時隨地流利說出，連老外都

STAEDTLER─Made in Germany 施德樓─對品質的堅持座落於Nuremberg 的企業總部，我們很驕傲的說，我們仍堅持在德國製造，那種對品質堅守承諾的傳統。相較於全世界各大品牌，紛紛以成本考量，寧願犧牲品質的現實考量，作為德國紐倫堡施德樓基金會的公司─"Made in Germany"是一種象徵著品質的使命與榮耀，我們有75％的產品，仍堅持著由這裡生產來發送全世界。品名：施德樓

STAEDTLER─Made in Germany 施德樓─對品質的堅持座落於Nuremberg 的企業總部，我們很驕傲的說，我們仍堅持在德國製造，那種對品質堅守承諾的傳統。相較於全世界各大品牌，紛紛以成本考量，寧願犧牲品質的現實考量，作為德國紐倫堡施德樓基金會的公司─"Made in Germany"是一種象徵著品質的使命與榮耀，我們有75％的產品，仍堅持著由這裡生產來發送全世界。品名：施德樓

STAEDTLER─Made in Germany 施德樓─對品質的堅持座落於Nuremberg 的企業總部，我們很驕傲的說，我們仍堅持在德國製造，那種對品質堅守承諾的傳統。相較於全世界各大品牌，紛紛以成本考量，寧願犧牲品質的現實考量，作為德國紐倫堡施德樓基金會的公司─"Made in Germany"是一種象徵著品質的使命與榮耀，我們有75％的產品，仍堅持著由這裡生產來發送全世界。品名：施德樓 Triplus ball F三角舒寫原子筆材質：塑膠商品規格：H16xW1.3xD1.3cm(測量有±2mm誤差值)數量：1入款式：黑產地：德國保存期限：妥善保存無期限適用年齡：九歲以上特色：˙符合人體工程學的三角形筆桿，書寫時既輕鬆又不易疲倦˙PP筆桿，筆蓋、筆頭和筆芯顏色一樣˙機艙適用-自動壓力平衡，不會因飛機上氣壓轉變引致漏墨˙F尖-線條寬度約0.5mm用途：一般書寫用使用方法：拆封即可使用注意事項：●請勿放置於潮濕處或高溫日照下●請勿放置於幼兒易取處●請勿接近火源以及腐蝕性溶劑●內有細小配件，請勿放入口中，以免誤食●九歲以下兒童請在成人監護下使用●六歲以下兒童不宜●須由成人拆開包裝，避免幼兒纏繞產生窒息●使用剪刀等相關工具時，應有家長陪同以免小朋友受傷●塑膠袋拆卸後，應立即丟棄。商品除瑕疵品外，恕不接受退換貨因拍攝略有色差，圖片僅供參考，顏色請以實際收到商品為準

收錄宮崎駿《風之谷》動畫電影幕後創作全記錄，從手繪草圖、水彩原稿到動畫分鏡與設定稿，完整呈現這部1984年經典之作的誕生歷程。見證一位動畫大師如何用畫筆建構出壯闊奇幻又深具環境意識的末日世界。An epic fantasy written and illustrated by the legendary director Hayao Miyazaki!An addition to the perennially popular line of Studio Ghibli art books—which include interviews, concept sketches, and finished animation cels—of classic animated films such as Spirited Away and My Neighbor Totoro.Hayao Miyazaki’sNausicaä of the Valley of the Wind, based on his own manga, was released in 1984 and has been a cult classic ever since. In a long-ago war, humankind set off a devastating ecological disaster. The earth is slowly submerging beneath the expanding Sea of Decay, an enormous toxic forest that creates mutant insects and poisonous spores. Beyond the sea lies the Valley of the Wind, a kingdom of barely 500 citizens and home to Nausicaä, who risks everything to save her people and bring peace and health to the valley. Includes sketches, developmental water colors, cel animation, and more.

In their fourth collection of poetry, Lambda Literary Award-winning poet and writer Leah Lakshmi Piepzna-Samarasinha continues her excavation of working-class queer brown femme survivorhood and desire

The newest title in the Welcome to the Museum series turns its focus to the heavens and explores the wonders of space.Welcome to the museum that is always open to explore. Step inside the pages of thi

Join favorite Disney Princesses Cinderella, Ariel, Belle, Rapunzel, Snow White, and Jasmine, featuring six bedtime stories in one very special storybook. Graced with gorgeous classic illustrations on

"A bold and subversive retelling of the goddess's story," this #1 New York Times bestseller "manages to be both epic and intimate in its scope, recasting the most infamous female figure from the Odyss

We’re keeping tabs on Maisy! Explore the many things in her world — indoors and out — with two tabbed board books that babies and toddlers will love.What kinds of things does Maisy see when she goes o

The Hearth Witch's Kitchen Herbal is an herbal with a difference—it shows how to use the herbs and spices most of us already have in our kitchens for home remedies, personal care, spiritual practice,

This playful book takes little children on a hide-and-seek adventure in search of the elusive little tiger. Die-cut holes on each page seem to reveal the tiger, only for it to turn out to be a differe

In August 1994, Manic Street Preachers released The Holy Bible, a dark, fiercely intelligent album that explored such themes as mental illness, murder and war. Richey Edwards, the band's lyricist and

Ram the farmer is in trouble. Bali the tiger has threatened to eat him, his wife and their children, unless Ram gives up his pretty white cow. But Reeta, Ram's clever wife, has a plan to outwit the hu

An imaginative story, ideal for children practising their reading at home or in school.When Jack kicks his ball over the garden wall, he meets Abbie, his mysterious neighbour, who gives him a glimpse

Andie dreams of becoming an artist. Her best paintings are inspired by the moon, and she’s excited to watch the first moon landing. She loves staying in Chelsea, with its fashion, music and art galler

The brilliant and hilarious debut from a rising star of the picture book world. Isobel's grandma has lost her glasses and she can't see a thing without them. While Isobel and Gran are in the garden se

Ruby Palace is no place for pets! But Princess Bea won't let royal rules stop her from helping animals in need... When Bea rescues a lost kitten, she promises to keep it safe until she can find its ow

When Crab finds a new shell, he doesn’t want to share it with anyone – especially not a blobby purple anemone and a tickly bristleworm. But life in the rock pool proves tougher than Crab thinks and he

Peep through the beautifully laser-cut pages to see Jack in his cottage, climb the beanstalk, enter the giant's house, and escape with the golden-egg-laying hen! This classic tale is charmingly, chara

Meekoo may be a big bear now, but even big bears have accidents sometimes. Everyone will enjoy the soundtrack to Meekoo's potty-training day - and they'll love joining in with the big cheer at the end!