Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Designed as a textbook for a one or two-term introduction to mathematical statistics for students training to become data scientists, Foundations of Statistics for Data Scientists: With R and Python is an in-depth presentation of the topics in statistical science with which any data scientist should be familiar, including probability distributions, descriptive and inferential statistical methods, and linear modelling. The book assumes knowledge of basic calculus, so the presentation can focus on 'why it works' as well as 'how to do it.' Compared to traditional "mathematical statistics" textbooks, however, the book has less emphasis on probability theory and more emphasis on using software to implement statistical methods and to conduct simulations to illustrate key concepts. All statistical analyses in the book use R software, with an appendix showing the same analyses with Python.The book also introduces modern topics that do not normally appear in mathematical statistics texts but ar

This reference book compiles the recent advances in computational and experimental modeling to screen and manage Alzheimer's disease. The book discusses how computer-aided drug design approaches reduc

The world is periodically consumed in violence, in recent years by the Russian invasion of Ukraine, Hamas’ October 7th terrorism in Israel, and by the genocide of Palestinians in Gaza by Israelis in response. To this world-historical situation, this book attempts a curriculum studies response.

This book provides information about deadly viruses causing the pandemics in the world and provides clarity about the epidemiology of the diseases. The authors also present information on drug discove

Instrumentation and Measurements in Compressible Flows presents detailed information on experiments in compressible fluid flows including technical information pertaining to a wide variety of applicat

This book provides a general framework for learning sparse graphical models with conditional independence tests. It includes complete treatments for Gaussian, Poisson, multinomial, and mixed data; uni

This book provides a significant contribution to the increasing conversation concerning the place of big data in education. Offering a multidisciplinary approach with a diversity of perspectives from international scholars and industry experts, chapter authors engage in both research- and industry-informed discussions and analyses on the place of big data in education, particularly as it pertains to large-scale and ongoing assessment practices moving into the digital space. This volume offers an innovative, practical, and international view of the future of current opportunities and challenges in education and the place of assessment in this context.

How did early modern societies think about disasters, such as earthquakes or floods? How did they represent disaster, and how did they intervene to mitigate its destructive effects? This collection sh

Drug counterfeiting detection is very important for the safety of patients globally. Counterfeit detection devices have been used for qualitative and quantitative assessment to differentiate counterfe

An introductory review of electric energy using examples, numerical calculations and theory to describe the basic elements of the field. Coverage includes electric infrastructure, the grid, system operations, renewable energy, alternating current circuits, three-phase power, power electronics, blackouts and future power systems.

From the pre-Islamic Jahilia, early modern Sikri and Florence, to postcolonial Bombay and Karachi, cities have played a pivotal role in Salman Rushdie’s fiction. This book focuses on spatial concerns

Expanding on the highly successful previous two editions, this third edition of Proton Therapy Physics has been updated throughout and includes several new chapters on “Adaptive Proton Therapy,” "Imaging for Planning,” “Flash Proton Therapy,” and “Outcome Modeling for Patient Selection.” Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, this book provides an in-depth overview of the physics of this radiation therapy modality, eliminating the need to dig through information scattered across medical physics literature. After tracing the history of proton therapy, this book explores the atomic and nuclear physics background necessary for understanding proton interactions with tissue. The text then covers dosimetry, including beam delivery, shielding aspects, computer simulations, detector systems, and measuring techniques for reference dosimetry.Important for daily operations, acceptance testing, commissioning, quality assurance, and monit