Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

This book teaches children about the basic principles of science through 30 exciting experiments and crafts that can be done at home, using everyday objects and materials around you. Why do bubbles ho

Big Data is made up of lots of little data: numbers entered into cell phones, addresses entered into GPS devices, visits to websites, online purchases, ATM transactions,

Marketing Science Using R 重點探討行銷科學領域 相關統計觀念及R語言 ※內容詳解行銷科學的應用‧ ※強化解決行銷領域的問題 ※配合豐富的行銷實例說明 ※輕鬆理解並有效解決問題 本書適用於對行銷科學方法感興趣的讀者，不管是有心進入行銷領域的資訊管理背景人士，或是尋找量化分析工具的行銷從業人員，提供了理論與實務的最佳參考書籍。 【本書特色】 *直指行銷科學領域的應用層面，以解

本書《R語言與資料分析實戰》以R語言的「程式設計屬性」為中心，內容涵蓋R語言基礎理論到實際資料分析，透過分析模型和演算法等更實用的範例，講解了資料視覺化、統計分析、資料採擷、機器學習等常用的方法。同時書中還收錄了作者的實戰經驗和學習體會，可以解決資料統計分析過程中出現的各種問題。如果你是一名資料統計分析的研究人員，本書將是一本不可多得的參考書，能夠深化理解與認識R軟體的應用，進一步提高資料統計分析

Soccer is the most mathematical of sports--riddled with numbers, patterns, and shapes. How to make sense of them? The answer lies in mathematical modeling, a science with applications in a host of bio

A NEW ORIGINAL SERIES, NOW ON HBO.Here is the first volume in George R. R. Martin’s magnificent cycle of novels that includes A Clash of Kings and A Storm of Swords. As a whole, this series comprises

GAME OF THRONES: A NEW ORIGINAL SERIES, NOW ON HBO.Here is the third volume in George R. R. Martin’s magnificent cycle of novels that includes A Game of Thrones and A Clash of Kings. As a whole, this

內 容 提 要R語言中的tidyverse包可以使數據的處理、轉換和可視化變得簡單、合理且可複製，大大簡化了數據整理的過程。本書詳細介紹了tidyverse包，主要內容包括R語言基礎知識，數據導入，數據整理，數據變換，處理日期、因子與字符串，數據可視化，編程，建模等內容。本書圖文結合，實例豐富，語言通俗易懂，既適合商業數據分析從業者閱讀，也適合科研工作者、統計工作者(特別是醫學統計從業者)及各大專院校相關專業的師生等學習。

Created by a teacher, Bob Books have been helping children learn to read for more than forty years! This set gives children who are just beginning to read practice with their early phonics skills, setting them up for success on their reading journeys!With playful stories, silly illustrations, and a phonics approach based on Science of Reading research, Bob Books keep young readers'' confidence high, leading to continued success and a love of reading. Your child will soon join the millions of happy kids who say, "I read the whole book!"®Science of Reading research proves that mastering phonics is key to a child''s success in learning to read. Like all Stage 1 Bob Books, these 12 storybooks feature simple words with consistent short vowel sounds. Early readers get lots of practice with foundational phonics skills while giggling at the playful stories and pictures!This set is perfect for children who have never read Bob Books, or for children who have read Bob Books Beginning Readers or B

如果你主要關注統計分析、數據可視化、線性代數、初等微積分，並希望較快上手，「R語言」會是較佳的選擇！本書獨特之處在於以直觀且實用的方式，清楚介紹人工智慧及機器學習領域中常用的管理數學工具。透過R語言的實作，讀者得以深入理解並實際應用於不同實務情境。書中的實例不侷限於理論探討，更著重實際應用，貼近日常生活，喚起讀者對數學的共鳴與學習熱情。舉例而言，透過應用貝氏定理，探討運動員實際服用興奮劑的真相，以及判斷過濾垃圾郵件的情境。同時，透過極佳化方法的應用，協助航空公司訂定最適價格和最大利潤路線圖等案例，使得理論更具實用性。除此之外，本書擴大管理數學的範疇：從管理數學傳統上僅處理統計、線性代數的刻板印象，將此核心概念延伸至線性轉換、特徵值與特徵向量等進階議題，並且更進一步涵蓋一般書籍較少觸及的「極佳化方法」，包括微分、極值、偏微分以及拉氏乘數等內容，於實用範例中為機器學習（Machine learning）的數學應用奠定基礎。線性規劃的討論更是引領讀者回溯至二戰時期，線性規劃應用於確定空中力量和雷達（radar）的最佳使用，具有時代非凡之意義。同時探討在各種混和限制條件下，欲達目標極大、極小化，使用線性代數中構築人工基底手法，自標準的極大化問題做為起點，經二階段法、對偶問題法、對偶單形法，深入解說 R 軟體 lpSolveAPI 套件背後的數學脈絡或故事。本書精彩內容 ——線性代數｜線性函數｜線性方程組｜矩陣｜向量空間｜線性轉換｜極佳化方法｜拉氏函數｜機率與統計｜單利．複利｜線性規劃｜馬可夫鏈｜預測｜本書特色☑ 以 R 軟體的程式語言與過程，深入解說並印證數學定義、定理☑ 透過 R 軟體的印證，經驗的移轉，形塑跨電腦語言的整體處理思維☑ 促成 R 軟體成為數學符號以外的第二語言，加速數學學習效率☑ 將人工智慧及機器學習常用之數學思維，應用於資料分析及解決管理問題

本書特色除了告訴讀者統計學是什麼以及有何應用, 本書也注重讓讀者認知到, 為什麼要學這些統計理論的理由與動機。對於統計理論的介紹, 講求其背後直覺以及應用。每一章節都專注在回答一個問題, 讓讀者能夠迅速掌握學習重點。著重模擬與數值計算, 減少繁雜的理論證明細節。對於證明的細節, 有興趣學習更多的讀者可進一步參考《機率與統計推論: R 語言的應用》 (第 2 版, 2023)。每一章均有 R 程式習題, 或是理論與程式的混合題, 讓讀者從 R 程式的撰寫中, 驗證相關理論, 俾使更為深入了解機率與統計學。 對於 bootstrap 樣本重抽法與貝氏統計推論提供更加細膩的討論。 本書從 R 語言的介紹開始, 最後以貝氏統計推論作為結束, 本書不討論迴歸分析。理由在於, 迴歸分析在經濟商管領域已經被進一步延伸為計量經濟學, 與其在本書中略述皮毛, 不如另起爐灶, 期待在下一本著作中再深入討論。

Even if trapped in darkness, one will always search for the light.This is a story of a young police officer searching for the answer to "Who am I?"In the past, Xie Lanshan was an undercover drug enforcement officer who infiltrated the Golden Triangle's most feared armed organization as drug lord Mu Kun's right-hand man. After successfully returning to his post from the operation, an accidental case of police misconduct triggers a series of unexplainable headaches and hidden memories that begin to haunt him.While investigating the truth behind his father's death of many years ago, Xie Lanshan utilizes his unique and sharp thinking from the perspective of a psychotic murderer to solve difficult cases around him. Plagued by this growing change and instability of both his mental health and personality, he meets a mysterious forensic sketch artist named Shen Liufei. Together, the two men will maintain a strange relationship; as friends and enemies, they solve mysterious cases one by one.But

From the multi-award winning author of The Bridge (BBC) and Marcella (Netflix, ITV) comes a blockbuster new thriller… A DEAD WOLFA DRUG DEAL GONE WRONGA LETHAL FEMALE ASSASSINHannah Wester, a detective in the remote northern Swedish town of Haparanda, finds herself on the precipice of chaos.When human remains are found in the stomach of a dead wolf, Hannah knows that this summer won’t be like any other. The remains are soon linked to a bloody drug deal that went down just across the border in Finland. But how did the victim end up in the woods outside Haparanda? And where have the drugs and money gone?Hannah and her colleagues are soon caught up in an increasingly complex investigation. But time is scarce and they aren’t the only ones looking.When the secretive and deadly Katja shows up, unexpected and brutal events start to pile up. In just a few days, life in the border town is turned upside down. Not least for Hannah, who is finally forced to confront her own past.

運用R和Python學習50+個必學統計概念 「這本書並非是另一本統計學教科書，也不是機器學習手冊。本書透過清楚的解釋和豐富範例，將實用的統計術語及原理和當今資料探勘的行話及實務聯繫起來。對資料科學的初學者和老手來說，這都是一本非常出色的參考書。」 ―Galit Shmueli, 暢銷書《Data Mining for Business Analytics》主要作者，台灣清華大學特聘教授 統計方法

※ R正逐步成為統計分析的主流。※ 每章開頭簡短扼要提醒該種統計方法適用的情境。※ 強調各種統計方法的基本假定，避免誤用工具。※ 內容涵蓋多數的單變量統計方法，以及常用的多變量分析技術。※ 本書可供基礎統計學及進階統計學教學之用。※ 配合研究生及學者進行量化研究分析與撰寫論文之需。精熟應用統計軟體，是研究人員與資料分析人員須具備的基本能力。目前有許多統計軟體可供選擇，然而，多數都需要付費購買，也無

本書共分十一章，涵蓋市面上一般統計學教科書編寫的範圍。編寫方式分為筆算和電腦分析，筆算是為了讓讀者了解計算過程，筆算後緊接著解法分析，目的是讓讀者了解為什麼要這樣計算。除了筆算外，本書亦側重電腦分析，列有Excel、SAS、R分析供讀者對照學習。面對大數據分析的迫切需求，本書每個章節針對統計理論搭配R程式供學生學習，這對於日後接續學習高階大數據分析有著極大的幫助。

Access in easy steps has an easy-to-follow style that will appeal to anyone who wants to get more from the Microsoft Access app. Whether you’re using Access in the Office 365 suite or standalone Offic

Working in partnership with the RSC, this brand new series is ideal for introducing students to Shakespeare's plays. Using trusted and established RSC approaches, Shakespeare's plays come to life in t

Do you know that water covers nearly 70 percent of the earth and that nearly 70 percent of the human body is made up of H2O? That more than half of the earth's species live in water? Or that the sea r

This nontechnical guide provides helpful advice and insight for those who are in an intimate relationship with someone diagnosed with Asperger syndrome. Although the American Psychiatric Association r

Brilliantly evoking the long-vanished world of masters and servants portrayed in Downton Abbey and Upstairs, Downstairs, Margaret Powell’s classic memoir of her time in service, Below Stairs, is the r

BESTSELLING AUTHORS GO HOLMES—IN AN IRRESISTIBLE NEW COLLECTION edited by award-winning Sherlockians Laurie R. King and Leslie S. Klinger?Neil Gaiman. Laura Lippman. Lee Child. These are just three of

The year is 2054, and life has been reduced to a data feed. The fusing of virtual reality and cybernetics has ushered in the era of the surrogate, a new technology that lets users interact with the wo

★ 荒謬任務 × 真實科學！用化學實驗破解超狂危機★ 海盜求生、恐龍蛋運送、秘密訊息傳遞——科學就是最強超能力！★ 步驟清楚的趣味實驗，讓孩子邊玩邊學、動手探索STEM世界★ 暢銷童書作家 Swapna Haddow × 科普漫畫插畫家 Jess Bradley 爆笑合作當荒謬任務遇上真正的科學，冒險就開始了！本書以爆笑情境帶出化學原理，搭配簡單易懂的實驗，讓孩子在動手操作中理解科學概念。從秘密訊息到瞬間冰淇淋，每一個實驗都像一場小小冒險。結合漫畫式插圖與幽默故事，是讓孩子愛上STEM的最佳入門讀物。A funny children’s illustrated science book with experiments for ages 8+ that is new for 2026Bonkers dilemmas that can be solved with science and a bunch of brilliant chemistry experiments.Survive at sea with pirates! Carry a dinosaur egg across the jungle! Send secret messages! Make diamonds from pencils!Explore a bunch of ridiculous (and not-so-ridiculous) dilemmas – with solutions from the astonishing world of chemistry.Sounds unbelievable? Test the science for yourself, with easy-to-follow experiments throughout!What are you waiting for? Let’s become millionaires!Written by bestselling and award-winning author Swapna Haddow, with brilliantly funny colour illustrations from award-winning illustrator Jess Bradley.BOOK 1 OUT NOW: How to

Dante’sInfernomeetsSusanna Clarke’sPiranesiin this all-new dark academia fantasyfrom R. F. Kuang, the #1New York Timesbestselling author ofBabel and Yellowface,in which two graduate students must put aside their rivalry and journey to Hell to save their professor’s soul—perhaps at the cost of their own.Katabasis, noun, Ancient Greek:The story of a hero’s descent to the underworldAlice Law has only ever had one goal: to become one of the brightest minds in the field of Magick. She has sacrificed everything to make that a reality: her pride, her health, her love life, and most definitely her sanity. All to work with Professor Jacob Grimes at Cambridge, the greatest magician in the world.That is, until he dies in a magical accident that could possibly be her fault.Grimes is now in Hell, and she’s going in after him. Because his recommendation could hold her very future in his now incorporeal hands and even death is not going to stop the pursuit of her dreams….Nor will the fact that her ri

★ 爆笑科學任務登場！用物理實驗拯救奶奶、破解超荒謬危機★ 圖像漫畫風＋實驗活動，一邊大笑一邊動手做科學★ 英國暢銷童書作家 Swapna Haddow × 科學漫畫家 Jess Bradley★ 15種超好玩的 STEM 實驗，從「蛋殼橋」到「電磁鐵」都能自己試一本把科學變成爆笑冒險任務的圖像科普書。孩子將在「拯救奶奶」、「阻止火車」、「騙過鯊魚」等瘋狂情境中，透過簡單有趣的實驗理解物理原理。結合漫畫式插圖與動手做活動，讓 STEM 不再枯燥，而是一場充滿驚喜與笑聲的科學冒險。A funny children’s illustrated science book with experiments for ages 8+ that is new for 2025Bonkers dilemmas that can be solved with science and a bunch of brilliant physics experiments.Book of the Week: The Week Junior***No grannies were harmed in the making of this book!**Trick a shark! Lift a jumbo jet! Escape a deserted island! Stop a runaway train!Explore a bunch of ridiculous (and not-so-ridiculous) dilemmas – with solutions from the astonishing world of physics.Sounds unbelievable? Test the science for yourself, with easy-to-follow experiments throughout!What are you waiting for? Let’s save Granny!Written by bestselling and award-winning author Swapna Haddow, with brilliantly funny colour illustrations from award-winning illustrator Jess Br

《Troubled》是一本動人且引人深思的回憶錄，講述Rob Henderson從破碎家庭、寄養制度到美國空軍，再到耶魯與劍橋求學的奮鬥歷程。他提出「奢侈信念」(luxury belief) 的觀念，揭示上層社會藉由炫耀進步思想來獲取地位，卻讓弱勢者承受代價。本書深刻描繪階級、家庭與身分的掙扎，令人動容。NATIONAL BESTSELLER In this "affecting...intriguing...heartbreaking" (Booklist) coming-of-age memoir, Rob Henderson vividly recounts growing up in foster care, enlisting in the US Air Force, attending elite universities, and pioneering the concept of "luxury beliefs"--ideas and opinions that confer status on the upper class while inflicting costs on the less fortunate. Rob Henderson was born to a drug-addicted mother and a father he never met, ultimately shuttling between ten different foster homes in California. When he was adopted into a loving family, he hoped that life would finally be stable and safe. But divorce, tragedy, poverty, and violence marked his adolescent and teen years, propelling Henderson to join the military upon completing high school. A "vivid, insightful, poignant, and powerful" (Nicholas A. Christakis, author of

Inside Scouts: An Acorn Book (Book1-3)The Inside Scouts Viv and Sanjay help a lion with a leaky heart in this full-color early reader series!Pick a book. Grow a Reader!This series is part of Scholastic's early reader line, Acorn, aimed at children who are learning to read. With easy-to-read text, a short-story format, plenty of humor, and full-color artwork on every page, these books will boost reading confidence and fluency. Acorn books plant a love of reading and help readers grow!Viv and Sanjay are the Inside Scouts! Together, they help animals. They have a cool superpower -- they can shrink super small. When a lion with a leaky heart needs help, the Inside Scouts know what to do! They put on their suits, grab their tools, and get really small. They go inside the lion to find the leaky spot. And they fix it together!This series introduces beginning readers to the human body through mammals with similar anatomy -- and it does so in really fun ways! In this first book, readers learn a

★建立線上音檔：掃描 QR code 上線，跟著音檔練習，加速上手效率。 本書統整了各式各樣的R&B吉他演奏技巧，除了能讓熱愛R&B的吉他手遊賞其中奧妙以外，也能活用在近年再次掀起熱潮的Neo City Pop、Neo Soul等音樂上。本書以大量篇幅來介紹R&B吉他代表性的過門演奏，徹底解說從和弦指型去構思樂句的手法。此外，內容也囊括能夠彰顯吉他魅力的和弦構策、R&B風刷弦技巧、Funk的切分手法等五花八門的演奏風格。

CEFR Correlation:A2Get Ready for International BusinessTo be ready to use English in the workplace, students need to• be exposed to a variety of business and workplace situations• build confidence in using English communicatively for workGet Ready for International Business helps students prepare to use English in the workplace by• exposing them to English being used in a range of different business contexts• giving students practice in reading an assortment of texts• offering a variety of different accents in the listening exercises and the cross-cultural Viewpoints sections that feature a wide range of people talking about aspects of business and culture• focusing on developing learners’ listening and speaking skills through carefully graded activities• explicitly teaching key conversation strategies to help them manage conversations in business settings• providing In business tasks that allow students to use the language studied in business simulations to develop their own professio

本書特色 這是一本因應電腦世代 (computer age) 所寫成的統計學教科書。書中增加了有關 R 語言的介紹,並盡可能在各個章節中,說明電腦以及 R 語言如何在機率與統計推論上,發揮其功用。其中,我們在第 19 章介紹蒙地卡羅模擬與 Bootstrap 樣本重抽法,希望讀者對於如何以電腦運算能力輔助統計推論能有一較為深入的認識。本書的章節安排,是根據我在台大經濟系講授 「統計學」 課程的多年教學經驗所整理出之架構。在介紹完機率模型後,緊接著介紹單變量與多變量隨機變數。關於動差的討論,則是從隨機變數的章節抽離出來,獨立成為第 5 章。同時,亦將常態分配以及與其相關的重要分配如卡方分配,學生 t 分配與 F 分配等,以一獨立章節 (第 6 章) 介紹。這本書的設計目標是,讓學生在得到足以駕馭統計推論的機率理論 (隨機變數,動差,常態分配,抽樣分配與大樣本理論) 之後,就開始一窺統計推論之堂奧。至於其他常用的離散與連續隨機變數,則移到統計推論相關章節的後面,因此,如果是一學期的統計課程,只要專注在第 1 到 11 章即可,關於其他常用離散與連續隨機變數之介紹,可於學期末得空時再補充。我在本書中不再討論變異數分析 (ANOVA),有興趣的讀者請自行參考陳旭昇 (2015)。

本書為進階的教材，需要經濟計量方法和矩陣代數的基礎。時間序列預測是統計學裡非常實用的工具，不論是分析投資組合的數據、全球總經和金融市場，以及預測景氣循環變動等等，可以用過去的數據資料，預測未來趨勢，是可以符合實際決策需要的實用能力。書中並介紹機器學習方法，機器學習不是指特定估計方法，學習指的是如何在資料結構中運算，以追蹤最小預測誤差的方法獲得最佳預測(tuning)。我們應用機器學習演算法訓練歷史資料，執行特徵萃取(features extraction)，再測試預測表現。依此建立一個可預測未來的模型，作為決策之用。使用R語言進行時間序列預測是本書的一大特點，R語言是統計學中普及且容易上手的分析工具，書中針對一個個資料分析步驟進行深度解說，教給讀者進行預測與評估的最實用方法。

It’s eat or be eaten...literally!Locked in battle with the Lunatic Magician, Laios is the last man standing against an array of the dungeon’s deadliest dragons. Using his extensive monster knowledge to his advantage, Laios manages to defy the odds of almost certain death―at least until Sissel devises an even more terrible plan! Will Laios’s love of dungeon dining prove to be his downfall?

A Magic Spark: An Acorn Book (Fairylight Friends #1)Time to Shine: An Acorn Book (Fairylight Friends #2)Full Moon Party: An Acorn Book (Fairylight Friends #3)Travel to a magical moonlit party with fairy friends Ruby, Iris, and Pip in this wondrous early reader series!Pick a Book. Grow a Reader!This series is part of Scholastic's early reader line, Acorn, aimed at children who are learning to read. With easy-to-read text, a short-story format, plenty of humor, and full-color artwork on every page, these books will boost reading confidence and fluency. Acorn books plant a love of reading and help readers grow!Best friends Ruby, Iris, and Pip are on their way to a full moon party! In five dazzling stories, the fairy friends use their powers to create their own ride, play fun games to win prizes, and have a dance party! With easy-to-read text and charming full-color artwork throughout, this series is perfect for beginning readers!

只能跑出統計報表的統計套裝軟體落伍了，讓統計專家以及程式高手帶著您，透過AI來幫您做統計計算、分析與解讀！R語言是進入統計學領域的一把重要鑰匙，本書從基礎開始，一個個步驟帶您領會運用R語言的樂趣。R 是一種專門為統計分析與資料管理所設計的手稿語言。R 誕生於90 年代初期，由S 語言所轉變而來。它是免付費的公開軟體，可自由下載原始碼，加上十分容易在官方網站找到別人寫好的套件或分析程式碼，因此近年來使用的人越來越多，並且不乏許多專業人士如：風險分析師、研究學者、統計學家等。本書會從入門的安裝步驟開始，介紹R的資料型態、資料整理、繪圖、推論統計的概念、變異數分析等，幫助讀者打好基礎，讀完您會發現，原來統計就是這麼輕鬆啊！

Moby Shinobi and Toby, Too! An Acorn Book (Book 1-3)Moby Shinobi and his sidekick Toby are heading to the beach in this action-packed, rhyming early reader!Pick a book. Grow a Reader!This series is part of Scholastic's early reader line, Acorn, aimed at children who are learning to read. With easy-to-read text, a short-story format, plenty of humor, and full-color artwork on every page, these books will boost reading confidence and fluency. Acorn books plant a love of reading and help readers grow!Moby Shinobi and his dog Toby are excited for a day at the beach! Moby tries to use his ninja skills to build a huge sand castle, catch some fish, and save a leaking sailboat... but each try ends in a mess! What if Moby isn't right for the job? But with some help from Toby, he discovers that teamwork makes every job easier! With easy-to-read rhyming text and full-color artwork throughout, this early reader series is sure to be a hit with beginning readers!

YA！我喜歡統計學！R語言版來了！你也許常聽到「統計學好難喔」、「念統計有什麼用」這樣的話，那只是很少人發現統計學的魅力，這本書將顛覆你的刻板印象！外表看似枯燥又艱深，骨子裡卻是有趣又實用，講解觀念親切生動，讓你一不小心就愛上統計學了。※每章均附「真實世界的統計」，讓你知道統計其實默默地貼近你的生活。※互動式學習網站加深你與統計學的情感連結。※本書附有資料檔，請至五南官網輸入本書書號，即可找到資料

NEW YORK TIMES BESTSELLERNow in paperback--Peggy Orenstein, author of the groundbreaking New York Times bestseller Girls & Sex, turns her focus to the sexual lives of young men. "Eye-opening.... Every few pages, the boy world cracks open a little bit.... Even in the most anxiety-provoking moments of Boys & Sex, it's clear that Orenstein believes in the goodness of boys and the men they can become, and she believes in us, as parents, to raise them" (New York Times Book Review).Peggy Orenstein's Girls & Sex broke ground, shattered taboos, and launched conversations about young women's right to pleasure and agency in sexual encounters. It also had an unexpected effect on its author: Orenstein realized that talking about girls is only half the conversation. Boys are subject to the same cultural forces as girls--steeped in the same distorted media images and binary stereotypes of female sexiness and toxic masculinity--which equally affect how they navigate sexual and emotional r

In the late 19th and early 20th century, a combination of coastal defence for the homeland and fleet defence for the East Indies became the established naval strategy for the Royal Dutch Navy and set

大數據(Big Data)，爆紅速度僅次於雲端運算。近年來，雲端運算雖然還是很熱門的話題，但更熱門的是Big Data，情況就像幾年前廠商不約而同在談雲端運算一樣。大數據已成為目前全球學術單位、政府機關以及頂級企業必須認真面臨的挑戰，隨著有關大數據的程式語言、運算平台、基礎理論，以及虛擬化、容器化的技術成熟，了解大數據的原理、實作、工具、應用以及未來趨勢，都將會是求學、進修、求職、深造的必備技能。