Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

School is in session for the ocean's crankiest crab!Pick a book. Grow a Reader!This series is part of Scholastic's early reader line, Acorn, aimed at children who are learning to read. With easy-to-read text, a short-story format, plenty of humor, and full-color artwork on every page, these books will boost reading confidence and fluency. Acorn books plant a love of reading and help readers grow!It's just another day in the ocean for Crabby and Plankton -- until they find themselves INSIDE a school of fish! This gives Plankton a fabulous idea -- he and Crabby should play school! But Crabby doesnotwant to play. In four hilarious stories, Crabby uses funny wordplay to distract Plankton from teaching, until finally he gives up and declares, "School is OUT, Crabby!"With comic speech bubbles and full-color artwork throughout, Geisel Award Honoree Jonathan Fenske's early reader series is sure to be a hit with new readers!

The Positive Power early reader series introduces self esteem and empathy to budding young readers. I Am Thankful is a fun and encouraging early reader about all the things we have to be thankful for! Now a part of the premier early reading line, Step into Reading!It's Thanksgiving, and there's a lot to be done before turkeytime! A young boy has plenty of autumn adventures, from running in the turkey trot to helping his family bake pies. But then the weather threatens to ruin the annual family football game! Luckily, the jam-packed day proves there's never a shortage of things to be thankful for. In this installment of the Positive Power series, kids will learn the affirmation "I am thankful" through a delightful story of food, family, and fun.Through simple text and joyful illustrations, this installment in the Positive Power series inspires kids to help others while giving them the confidence they need to transform from little to BIG readers. Step 2 Readers use basic vocabulary and s

The link between corporate social responsibility and financial performance in Taiwan：A non-linear approachCognitive complexity, stylistic innovation and performance： A preliminary study of small taiwanese design firmsA bibliometric analysis on emerging technology research and development

Fox Tails #1-3: An Acorn BookThe Great Bunk Bed Battle: An Acorn Book (Fox Tails #1)The Biggest Roller Coaster: An Acorn Book (Fox Tails #2)The Giant Ice Cream Mess: Acorn Book (Fox Tails #3)Siblings Fritz and Franny have their sights set on the tastiest ice cream treat in this early reader from Geisel Honor winner Tina Kügler!Pick a Book. Grow a Reader!This series is part of Scholastic's early reader line, Acorn, aimed at children who are learning to read. With easy-to-read text, a short-story format, plenty of humor, and full-color artwork on every page, these books will boost reading confidence and fluency. Acorn books plant a love of reading and help readers grow!Scoop up this fun-filled early reader series! When competitive fox siblings Fritz and Franny hear the ice cream truck on their street, they both imagine making the sweetest treat with different flavors and toppings. But there's just one problem: Their mom says they can only have one scoop each! Maybe Fritz and Franny need

This clever graphically illustrated book explores above, below, among and other early concepts through the eyes of a mouse searching to become “more than one.”

Mr. Wolf's class might be going home early It's snowing, and there's excitement in the air at Hazelwood Elementary because the school day might end early. Students and teachers alike are looking forward to seeing what happens Meanwhile, Abdi is distracted and worried because his brother is having surgery. He's supposed to go home with Henry, but when the two miss the bus, they end up having an unexpected adventure with Mr. Wolf

《遊戲人生》進階版！ 「教學現場的魔法師」莊越翔老師首本遊戲寶典。陪你一起善用遊戲，活化人生，遊戲成精。 《遊戲人生》作者楊田林老師喻為「帶領遊戲的奇才」──莊越翔老師，演講場次逾千場，近15,000讚友推薦。進階玩法，靈活應用，讓教學現場好好玩！ 遊戲專業想‧活動專業想‧創意專業想 全書共8大主題，吸睛活動72變──R促進人際互動 R體驗遊戲樂趣 R現場引導反思R實體課程說明 R線上帶動分享 R延伸活動變化 從人間四季春夏秋冬，隱喻遊戲帶動熱身、激發學員熱情、建立共識、安頓整理四大節奏。這本書，教的不只是遊戲，是人生！ 傳承推薦____《遊戲人生》作者楊田林 企業人文講師專文推薦（依筆畫序）____張志成 中華康輔教育推廣協會創會理事長｜張忘形 溝通表達培訓師｜黃同慶 世界五百強企業顧問／職業企管講師｜葉丙成 臺大教授｜歐耶 起初文創表達訓練總監／即興脫口秀演員｜歐陽立中 暢銷作家／Super教師｜蔡居澤 師範大學公民教育與活動領導學系副教授暨系主任 名人推薦（依筆畫序）____阿滴 百萬Youtuber／阿滴英文創辦人｜王漢克 實境解謎培訓師｜曲智鑛 陶璽工作室創辦人｜李姵儀 育圃教育執行長｜林佳諭 中興國中教師｜邱建智 中華康輔教育推廣協會副理事長｜南瓜妹 共玩創新共同創辦人｜洪瑞聲 遊戲學習設計師｜連育仁 中原大學應用華語文學系副教授｜陳志恆 諮商心理師｜趙胤丞 專職講師｜黎孔平 玩轉學校共同創辦人｜賴以威 師範大學電機工程學系副教授

Join Crab and Snail in the surf zone, where they think deep thoughts and have unforgettable seaside adventures, in this graphic early reader series debut by New York Times bestselling author Beth Ferry and beloved illustrator Jared Chapman.The never-ending rain is putting a damper on Crab and Snail's plans for a sunny, funny day. So when the BBFs (Best Beach Friends) realize that it's only raining on them, they put their heads together and consult one know-it-all gull (he really does know it all!) to get to the bottom of it. By the time the rain clears, the duo will have made a new friend and learned something new and wonderful about friendship!Crab and Snail are everyone's next favorite characters in the graphic early reader space. Fans of Narwhal & Jelly; Pea, Bee, & Jay; and Arlo & Pips will love these quirky characters and clever stories.

The Positive Power series introduces self esteem and empathy to budding young readers. I Am Brave is a fun and encouraging story about facing your fears! Now a part of the premier early reading line, Step into Reading!Sometimes new experiences can feel scary. I Am Brave follows a little girl as she goes on a big vacation, complete with a first airplane ride, a giant water slide at the hotel, and a spooky cave--with bats! Thankfully, with her brother, parents, and even a magician as guides, she learns to lt her courage shine and embrace new adventures! In this installment of the Positive Power early reader series, children will learn the affirmation "I am brave" through an encouraging story of exploration and overcoming anxiety. Step 2 Readers use basic vocabulary and short sentences to tell simple stories, for children who recognize familiar words and can sound out new words with help. Rhyme and rhythmic text paired with picture clues help children decode the story.Series Overview

The Positive Power series introduces self esteem and empathy to budding young readers. I Am Kind is a fun and encouraging story about the power of kindness! Now a part of the premier early reading line, Step into Reading!A little girl sees kindness all around her. Her mother is kind when she volunteers in the community, and her neighbor is kind when he gives her strawberries from his garden. The little girl realizes that she, too, has the power to be kind. Even small actions can have a big impact! In this installment of the Positive Power early reader series, children will learn the affirmation "I am kind" through an encouraging story of community and everyday kindness. Step 2 Readers use basic vocabulary and short sentences to tell simple stories, for children who recognize familiar words and can sound out new words with help. Rhyme and rhythmic text paired with picture clues help children decode the story.Series Overview: Since 1984, Step into Reading has set the standard. Random Hou

Unicorn and Yeti are two magical friends who love using their imaginations Pick a Book. Grow a Reader This series is part of Scholastic's early reader line, Acorn, aimed at children who are learning to read. With easy-to-read text, a short-story format, plenty of humor, and full-color artwork on every page, these books will boost reading confidence and fluency. Acorn books plant a love of reading and help readers grow Unicorn and Yeti look up at the sky. Clouds take on all sorts of fun shapes Unicorn wants to do everything Yeti does. Will Yeti have fun playing with a copycat? Unicorn wants to have a fancy tea party. But Yeti just wants to drink tea Best friends Unicorn and Yeti have big imaginations, and they have lots of fun together. These laugh-out-loud stories with full-color artwork, speech bubbles, and easy-to-read text throughout are perfect for new readers

Celebrate Easter with the Berenstain Bears in this new My First I Can Read!It's springtime in Bear Country and the Berenstain Bears are excited to celebrate Easter! Colored eggs, sweet goodies, and beautiful flowers help make the holiday beloved. But when the Easter Bunny fails to deliver eggs on this special day, it's up to the Bears to save the holiday!Beginning readers will enjoy this fun holiday tale about their favorite family of bears. This My First I Can Read book is carefully crafted using basic language, word repetition, sight words, and sweet illustrations--which means it's perfect for shared reading with emergent readers. The active, engaging My First I Can Read stories have appealing plots and lovable characters, encouraging children to continue their reading journey.

The This is line of World of Reading early readers is designed to offer reluctant readers books they will want to read by featuring the origin stories of characters they love.Introducing Doctor Strange and Scarlet Witch! They come from different backgrounds, but Doctor Strange and Scarlet Witch have one very important thing in common: Magic. These two heroes use their powers to help others whenever they need it most.Learn how Doctor Strange and Scarlet Witch use their magical abilities to save the day in this 32-page story.

Wry, witty and very funny diary-style story packed with doodles and comic strips about the frustration trickster god Loki feels at having to live trapped in the body of a weedy eleven-year-old boy. After one trick too many, Loki is banished to live on Earth as a "normal" school boy. Forbidden from using his AWESOME godly powers, Loki must show moral improvement.As he records his lies THE TRUTH in his magical (judgemental) diary, it becomes clear Loki hasn't a clue how to tell good from evil, trust from tricks, or friends from enemies.

◎The first book in the world detailing the development history and clinical application of plasma exchange in solving aging problems.◎Heterochronic Parabiosis is science, not medical.◎If you are struggling with aging problems, this book will help you understand the root cause of the problems.◎代理經銷：白象文化更多精彩內容請見http://www.pressstore.com.tw/freereading/9786267018729.pdf

Harry gets a new toy car in this adorable early reader perfect for fans of Frog and Toad Pick a book. Grow a Reader This series is part of Scholastic's early reader line, Acorn, aimed at children who are learning to read. With easy-to-read text, a short-story format, plenty of humor, and full-color artwork on every page, these books will boost reading confidence and fluency. Acorn books plant a love of reading and help readers grow Harry's new toy car has arrived in the mail and he cannot wait to play with it His best friend Hedgehog wants to play with it, too. Hedgehog asks Harry for a turn and Harry agrees. But Harry discovers that sharing his awesome new toy is going to be harder than he thought... These warm, laugh-out-loud stories with full-color artwork, speech bubbles, and easy-to-read text throughout are perfect for new readers

Bo discovers friendly yetis in this early chapter book from the USA Today bestselling author of Owl Diaries Pick a book. Grow a Reader This series is part of Scholastic's early chapter book line, Branches, aimed at newly independent readers. With easy-to-read text, high-interest content, fast-paced plots, and illustrations on every page, these books will boost reading confidence and stamina. Branches books help readers grow In the sixth book of USA Today bestselling author Rebecca Elliott's Unicorn Diaries series, unicorn Bo and friends set out to explore Snowbelle Mountain and maybe run into some yetis Bo and their friends disagree about the best way to go about their adventure, and Bo ultimately learns to appreciate living in the moment. With full-color artwork throughout and plenty of smiles, your young reader won't be able to put this book down

Discover how geology is part of our daily lives with Everyday STEM Science: Geology. Explore the wonders of Earth and see how geology is all around us, from natures materials that are used to build roads and buildings to the minerals found in your mobile phone and drinks can. Witness a volcanic eruption, find out if there is water on Mars, unearth a dinosaur and meet the geologists and scientists who brought geology to life. Readers can also carry out geology experiments at home. With easy-to-understand text written by Emily Dodd, fun callouts and lots of colourful artworks, photos, and diagrams, readers can best explore where we encounter geology and why it’s even important at all. The Everyday STEM series makes STEM relevant to tweens. Instead of telling kids STEM is important and is the key to their “future success,” these books, including Everyday STEM Science – Physics, show readers how we use science, technology, engineering and maths in our everyday lives. While the topics sound

Explore one of the most powerful and highest-ranking female figures in American history with this biography of Vice President Kamala Harris in this Level 2 reader.On January 20, 2021, Kamala Harris made history. That day, she became the first woman, the first Black American, and the first South Asian American to be elected as Vice President of the United States. Young readers will learn about Harris’s childhood, her early career, and her journey that led to winning the vice presidency. This early reader also explores how Harris devoted her life to helping others, from serving as the Attorney General of California, to being elected as a U.S. Senator, to working alongside President Joe Biden on the campaign trail and in the White House.The level 2 text provides accessible, yet wide-ranging information for independent readers. Explore Harris’s life, achievements, and the challenges she faced along the way to becoming a barrier-breaking leader and an inspiration to young people everywhere.

Give your kindergartner a strong computer science foundation with Smart Start: Beginning Coding Stories and Activities. Children will learn important coding concepts with engaging stories and practice activities. Based on the K-12 Computer Science Framework, this dynamic early learning series helps children understand coding concepts to develop a strong foundation in computer science, including computational thinking, problem solving, and critical thinking. Each full-color activity book is organized into eight themed units around one coding concept and includes: - Coding stories that demonstrate what coders do and include an audio read-aloud feature - Concept pages that connect coding concepts to real-world situations - Practice activities that reinforce important coding rules - Review pages for every coding concept practiced - Coding projects with print-based games and puzzles - Mini coding handbook with key terms Computer science concepts and skills help early learners become critica

Give your first grader a strong computer science foundation with Smart Start: Beginning Coding Stories and Activities. Children will learn important coding concepts with engaging stories and practice activities. Based on the K-12 Computer Science Framework, this dynamic early learning series helps children understand coding concepts to develop a strong foundation in computer science, including computational thinking, problem solving, and critical thinking. Each full-color activity book is organized into eight themed units around one coding concept and includes: - Coding stories that demonstrate what coders do and include an audio read-aloud feature - Concept pages that connect coding concepts to real-world situations - Practice activities that reinforce important coding rules - Review pages for every coding concept practiced - Coding projects with print-based games and puzzles - Mini coding handbook with key terms Computer science concepts and skills help early learners become critical

A Magic Spark: An Acorn Book (Fairylight Friends #1)Time to Shine: An Acorn Book (Fairylight Friends #2)Full Moon Party: An Acorn Book (Fairylight Friends #3)Travel to a magical moonlit party with fairy friends Ruby, Iris, and Pip in this wondrous early reader series!Pick a Book. Grow a Reader!This series is part of Scholastic's early reader line, Acorn, aimed at children who are learning to read. With easy-to-read text, a short-story format, plenty of humor, and full-color artwork on every page, these books will boost reading confidence and fluency. Acorn books plant a love of reading and help readers grow!Best friends Ruby, Iris, and Pip are on their way to a full moon party! In five dazzling stories, the fairy friends use their powers to create their own ride, play fun games to win prizes, and have a dance party! With easy-to-read text and charming full-color artwork throughout, this series is perfect for beginning readers!

只能跑出統計報表的統計套裝軟體落伍了，讓統計專家以及程式高手帶著您，透過AI來幫您做統計計算、分析與解讀！R語言是進入統計學領域的一把重要鑰匙，本書從基礎開始，一個個步驟帶您領會運用R語言的樂趣。R 是一種專門為統計分析與資料管理所設計的手稿語言。R 誕生於90 年代初期，由S 語言所轉變而來。它是免付費的公開軟體，可自由下載原始碼，加上十分容易在官方網站找到別人寫好的套件或分析程式碼，因此近年來使用的人越來越多，並且不乏許多專業人士如：風險分析師、研究學者、統計學家等。本書會從入門的安裝步驟開始，介紹R的資料型態、資料整理、繪圖、推論統計的概念、變異數分析等，幫助讀者打好基礎，讀完您會發現，原來統計就是這麼輕鬆啊！

An illustrated adaptation of Sir Arthur Conan Doyle's classic Sherlock Holmes mystery – at an easy-to-read level for readers of all ages! Also includes a QR code for the free audiobook!You should write about the case of the Devil’s Foot. I am sure your readers would love to hear about the day we almost died. HolmesAll Watson wants is a nice quiet holiday with Holmes, but that’s not what he’s getting.When Brenda Tregennis is found dead at her dinner table, with no clues as to how or why, all eyes turn to the detective duo to solve the mystery. With deadly experiments, lethal poisons and a suspicious explorer to deal with, there’s no time for relaxation!

An illustrated adaptation of Sir Arthur Conan Doyle's classic Sherlock Holmes mystery – at an easy-to-read level for readers of all ages! Also includes a QR code for the free audiobook!Mr McPherson shook his head, squeezed his hands into tight fists and, using the last of strength, said: ‘The lion’s mane’. Retired now and living in Sussex, Holmes’ life should be perfectly peaceful. But when a local teacher drops dead in front of him, Holmes is thrown back into the world of dangerous detective work.With multiple suspects, mysterious wounds and no Watson around to help him, Holmes is going to be pushed to his limits to solve this strange case.

The first in an early graphic novel series about outgoing Cookie and shy Broccoli as they navigate the ups and downs of starting school--perfect for fans of Narwhal and Jelly! New best friends Cookie

Best friends Cookie and Broccoli take on popularity and overcoming obstacles together through kindness and laughter in this cheerful early graphic novel that's perfect for fans of Narwhal and Jelly. C

Packed with simple craft and cooking activities with a Christmassy theme, using things you'll easily find to hand about the house. Make everything from garlands and gift tags to reindeer snacks and wr

───唯一清零，守護健康最後防線─── STOP！食癮風暴 肥胖問題，成了慢性病幕後元凶， 癌症、腦心血管疾病、糖尿病通通屬於「肥胖併發症」！? 斷開──肥胖、代謝症候群、第二型糖尿病、腦心血管疾病及癌變 R中年發福，三高、慢性病的元凶？ R糖尿病，可以完整控制的契機？ R高血糖讓血管泡糖水，恐致失明、足病變？ R減肥又復胖，溜溜球效應？ R高胰島素血症，引發致命危機？ ➤血管油滋滋，小心猝死風險高！ 肥胖會破壞心血管保護機制，導致「心肌梗塞」與「腦中風」合稱的腦心血管疾病，每年奪走將近兩千萬條生命！ ➤井噴式成長，富貴病成平民病？ 肥糖尿病由早期的「富貴病」，變成人人可得的「平民病」，三分之一的洗腎病患來自於糖尿病併發症，食癮風暴儼然成為國安危機。 代謝矯正技術，成功逆轉食癮風暴！ STOP！食癮風暴 成人代謝症候群防治破口，由此開始！ 感動見證．各界好評從小就是肉肉身材，沒想到也有變瘦變美的時候，短短一個月少了5.4公斤，也帶我遠離糖尿病的危害。 ──台中．雅雯 代謝矯正技術幫我管好胰島素，成功擺脫呼吸也會胖的惡夢，睡眠問題也跟著不藥而癒。 ──家庭主婦．可欣 矯正身體代謝異常，讓我不用再當藥罐子，不只成功減重，也成了糖尿病的拒絕往來戶。 ──上班族．渝雯 理論實證．專業推薦振興醫院新陳代謝科 石光中 醫師 前陽明醫學院院長 何橈通 醫師 竹圍鴻恩家醫科診所 李天行 院長 （依姓名筆劃排序） 現在起，一起邁向「胰島素5.0」── ◎追求健康：胰島素5.0！ ◎想要苗條身材：胰島素5.0！ ◎消除水桶腰，鮪魚肚：胰島素5.0！ ◎不想得糖尿病：胰島素5.0！ ◎拒絕中風，心肌梗塞：胰島素5.0！ ◎遠離大腸癌：胰島素5.0！ ◎讓自己健康又長壽：胰島素5.0！

This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface.We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

A fifth Branches early chapter book featuring everyone's favorite pug, Bub, and his human, Bella!Pick a book. Grow a Reader!This series is part of Scholastic's early chapter book line, Branches, aimed

Super Facts for Super Kids is a fun, fresh take on animal nonfiction for beginning readers. Filled with engaging photographs, comic-style illustrations, and cool infographics, these Level 2 Ready-to-R

「可靠性」是系統與產品所不可欠缺的時間品質，在物美價廉的產品之中，賦予能與成本保持均衡的「可靠性（R）／維護性（M）」，正是品質保證上所需要的要件。隨著品質走向品質保證的地步，可靠性在品質保證所擔負的功能有與日俱增之勢。由於「品管（QC）」是產品或系統所不可或缺的空間品質，而「R／M」則是不可欠缺的時間品質，因之「QC」與「R／M」在產品的品質保證上相得益彰、如虎添翼。本書有別於一般以數理的方式探

Moby Shinobi and Toby, Too! An Acorn Book (Book 1-3)Moby Shinobi and his sidekick Toby are heading to the beach in this action-packed, rhyming early reader!Pick a book. Grow a Reader!This series is part of Scholastic's early reader line, Acorn, aimed at children who are learning to read. With easy-to-read text, a short-story format, plenty of humor, and full-color artwork on every page, these books will boost reading confidence and fluency. Acorn books plant a love of reading and help readers grow!Moby Shinobi and his dog Toby are excited for a day at the beach! Moby tries to use his ninja skills to build a huge sand castle, catch some fish, and save a leaking sailboat... but each try ends in a mess! What if Moby isn't right for the job? But with some help from Toby, he discovers that teamwork makes every job easier! With easy-to-read rhyming text and full-color artwork throughout, this early reader series is sure to be a hit with beginning readers!

Introducing I Can Read Comics, a brand-new early reader line that familiarizes children with the world of graphic novel storytelling and encourages visual literacy in emerging readers.Meet the robots

Learn about animals in this early learning activity book. Big Stickers for Little Hands Animals introduces children to the animal world through simple activities, big stickers and card press-outs. Eac

In this charming trip of the imagination, a little girl delights in experiencing life at a slower pace as she shares her day with a sleepy sloth who moves so slowly, moss grows in his fur! This sloth may be sleepy but it's a champion on the jungle gym, thanks to its super gripping skills. And climbing trees has never been so easy! But the little girl's hairdresser is less than impressed to find not just moss but also moths in its fur - and by the time our sleepy sloth has finished its morning walk, the day is almost done. Through rollicking rhymes and bold, graphic illustrations, If I had a sleepy sloth imagines the positives and negatives of having a sloth for a pet and provides a welcome alternative to the fast pace of modern life by creating the time for readers to simply b-r-e-a-t-h-e.

YA！我喜歡統計學！R語言版來了！你也許常聽到「統計學好難喔」、「念統計有什麼用」這樣的話，那只是很少人發現統計學的魅力，這本書將顛覆你的刻板印象！外表看似枯燥又艱深，骨子裡卻是有趣又實用，講解觀念親切生動，讓你一不小心就愛上統計學了。※每章均附「真實世界的統計」，讓你知道統計其實默默地貼近你的生活。※互動式學習網站加深你與統計學的情感連結。※本書附有資料檔，請至五南官網輸入本書書號，即可找到資料

這是一本前沿的定性比較分析（QCA）方法工具書，是通過R語言實現定性比較分析的一個全面指南。QCA方法的獨特之處在於結合了定性方法與定量方法的特點，已成為近年來國外社會學、管理學、營銷學、政治學、傳播學等領域的學者進行開創性研究的“第三條道路”。QCA方法適用範圍廣泛，既可以用於小樣本的案例研究（彌補案例研究的外部推廣性差的缺陷），也可以用於大樣本的數據分析（彌補大樣本研究缺乏定性判斷和對於複雜因

NEW YORK TIMES BESTSELLERNow in paperback--Peggy Orenstein, author of the groundbreaking New York Times bestseller Girls & Sex, turns her focus to the sexual lives of young men. "Eye-opening.... Every few pages, the boy world cracks open a little bit.... Even in the most anxiety-provoking moments of Boys & Sex, it's clear that Orenstein believes in the goodness of boys and the men they can become, and she believes in us, as parents, to raise them" (New York Times Book Review).Peggy Orenstein's Girls & Sex broke ground, shattered taboos, and launched conversations about young women's right to pleasure and agency in sexual encounters. It also had an unexpected effect on its author: Orenstein realized that talking about girls is only half the conversation. Boys are subject to the same cultural forces as girls--steeped in the same distorted media images and binary stereotypes of female sexiness and toxic masculinity--which equally affect how they navigate sexual and emotional r