Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Get ready to explore the city! Dominika Lipniewska takes us on a magical journey through a day in the life of a city. With bold and distinctive graphics and lots of detail for children to explore, In

Who built the first houses? What's the difference between an arch and an architrave? How does a dome stay up? Who invented concrete? Can you build a house from paper? If you want to know more about the buildings around you, this entertaining illustrated guide is a perfect introduction to architecture around the world. From the mud huts of ancient history to today's towering edifices, you can explore iconic buildings and find out more about the people who created them. You'll also discover the development of different building materials, from mud and straw to paper, steel and reinforced concrete.AGES: 5 to 11 AUTHORS: Eduard Altarriba is a graphic designer and illustrator. He runs Alababala, a Barcelona-based independent studio producing games, exhibitions, animation, apps and workbooks for children that are practical and fun. Other books he has worked on include My First Book of Quantum Physics, also published by Button Books.Berta Bardi i Mila is a Lecturer at the School of Architectu

Postwar Hong Kong cinema played an active role in building the colony’s community in the 1950s and 1960s. To Jing Jing Chang, the screening of movies in postwar Hong Kong was a process of showing the

What can you do in a minute? Blink 20 times? Do 77 star jumps? Or hoover up 24 ants, if you're a hungry anteater! In a Minute is a clever way to think about time. With engaging contemporary illustrati

`IT ARRIVED ONE MORNING WHEN NO-ONE WAS LOOKING' It unexpectedly arrived. It brushed past someone in the street. It weaves its way in and out of people on the street. It catches people completely unaw

"Applaud for KLAWDE. Two paws up!"--Dav Pilkey, creator of the Dog Man series.Klawde is not your average cat. He's an emperor from another planet, exiled to Earth. He's cruel. He's cunning. He's brilliant... and he's about to become Raj Banerjee's best friend. Whether he likes it or not.Klawde had everything. Sharp claws. Fine fur. And, being the High Commander of the planet Lyttyrboks, an entire world of warlike cats at his command. But when he is stripped of his feline throne, he is sentenced to the worst possible punishment: exile to a small planet in a quiet corner of the universe... named Earth. Raj had everything. A cool apartment in Brooklyn. Three friends who lived in his building. And pizza and comics within walking distance. But when his mom gets a job in Elba, Oregon, and he is forced to move, all of that changes. It's now the beginning of summer, he has no friends, and because of his mother's urgings, he has joined a nature camp.It's only when his doorbell rings and he meet

See the human body as never before, in this unique scratch and discover format. Every spread addresses a new theme, teaching little ones about about our skeletons, muscles and brains! An appealing, in

Three hundred years ago, fate bound Prosper Redding and Prince Alastor of the Third Realm together. Now the human boy and fiend heir to the demon kingdom must put aside a centuries-old blood feud to save everything they love. Alastor will guide Prosper through the demon realm-under one huge condition: Prosper must enter into a contract with the malefactor residing in him, promising eternal servitude in the afterlife. With Prosper's sister in the clutches of the evil queen Pyra, Prosper has no choice but to agree. But when they arrive in Alastor's deliciously demonic home, the realm is almost as alien to Alastor as it is to Prosper-the lowest fiends have dethroned the ruling malefactors, while an unfathomable force called the Void is swiftly consuming the realm. The desperate fiends cling to the one person who says she can stop it: Pyra. As Prosper embarks on a perilous rescue mission to the Tower of No Return, he can't help but feel for the demons losing their home-even Alastor, who li

Heave ho! Set sail on a high-seas adventure with swashbuckling pirates in search of treasure in this new MagnetologyTM title. Kids can use the forty-five magnetic pieces included to fill five dramatic

New in the Little People, Big Dreams series, discover the life of Muhammad Ali, 'the greatest' boxer of all time, in this true story of his life. As a child, young Cassius Clay had his bike stolen. He

The holocaust will remain a stain on the history of mankind in perpetuity, long after the recollection of many of the perpetrators has faded. Some names will remain, however, indelibly printed in the

The publication of this book marks the fifteenth anniversary of the outbreak of SARS epidemic in Hong Kong in 2003. This documentary study, originating as a research project a year after the epidemic,

The Crown Jewels are in danger... again! When the jewels go missing from inside a locked room, Mac's spy skills are put to the test. How did the thief break in? Where did the jewels go? And will Mac b

In their analyses of the role of women in politics, political scientists had tended to neglect the family and the labour market, thus ignoring a crucial aspect of women's political activity. Originall

A game of hide-and-seek in the forest might lead to unexpected discoveries. Could there be something hidden in the trees?When their dog goes missing, siblings Poppy and Cy decide to play hide-and-seek

Imagine a human society, perhaps in pre-history, in which people were generally of a psychological kind with us, had the use of natural language to communicate with one another, but did not have any p

In the first part of the twentieth century, Korean Buddhists, despite living under colonial rule, reconfigured sacred objects, festivals, urban temples, propagation—and even their own identities—to modernize and elevate Korean Buddhism. By focusing on six case studies, this book highlights the centrality of transnational relationships in the transformation of colonial Korean Buddhism.Hwansoo Ilmee Kim examines how Korean, Japanese, and other Buddhists operating in colonial Korea, Japan, China, Taiwan, Manchuria, and beyond participated in and were significantly influenced by transnational forces, even as Buddhists of Korea and other parts of Asia were motivated by nationalist and sectarian interests. More broadly, the cases explored in the The Korean Buddhist Empire reveal that, while Japanese Buddhism exerted the most influence, Korean Buddhism was (as Japanese Buddhism was itself) deeply influenced by developments in China, Taiwan, Sri Lanka, Europe, and the United States, as well as

Did you know there are over 47,000 facts in the world?* And the good news is, many of them are in this book. That’s right, The Grand Tour A-Z of the Car is the only reference guide you need for cars,

Celebrate the world of dinosaurs in this alphabet of exquisite pop-ups. From the allosaurus to the zuniceratops, discover dinosaurs great and small in this prehistoric pop-up alphabet. Featuring a sel

A groundbreaking graphic novel-style cocktail book from world-renowned bar The Dead Rabbit in New York City The Dead Rabbit Grocery & Grog in lower Manhattan has won every cocktail awa

Join two unlikely friends (and one cleverly hidden ladybug), as they discover that anything is possible when you believe in yourself - and each other.When a potted houseplant is placed down in a room

Join your favorite Disney characters for six bedtime stories in one soft, snuggly book.

Born into a Jewish family in Frankfurt, Germany, in 1929, Anne Frank was only thirteen years old when her family went into hiding to escape persecution during the Holocaust. Anne kept a diary detailin

Much more than a history atlas, this ?book drops you right in the heart of the action, as 130 detailed maps tell the story of pivotal episodes in world history, from the first human migrations out of

A foolish knight is certain that his side of the wall is the safe side in this clever, amusingly meta picture book by the acclaimed creator of It's Only StanleyThere's a wall in the middle of the book

Best friends Little Elliot and Mouse go looking for Christmas spirit in this winter holiday picture book.

Journey back through childhood classics like Peter Pan, Alice's Adventures in Wonderland, and more in this adorable picture book about the joys of reading!There is nothing like a book to take you to p

On a crisp autumn day Mouse and Minka celebrate fall by jumping in a pile of leaves in this adorable Pre-Level 1 Ready-to-Read book about fall!One cool fall day, Mouse and Minka come out to play! They

Christina Rossetti (1830-94) is regarded is one of the greatest Christian poets to write in English. While Rossetti has firmly secured her place in the canon, her religious poetry was for a long time

This playful preschool activity book will unleash your child's curiosity and creativity as they play their way through amazing STEM projects.Perfect for kids ages 3-6, this early learning children's book will excite little ones by revealing the everyday ways they can be an engineer. Children are born with everything they need to be great engineers: inquisitive minds, unlimited imagination, and super senses. With Look I'm an Engineer, little readers are encouraged to use their senses to investigate how to make the strongest paper bridges, how to power a tugboat with an elastic band, which materials make the best parachutes, and much more. Every fun project features a mixture of bright photography and charming illustrations which support the easy-to-follow activity instructions. These wonderful hands-on activities align with subjects taught at school, including science, math, and technology. Little ones have the opportunity to do what they do best: imagine, create, learn, problem solve,

New in the Little People, Big Dreams series, discover the incredible life of Mother Teresa, in this true story of her life. With stylish and quirky illustrations and extra facts at the back, this empo

New in the Little People, Big Dreams series, discover the life of Anne Frank, the writer whose diary captured the hearts of the public, in this true story of her life. Little Anne was born in Germany

There is no single masterpiece in art galleries or with people—we’re all works of art in our own special way! Our skin tones might all vary;we're every shade and hue.Some people think we look surreal,

New in the Little People, Big Dreams series, discover the life of Anne Frank, the writer whose diary captured the hearts of the public, in this true story of her life. Little Anne was born in Ger

This guidebook is for college instructors who teach a course in Introduction to Logic at a teachers college or provide a workshop in this subject for in-service mathematics teachers. It can also be us

Autumn leaves aren’t the only things falling in the historic Virginia village of Taylorsford—so are some cherished memories, and a few bodies. October in Taylorsford, Virginia means it’s leaf peeping

Children all over the world are very different, but they also have much in common. In this beautifully illustrated book, young children can learn all about what people in other countries eat, wear and

The first woman to fly solo across the Atlantic Ocean, Amelia Earhart was a superstar of aviation in the 1920s and 1930s and a pioneer of women's rights. Her disappearance in 1937, while attempting to

On a bright sunny day Mouse and Minka celebrate summer with a picnic in the park in this beautiful Pre-Level 1 Ready-to-Read book about summer!One sunny summer day, Mouse and Minka head outside to pla

The Origins of a Legendary PhotographerAnnie Leibovitz's photographic breakthrough and Rolling Stone reportageFor more than half a century, Annie Leibovitz has been taking culture-defining photographs