Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Discover the wild side of cities around the world in this stunning collection of urban maps. Did you know that there are flying squirrels in the heart of New York City? Or that wild boar roam the stre

Book three in the charming Chirri & Chirra series, here we have foxes, bears, birds, goats, and cats all taking shelter together in an icy cavern, enjoying everything from freshly-baked delights t

In The Rime of the Ancient Mariner, one of the best-known and best-loved poems in the English language, a grizzled old sailor stops a man on his way to a wedding and tells a terrifying story. He speak

A baby is found by wood nymphs in the forest of Burzee. They raise him as their own and give him the name Neclaus. When he grows up, Neclaus has to leave the forest so he makes a home for himself in t

The pig lives in a house in the middle of the wild wood. But inside the wild wood there's a bad wolf - and this hungry wolf wants a little pig for dinner! But a house made of bricks is hard to blow do

At the age of six, little orphan Heidi is sent to live with her grandfather in the Alps. Everyone in the village is afraid of him, but Heidi - fascinated by his long beard and bushy grey eyebrows – ta

English gentleman, Rupert Rassendyll, arrives in the kingdom of Ruritania on the eve of King Rudolf’s coronation. That night the king is abducted and held prisoner in a castle in the small town of Zen

The third Duck, Duck, Porcupine book has a new trio of stories featuring loud and in-charge Big Duck, quiet and clever Little Duck, and friendly and gentle Porcupine. They use books in a whole new wa

After being cast as the Ninja Master in his school's Halloween play, a boy decides it is time to catch the monster in his closet.

Chinese-speaking popular cultures have never been so queer in this digital, globalist age. The title of this pioneering volume, Boys’ Love, Cosplay, and Androgynous Idols: Queer Fan Cultures in Mainla

Jigsaw Jones is back and better than ever in this brand-new chapter book mystery. Are aliens coming to Earth? Jigsaw and friends have a clue, but is there really life in outer space?

When it comes to opposites, it’s all a matter of perspective! Lively text and fun retro art engage kids in the finer points of a favourite concept.Get a whole new perspective on opposites in this styl

In the nine original essays collected in this volume, cultural historians,literary scholars, an art historian, and a historical musicologist set out to recover the sights, sounds, and smells of the So

Hong Kong has remained a wealthy financial hub but its income inequality is greater than that in any developed economy. The growing unequal income distribution and poverty in Hong Kong have aroused pu

The Book of Mistakes 是一本關於「錯誤」的美麗繪本。眼睛畫歪了？原來能變成另一種神情；墨漬弄髒了畫紙？竟變成飄浮葉片。這本繪本以輕巧文字與詩意畫面，邀請讀者一同走進創作的過程，也看見容許犯錯、保留空白的力量。ZoommeetsBeautiful Oops!in this memorable picture book debut about the creative process, and the way in which "mistakes" can blossom into inspirationOne eye was bigger than the other. That was a mistake.The weird cat-cow-frog thing? Well, it made an excellent bush.And the inky smudges . . . they look as though they were always meant to be leaves floating gently across the sky.As one artist incorporates accidental splotches, spots, and misshapen things into her art, she transforms her piece in quirky and unexpected ways, taking readers on a journey through her process. Told in minimal, playful text, this story shows readers that even the biggest “mistakes” can be the source of the brightest ideas—and that, at the end of the day, we are all works in progress, too.Fans of Peter Reynolds’sIshand Patrick McDonnell’sA Perfectly Messed-Up Storywill love the funny, poignant, comple

The wonder of being a dad is on display in this touching tribute to fathers. After all, the connection between a father and child yields a lifetime of learning and love. In You and Me, Me and You, tha

'stunning...succeeds in exploring complex topics in an exciting and visually accessible way' Born to Engineer 'smart writing and wonderful illustrations' How it Works Plunge into the world of science

In this spare, funny picture book about diversity and friendship, a carrot in a crowd of peas just doesn’t fit in.

On its first publication The Picture of Dorian Gray was regarded as dangerously modern in its depiction of fin-de-siècle decadence. In this updated version of the Faust story, the tempter is Lord Henr

Lovingly re-imagined illustrations highlight the timeless relevance and artistry of the legendary Brothers Grimm in this revised edition of Gestalten's beloved bestseller. Children delight in fantasy

In March 2017, the producers of ‘Godzilla’ transport audiences to the birthplace of one of the most powerful monster myths of all in KONG: SKULL ISLAND, from Warner Bros. Pictures and Legendary Pictur

In 1959 the Boston Red Sox was the last team in the Major Leagues to integrate. But when they call Elijah “Pumpsie” Green up from the minors, Bernard is overjoyed to see a black player on his beloved

In the tradition of Uni the Unicorn and Gaston, this heartwarming and adorable debut picture book tells the story of a young unicorn who was born under the sea to a family of narwhals.Growing up in th

Revisit one of the most beloved books in Laura Ingalls Wilder’s classic Little House series with this gorgeous hardcover, unjacketed edition of Little House in the Big Woods, featuring a special forew

To young James Herriot, fresh out of veterinary college, Yorkshire appears to offer an idyllic pocket of rural life in a rapidly changing world. But even life in the sleepy village of Darrowby has its

In 2016, the Hong Kong Designers Association (HKDA) enters its 45th year. Coincidentally, this will also be the 40th anniversary of the Global Design Awards (GDA). In celebration of these prestigious institutions, the 'Design NextGen Awards' and 'Best Design Teacher' awards have been established to acknowledge the importance of design education in the academic world. In addition to this 2016 will be the year that HKDA launches the 'Lifetime Honorary Award': an accolade dedicated to Dr Kan Tai Keung, who has contributed to the design industry for almost 50 years. With these awards, HKDA not only aims to further promote the field of design but to provide fertile soil for networking, allowing like-minded designers to connect and compete.HKDA Global Design Awards 2016 Annual Book 6500°K covers over 200 awarded works in 4 main categories - Digital, Graphics, Products (incl. Fashion), and Spatial & Environmental - with a further total of 41 related sub-categories. The book presents each

Throughout history, there has been an intrinsic need for humans to detect deception in other humans. Developed in 1923, the polygraph machine was a tool designed to do just this. To date, there have b

Two, four, six. Look at all the bricks!Grab a hard hat and all your tools, and get ready for a construction adventure in counting! This clever, rhyming picture book leads readers through a day in the

Infiltrate. Befriend. Sabotage.World War II is raging. Michael O'Shaunessey, originally from Ireland, now lives in Nazi Germany with his parents. Like the other boys in his school, Michael is a member

The Nativity is brought to life by master pop-up artist Robert Sabuda in six gorgeously imagined 3-D scenes, making this a Christmas gift book to treasure. Long ago, in a stable in Bethlehem, a baby w

在全球化已成日常的工作環境中，管理者必須具備跨文化理解與行動能力。本書第三版以「所有管理者都是全球管理者」為前提，重新梳理跨文化管理的理論與實踐。作者不僅介紹主要文化模型，也深入探討領導、溝通與倫理在不同文化脈絡中的差異與調適方式。更新後的內容更貼近現實職場，透過真實案例與具體策略，協助讀者面對國際指派、跨國團隊與多元勞動力的挑戰。語言清楚、結構明確，是學生建立基礎視野、也是專業人士精進能力的重要讀本。The third edition of this popular textbook has been thoroughly expanded and updated throughout to explore the latest approaches to cross-cultural management, presenting strategies and tactics for managing international assignments and global teams. With a clear emphasis on learning and development, this new edition introduces a global management model, along with enhanced 'Applications' and 'Manager's Notebooks', to encourage students to acquire skills in multicultural competence that will be highly valued by their future employers. These skills have never been more important, in a world where, increasingly, all managers are global managers and where management practices and processes can differ significantly across national and regional boundaries. This textbook is suitable for student

In the new book in Tedd Arnold's New York Times bestselling Fly Guy series, it's Christmazzz Eve and Fly Guy doesn't have a present to give his best friend, Buzz. But when he goes out to look for one,

A follow-up to the best-selling The Storm Whale, winner of the 2014 inaugural Oscar's First Book Prize in association with the Evening Standard. It’s winter time and Noi’s island is covered in a blank

The Later Tang was the first of several ephemeral states created by the Shatuo Turks in tenth-century China and Li Cunxu, a martial genius, was its founder. In fifteen years, he turned a small satrapy

A man named Rene floats through the world of his dreams and imagination, fulfilling his desire to become a painter—of apples and hats, apple hats, apple-these and apple-thats. In his paintings, leaves are lips, baguettes are noses, the right side is never up, and the upside is never down. Award-winning author Klaas Verplancke mashes everyday objects and words together in ways that are guaranteed to make kids laugh and think. Rene Magritte (Belgian, 1898–1967), one of the world’s most beloved artists, created whimsical, subversive paintings that helped launch the popularity of surrealism. His works combined words and images in novel, thought-provoking ways, and used humor and ordinary subjects to inspire viewers to question the world around them.

In 1960, Joy Adamson first introduced to the world the story of her life alongside Elsa - the lioness she had rescued as an orphaned cub and raised to adulthood at her home in Kenya. But, as Elsa had

A novel of social and moral themes, Hard Times is the archetypal Dickens novel, filled with family difficulties, estrangement, rotten values and unhappiness. Published in 1854, it is set in the imagin

In this special collector's edition, discover Patrick Ness's original prize-winning illustrated novel and the remarkable story behind the book and film. In exclusive essays and interviews, read how Pa

Set in the South of France in the decade after the First World War, Tender is the Night explores the new world of moneyed leisure found by the first generation of idle-rich Americans to take refuge in

Challenges young readers to find named objects in busy fold-out scenes set in the city, the country, at the sea, in the mountains, and in the air.