Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

The year is 2054, and life has been reduced to a data feed. The fusing of virtual reality and cybernetics has ushered in the era of the surrogate, a new technology that lets users interact with the wo

The real story of Little Red Riding Hood – told by the Wolf himself!Recounted in the confidential, conversational voice of a New York wheeler-dealer, this funny version of the Grimm Brothers' Little R

GAME OF THRONES: A NEW ORIGINAL SERIES, NOW ON HBO.Few books have captivated the imagination and won the devotion and praise of readers and critics everywhere as has George R. R. Martin’s monumental e

The third edition of this highly regarded series focuses on building confidence in using language needed in everyday settings.

The Lottery, one of the most terrifying stories written in this century, created a sensation when it was first published in The New Yorker. "Power and haunting," and "nights of unrest" were typical r

IT IS THE summer of 1938 when young Paul Moreaux discovers he can “fade.” First bewildered, then thrilled with the power of invisibility, Paul experiments. But his “gift” soon shows him shocking secre

Beginning readers are introduced to the detective mystery genre in these chapter books. Perfect for the Common Core, kids can problem-solve with Nate, using logical thinking to solve mysteries! Nate t

In a green jungle lived a little brown monkey. Early one morning, the little brown monkey sat in the tallest green tree wearing striped socks and shiny black shes.......

The Property market has always been a major driving force behind Hong Kong's economy. By providing a quality living and working environment, property development plays a significant role for Hong Kong

Join Bear as he tries out different forms of transport and has an adventure with each one. Rhyme and repetition support the learning layers of travel and transportation, as Bear travels in a raft, a r

THE BOOK BEHIND THE SECOND SEASON OF GAME OF THRONES, AN ORIGINAL SERIES NOW ON HBO.In this eagerly awaited sequel to A Game of Thrones, George R. R. Martin has created a work of unsurp

In this title, a renowned sports psychologist shows business leaders how to play to win - using the proven secrets of professional athletes. Business, like sports, is all about performance. Performanc

The exciting pieces in these collections are designed to entertain, reinforce and enhance the important music and technical skills being studied during the early levels. Students will develop their ow

Answer keyIntermediate LevelIncludes the answers for the task-based activities in this intermediate communication development program

Who are the men committing the rising number of serial homicides in the U.S. -- and why do they kill? The increase in these violent crimes over the past decade has created an urgent need for more and better information about these men: their crime scene patterns, violent acts, and above all, their motivations for committing these shocking and repetitive murders.This authoritative book represents the data, findings, and implications of a long-term F.B.I.-sponsored study of serial sex killers. Specially trained F.B.I. agents examined thirty-six convicted, incarcerated sexual murderers to build a valuable new bank of information which reveals the world of the serial sexual killer in both quantitative and qualitative detail. Data was obtained from official psychiatric and criminal records, court transcripts, and prison reports, as well as from extensive interviews with the offenders themselves.Featured in this book is detailed information on the F.B.I.'s recently developed Violent Criminal

New York City, 1972—A dabbler in mathematics and chess, Catherine Velis is also a computer expert for a Big Eight accounting firm. Before heading off to a new assignment in Algeria, Cat has her palm r

After Casey Happleton tells him that if he kisses his elbow he will turn into a girl, nine-year-old Marvin experiments and finds himself very confused about his identity.

Describes the racial prejudice experienced by Jackie Robinson when he joined the Brooklyn Dodgers and became the first black player in Major League baseball and depicts the acceptance and support he r

ntroduction and Notes by Dr Jeff Wallace, University of Glamorgan.Lawrence's finest, most mature novel initially met with disgust and incomprehension. In the love affairs of two sisters, Ursula with R

In Sharing the Dance, Cynthia Novack considers the development of contact improvisation within its web of historical, social, and cultural contexts. This book exam

During the eighteenth century, China's new Manchu rulers consolidated their control of the largest empire China had ever known. In this book Susan Naquin and Evelyn S. Rawski draw on the most recent r

The Mind of a Mnemonist is a rare phenomenon—a scientific study that transcends its data and, in the manner of the best fictional literature, fashions a portrait of an unforgettable human being.

Describes Dostoevsky's experiences in a prison camp in Siberia, examines the influence of Russian intellectual life on him, and discusses his early writings

INCLUDES:‧Four modules‧Five lessons and a revision section in each module‧Lively dialogues‧Motivating and contemporary topics with multicultural and cross-curricular information‧Systematic development

INCLUDES:‧Four modules‧Five lessons and a revision section in each module‧Lively dialogues‧Motivating and contemporary topics with multicultural and cross-curricular information‧Systematic development

Beep! Beep! Sheep in a jeep on a hill that’s steep. Sheep in a Jeep is well loved by the preschool and early-reader sets for its slapstick story of five sheep (in a jeep) and silly sound effects—espec

Beep! Beep! Sheep in a jeep on a hill that’s steep. Sheep in a Jeep is well loved by the preschool and early-reader sets for its slapstick story of five sheep (in a jeep) and silly sound effects—espec

Ideal for home learning, this set of 30 Early Readers is the perfect way to help your child learn to love reading. Short chapters and colour illustrations on every page help build children's confidence in reading aloud, bridging the gap from picture books to independent reading. From animal antics to familiar first experiences, there's something for everyone in this super stories.本書包含以下30本讀本Shumba's Big AdventureMercy and the HippoAnthony ant saves the dayA Friend For ChristmasHorrid Henry's StinkbombHorrid Henry's HolidayDon't Be Horrid,Henry!The Haunted House of Buffin StreetRampage in Prince's GardenJogger's Big AdventureCafe at the edge of the moonThe ant's pantsThe Boy Who Made Things UpPoppy the Pirate Dog's New ShipmatePoppy the Pirate DogJenny the Ponny's Big DayMicky's Magic PencilBlood And Guts And Rats Tail PizzaGrandad's MedalElsie and the Magic bisouir TirAlbert and the Garden of DoomMr Monkey Plays FootballsMr Monkey and the Magic TricksMr Monkey and the Fairy Tea PartyT

Play cubby with Bluey and Bingo in this board book with flaps.Bluey and Bingo are building a cubby for their toy, Kimjim. It includes an art room, a library and even an alpaca farm. Soon it’s so big, it’s easy to get lost in! What will Bluey and Bingo do when Kimjim goes missing? Lift the flaps in this board book to help find Kimjim!“It’s too many rooms!”Join Bluey and Bingo in this colourful board book with flaps and get lost in the cubby!Don’t miss these other awesome Bluey books:Bluey: GrandadBluey: Hide and SeekBluey: The WeekendBluey is an Emmy award-winning Australian children's television programme following the adventures of a loveable six-year-old Blue Heeler Puppy, Bluey and her family. It’s currently showing on Disney+, BBC iPlayer and CBeebies in the UK. Bluey enjoys exploring the world and using her imagination to turn everyday life into an amazing adventure. Join Bluey in this fun collection of story, activity and novelty books that celebrate play.

2025’s INSTANT No.1 SUNDAY TIMES best-seller from the author of YELLOWFACEPrepare for one hell of a journey…'A big, bold fantasy romp' GUARDIAN'R.F. Kuang is making magic' ELLE'[A] truly original and spellbinding hero's-journey story' VOGUE'I devoured it' REDOne of the BBC's 25 best books of 2025Katabasis, noun, Ancient Greek. The story of a hero's descent to the underworld.Grad student Alice Law has only ever had one goal: to become the brightest mind in the field of analytic magick.But the only person who can make her dream come true is dead and – inconveniently – in Hell. And Alice, along with her biggest rival Peter Murdoch, is going after him.But Hell is not as the philosophers claim, its rules are upside-down, and if she’s going to get out of there alive, she and Peter will have to work together.That’s if they can agree on anything.Will they triumph, or kill each other trying?2025’s most unexpected love story is going to be hell in the new No.1 Sunday Times bestselling novel by R

自然發音拼讀系列Phonics Step-By-Step 6：R-Controlled Vowels 《Phonics Step-By-Step 6: R-Controlled Vowels》為自然發音拼讀系列第六冊。此冊的 R-Controlled Vowels (R 控制的母音) 是以受 R 控制的母音為主軸，當母音 a、e、i、o、u後面接上子音 r 時，子音 r 會影響母音的發音，如： ar、er、ir、or、ur 等音組。這些音組也會有長音〔ɝ〕以及短音〔ɚ〕的不同發音，透過反覆的音組練習，學習者可以快速領略自然發音讓你輕鬆說英文的樂趣。 自然發音拼讀系列Phonics Step-By-Step 7：Gliding Blends and DIgraphs 《Phonics Step-By-Step》自然發音拼讀系列第七冊 Blends and Digraphs以混合及複合子音為主軸。混合子音包括 l、r、s 的雙子音混搭音組 (l-blends、r-blends、s-blends) 如 bl, br, sw 等，以及加入子音的混搭音組如 shr、str、spl、tw 等，都須拼讀及發出每個子音的聲音。而複合子音的音組如 ch、sh、th、ph、wh、ng、nk 等，都只能發出一個聲音。特定複合子音組合，還會產生特殊讀音。透過本書強化學習者自然發音能力，輕鬆說英文。 自然發音拼讀系列Phonics Step-By-Step 8：Gliding Blends and DIgraphs 《Phonics Step-By-Step》自然發音拼讀系列第八冊Special Sounds and Syllables，以特殊發音、音節、尾音、縮寫為主軸，包括認識 y、c、g 等子音的特殊發音；dge、gh、gn、kn、mb、tch、wr 等音組則會省略部分子音發音；還有常見的尾音 ed、s、es、ing；以及常用的英文縮寫。從基本發音，進一步到詞句、文章閱讀，幫助學習者有效練習自然發音。 英語進階學套組 自然發音法是從基礎的26個字母到特殊發音，一步一步的循序漸進讓你練習英語口說。 本套為自然發音法的進階內容，讓你輕鬆學習英文，有效練習發音。 【Phonics Step-By-Step】自然發音拼讀系列 Phonics Step-By-Step系列專為英文初學者打造，以英

如果有一天變成熊，你會做什麼？在本書中，「我」一早醒來，吃早餐、騎摩托車，還順手拯救被熱氣球帶走的好朋友——這些都是再正常不過的「熊日常」。當然，不可能站在全班面前做一份無聊又詳盡的熊類報告吧？Corey R. Tabor 以第一人稱視角巧妙鋪陳，讓讀者彷彿成了那隻熊，畫面邊緣還能看見熊的手腳晃動，幽默感十足。故事在出其不意的轉折中揭露真正的說話者，也溫柔回應孩子對上台報告的緊張。曾獲 Caldecott Honor 與三座 Geisel Award 的作者，再次帶來兼具創意與笑點的圖畫書。Assignment: Imagine yourself as a bear for the day. What would you do? Caldecott Honor and three-time Geisel Award–winning author and illustrator Corey R. Tabor offers an inspiring—and surprising—answer in this funny picture book for fans of Mo Willems, David Shannon, and Peter Brown.If you were a bear for a day, what would you do? Probably wake up, eat breakfast, go for a motorcycle ride, and rescue your best friend from a rogue hot air balloon. . . . You know, normal bear stuff!You certainly wouldn’t stand in front of the whole class and give a boring, detailed, and informational report about bears.Dynamically illustrated from the bear’s perspective, the Caldecott Honor and three-time Geisel Award–winning Corey R. Tabor delivers an innovati

Move the slider mechanism to answer funny questions about baby farm animals and lift five flaps to find hidden creatures! Explore farm life in this interactive and playful board book, which places the child at the centre of the action. Each spread is packed with fun and includes an engaging question about the scene. Decide and slide to choose your answer! Inside you’ll discover: Six multiple choice questions explore different farm scenes.Vibrant, bold and funny illustrations from Susie Hammer will keep little ones entertained and engaged. A multi-sensory reading experience, with a slider and flaps to lift. Spot the Quizzy Bean characters on each spread and lift the flaps to find out who’s hiding. Encourages active engagement and interaction, and helps children to express their knowledge and preferences. Each title in the series explores key Early Years concepts across the questions, for example: shape, colour or size. From Rebecca Atkinson – best known for pre-school series Mixmups, wh

Move the slider mechanism to answer funny questions about the home and lift five flaps to find hidden creatures! It's bedtime in this interactive and playful board book, which places the child at the centre of the action. Each spread is packed with fun and includes an engaging question about the scene. Decide and slide to choose your answer! Inside you’ll discover: Six multiple choice questions explore different rooms in a house.Vibrant, bold and funny illustrations from Susie Hammer will keep little ones entertained and engaged. A multi-sensory reading experience, with a slider and flaps to lift. Spot the Quizzy Bean characters on each spread and lift the flaps to find out who’s hiding. Encourages active engagement and interaction, and helps children to express their knowledge and preferences. Each title in the series explores key Early Years concepts across the questions, for example: shape, colour or size. From Rebecca Atkinson – best known for pre-school series Mixmups, which airs

Meet Izzy the Inventor in a laugh-out-loud series that brings together science, magic and a very lovable unicorn. Packed full of illustrations and easy-to-read text, this series is perfect for beginner readers and fans of Isadora Moon and The Naughtiest Unicorn.It's time for the school cooking competition and Izzy and her sister, Bella, are having an argument about the best way to build a cake tower, when Henry the Unicorn arrives with BREAKING NEWS: the TOP FIVE FAIRYTALE PRINCESSES have been kidnapped. Izzy and Henry must use their science skills to track down the princesses in Fairytale Land. Along the way, Izzy learns the secret to an excellent cake tower and, more importantly still, the power of sisterhood.Every book contains ideas for science experiments and a QR code with links for more to try at home.Collect all the books in the series!Izzy the Inventor and the Curse of DoomIzzy the Inventor and the Time Travelling GnomeIzzy the Inventor and the Teeny-Tiny OgresIzzy the Invento

Mirabelle 和家人到海邊度假，但大家規定整個假期都不能使用魔法。對調皮的 Mirabelle 來說，這幾乎是不可能的事。她忍不住偷偷施了一點魔法，想創造一個神奇的小生物，卻意外變出一群可愛又麻煩的小龍寶寶。於是，一場充滿混亂與笑聲的魔法假期冒險就此展開。Mirabelle and her family are on holiday, staying in a lovely cottage by the sea. There's just one problem-they're not meant to be using magic.Can Mirabelle manage a whole week without any magical mischief? Of course not! But perhaps she can use a teeny bit of magic to create a magical creature? Just for one night . . .Half fairy, half witch, totally naughty!Mirabelle and her family are on holiday, staying in a lovely cottage by the sea. There's just one problem-they're not meant to be using magic.Can Mirabelle manage a whole week without any magical mischief? Of course not! But perhaps she can use a teeny bit of magic to create a magical creature? Just for one night . . .From the Mirabelle series:• Mirabelle Gets Up to Mischief (ISBN: 9780192776495)• Mirabelle Breaks the Rules (ISBN: 9780192777546)• Mirabelle Has a Bad Day (ISBN: 9780192777553)• Mirabelle I

An jam-packed Bluey birthday sticker activity book!HIP, HIP, HOORAY! It's time for birthday celebrations!Play pass the parcel, decorate a duck cake and make bracelets with Bluey and Bingo in this birthday sticker activity book! It's jam-packed with activities including spot the difference, dot to dot and lots of colouring in to keep the biggest Bluey fans entertained. With over 100 stickers included, this activity book is the perfect birthday gift!Happy Birthday!Don’t miss these other awesome Bluey books:Bluey: Bluey and Bingo’s Fancy Restaurant CookbookBluey: Family and Friends Colouring in Sticker BookBluey: How to DrawBluey is an Emmy award-winning Australian children's television programme following the adventures of a loveable six-year-old Blue Heeler Puppy, Bluey and her family. It’s currently showing on Disney+, BBC iPlayer and CBeebies in the UK. Bluey enjoys exploring the world and using her imagination to turn everyday life into an amazing adventure. Join Bluey in this fun co

本書以R語言中的ggplot2包為核心，結合多種常用擴展包，系統講解科研圖表的構建邏輯與實現方法。內容涵蓋軟件環境配置、數據導入與整理、幾何對象、美學映射、比例尺、坐標系以及主題設置等關鍵環節，全面覆蓋科研可視化的核心流程。書中案例精選自Nature、Nature Communications、Nature Microbiology等國際期刊，基於其公開發表的真實數據進行改編，深入講解柱狀圖、散點圖、箱線圖、熱圖、Circos圖、桑基圖與網絡圖等多種常用科研圖形的繪製方法，幫助讀者在真實的科研語境中掌握高質量圖表的構建能力與可視化思維。

Accelerate your toddler's education in first words and shapes using this engaging board book designed by a professional artist and licensed speech therapist Scribble Scrabble takes your young child on an adventure as they learn new words and shapes through life-like paintings, bright colors, and an animal friend who guides them along the way. Written by licensed speech therapist Tabitha Paige, Scribble Scrabble features strategically chosen first words that include a child's earliest developing sounds, such as m, b, p, t, etc. With beautiful hand-painted art from Tabitha, this is the perfect baby book for a baby shower gift! So join our little mouse friend on a creative adventure as he takes your child through this first words book in a fun and interactive way!

Join in this popular nursery rhyme as you slide and play with this interactive board book!Sing along with your baby as you help Little Bo Peep find her lost sheep with this sturdy book that encourages language development. Use the Stories Aloud QR code to listen to the song and join in the words as you pull the sliders and spin the wheel. The perfect first introduction to this classic nursery rhyme. Other titles in the series: Here We Go Round the Mulberry Bush, Five Little Speckled Frog, Polly Put the Kettle On, Old MacDonald Had a Farm and Twinkle, Twinkle, Little Star, plus many more.