Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Gorey has never been funnier or more “impossible to resist” (Boston Herald) than in this peculiar retelling of Charles Dickens’s A Christmas Carol.

More than three centuries after he created Them, the exquisite enigmatic paintings of Johannes Vermeer continue to intrigue. In this volume, twenty-three scholars, conservators, and scientists investi

This fun book in the shape of a fire engine has four wheels so little drivers can race them anywhere. The big, tough wheels actually grip, and the beautiful, full color photographs inside are captione

Drawing on his years of experience in the metal trading community, the author examines the structure and workings of the London Metal Exchange (LME), risk identification and management; plus trading t

An analysis of 300-plus films with UFO and alien connections--from 1898's The Astronomer's Dream to 1997's Contact. The author analyzes the films in terms of their aesthetic merit, similarities with a

While searching for nuts in the forest, Hopper the hare meets a friendly squirrel and climbs up into his tree to spend time with him

Davy, formerly the youngest in the Rabbit family, is not happy about the arrival of a new baby, but he is surprised at what happens when he holds her for the first time

Essays in this volume focus on Singapore, Papua New Guinea, Taiwan, Japan, Thailand, and the People's Republic of China as sites rife with discursive complexity. From small to large, young to old, for

Qigong (CHEE-GUNG) has swept America as the newest approach to healing and was on the rise in China until the recent Falun gong crackdowns. This 2,500-year-old form of traditional Chinese medicine cla

Doing philosophy, according to Jerry Fodor, is like piloting: the trick is to find an object of known position and locate yourself with respect to it. In this book, Fodor constrasts his views about th

It is well known that the scope of individual rights has expanded dramatically in the United States over the last half-century. Less well known is that other countries have experienced "right

Fences is the first in a series of beautifully-produced books that feature authentic architectural patterns from the two previous centuries. Readers will find a treasury of period fence details-includ

The autobiography of Eugene Jolas, available for the first time nearly half a century after his death in 1952, is the story of a man who, as the editor of the expatriate American literary magazine tra

In this unique homage to an American icon, journalist and award-winning author Pete Hamill evokes the essence of Sinatra--examining his art and his legend from the inside, as only a friend of many yea

Presents information in concise and informative entries on many of the significant civilian and military persons, crucial diplomatic and political actions, as well as the essential military aspects of

Showcasing Frank Lloyd Wright's best work in interior design, this volume exemplifies the architect's principles of unity, simplicity and respect for nature. The rooms featured also represent a chrono

Alfa Romeo is synonymous with style and performance, and these qualities are epitomized in the 40 years of production that have gone into the marque's famous Spider series. From 1955's Guiletta Spider

This timely collection of essays - written by nine recognized forestry and environmental specialists - tells the story of the conservation, use, and changes in the Commonwealth's forests over time.The

Now associated with family health clubs, the YMCA's bland image is the result of relentless outreach and the studied avoidance of controversy. But, as John Gustav-Wrathall shows in his revealing socia

Bark, meow, whinny, or oink if you can talk to animals-just like Doctor Dolittle! Then join him and his pals-Tommy Stubbins, Jip the dog, and Polynesia parrot-as they journey to Spidermonkey Island in

These poems ? intrepid, obsessive, and erotic ? tell the story of a woman's attempt to overcome despair. Claudia Rankine, whose first collection was the prize-winning Nothing in Nature is Private, cre

Porter (business administration, Harvard Business School) collates 11 of his and coauthors' seminal articles on competitiveness in the private and public sectors from The Harvard Business Review and t

New York City and its famed Metropolitan Museum of Art provide the setting for a crazy collision of art and city life in this inventively illustrated picture book. It all starts with a little girl?s t

In their fortieth picture book, two Caldecott Medalists bring to vivid life the most famous verses from the biblical book of Ecclesiastes through imaginative paintings reflecting the world's various c

Follows the rise and fall of the personification of wealth (in the allegorical figure of the god Plautus) through the comedies of Aristophanes and Lucians and the tragedies of Shakespeare. Arguing tha

The Little Engine That Could, the star of the classic story by Watty Piper, has chug, chug, chugged her way into children's imaginations for nearly seventy years. Now this beloved character is a brightly colored windup train that zooms along four different grooved tracks in this new Motor Book?. The oversized board book retells the beloved story of the little blue engine that rescues a trainload of toys, bringing them over the mountain to the boys and girls on the other side. Each spread features a uniquely shaped track-the third spread unfolds to nearly two feet in length-along which the Little Engine windup toy travels as she makes her way over the mountain, uttering that famous refrain, "I think I can! I think I can! I think I can!" After play, the windup train can be popped back into the molded clamshell for easy storage. The bright, updated artwork and the inventive new format are sure to bring this timeless story to a whole new generation of fans.

Theories of Empire, 1450-1800 draws upon published and unpublished work by leading scholars in the history of European expansion and the history of political thought. It covers the whole span of imper

From a leading authority in the field, a groundbreaking look at harnessing the power of cross-functional global teams "World Class Teams is an invaluable resource for any company executive lo

A benchmark one-volume reference to today's radar remote sensing principles and applications This second volume in the Third Edition of the Manual of Remote Sensing offers a current and comprehensive

Remote Sensing for the Earth Sciences is a comprehensive, up-to-date resource for geologists, geophysicists, and all earth scientists. Produced in cooperation with the American Society for Photogramme

This text presents an advanced treatment of critical topics in monetary economics and the models economists use to investigate the interactions between real and monetary factors. It provides extensive

Includes 500 complex illustrations in full color. * Thorough cross referencing and Definition Entries (one paragraph dictionary articles). * Reference list contains not only traditional material, b

In writing this textbook the author's objective was to provide students with a non-trivial, reasonably priced introduction to astronomy. Starting with problems astronomers face on Earth connected with

Incentives are the most powerful tools executives can use to improve worker performance. This is particularly true in today's empowered workplace, where incentives can ensure that workers apply their

A totally new concept for clean surface processing of Si wafers is introduced in this book. Some fifty distinguished researchers and engineers from the leading Japanese semiconductor companies, such a

Making bread is fun--even more so when children participate. And when your guides are two of the luminaries in the world of food, you are sure to turn out splendid breads every time. Knead It, Punch I

"Mama Cat has three kittens, Fluffy, Skinny, and Boris. Whatever Mama Cat does, Fluffy and Skinny are right behind, climbing the wall, digging in the sand, chasing leaves. All Boris seems to do is nap

Argues that the lack of a national policy on children's rights in the United States is a major obstacle to ensuring children's entitlements to proper nurturing, protection, and self-determination are

This flexible textbook is both an introduction and a reader in metaphysics combining original discussion with selections from primary sources.

A practical, accessible guide to optimization problems with discrete or integer variablesInteger Programming stands out from other textbooks by explaining in clear and simple terms how to construct cu