Next-Generation MicroRNA Expression Profiling Technology

The rapid pace of microRNA (miRNA) research continues to drive the advances of techniques for miRNA expression profiling, and innovative technologies that are more sensitive, specific, quantitative, a

Tag-based approaches were originally designed to increase the throughput of capillary sequencing, where concatemers of short sequences were first used in expression profiling. New Next Generation Sequ

Photonics and electronics are endlessly converging into a single technology by exploiting the possibilities given by nanostructuring of materials and devices. It is expected that next-generation optoe

This volume includes comprehensive descriptions of miRNA biogenesis and their role in the development and progression of various human diseases. The first few chapters of MicroRNA Profiling: Methods a

This volume examines different approaches toward understanding the function of microRNA (miRNA) and the tools used to regulate microRNA expression in nervous systems. MicroRNA Technologies also explor

BabyLit® Storybooks give classics new life for the next generation of early readers.In Anne of Green Gables, preschoolers get to know the beloved redheaded orphan Anne Shirley, who is sent to live wit

BabyLit® Storybooks give classics new life for the next generation of early readers.In The Jungle Book, preschoolers can tag along on Mowgli’s thrilling adventure, meeting wolves, elephants, and even

BabyLit® Storybooks give classics new life for the next generation of early readers. Ahoy! Come sail the ocean blue with Captain Ahab, Ishmael, Queequeg, and the rest of the crew! The search is on for

Outperform the competition with Subir Chowdhury’s next-generation management system“Nobody knows quality like Subir Chowdhury, and The Power of LEO reveals the elegant new approach he has pioneered wi

From the world?s leading high-tech strategist comes the definitive road map to help established companies create next-generation growth. Geoffrey Moore?s now-classic Crossing the Chasm became a must

Get up close to nature with naturalist and TV presenter CHRIS PACKHAM CBE and encounter the amazing plant superheroes that will help us save the world. What links seaweed, forests and oranges? They are all SUPERHERO PLANTS! Explore the amazing plants that will help us save the world with CHRIS PACKHAM CBE, one of the UK’s leading naturalists and an award-winning conservationist. Discover some incredible plants and the amazing jobs they do – from supporting wildlife and providing food, materials for clothing or for building to inspiring inventions and new technology, and so much more! Packed with fun, facts and challenges – perfect for readers aged 6 to 9.Welcome to LITTLE EXPERTS – inspiring the next generation of experts! • Written by expert authors, famous for their passion and expertise • Must-read introductions to key non-fiction topics with colour illustrations throughout • Created to empower and inspire! Also available in the series: Superhero Animals by CHRIS PACKHAM CBE. How to

Next-generation sequencing technology allows rapid sequencing of a patient's DNA. This book introduces the technology and describes how it may be used in personalized medicine to diagnose diseases su

Microarray analysis is a highly efficient tool for assessing the expression of a large number of genes simultaneously, and offers a new means to classify cancer and other diseases. Gene expression profiling can also be used to predict clinical outcome and response to specific therapeutic agents. This survey spans recent applications of microarrays in clinical medicine, covering malignant disease including acute leukaemias, lymphoid malignancies and breast cancer, together with diabetes and heart disease. Investigators in oncology, pharmacology and related clinical sciences, as well as basic scientists, will value this review of a promising new diagnostic and prognostic technology.

Get inside the machinery of the modern world and understand the science that makes it all work. Have you ever been tempted to take the back off your TV? Have you wondered about what's going on beneath your feet on the street where you live? How Technology Works lifts the lid on the technology you use all the time but take for granted. It also takes you to places you'll never get the chance to see, such as the inside of a nuclear storage facility or the crew capsule on top of a moon rocket. The book takes you on a journey of discovery, starting with technology at work inside the human body before exploring cities and factories and then blasting off into space. Along the way, you'll lose yourself in super-detailed illustrations that reveal amazing hidden things and explain how they work. How Technology Works is an inspiring guide that makes technology fun, fascinating, and accessible for curious minds of all ages.

It's never too soon to share your favourite classics with the next generation... This edition of Alice in Wonderland has been adapted for younger readers and features:• Simplified text• A child-friendly layout, designed for young readers• Full-colour illustrations by award-winning artist Robert Ingpen. In Alice's quest, she meets a cast of unforgettable characters – the Mad Hatter and the March Hare, the sleepy Dormouse, the fearsome Queen of Hearts and, of course, the smiling Cheshire Cat.But where is the White Rabbit? And what is he late for? And how will she ever find her way home?A full-colour illustrated edition of one of the world's best loved stories. 'Ingpen's drawings are utterly compelling' – Michael Morpurgo

What Happens Next is a raw, realistic story told by an unnamed protagonist who feels different from everybody else, like she doesn’t quite fit in. Bullied by a girl at school, our narrator gives a ter

An amusing, original story with easy reading text, speech bubbles and delightful illustrations on every page.The eccentric Mr. Puff lives next door to Sam in a house full of interesting things - inclu

This volume focuses on the analysis of miRNA and its many components such as targets and expression profiling, regulation of gene expression, miRNA detection in biofluids, and its application in cance

Recent advances in genomics technology has dramatically reduced the cost of genome sequencing. Huge amounts of data is generated by next generation sequencing (NGS) technologies, posing substantial da

The book provides the most updated and comprehensive microRNA (miRNA) clinical evidence from worldwide renowned scientists. It is now known that miRNAs can suppress the expression of key genes involve

Next-generation DNA sequencing (NGS) technology has revolutionized biomedical research, making genome and RNA sequencing an affordable and frequently used tool for a wide variety of research applicati

Written by leading experts from industry and academia, this comprehensive resource addresses recent developments in next generation DNA sequencing technology and their impact on genome research, drug

A girl's community joins hands to fight intolerance and antisemitism in this richly illustrated picture book that sings with hope for young readers. Leila loves going to Hebrew school and hearing stories of mighty kings and quick-witted queens. Being Jewish is a part of her story, and learning Hebrew connects her to her ancestors. L'dor V'dor! From one generation to the next! But when Leila's synagogue gets vandalized, she isn't sure she wants to be Jewish. It makes her feel different. She doesn't want to stand out if it means people won't like her. Then Leila's classmates and community come together to repair the synagogue. This compassionate gesture makes Leila realize that everyone around her is different--and that's a beautiful thing. Lyrical text and gorgeous, textured collage art by award-winning illustrator Selina Alko make a powerful statement in this uplifting story based on an event from the author's childhood. Back matter, including a glossary and an author's note, provide a

This jam-packed collection of fun and simple science experiments for kids is perfect for the classroom or home. Stir up some sticky slime, build a solar system with rubber bands, power a speed boat using soap, and construct an erupting volcano, all with Home Activity Lab, which offers exciting experiments for budding scientists. Including a foreword by Professor Robert Winston, this stunning book includes 28 brilliant science projects using simple step-by-step instructions, everyday ingredients that can be found around the house, and amazing photography to guide you from start to finish. Each experiment describes the science behind the project, highlighting STEM facts with STEM icons pointing out the key science, technology, engineering, and math learning involved in each project. "Take it further" panels encourage young readers to experiment and take their projects to the next level, developing their independence, initiative, and creative thinking skills. Perfect for budding scientist

"It’s sensibly written and beautifully illustrated." – The Telegraph Hit the road with writer and broadcaster JAMES MAY to discover incredible human-powered vehicles – from bicycles and submarines to amphibious vehicles and even a helicopter. Yes, really! Packed with fun, facts and challenges – perfect for readers aged 6 to 9. Welcome to LITTLE EXPERTS – inspiring the next generation of experts! • Written by expert authors, famous for their passion and expertise • Must-read introductions to key non-fiction topics with vibrant, colour illustrations throughout • Created to empower and inspire! Also available in the series: How to Build a Home by GEORGE CLARKE, an architect, writer, lecturer and TV presenter.Why Money Matters by DEBORAH MEADEN, entrepreneur, Dragons' Den investor and host of the BBC Radio 5 Live’s The Big Green Money Show podcast. Why Politics Matters by ALASTAIR CAMPBELL, a writer, podcaster and strategist who is best known for his work as former PM Tony Blair’s spokespe

Winner of the Children's Literature Festivals Book Award for Non-fiction and the Teachers’ Award Inspired by the incredible human body? Take a tour with DR RONX – TV presenter on CBBC’s Operation Ouch! and an award-winning trans non-binary emergency doctor – to discover spongy brains, gooey guts and everything in between. Packed with fun, facts and challenges – perfect for readers aged 6 to 9. Welcome to LITTLE EXPERTS – inspiring the next generation of experts! • Written by expert authors, famous for their passion and expertise • Must-read introductions to key non-fiction topics with vibrant, colour illustrations throughout • Created to empower and inspire! Also available in the series: How to Save a Life by DR RONX.Why Money Matters by DEBORAH MEADEN, entrepreneur, Dragons' Den investor and host of the BBC Radio 5 Live’s The Big Green Money Show podcast. Marvellous Vehicles by JAMES MAY, a writer and broadcaster who is best known for co-presenting Top Gear and The Grand Tour. How Fam

Two legal systems founded on similar Enlightenment philosophical and political values use state coercion differently to regulate a liberty at the core of the Enlightenment: freedom of expression. This comparative study of France and the United States proposes a novel theory of how the limits of freedom of expression are informed by different revolutionary experiences and constitutional and political arrangements. Ioanna Tourkochoriti argues that the different ways freedom of expression is balanced against other values in France and the United States can be understood in reference to the role of the government and the understanding of republicanism and liberty. This understanding affects how jurists define the content and the limits of a liberty and strike a balance between liberties in conflict. Exploring both the legal traditions of the two countries, this study sheds new light on the broader historical, social and philosophical contexts in which jurists operate.

The 2014 International Conference on Industrial Engineering and Manufacturing Technology (ICIEMT 2014) was held July 10-11, 2014 in Shanghai, China. The objective of ICIEMT 2014 was to provide a platf

Next Generation Sequencing technology has been applied to clinical diagnoses in the past three to five years using various approaches, including target gene panels and whole exomes. The purpose of th

By offering readers a groundbreaking analysis of virtual computing technology and its effect on business processes, Denis Kudriashov and Kim Montes' book Mastering Next Generation IT is now the go-to

Next Generation Sequencing (NGS) is the latest high throughput technology to revolutionize genomic research. NGS generates massive genomic datasets that play a key role in the big data phenomenon that

????This volume provides an interdisciplinary perspective of applying Next Generation Sequencing (NGS) technology to cancer research. It aims to systematically introduce the concept of NGS, a variety

Agri-food bio-technology policy and regulation is transitioning from an early period focused on genetic engineering technologies to ‘next-generation’ rules and regulatory processes linked to challenge

"Brain-inspired information technology" is one of key concepts for the development of information technology in the next generation. Explosive progress of computer technology has been continuing based

The #1 New York Times bestselling series is back with a brand new tale! Discover what happens next in this thrilling addition to the Wings of Fire saga.One of the biggest secrets in the Wings of Fire saga will be revealed . . . .In the new and highly-anticipated sixteenth book in the #1 New York Times bestselling Wings of Fire series, beloved author Tui T. Sutherland will answer the question her fans have been asking her for years. Be the first to read this brand new story in the series that is devoured by dragon fans the world over. Where will the next adventure take us? You'll find out in Wings of Fire: The Hybrid Prince.

This new edition of the award-winningTheBrain Bookuses the latest findings from neuroscience research and brain-imaging technology to take you on a journey into the human brain.CGI artworks and MRI scans reveal the brain's anatomy in unprecedented detail. Step-by-step sequences unravel and simplify complex processes, such as how nerves transmit signals and how memories are laid down and recalled. The book answers fundamental and compelling questions about the brain, such as what it means to be conscious and what happens in the brain when we're asleep.Written by award-winning author Rita Carter, this is an accessible reference book to a fascinating part of the human body. Thanks to improvements in scanning technology, our understanding of the brain is changing fast. Now in its fourth edition, The Brain Book draws on the latest information to provide a fascinating guide to one of science's most exciting frontiers.

Look to the sky!High above the ground, generation after generation, Native workers called skywalkers have sculpted city skylines, balancing on narrow beams, facing down terrifying heights and heartbreaking loss. These skywalkers who dared to touch the heavens have built a legacy of landmarks all over the North American continent--and even today, there are Native Americans still climbing up among the clouds, brave enough to walk the sky.With impactful and illuminating prose, Patricia Morris Buckley (Mohawk) tells the soaring story of the remarkable skywalkers, whose bravery and tragedies are warmly captured in moving watercolors by award-winning artist E. B. Lewis (Lenni-Lenape).

Dream up anything you like, dear reader, and watch it come to life on the next page--just no tigers! This fun read-aloud about creativity and perspeverance will have your reader giggling and inspired, all while our hero learns that with a bit of practice, even the wildest challenges can be tamed. This book is MAGIC! Imagine anything you like, and the illustrator will draw it on the next page. There's only one rule: DON'T THINK OF TIGERS! Ready? Oh dear. You thought of tigers, didn't you? Please, think of anything else. A cow doing ballet? No problem! Just no tigers. Our illustrator really, really can't draw tigers... Or can he? As his hilariously silly and irresistibly charming drawings of tigers improve, Alex Latimer delivers a subtle but important message about practice, creativity, and embracing imperfection. A fun read-aloud that's sure to delight time and time again, this is the perfect book for kids who love to draw--and for those who don't (but might soon!).

The Art of Elemental showcases the art and making of the next animated film from Pixar Animation Studios.The Art of Elemental presents the story behind the newest film from Pixar Animation Studios. It highlights the stunning artwork from the film's creation—including character designs, storyboards, color scripts, and much more—and features exclusive interviews from the creative team along with behind-the-scenes details. The next in this fan-favorite, collectible series of Art of titles, this book is the perfect gift for aspiring artists, animators, aspiring film buffs, and fans alike.Copyright ©2023 Disney Enterprises, Inc. and Pixar. All rights reserved.EXCLUSIVE BEHIND-THE-SCENES DETAILS: Fans will want to delve into and explore this new Pixar Animation film through production art, stories, and making-of details exclusive to this book.PART OF THE FAN-FAVORITE SERIES: The collectible Art of series from Disney and Pixar are perfect for animation enthusiasts, filmmakers, students, and f

Geronimo is in for future shock as his house gets a major upgrade!Geronimo Stilton is so busy as the editor-in-chief of The Rodent’s Gazette, competing for scoops with rival Sally Ratmousen and her Daily Rat newspaper, and always being dragged into unexpected zany adventures, that he has neglected a bit of his housework. His nephew Benjamin suggests that Geronimo hire some help to clean up around his home. Enter: Professor Cheesewheel and his plan to fully automate Geronimo’s house with all the bells, whistles, and technology that money can buy. But will the technology become too much to handle? Geronimo may have to pick up the pace, and even a broom, to clean up this mess! Based on the hit animated series!