Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

From the international bestselling creator of Claude, comes a brand new hero - Mr Penguin, adventurer and penguin. Indiana Jones meets Hercule Poirot in this new Alex T. Smith series with plenty of sl

☆除了識字，我們給孩子比想像的多更多！☆語言、記憶、閱讀、數理思考、創造與解決問題等6大類，一次通通解決。本系列針對2-6歲學齡前的幼兒設計，整合式的教材編排、分齡的學習、針對不同腦部區域的開發，一次滿足爸媽為孩子尋找合適學習媒介的煩惱。「6歲 頭腦開發遊戲--動動手動動腦2 in 1」是一套深受眾多幼稚園肯定的全方位教材，針對6、7歲學齡前的幼兒設計，內容含括：一、認知訓練：形狀對應、認識錢幣、

Tempted by the promise of fame and fortune, the Singing Mermaid joins a circus. The crowds love her, but the poor mermaid is kept in a tank by the wicked circus owner Sam Sly, and she soon longs to re

When Crab finds a new shell, he doesn't want to share it with anyone - especially not a blobby purple anemone and a tickly bristleworm. But life in the rock pool proves tougher than Crab thinks and he

There used to be an empty chair at the back of my class, but now a new boy called Ahmet is sitting in it. He's eight years old (just like me), but he's very strange. He never talks and never smiles an

Ice Cream Cone Worm. Monkeyface Prickleback. Pink Fairy Armadillo. You're called WHAT?! Welcome to the Ministry of Silly Animal Names where all the creatures have one thing in common: they want to cha

A shy little ghost who’s new to the group has trouble fitting in — until his special talent comes to the fore.Boo is new. And even if the other kids are welcoming, it can be scary being ne

A warm, welcoming picture book that celebrates diversity and gives encouragement and support to all kids.Follow a group of children through a day in their school, where everyone is welcomed with open

Discover what energy is, where it comes from, and how we use it in this information-packed book full of amazing images, fun quizzes, and incredible facts.Did you know that a bolt of lightning produces

A strikingly original first novel, from the author of A Little Life. ‘The world Yanagihara conjures up, full of dark pockets of mystery, is magical.’ – The TimesIn 1950 Norton Perina, a young doctor, embarks on an expedition to a remote Micronesian island in search of a rumoured lost tribe. There he encounters a strange group of forest dwellers who appear to have attained a form of immortality that preserves the body but not the mind.Perina uncovers their secret and returns with it to America, where he soon finds great success. But his discovery has come at a terrible cost, not only for the islanders, but for Perina himself. Hanya Yanagihara's The People in the Trees marked the debut of a remarkable voice in American fiction.‘Impossible to resist’ – Daily MailPart of the Picador Collection, a new series showcasing the best of modern literature.

Say cheese! Thea’s adventures have great chuckles and colour pictures, and they’ll take you right around the globe. Just like her big brother Geronimo, Thea Stilton is a mouse with a nose for a good mystery. But unlike scaredy-mouse Geronimo, Thea loves adventures. Join this thrill-seeking rodent as she heads off all around the world, cracking cases wherever she finds them.#41: Mighty Mount Kilimanjaro (Geronimo Stilton)#42: The Peculiar Pumpkin Thief (Geronimo Stilton)#43: I'm Not a Supermouse! (Geronimo Stilton)#44: The Giant Diamond Robbery (Geronimo Stilton)#45: Save the White Whale! (Geronimo Stilton)#46: The Haunted Castle (Geronimo Stilton)#47: Run for the Hills, Geronimo! (Geronimo Stilton)#48: The Mystery in Venice (Geronimo Stilton)#49: The Way of the Samurai (Geronimo Stilton)#50: This Hotel Is Haunted! (Geronimo Stilton)

Uncover a magical world as you etch your own folk-art in these activity books that take you on a journey through nature. Birds, bees, and other enchanted creatures hide beneath panels of scratchable i

★ 英倫奇幻冒險《The Uncommoners》三部曲震撼完結★ 魔法城市 × 神祕交易市場 × 世界級奇幻冒險★ 從倫敦地下城市到紐約神祕市場，魔法世界全面擴張★ 《哈利波特》《善惡學院》讀者必讀的奇幻系列最終章艾薇、賽布與瓦利安展開第一次海外不凡者任務，前往隱藏在紐約地下的神祕交易市場Nubrook，尋找瓦利安失蹤多年的妹妹Rosie。然而黑暗勢力Dirge也在追尋她，同時盯上一件威力驚人的Great Uncommon Good魔法物品。當陰謀逐漸浮現，一場攸關整個不凡者世界命運的終極冒險即將展開。After the thrilling events which concluded The Smoking Hourglass, Ivy, Seb and Valian think they've vanquished their enemies, and those of Lundinor, forever. It turns out their adventure was only just beginning . . . Ivy and Seb can't wait to join Valian for their first ever overseas uncommon adventure - they're meeting in Nubrook, the completely astonishing and totally-different-to-Ludinor trading market hidden underneath New York. But there's no time to enjoy looking round all the incredible sights - they're on a mission to find Valian's long-lost sister, Rosie.But it seems they're not the only ones looking for her. Once again the Dirge rear their terrifying heads, and it appears they're after not only Rosie, but another enormously p

What do you want to eat today? There are so many treats you can eat in a week! These pages are packed with flaps to lift, tabs to pull and plenty of surprises.

Get ready for some spooky alphabet fun in this board book with lift-the-flap and die-cut trace elements! On each page, a new letter of the alphabet is introduced with a sturdy die-cut letter to trace

New in the New York Times and USA Today bestselling series comes a mermaid tale! Many claim to have caught a mermaid, but can YOU? How do you catch a mermaid? You must be very clever. With mirrors, cr

《English for Everyone》英語自學用書。套書分級落在多益考試500-900分之間，插圖輔助原意簡單不複雜的例句，更以顏色、方塊分解文法結構、時態變化，搭配母語者標準發音之音檔及多樣化練習題，突破牢記死背的學習法。Our Intermediate to Advanced Box Set is a great bundle of supportive reference guides and practice books to introduce English language rules, grammar, and vocabulary at an advanced level.Ideal for English test preparations or ESL lesson plans, the Course Books use visual teaching methods to introduce the English language, reinforced through a variety of exercises and examples when used alongside the bundled Practice Books.In Level 3, expand your English conversational topics by increasing the detail around your interests, life stories, and achievements, as well as being able to give instructions, advice, or solutions to problems. Continue to an advanced understanding in Level 4 and cover topics such as family life, careers and business, news and media, and even laws, rules, and regulations. Whether you are looking for ESL teaching resources, or a structured program for adu

Techies in training will go bezerk over this sticker activity book, packed with 1,000 robot-themed stickers and pages loaded with sticker prompts, coloring activities, counting, patterns, mazes, match

A 25th anniversary edition of the enchanting story of a widow who finds herself in possession of an extraordinary broom after a witch falls into her garden. Some of Minna Shaw's neighbors don

Now in paperback, the bestselling author of The Martian returns with an irresistible new science fiction thriller—a heist story set on the moon. Jazz Bashara is a criminal. Well, sort of. Life on Arte

Just in time for the 25th anniversary, relive the action of Tim Burton's The Nightmare Before Christmas with our best-selling Read-Along and Storybook and CD, featuring narration, character voices, a

1. 9780500651667 Are You Hungry? (趣味立體操作書)What do you want to eat today? There are so many treats you can eat in a week! These pages are packed with flaps to lift, tabs to pull and plenty of surprises

As a sequel to An Encyclopedia of Translation: Chinese-English English-Chinese, which was published in 1995, this volume, An Encyclopedia of Practical Translation and Interpreting, focuses on practica

Innovation is the process of value creation through use of relevant knowledge, capabilities and resources for conversion of ideas into new products, processes and practices, and improvements in existi

The fourth title in this popular picture book series sees Pussy cat exploring the sights and sounds of the Italian capital. From the Coliseum to the Sistine Chapel, all the major tourist attractions a

Mary Ann dreams of becoming an opera singer, and she's thrilled when the famous child prodigy Mozart performs in Chelsea. But suddenly Mary Ann is told that she must leave her Boarding School for Youn

Geronimo decides to buy his aunt's old farm where he used to spend the holidays. It's filled with memories from his childhood! There is a large oak tree in the yard that holds legendary secrets to unl

Ranger, the time-traveling golden retriever with search-and-rescue training, arrives in New Orleans as Hurricane Katrina approaches and residents start to evacuate the city. Ranger meets Clare Porter,

A special new edition in celebration of the 20th anniversary of the publication of Harry Potter and the Sorcerer's Stone, with a stunning new cover illustration by Caldecott Medalist Brian Selznick.Th

A special new edition in celebration of the 20th anniversary of the publication of Harry Potter and the Sorcerer's Stone, with a stunning new cover illustration by Caldecott Medalist Brian Selznick. H

A special new edition in celebration of the 20th anniversary of the publication of Harry Potter and the Sorcerer's Stone, with a stunning new cover illustration by Caldecott Medalist Brian Selznick.Th

A special new edition in celebration of the 20th anniversary of the publication of Harry Potter and the Sorcerer's Stone, with a stunning new cover illustration by Caldecott Medalist Brian Selznick. F

A special new edition in celebration of the 20th anniversary of the publication of Harry Potter and the Sorcerer's Stone, with a stunning new cover illustration by Caldecott Medalist Brian Selznick. "

★ 美國圖書館協會「最佳兒童圖像小說」得獎系列★ 《Dog Man》作者 Dav Pilkey 熱情推薦！★ 最適合國小讀者入門的校園圖像小說Mr. Wolf剛開始在Hazelwood小學任教，第一天就要面對一群個性鮮明的學生：新來的Margot、神祕的Sampson、認真的Aziza，以及總是睡不飽的Penny。當Penny突然不見時，全班一起展開尋找行動。本書以溫暖幽默的圖像故事描寫教室日常，是一部貼近孩子生活的校園圖像小說。American Library Association Best Graphic Novel for Children, 2021 and 2022 Chicago Public Library Best of the Best Books ListMr. Wolf has just started teaching at Hazelwood Elementary. He wants the first day of school to go well, but he's got his hands full with his new class. Some of his students include: Margot, who is new in town and is trying to make friends. Sampson, who brought something special to school for show-and-tell. Aziza, who just wants everyone to be quiet and do their work. And Penny, who is VERY sleepy because she has a new baby brother at home, goes missing! This delightful new series captures the everyday -- and unexpected -- ups and downs of a fourth-grade classroom.

A special new edition in celebration of the 20th anniversary of the publication of Harry Potter and the Sorcerer's Stone, with a stunning new cover illustration by Caldecott Medalist Brian Selznick. T

A special new edition in celebration of the 20th anniversary of the publication of Harry Potter and the Sorcerer's Stone, with a stunning new cover illustration by Caldecott Medalist Brian Selznick. W

What if you woke up one morning and you had sprouted a tail overnight? What If You Had An Animal Tail? -- the next imaginative book in the What If You Had series -- explores what would happen if you l

This junior novelization retells storylines from many episodes of the hit new show Mysticons!In Drake City, where magic and technology meet, four girls are brought together by an ancient prophecy. Pri

In this companion to the Caldecott Honor and Coretta Scott King Award–winning Trombone Shorty, join a scrappy young musician named Shorty on a tour of his beloved New Orleans. After letting his band d

Lone Survivor meets Marley & Me in this “inspiring and very moving” (Bear Grylls, host of the hit TV show Man vs. Wild) memoir of an extraordinary service dog whose enduring love brought a