Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

This exciting new strand of Charlie and Lola activity books provides fun and accessiblity across key early years learning topics. From Children's Laureate Lauren Child.

The rules for finding professional work once seemed clear and unwavering: capture career highlights in a resume, practice answers to standard interview questions, and do lots of face-to-face networking. Cracking the New Job Market shows how these rules have changed and delivers new job-hunting strategies that actually work. The key, rather than to emphasize past accomplishments, is to sell your self on the value you can create for an employer. This new approach to getting hired requires new skills. Author R. Willam Holland, a human resources insider, shows job seekers how to: * Gather information on what a prospective employer finds important * Emphasize those skills, accom plish ments, and qualities in tailored resumes and interview answers * Identify the intersection between personal talents and what the marketplace needs * Unlock the networking power of social media * Negotiate the best possible offer Enlightening and practical, this myth-busting book delivers seven powerful rules f

A practical, dip-in guide, packed with over 100 outdoor activities for children.In an era when the iPad is often more appealing than the park, it can be difficult to encourage kids to get off the couch and spend time outside. In this inspirational book, with ideas for children of all ages, there are over 100 imaginative ways for children to keep busy and have fun outdoors. They can enjoy outdoor crafts such as making leaf art bunting, a dream catcher, or their own toy raft, or get physical and burn off some energy with beach hopscotch, animal tracking, and developing their hunting and gathering skills. Or perhaps they would like to relax and enjoy some star-gazing or pond-dipping instead. There are fun activities to help kids get up close and personal with nature by making a wormery and a bug attractor, doing some investigative ant experiments, and putting on their own gastropod race! The book includes handy reference pics to help children identify plants, flowers, and wildlife, so as

Updated and revised to meet all current standardsThis is a concise step-by-step guide for novice nurse educators on the development of new programs and curricula or the revision of existing ones that

The Evan-Moor Smart Start STEM Grade 1 Activity Book introduces scientific concepts to first graders using a mixture of hands-on activities, stories and problem solving tasks that are sure to keep kids entertained while theyre gaining invaluable skills. When working on physical science concepts, gr. 1 students will focus on the differences between solids, liquids and gases. The life science sections discuss the things animals eat and how they take care of their babies, all in language that grade one kids can comprehend. And, in the earth science lessons, well introduce concepts about the moon, bodies of water and weather.

The Evan-Moor Smart Start STEM Grade 1 Activity Book introduces scientific concepts to first graders using a mixture of hands-on activities, stories and problem solving tasks that are sure to keep kid

After a few early glitches in their relationship, Sammy and his 'bro-bot' E are now best friends. In fact, E is such a valued member of the family that the other electronic members of the House of Rob

黑暗勢力正籠罩大地 Perodia，禿鷲 Thorn 帶領間諜大軍，企圖以黑魔法毀滅世界。小貓頭鷹 Tag 雖渴望成為勇敢的戰士，卻還太稚嫩。與他的好友松鼠 Skyla，以及最後一隻火鷹攜手，他們踏上尋找魔法石的旅程。故事節奏明快，人物討喜，是孩子接觸奇幻與任務冒險的絕佳入門。Pick a book. Grow a Reader!This series is part of Scholastic's early chapter book line Branches, aimed at newly independent readers. With easy-to-read text, high-interest content, fast-paced plots, and illustrations on every page, these books will boost reading confidence and stamina. Branches books help readers grow!A terrible darkness is spreading across Perodia. Thorn, a powerful vulture, is using dark magic (and his dark army of spies!) to destroy the magical land. A young owl named Tag may be the only one who can save it! Tag dreams of one day becoming a brave warrior, but he is small... In this first book, Tag and his best friend -- a squirrel named Skyla -- meet the last firehawk. Together, the three friends learn about a magical stone. Could this stone be powerful enough to defeat Thorn? This action-packed series makes a great introduction t

The wacky robots from the award-winning StoryBots apps, videos, and Netflix show now star in their own early readers. This one is about everyone’s favorite dinosaur!Fans of the StoryBots will recogniz

★ 前華爾街量化分析師揭露：演算法如何操控你的未來★ 大數據黑暗面全面曝光：看不見的歧視與不公平我們以為世界正變得更公平——由機器取代人類做決策，似乎能消除偏見。但真相，可能正好相反。在這個「演算法主宰」的時代，你能否錄取學校、拿到工作、申請貸款，甚至保險費率高低，都悄悄被一套看不見的數學模型決定。這些系統看似客觀，卻無法被檢驗，也無從質疑，一旦出錯，影響卻會層層放大。數學家暨資料科學家凱西．歐尼爾，以親身經驗揭開大數據的陰暗面：這些模型不只沒有消除不平等，反而強化既有的階級與歧視，讓弱勢更難翻身。本書如同一場警醒之旅，帶你看見科技背後不為人知的權力運作。NEW YORK TIMES BESTSELLER • A former Wall Street quant sounds the alarm on Big Data and the mathematical models that threaten to rip apart our social fabric—with a new afterword“A manual for the twenty-first-century citizen . . . relevant and urgent.”—Financial TimesNATIONAL BOOK AWARD LONGLIST • NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The New York Times Book Review • The Boston Globe • Wired • Fortune • Kirkus Reviews • The Guardian • Nature • On PointWe live in the age of the algorithm. Increasingly, the decisions that affect our lives—where we go to school, whether we can get a job or a loan, how much we pay for health insurance—are being made not by humans, but by machines. In theory, this should lead t

Open this book to see stylish, black and white illustrations… then brush water over them using the brush provided to see them change before your very eyes, as a rainbow of colors magically reveal them

Chosen as one of The New York Times Best Illustrated Children's Books 2016 Little Red Riding Hood meets a wolf on her way through the woods to visit her sick grandmother. The wolf is hungry, and Red R

From TV Star to the dorkiest princess around, life is anything but dull for Nikki Maxwell! This dork-tastic bind-up features TV STAR and ONCE UPON A DORK as Nikki goes from being the star of her own r

“A brisk historical tour of the marketing and selling of the small principality of Monaco and its famous city…A well-researched, dramatic rags-to-riches urban tale” (Kirkus Reviews) of Monte Carlo’s r

●一本學通！當代量化研究的主要統計方法學典範：結構方程模型（SEM）。●扎實的統計方法說明，並提供不同情境的實證分析範例。●圖片詳解操作流程，無痛學習地表最強統計軟體──Stata。●本書範例檔案建議使用Stata 13或更新版本執行。◎隨書附贈資料檔光碟 結構方程模型（structural equation modeling, SEM）是一種結合路徑分析（path analysis

Hooked on Phonics® Learn to Read Levels 5&6 Complete includes both 1st Grade levels in the complete 8-level Learn to Read series.- Level 1: Early Emergent Readers (Pre-K)- Leve

本書提供學生在研究實物上珍貴的紙引，包含分析資料與操作電腦套裝軟體。內容務實且希望能聚焦在研究分析者真正的需求上，故部分章節除了彙整實用基礎統計學外，也指導如何有效呈現數據。此書著重於協助您針對資料選擇適合的統計檢定方法，還要利用統計軟體進行分析，並將研究結果做最佳的解讀詮釋；軟體包括SPSS、Minitab、Excel和R，其中R軟體僅於此最新版中介紹。我們盡量以清楚易懂的文字介紹統計，而特殊專

Bringing together leading critics and literary scholars, A New Vocabulary for Global Modernism argues for new ways of understanding the nature and development of twentieth-century literature and cultu

Many books explain what is known about the universe. This book investigates what cannot be known. Rather than exploring the amazing facts that science, mathematics, and r

This concise yet comprehensive textbook examines political, social, and cultural developments in the Soviet Union and the post-Soviet period. It begins by identifying the social tensions and political inconsistencies that spurred radical change in Russia's government, from the turn of the century to the revolution of 1917. Peter Kenez presents this revolution as a crisis of authority that the creation of the Soviet Union resolved. The text traces the progress of the Soviet Union through the 1920s, the years of the New Economic Policies, and into the Stalinist order. It illustrates how post-Stalin Soviet leaders struggled to find ways to rule the country without using Stalin's methods - but also without openly repudiating the past - and to negotiate a peaceful but antipathetic coexistence with the capitalist West. This updated third edition includes substantial new material, discussing the challenges Russia currently faces in the era of Putin.

First written in response to a JACT survey of over 100 schools, this textbook has become a standard resource for students throughout the UK and for readers across the world who are looking for a clear and thorough introduction to the language of the ancient Greeks. Now revised throughout and enhanced by colour artwork and text features, this revised edition will support the new OCR specification for Classical Greek (first teaching 2016).Written by a long-time school teacher and examiner, this two-part course is based on experience of what pupils find difficult, concentrating on the essentials and on the understanding of principles in both accidence and syntax: minor irregularities are postponed and subordinated so that the need for rote learning is reduced. It aims to be user-friendly, but also to give pupils a firm foundation for further study. Part 1 covers the basics and is self-contained, with its own reference section. It covers the main declensions, a range of active tenses and a

ABC Animal is an entertaining early learning book with creative and captivating illustrations. Whimsical phrases and bright illustrations will help your preschooler learn the alphabet, names of animal

This Step 2 deluxe Step into Reading leveled reader features The Cat in the Hat Knows a Lot About That!—plus over thirty stickers!It’s Halloween, and the Cat in the Hat is taking Sally and Nick on a trip to find costumes. But when they encounter a colony of tiny cave bats, they are in for a fright—until they learn that most bats are harmless and nothing to be afraid of! Based on the PBS Kids Cat in the Hat Knows a Lot About Halloween! TV special, coming in 2016, this early reader with over thirty stickers is the perfect way for kids to celebrate the holiday—and learn a bit about an iconic Halloween animal!Step 2 Readers use basic vocabulary and short sentences to tell simple stories. For children who recognize familiar words and can sound out new words with help.

The five gently spine-tingling, funny stories in this Level Two I Can Read box set are sure to delight early readers. Titles include: Flat Stanley and the Haunted House Monster School: First Day Fri

Ranger, the time-traveling golden retriever with search-and-rescue training, joins an early twentieth-century expedition journeying from New Zealand to Antarctica. He befriends Jack Nin, the stowaway

Explore the history of Ellis Island, one of the most recognized landmarks in American history. Kids will learn about its early history as a Mohegan island and rest spot for fishermen through its time

This pocket-sized, practical guide has everything the acrylic artist needs to know about color mixing, from color theory to complementary, warm and cool colors, color tone, using a limited palette, dull and bright colors and local color. There follows an array of essential color mixes using widely available Winsor & Newton colors. Clear, practical and beautifully presented advice.

Claudia and her sister, Janine, may as well be from two different planets. Claudia, who pays more attention to her artwork and The Baby-sitters Club than her homework, feels like she can't compete with her perfect sister. Janine studies nonstop, gets straight As, and even takes college-level courses! But when something unexpected happens to the most beloved person in their family, will the sisters be able to put aside their differences?Raina Telgemeier, using the signature style featured in her acclaimed graphic novelsSmile and Sisters, perfectly captures all the drama and charm of the original novel!

DescriptionThe Wolf and the Seven Children Level 3-3Mother Goat goes out for the day. Her seven children are home. They know not to open the door. But the Wolf has an idea to get in!Early readers will

"Discusses the science of gymnastics, using biology, physics and engineering"--

Big Data（大數據）在這幾年突然開始被掛在行銷廣告、學者研究，甚至上班族的日常工作中，而大數據特性包含三種層面：巨量、即時性及多樣性。早期其實就存在許多透過資料來佐證或者分析預測結果的例子，但伴隨著全球化的網路效應及社群網站的發展，資料的數量已達到一般方式無法負荷的境界，因此有了Big Data這個名詞。 在人人都想談論Big Data的時代，大家都想使用它，但應該如何有效地使用則是一門大學

Level: EYFSSubject: English An engaging Writing activity book to really help boost your child's progress at every stage of their learning! Fully in line with the Early Years Foundation Stage,

Heidi Heckelbeck wants to prove she can make it in the babysitting business, but she’ll need a little magic and a lot of help from her friends!Heidi Heckelbeck is eager to start babysitting, but her mom doesn’t think she’s old enough yet. To prove she’s ready to be responsible, Heidi teams up with Laurel and Bruce to create a spectacular booth—called the “Little Explorers Museum”—for the Brewster Elementary fair. It’s going to be an exciting exhibit of fabulous art projects, nifty science experiments…and babysitting! But when Heidi worries that her babysitting station won’t attract enough visitors, will her Book of Spells help her find a magical solution?With easy-to-read language and illustrations on almost ever page, the Heidi Heckelbeck chapter books are perfect for beginning readers.

Bugis Street was famous (or notorious) for being a haunt of transgender prostitution in the early decades of postcolonial Singapore. Since then the site has been a source of touristic obsession and lo

This heartwarming book encourages positive behavior by using the concept of an invisible bucket to show children how easy and rewarding it is to express kindness, appreciation, and love by "filling bu

Learning to read is fun with the Rainbow Magic Fairies! Developed in conjunction with Early Years reading consultants and based on the most up-to-date educational research, the Rainbow Magic Beginner

Welcome to Stately Academy, a school which is just crawling with mysteries to be solved! The founder of the school left many clues and puzzles to challenge his enterprising students. Using their wits

本書特色 雲端運算是基於網際網路的運算方式，它通過網際網路為個人使用者或企業使用者提供按需即取的服務。隨著電腦技術的發展，資料的存儲量成倍的增長，Data Mining 技術在“資料海洋、知識荒漠”的背景下應運而生的，並且一經出現就得到各個領域的重視。隨著Data Mining 的逐漸成熟，以Data Mining 為核心的Business Intelligence（BI）已經成為了IT 和其他行

The invention of clocks and calendars has been very important in shaping the progress of human civilisation. This book tells their story, from early timekeeping methods and devices, and the formation

Comical adventure and silly mishaps are hallmarks of Richard Scarry’s stories, and this Step 2 early reader delivers both. Smokey the fireman puts out fires with his fire truck, but when he’s in the c